土井俊夫 (Toshio Doi) - マイポータル

基本情報

所属: 徳島大学医学部医学科病態情報医学講座病態情報診断学分野教授

学位: 博士(医学)(京都大学)

J-GLOBAL ID: 200901025261658241
researchmap会員ID: 1000300239

研究キーワード

研究分野

委員歴

論文

Protein inhibitor of activated STAT, PIASy regulates α-smooth muscle actin expression by interacting with E12 in mesangial cells.

Torikoshi K, Abe H, Matsubara T, Hirano T, Ohshima T, Murakami T, Araki M, Mima A, Iehara N, Fukatsu A …

PloS one 7(7) e41186 2012年7月査読有り
Scleraxis modulates bone morphogenetic protein 4 (BMP4)-Smad1 protein-smooth muscle α-actin (SMA) signal transduction in diabetic nephropathy.

Abe H, Tominaga T, Matsubara T, Abe N, Kishi S, Nagai K, Murakami T, Araoka T, Doi T

The Journal of biological chemistry 287(24) 20430-20442 2012年6月査読有り
SOX9 Protein Induces a Chondrogenic Phenotype of Mesangial Cells and Contributes to Advanced Diabetic Nephropathy

Seiji Kishi, Hideharu Abe, Haruhiko Akiyama, Tatsuya Tominaga, Taichi Murakami, Akira Mima, Kojiro Nagai, Fumi Kishi, Motokazu Matsuura, Takeshi Matsubara …

JOURNAL OF BIOLOGICAL CHEMISTRY 286(37) 32162-32169 2011年9月査読有り
Activation of Bone Morphogenetic Protein 4 Signaling Leads to Glomerulosclerosis That Mimics Diabetic Nephropathy

Tatsuya Tominaga, Hideharu Abe, Otoya Ueda, Chisato Goto, Kunihiko Nakahara, Taichi Murakami, Takeshi Matsubara, Akira Mima, Kojiro Nagai, Toshikazu Araoka …

JOURNAL OF BIOLOGICAL CHEMISTRY 286(22) 20109-20116 2011年6月査読有り
Role of Smad1 in diabetic nephropathy: Molecular mechanisms and implications as a diagnostic marker

Hideharu Abe, Takeshi Matsubara, Hidenori Arai, Toshio Doi

HISTOLOGY AND HISTOPATHOLOGY 26(4) 531-541 2011年4月査読有り
Activation of Src Mediates PDGF-Induced Smad1 Phosphorylation and Contributes to the Progression of Glomerulosclerosis in Glomerulonephritis

Akira Mima, Hideharu Abe, Kojiro Nagai, Hidenori Arai, Takeshi Matsubara, Makoto Araki, Kazuo Torikoshi, Tatsuya Tominaga, Noriyuki Iehara, Atsushi Fukatsu …

PLOS ONE 6(3) e17929 2011年3月査読有り
MPO-ANCA-Positive Anti-glomerular Basement Membrane Antibody Disease Successfully Treated by Plasma Exchange and Immunosuppressive Therapy

Taichi Murakami, Kojiro Nagai, Motokazu Matsuura, Naoki Kondo, Seiji Kishi, Toshikazu Araoka, Fumi Kishi, Tsutomu Sakiyama, Akira Mima, Yoshimi Bando …

RENAL FAILURE 33(6) 626-631 2011年査読有り
An Autopsy Case of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) with Intestinal Bleeding in Chronic Renal Failure

Akira Mima, Fumihiko Shiota, Takeshi Matsubara, Noriyuki Iehara, Taro Akagi, Hideharu Abe, Kojiro Nagai, Motokazu Matsuura, Taichi Murakami, Seiji Kishi …

RENAL FAILURE 33(6) 622-625 2011年査読有り
Transcription Factor 7-Like 2 (TCF7L2) Regulates Activin Receptor-Like Kinase 1 (ALK1)/Smad1 Pathway for Development of Diabetic Nephropathy

Toshikazu Araoka, Hideharu Abe, Tatsuya Tominaga, Akira Mima, Takeshi Matsubara, Taichi Murakami, Seiji Kishi, Kojiro Nagai, Toshio Doi

MOLECULES AND CELLS 30(3) 209-218 2010年9月査読有り
Increasing early insulin secretion compensate adequately for hepatic insulin resistance in CCl4-induced cirrhosis rats

Hidekazu Arai, Naomi Awane, Akira Mizuno, Makiko Fukaya, Masae Sakuma, Nagakatsu Harada, Akihiko Kawaura, Hironori Yamamoto, Hisami Okumura, Yutaka Taketani …

Journal of Medical Investigation 57(1-2) 54-61 2010年2月査読有り
Early Diagnosis and Treatment may Prevent the Development of Complications in an Adult Patient with Glycogen Storage Disease Type Ia

Toshikazu Araoka, Hiroya Takeoka, Hideharu Abe, Seiji Kishi, Makoto Araki, Keisuke Nishioka, Masaki Ikeda, Tetsuro Mazaki, Shiori Ikemura, Makiko Kondo …

INTERNAL MEDICINE 49(16) 1787-1792 2010年査読有り
Trophoblast Glycoprotein: Possible Candidate Mediating Podocyte Injuries in Glomerulonephritis

Taichi Murakami, Hideharu Abe, Kojiro Nagai, Tatsuya Tominaga, Norimichi Takamatsu, Toshikazu Araoka, Seiji Kishi, Toshikazu Takahashi, Akira Mima, Yoshimi Takai …

AMERICAN JOURNAL OF NEPHROLOGY 32(6) 505-521 2010年査読有り
Phosphorylation of Nephrin Triggers Its Internalization by Raft-Mediated Endocytosis

Xiao-Song Qin, Hiroyasu Tsukaguchi, Akemi Shono, Akitsugu Yamamoto, Hidetake Kurihara, Toshio Doi

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 20(12) 2534-2545 2009年12月査読有り
Risk factors for chronic kidney disease in Japan: a community-based study

Norimichi Takamatsu, Hideharu Abe, Tatsuya Tominaga, Kunihiko Nakahara, Yumi Ito, Yoko Okumoto, Jiyoong Kim, Masafumi Kitakaze, Toshio Doi

BMC NEPHROLOGY 10 34 2009年10月査読有り
Improvement of Glucose Metabolism in Patients with Impaired Glucose Tolerance or Diabetes by Long-Term Administration of a Palatinose-Based Liquid Formula as a Part of Breakfast

Masae Sakuma, Hidekazu Arai, Akira Mizuno, Makiko Fukaya, Motoi Matsuura, Hajime Sasaki, Hisami Yamanaka-Okumura, Hironori Yamamoto, Yutaka Taketani, Toshio Doi …

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 45(2) 155-162 2009年9月査読有り
Predisposition to relapsing nephrotic syndrome by a nephrin mutation that interferes with assembly of functioning microdomains

Akemi Shono, Hiroyasu Tsukaguchi, Akiko Kitamura, Ryugo Hiramoto, Xiao-Song Qin, Toshio Doi, Kazumoto Iijima

HUMAN MOLECULAR GENETICS 18(16) 2943-2956 2009年8月査読有り
Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity

Moto Kajiwara, Tomohiro Terada, Ken Ogasawara, Junko Iwano, Toshiya Katsura, Atsushi Fukatsu, Toshio Doi, Ken-ichi Inui

JOURNAL OF HUMAN GENETICS 54(1) 40-46 2009年1月査読有り
Steroid-resistant nephrotic syndrome

Akiko Kitamura, Hiroyasu Tsukaguchi, Kenichi Maruyama, Akemi Shono, Kazumoto Iijima, Shoji Kagami, Toshio Doi

KIDNEY INTERNATIONAL 74(9) 1209-1215 2008年11月査読有り
The current clinical problems for early phase of diabetic nephropathy and approach for pathogenesis of diabetic nephropathy

Toshio Doi, Akira Mima, Takeshi Matsubara, Tatsuya Tominaga, Hidenori Arai, Hideharu Abe

DIABETES RESEARCH AND CLINICAL PRACTICE 82 S21-S24 2008年11月査読有り
Urinary Smad1 is a novel marker to predict later onset of mesangial matrix expansion in diabetic nephropathy

Akira Mima, Hidenori Arai, Takeshi Matsubara, Hideharu Abe, Kojiro Nagai, Yukinori Tamura, Kazuo Torikoshi, Makoto Araki, Hiroshi Kanamori, Toshikazu Takahashi …

DIABETES 57(6) 1712-1722 2008年6月査読有り

もっとみる

MISC

Effect of leptin on insulin sensitivity in the Otsuka Long-Evans Tokushima Fatty rat

Akira Mizuno, Takashi Murakami, Toshio Doi, Kenji Shima

Regulatory Peptides 99(1) 41-44 2001年5月5日
A vitamin D analog ameliorates glomerular injury on rat glomerulonephritis

K Makibayashi, M Tatematsu, M Hirata, N Fukushima, K Kusano, S Ohashi, H Abe, K Kuze, A Fukatsu, T Kita …

AMERICAN JOURNAL OF PATHOLOGY 158(5) 1733-1741 2001年5月
Expression of basic helix-loop-helix proteins in the glomeruli

T Imabayashi, N Iehara, H Takeoka, M Uematsu-Yanagita, H Kataoka, S Nishikawa, H Sano, M Yokode, A Fukatsu, T Kita …

CLINICAL NEPHROLOGY 55(1) 53-58 2001年1月
Influence of the presence of OB-Re on leptin radioimmunoassay

T Murakami, S Otani, T Honjoh, T Doi, K Shima

JOURNAL OF ENDOCRINOLOGY 168(1) 79-86 2001年1月
Gas 6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis

American J of Pathology 158 1423-1431 2001年
A vitamin D analog regulates mesangial cell smooth muscle phenotypes in a transforming growth factor-β type (]G0002[) receptor-mediated manner.

J. Biol. Chem. 274(30) 20874-20878 1999年
Warfarin inhibits Gas6-mediated mesangial proliferation.

J. Am. Soc. Nephrol. 10 2503-2509 1999年
Antisense oligonucleotides against collagen-binding stress protein HSP47 suppress collagen accumulation in experimental glomerulonephritis

M Sunamoto, K Kuze, H Tsuji, N Ohishi, K Yagi, K Nagata, T Kita, T Doi

LABORATORY INVESTIGATION 78(8) 967-972 1998年8月
Advanced glycation end products modulate transcriptional regulation in mesangial cells

N Iehara, H Takeoka, Y Yamada, T Kita, T Doi

KIDNEY INTERNATIONAL 50(4) 1166-1172 1996年10月
RECEPTOR-SPECIFIC INCREASE IN EXTRACELLULAR-MATRIX PRODUCTION IN MOUSE MESANGIAL CELLS BY ADVANCED GLYCOSYLATION END-PRODUCTS IS MEDIATED VIA PLATELET-DERIVED GROWTH-FACTOR

T DOI, H VLASSARA, M KIRSTEIN, Y YAMADA, GE STRIKER, LJ STRIKER

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(7) 2873-2877 1992年4月
Glomerulosclerosis in mice transgenic for growth hormone. Increased mesangial extracellular matrix is correlated with kidney mRNA levels.

J. Exp. Med. 173(5) 1287-1290 1991年
Giomerular lesions of the non-obese diabetic (NOD) mouse ; before and after the onset of hyperglycemia.

Lab. Invest. 63 204-212 1990年
Insulinlike growth factor-1 is a progression factor for human mesangial cells.

Am. J. Pathol. 134 395-404 1989年
Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-1.

Am. J. Pathol. 131 398-403 1988年

土井俊夫

基本情報

研究キーワード

研究分野

委員歴

論文

MISC

所属学協会

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