2004年6月
Transformation of zirconocene-olefin complexes into zirconocene allyl hydride and their use as dual nucleophilic reagents: Reactions with acid chloride and 1,4-diketone
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- ,
- ,
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- 巻
- 126
- 号
- 21
- 開始ページ
- 6776
- 終了ページ
- 6783
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/ja049184y
- 出版者・発行元
- AMER CHEMICAL SOC
Zirconocene-olefin complexes Cp2Zr(H2C=CHR), prepared in benzene-THF at 0 degreesC, react with acid chlorides to provide homoallylic alcohols. The key is an equilibrium between the zirconocene-olefin complexes and the corresponding zirconocene allyl hydride complexes via allylic C-H bond cleavage of the coordinating alkenes. Furthermore, the zirconocene-olefin complexes are also available for the reaction with 1,4-diketone to afford anti-1,4-diols with excellent diastereoselectivity. Thus, Cp2Zr(H2C CHR) serves as a donor of both hydride and an allylic group. These reactions also proceed efficiently by using zirconocene-olefin complexes, derived from Cp2ZrCl2, Mg metal, and 1-alkenes.
- リンク情報
-
- DOI
- https://doi.org/10.1021/ja049184y
- J-GLOBAL
- https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902286775100373
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/15161306
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000221671400058&DestApp=WOS_CPL
- URL
- http://orcid.org/0000-0002-0153-1888
- ID情報
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- DOI : 10.1021/ja049184y
- ISSN : 0002-7863
- J-Global ID : 200902286775100373
- ORCIDのPut Code : 27822211
- PubMed ID : 15161306
- Web of Science ID : WOS:000221671400058