J-GLOBAL         Last updated: May 10, 2013 at 10:15
Jichi Medical University
School of Medicine, Division of Environmental Medicine, Center for Community Medicine
Job title
Associate Professor
(BLANK)(*Toyama Medical and Pharmaceutical University*)

Research Areas


Academic & Professional Experience

Apr 2011
associate professor, Akita University
Jichi Medical University
Fukushima Medical University


Graduate School, Division of Medicine, Toyama Medical and Pharmaceutical University
Faculty of Medicine, Toyama Medical and Pharmaceutical University

Published Papers

Horiguchi H, Oguma E, Sasaki S, Okubo H, Murakami K, Miyamoto K, Hosoi Y, Murata K, Kayama F.
Environ Int   56 1-9   2013   [Refereed]
Arch Toxicol   80 680-686   2006   [Refereed]
Horiguchi H, Oguma E, Sasaki S, Miyamoto K, Ikeda Y, Machida M, Kayama F.
Environ Res   97(1) 83-92   2005   [Refereed]
Horiguchi H, Oguma E, Nomoto S, Arao Y, Ikeda K, Kayama F.
Toxicol Lett   151 459-466   2004   [Refereed]
Horiguchi H, Oguma E, Sasaki S, Miyamoto K, Ikeda Y, Machida M, Kayama F.
Toxcol Appl Pharmacol   196 114-123   2004   [Refereed]
Horiguchi H, Oguma E, Sasaki S, Miyamoto K, Ikeda Y, Machida M, Kayama F.
Environ Res   95(1) 20-31   2004   [Refereed]
Horiguchi H, Oguma E, Kayama F, Satoh M, Fukushima M.
Toxicol Appl Pharmacol   174(3) 225-234   2001   [Refereed]
Horiguchi H, Bunn HF.
Bioch Biophys Acta   1495 231-236   2000   [Refereed]
Cadmium and platinum suppression of erythropoietin production in cell culture: Clinical implications.
Horiguchi H, Kayama F, Oguma E, Willmore WG, Hradecky P, Bunn HF.
Blood   96 3743-3747   2000   [Refereed]
Horiguchi H, Harada A, Oguma E, Sato M, Homma Y, Kayama F, Fukushima M, Matsushima K.
Toxicol Appl Pharmacol   163(3) 231-239   2000   [Refereed]
Horiguchi H, Sato M, Konno N, Fukushima M.
Arch Toxicol   71(1/2) 11-19   1996   [Refereed]
Horiguchi H, Teranishi H, Niiya K, Aoshima K, Katoh T, Sakuragawa N, Kasuya M.
Arch Toxicol   68(10) 632-636   1994   [Refereed]
Cadmium induces interleukin-8 production in human peripheral blood mononuclear cells with concomitant generation of superoxide radicals.
Horiguchi H, Mukaida N, Okamoto S, Teranishi H, Kasuya M, Matsushima K.
Lymphokine Cytokine Res   12 421-428   1993   [Refereed]


Delayed Neurotoxicity of Diisopropylfluorophosphate(DFP) : Autoradiographic localization of high-affinity [3H] DFP binding sites in the chicken spinal cord.
Environmental Health and Preventive Medicine.   4 92-96   1999
The interleukin-8 AP-1 and kB-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization.
The Journal of Biological Chemistry.   269(11) 8582-8589   1994
Molecular analysis of the transcriptional regulation of the IL 8 gene and establishment of essential roles of IL 8 in acute inflammation. In J. Navaro(Ed) Molecular Basis of Inflammation, Challenges of Modern Medicine
Ares-Sereno Symposia Publications   3 155-161   1994
Molecular mechanism of interleukin 8 gene expression. In Lindley, I. J. D. , Westwick, J. , Kunkel, S. L. (ED) Chemokines
Proceeding of IIIrd International Symposium of Chemotactic Cytokines   87-97   1993
Water pollution by cadmium and the onset of Itai-itai disease.
Wat. Sci. Tech.   25(11) 149-156   1992
A fifteen-year follow-up sudy on renal dysfuntion among people living in cadmium-polluted area.
Wat. Sci. Tech.   25(11) 157-164   1992

Research Grants & Projects

Study on cadmium toxicity and erythropoietin
Study on the role of inflammation in Codmium toxicity
Study on the effect of anvironmental disruptors on erythropoiein prodnction
JST Basic Research Programs (Core Research for Evolutional Science and Technology :CREST)
Project Year: 2000   
The health effects of low-dose cadmium exposure in human beings
Health and Labour Sciences Research Grants
Project Year: 2000