輪千浩史 (Hiroshi Wachi) - マイポータル - researchmap

基本情報

所属: 星薬科大学薬学部衛生薬学科講師

学位: 博士(薬学)

J-GLOBAL ID: 200901040667900670
researchmap会員ID: 1000289224

研究キーワード

6

研究分野

4

受賞

1

2000年

星薬科大学大谷記念研究助成金

MISC

20

Nitric oxide stimulates elastin expression in chick aortic smooth muscle cells

Biol. Pharm. Bull. 24(5) 461-464 2001年
腹部大動脈瘤における組織中のエラスチン、フィブリリンおよびコラーゲンの変動

越阪部徹, 岡田なぎさ, 輪千浩史, 佐藤成, 佐々木茂, 和田直文, 瀬山義幸

日本老年医学雑誌 37(12) 979-983 2000年
Quantitative changes of elastin, fibrillin and collagen in abdominal aortic aneurysms.

Toru Osakabe, Nagisa Okada, Hiroshi Wachi, Akira Sato, Shigeru Sasaki, Naofumi Wada, Yoshiyuki Seyama

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics 37(12) 979-983 2000年
Characterization of an in vitro model off elastic fiber assembly

BW Robb, H Wachi, T Schaub, RP Mecham, EC Davis

MOLECULAR BIOLOGY OF THE CELL 10(11) 3595-3605 1999年11月
An open reading frame element mediates posttranscriptional regulation of tropoelastin and responsiveness to transforming growth factor beta 1

MC Zhang, RA Pierce, H Wachi, RP Mecham, WC Parks

MOLECULAR AND CELLULAR BIOLOGY 19(11) 7314-7326 1999年11月
Increase in elastin gene expression and protein synthesis in arterial smooth muscle cells derived from patients with moyamoya disease

M Yamamoto, M Aoyagi, S Tajima, H Wachi, N Fukai, Y Matsushima, K Yamamoto

STROKE 28(9) 1733-1738 1997年9月
Modulation by elastin peptide VGVAPG of cell proliferation and elastin expression in human skin fibroblasts

S Tajima, H Wachi, Y Uemura, K Okamoto

ARCHIVES OF DERMATOLOGICAL RESEARCH 289(8) 489-492 1997年7月
Effects of monensin on tropoelastin metabolism in vascular smooth muscle cells: Monensin causes intracellular degradation of accumulated tropoelastin

K Ikeda, H Wachi, Y Seyama, S Tajima

JOURNAL OF BIOCHEMISTRY 121(1) 5-7 1997年1月
ヒト皮膚線維芽細胞におけるエラスチン遺伝子のalternative splicing -加齢による制御-

28 21-25 1996年
Tropoelastin-derived degradation products downregulate elastin expression in vascular smooth muscle cell in culture

Connect. Tissue. 28 231-235 1996年
Alternative splicing of elastin mRNA in Human skin fibroblasts. -Modulation by donor aging-

Connect. Tissue 28 21-25 1996年
MODULATION OF ELASTIN EXPRESSION BY HEPARIN IS DEPENDENT ON THE GROWTH CONDITION OF VASCULAR SMOOTH-MUSCLE CELLS - UP-REGULATION OF ELASTIN EXPRESSION BY HEPARIN IN THE PROLIFERATING CELLS IS MEDIATED BY THE INHIBITION OF PROTEIN-KINASE-C ACTIVITY

H WACHI, Y SEYAMA, S TAJIMA

JOURNAL OF BIOCHEMISTRY 118(3) 582-586 1995年9月
STIMULATION OF CELL-PROLIFERATION AND AUTOREGULATION OF ELASTIN EXPRESSION BY ELASTIN PEPTIDE VPGVG IN CULTURED CHICK VASCULAR SMOOTH-MUSCLE CELLS

H WACHI, Y SEYAMA, S YAMASHITA, H SUGANAMI, Y UEMURA, K OKAMOTO, H YAMADA, S TAJIMA

FEBS LETTERS 368(2) 215-219 1995年7月
CELL CYCLE-DEPENDENT REGULATION OF ELASTIN GENE IN CULTURED CHICK VASCULAR SMOOTH-MUSCLE CELLS

H WACHI, Y SEYAMA, S YAMASHITA, S TAJIMA

BIOCHEMICAL JOURNAL 309(2) 575-579 1995年7月
PRESENCE OF ELASTIN-RELATED 45-KDA FRAGMENT IN CULTURE-MEDIUM - SPECIFIC CLEAVAGE PRODUCT OF TROPOELASTIN IN VASCULAR SMOOTH-MUSCLE CELL-CULTURE

A HAYASHI, H WACHI, S TAJIMA

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1244(2-3) 325-330 1995年6月
ENHANCED TROPOELASTIN-DEGRADING ACTIVITY DURING CELL PASSAGES IN CULTURED SMOOTH-MUSCLE CELLS

H WACHI, Y SEYAMA, S YAMASHITA, S TAJIMA

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1243(3) 393-398 1995年4月
Accumulation of tropoelastin by a short-term ascorbic acid treatment in the culture medium of aortic smooth muscle cells in vitro

Shingo Tajima, Hiroshi Wachi, Akinobu Hayashi

The Keio Journal of Medicine 44(4) 140-145 1995年
Post-translational regulation of type (]G0001[) collagen synthesis by heparin in vascular smooth muscle cells.

J. Biochem. 117 353-358 1995年
Elastin synthesis is inhibited by angiotensin (]G0002[) but not by platelet-derived growth factor in arterial smooth muscle cells

Biochim. Biophys. Acta, 1207(1) 68-73 1994年
Minoxidil stimulates elastin expression in aortic smooth muscle cells.

Arch. Biochem. Biophys. 315(1) 137-141 1994年

所属学協会

4

共同研究・競争的資金等の研究課題

6