Akira Onoda

Profile Information

Affiliation: Faculty of Environmental Earth Science, Hokkaido University

Degree: (BLANK)(Mar, 2002, Osaka University)

Researcher number: 60366424
J-GLOBAL ID: 200901023427309230
researchmap Member ID: 1000297590

External link: https://onoda-lab.jp/

Research Interests

Research Areas

Education

- Mar, 2002

Graduate School of Science, Osaka University
- 1999

Osaka University

Papers

Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold

Shunsuke Kato, Akira Onoda, Ulrich Schwaneberg, Takashi Hayashi

Journal of the American Chemical Society, Mar 9, 2023
Thermally Controlled Construction of Fe-Nx Active Sites on the Edge of a Graphene Nanoribbon for an Electrocatalytic Oxygen Reduction Reaction

Koki Matsumoto, Akira Onoda, Tomoyuki Kitano, Takao Sakata, Hidehiro Yasuda, Stéphane Campidelli, Takashi Hayashi

ACS Applied Materials and Interfaces, 13(13) 15101-15112, Apr, 2021 Peer-reviewedCorresponding author
Construction of a whole-cell biohybrid catalyst using a Cp*Rh(III)-dithiophosphate complex as a precursor of a metal cofactor

Shunsuke Kato, Akira Onoda, Alexander R. Grimm, Ulrich Schwaneberg, Takashi Hayashi

Journal of Inorganic Biochemistry, 216, Mar, 2021 Peer-reviewedCorresponding author
Directed Evolution of a Cp*Rh^III-Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification

Shunsuke Kato, Akira Onoda, Naomasa Taniguchi, Ulrich Schwaneberg, Takashi Hayashi

ChemBioChem, 22(4) 679-685, Feb 15, 2021 Peer-reviewedCorresponding author
Incorporation of a Cp*Rh(III)-dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp²)-H Bond Functionalization

Shunsuke Kato, Akira Onoda, Alexander R. Grimm, Kengo Tachikawa, Ulrich Schwaneberg, Takashi Hayashi

Inorganic Chemistry, 59(19) 14457-14463, Oct 5, 2020 Peer-reviewedCorresponding author
Chiral paddle-wheel diruthenium complexes for asymmetric catalysis

Taku Miyazawa, Takuro Suzuki, Yuhei Kumagai, Koji Takizawa, Takashi Kikuchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi, Yuji Kamei, Futa Kamiyama, Masahiro Anada, Masahiro Kojima, Tatsuhiko Yoshino, Shigeki Matsunaga

Nature Catalysis, 3(10) 851-858, Oct 1, 2020 Peer-reviewed
Triazolecarbaldehyde Reagents for One-Step N-Terminal Protein Modification

Akira Onoda, Nozomu Inoue, Eigo Sumiyoshi, Takashi Hayashi

ChemBioChem, 21(9) 1274-1278, May 4, 2020 Peer-reviewedCorresponding author
Site-Specific Modification of Proteins through N-Terminal Azide Labeling and a Chelation-Assisted CuAAC Reaction

Nozomu Inoue, Akira Onoda, Takashi Hayashi

Bioconjugate Chemistry, 30(9) 2427-2434, Sep 18, 2019 Peer-reviewedCorresponding author
Hemoproteins Reconstituted with Artificial Metal Complexes as Biohybrid Catalysts

Koji Oohora, Akira Onoda, Takashi Hayashi

Accounts of Chemical Research, 52(4) 945-954, Apr, 2019 Peer-reviewed
Artificially Created Metalloenzyme Consisting of an Organometallic Complex Immobilized to a Protein Matrix

Daniel F. Sauer, Takashi Matsuo, Akira Onoda, Jun Okuda, Takashi Hayashi

Advances in Bioorganometallic Chemistry, 307-328, Dec 6, 2018
Titelbild: A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction (Angew. Chem. 44/2017)

Tomoki Himiyama, Naomasa Taniguchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi

Angewandte Chemie, 129(44) 13719, Oct, 2017 Peer-reviewed
Cover Picture: A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction (Angew. Chem. Int. Ed. 44/2017)

Tomoki Himiyama, Naomasa Taniguchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi

Angewandte Chemie International Edition, 56(44) 13533, Oct, 2017 Peer-reviewed
A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels-Alder Reaction

Tomoki Himiyama, Naomasa Taniguchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi

Angewandte Chemie, 129(44) 13806, Oct, 2017 Peer-reviewed
A supramolecular assembly based on an engineered hemoprotein exhibiting a thermal stimulus-driven conversion to a new distinct supramolecular structure

Koji Oohora, Yoshitaka Onuma, Yuta Tanaka, Akira Onoda, Takashi Hayashi

Chemical Communications, 53(51) 6879-6882, 2017 Peer-reviewed
Enhanced visible light response of a WO<inf>3</inf> photoelectrode with an immobilized fibrous gold nanoparticle assembly using an amyloid-β peptide

Akira Onoda, Hirofumi Harada, Taro Uematsu, Susumu Kuwabata, Ryo Yamanaka, Shinichi Sakurai, Takashi Hayashi

RSC Advances, 7(2) 1089-1092, 2017 Peer-reviewed
A supramolecular assembly based on an engineered hemoprotein exhibiting a thermal stimulus-driven conversion to a new distinct supramolecular structure

Koji Oohora, Yoshitaka Onuma, Yuta Tanaka, Akira Onoda, Takashi Hayashi

Chemical Communications, 53(51) 6879-6882, 2017 Peer-reviewed
Anchoring Cytochrome b<inf>562</inf>on a Gold Nanoparticle by a Heme–Heme Pocket Interaction

Akira Onoda, Tomoaki Taniguchi, Nozomu Inoue, Ayumi Kamii, Takashi Hayashi

European Journal of Inorganic Chemistry, 2016(21) 3454-3459, Jul, 2016 Peer-reviewed
Photocatalytic Properties of TiO<inf>2</inf> Composites Immobilized with Gold Nanoparticle Assemblies Using the Streptavidin-Biotin Interaction

Hirofumi Harada, Akira Onoda, Taro Uematsu, Susumu Kuwabata, Takashi Hayashi

Langmuir, 32(25) 6459-6467, Jun 28, 2016 Peer-reviewed
Artificial Diels-Alderase based on the transmembrane protein FhuA

Hassan Osseili, Daniel F. Sauer, Klaus Beckerle, Marcus Arlt, Tomoki Himiyama, Tino Polen, Akira Onoda, Ulrich Schwaneberg, Takashi Hayashi, Jun Okuda

Beilstein Journal of Organic Chemistry, 12 1314-1321, Jun 24, 2016 Peer-reviewed
Construction of a hybrid biocatalyst containing a covalently-linked terpyridine metal complex within a cavity of aponitrobindin

Tomoki Himiyama, Daniel F. Sauer, Akira Onoda, Thomas P. Spaniol, Jun Okuda, Takashi Hayashi

Journal of Inorganic Biochemistry, 158 55-61, May 1, 2016 Peer-reviewed

Misc.

A Heterogeneous Hydrogen-Evolution Catalyst Based on a Mesoporous Organosilica with a Diiron Catalytic Center Modelling [FeFe]-Hydrogenase

Tomoki Himiyama, Minoru Waki, Dolores Esquivel, Akira Onoda, Takashi Hayashi, Pascal Van Der Voort, Shinji Inagaki

ChemCatChem, 10(21) 4908-4913, Nov 7, 2018
Cavity Size Engineering of a β-Barrel Protein Generates Efficient Biohybrid Catalysts for Olefin Metathesis

Alexander R. Grimm, Daniel F. Sauer, Mehdi D. Davari, Leilei Zhu, Marco Bocola, Shunsuke Kato, Akira Onoda, Takashi Hayashi, Jun Okuda, Ulrich Schwaneberg

ACS Catalysis, 8(4) 3358-3364, Apr, 2018
Nonprecious-metal Fe/N/C Catalysts Prepared from π-Expanded Fe Salen Precursors toward an Efficient Oxygen Reduction Reaction

Yuta Tanaka, Akira Onoda, Shin-Ichi Okuoka, Tomoyuki Kitano, Koki Matsumoto, Takao Sakata, Hidehiro Yasuda, Takashi Hayashi

ChemCatChem, 10(4) 743-750, Feb 21, 2018 Corresponding author
A water-soluble supramolecular complex that mimics the heme/copper hetero-binuclear site of cytochrome: C oxidase

Hiroaki Kitagishi, Daiki Shimoji, Takehiro Ohta, Ryo Kamiya, Yasuhiro Kudo, Akira Onoda, Takashi Hayashi, Jean Weiss, Jennifer A. Wytko, Koji Kano

Chemical Science, 9(7) 1989-1995, Feb 21, 2018
Mitochondria-Targeting Polyamine–Protoporphyrin Conjugates for Photodynamic Therapy

Fargol Taba, Akira Onoda, Urara Hasegawa, Toshiaki Enoki, Yousuke Ooyama, Joji Ohshita, Takashi Hayashi

ChemMedChem, 13(1) 15-19, Jan 8, 2018
Bimetallic M/N/C catalysts prepared from π-expanded metal salen precursors toward an efficient oxygen reduction reaction

Akira Onoda, Yuta Tanaka, Koki Matsumoto, Minoru Ito, Takao Sakata, Hidehiro Yasuda, Takashi Hayashi

RSC Advances, 8(6) 2892-2899, 2018
A Pyrene-Linked Cavity within a β-Barrel Protein Promotes an Asymmetric Diels–Alder Reaction

Tomoki Himiyama, Naomasa Taniguchi, Shunsuke Kato, Akira Onoda, Takashi Hayashi

Angewandte Chemie - International Edition, 56(44) 13618-13622, Oct 23, 2017
Cofactor-specific anchoring of horseradish peroxidase onto a polythiophene-modified electrode

Akira Onoda, Yasunari Umeda, Takashi Hayashi

Chemistry Letters, 46(12) 1818-1821, 2017
Interdomain flip-flop motion visualized in flavocytochrome cellobiose dehydrogenase using high-speed atomic force microscopy during catalysis

Hirofumi Harada, Akira Onoda, Takayuki Uchihashi, Hiroki Watanabe, Naoki Sunagawa, Masahiro Samejima, Kiyohiko Igarashi, Takashi Hayashi

Chemical Science, 8(9) 6561-6565, 2017
In Situ Observation of Enhanced Photoinduced Charge Separation in a Gold Nanoparticle Assembly Immobilized on TiO<inf>2</inf>

Hirofumi Harada, Akira Onoda, Shiho Moriguchi, Takashi Hayashi

ChemistrySelect, 1(18) 5666-5670, Nov 1, 2016
ヘムを介して配向担持されたセロビオースデヒドロゲナーゼ修飾バイオ電極の構築

原田裕史, 小野田晃, 砂川直輝, 五十嵐圭日子, 林高史

錯体化学会討論会講演要旨集, 65th, 2015
A Rhodium Complex-Linked beta Barrel Protein as a Hybrid Biocatalyst for Phenylacetylene Polymerization

A. Onoda, K. Fukumoto, T. Hayashi

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 19 S569-S569, Mar, 2014
Crystal structure and spectroscopic studies of a stable mixed-valent state of the hemerythrin-like domain of a bacterial chemotaxis protein

Akira Onoda, Yasunori Okamoto, Hiroshi Sugimoto, Yoshitsugu Shiro, Takashi Hayashi

Inorganic Chemistry, 50(11) 4892-4899, Jun 6, 2011
Crystal structure and spectroscopic studies of a stable mixed-valent state of the hemerythrin-like domain of a bacterial chemotaxis protein

Akira Onoda, Yasunori Okamoto, Hiroshi Sugimoto, Yoshitsugu Shiro, Takashi Hayashi

Inorganic Chemistry, 50(11) 4892-4899, Jun 6, 2011
A chemically-controlled supramolecular protein polymer formed by a myoglobin-based self-assembly system

Koji Oohora, Akira Onoda, Hiroaki Kitagishi, Hiroyasu Yamaguchi, Akira Harada, Takashi Hayashi

Chemical Science, 2(6) 1033-1038, Jun, 2011
Preparation and reactivity of a tetranuclear Fe(II) core in the metallothionein alpha-domain

Yohei Sano, Akira Onoda, Rie Sakurai, Hiroaki Kitagishi, Takashi Hayashi

JOURNAL OF INORGANIC BIOCHEMISTRY, 105(5) 702-708, May, 2011
Preparation and reactivity of a tetranuclear Fe(II) core in the metallothionein alpha-domain

Yohei Sano, Akira Onoda, Rie Sakurai, Hiroaki Kitagishi, Takashi Hayashi

JOURNAL OF INORGANIC BIOCHEMISTRY, 105(5) 702-708, May, 2011
A hydrogenase model system based on the sequence of cytochrome c: photochemical hydrogen evolution in aqueous media

Yohei Sano, Akira Onoda, Takashi Hayashi

CHEMICAL COMMUNICATIONS, 47(29) 8229-8231, 2011
A chemically-controlled supramolecular protein polymer formed by a myoglobin-based self-assembly system

Koji Oohora, Akira Onoda, Hiroaki Kitagishi, Hiroyasu Yamaguchi, Akira Harada, Takashi Hayashi

CHEMICAL SCIENCE, 2(6) 1033-1038, 2011
A hydrogenase model system based on the sequence of cytochrome c: Photochemical hydrogen evolution in aqueous media

Chem. Commun., 2011

Books and Other Publications

“Artificial Metalloenzymes Containing an Organometallic Active Site”, In Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging.

A. Onoda, T. Hayashi, M. Salmain (Role: Joint author)

Wiley-VCH, Dec, 2014 (ISBN: 9783527335275)

Professional Memberships

Apr, 2002 - Present

Japan Society of Coordination Chemistry
アメリカ化学会
高分子学会
日本化学会

Works

Research Projects

Construction of a Structural and/or Functional Model of New Light-harvesting System Using Artificial Hemoprotein Assembly

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2024
指向性進化工学を駆使したRh連結バイオハイブリッド触媒の開発

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2020 - Mar, 2022

小野田晃
カーボンエッジ配位化学に立脚した非貴金属カーボン電極触媒の開拓

科学研究費助成事業挑戦的研究(萌芽), 日本学術振興会, Jun, 2019 - Mar, 2021

小野田晃
アシンメトリー配位圏を有するバレル型バイオハイブリッド触媒を活用した反応開拓

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2019 - Mar, 2021

小野田晃
金属錯体を微生物の細胞表面に固定化した高選択的バイオハイブリッド触媒系の開発

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2018 - Mar, 2020

小野田晃
An biohybrid catalyst containg an asymmetric coordination sphere embedded within a beta barrel protein

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2019
A transition state of biologically relevant Fe hydride: Reactivity studies in a protein cavity

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Jul, 2015 - Mar, 2019

Onoda Akira, Hayashi Takashi, Himiyama Tomoki, Tachikawa Kengo, Aoki Ayumi
Development of High Performance Biohybrid Catalyst by Directed Evolution(Fostering Joint International Research)

Grants-in-Aid for Scientific Research Fund for the Promotion of Joint International Research (Fostering Joint International Research), Japan Society for the Promotion of Science, 2017 - 2019

Onoda Akira
Development of non-precious metal carbon electrocatalysts for polymer electrolyte fuel cell by biomimetic approaches

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Onoda Akira, Hayashi Takashi, Tanaka Yuta, Ito Minoru
Development of suramolecular recruiting technology for elucidation of dynamics of protein assemblies involved in cell division

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Onoda Akira, HAYASHI Takashi
金属タンパク質と合成ポリマーから構成される機能性ハイブリッド界面の開発

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2015 - Mar, 2017

小野田晃
金属タンパク質と金属ナノ粒子の階層化によるハイブリッド界面の構築

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2013 - Mar, 2016

小野田晃
Non-Precious Metal Carbon Catalysts containing Multinuclear Active SItes

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Onoda Akira, Hayashi Takashi
Construction of a New Catalyst Using a Protein Matrix

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2010 - Mar, 2016

Hayashi Takashi, ONODA Akira
ヘムタンパク質を活用した異種タンパク質階層プログラミングとバイオデバイスへの展開

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2012 - Mar, 2015

小野田晃
Construction of Artificial Biocatalysts containing Non-natural Dimetallic Active Site

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2011 - 2012

ONODA Akira, TAHASHI Takashi
ヘムタンパク質階層プログラミングによる機能性デバイスの創製

科学研究費助成事業新学術領域研究(研究領域提案型), 日本学術振興会, 2010 - 2011

小野田晃
Construction of Artificial Biocatalysts containing a Nonnatural Dinuclear Active Site

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2010

ONODA Akira
Supramolecular alignment of the functionalities of coordination compounds and quantum dot clusters at will on DNA. Use of zinc finger motifs.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2006 - 2008

YAMAMURA Takeshi, ONODA Akira, SAKAMOTO Ryouta
カルシウムセンサー機能を有する人工DNA結合タンパク質の精密構築

科学研究費助成事業若手研究(B), 日本学術振興会, 2006 - 2007

小野田晃

Major Industrial Property Rights

特願2020-126563 微小粒子の製造方法

林高史, 小野田晃, 加藤俊介
PCT/JP2020/008357 MOLECULE FOR PROTEIN AND/OR PEPTIDE DESIGN

Takashi Hayashi, Akira Onoda, Nozomu Inoue
特開2019-052117 金属複合体

林高史, 小野田晃, 松元香樹, 郷田隼, 小野博信, 北野友之
特開2019-052116 含窒素多環式化合物

林高史, 小野田晃, 松元香樹, 郷田隼, 小野博信, 北野友之
PCT/JP2019/008142 MOLECULE FOR PROTEIN AND/OR PEPTIDE DESIGN

Takashi Hayashi, Akira Onoda, Nozomu Inoue
特願2019-035340 MOLECULE FOR PROTEIN AND/OR PEPTIDE DESIGN

Takashi Hayashi, Akira Onoda, Nozomu Inoue

Profile Information

Research Interests

Research Areas

Education

Papers

Misc.

Books and Other Publications

Professional Memberships

Works

Research Projects

Major Industrial Property Rights

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