Ryuichi Yamamoto

Profile Information

Degree: Ph.D.(Kurume University)

J-GLOBAL ID: 200901092601480336
researchmap Member ID: 1000302907

External link: http://www.phoenix.ac.jp

Research Interests

Research Areas

Research History

1974 - 1975

Diichi College of Pharmaceutical Sciences Research Assistant
1974 - 1975

Daiichi University, College of Pharmaceutical Sciences
1975 - 1999

Miyazaki Medical College Research Assistant
1975 - 1999

Miyazaki Medical College
1985 - 1986

Southern Illinois University Visiting Assistant Professor
1985 - 1986

南イリノイ大学医学部客員助教授
1990 - 1990

University of Texas Visiting Assistant Professor
1990 - 1990

テキサス大学客員助教授
- 1999

1889-1999 宮崎医科大学兼任講師
1999 - 2003

School of Health Science, Kyushu University of Health and Welfare
2003

- 九州保健福祉大学薬学部教授
2003 - 2010

Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Sojo University
2006 - 2010

Faculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Sojo University
Apr, 2010 - Mar, 2020

Vice president
Apr, 2019 - Mar, 2022

九州保健福祉大学/保健科学部/学科長

Education

Committee Memberships

Jan, 2008 - Present

学校法人順正学園評議員
Mar, 1988 - Present

学術評議員, 日本薬理学会
Apr, 2011 - Mar, 2022

延岡市国民健康保険運営協議会委員
Feb, 2011 - Mar, 2022

宮崎県ジェネリック医薬品安全使用促進協議会会長
Apr, 2007 - Mar, 2022

宮崎県衛生環境研究所調査研究評価員委員
Apr, 2010 - Mar, 2012

日本脈管作働物質学会評議員
Sep, 2009 - Mar, 2012

「ふるさと雇用再生特別基金事業（チョウザメ・ブランド化事業）」に係る実行委員会委員
Aug, 2005 - Mar, 2011

都市エリア産学官連携促進事業における「共同研究推進会議」委員
Feb, 2006 - Mar, 2010

日本薬学会代議員
Apr, 2008 - Mar, 2009

日本薬学会九州支部支部長
Apr, 2007 - Mar, 2009

日本薬学会九州支部副支部長
Apr, 2007 - Mar, 2009

日本薬剤師会学術大会大会副委員長
Apr, 2001 - Mar, 2003

延岡市国民健康保険運営協議会委員

Papers

Brazilian propolis (AF-08) inhibits collagen-induced platelet aggregation without affecting blood coagulation

Chihiro Sugita, Atsushi Yamashita, Shigetoshi Tsutsumi, Hisahiro Kai, Tohru Sonoda, Hiroki Yoshida, Ryuichi Yamamoto, Yujiro Asada, Masahiko Kurokawa

Journal of Natural Medicines, 75(4) 975-984, Sep, 2021
Effects of M-1, a major metabolite of sarpogrelate, on 5-HT-induced constriction of isolated human internal thoracic artery

Naoko Tanaka-Totoribe, Muneaki Hidaka, Shuji Gamoh, Atsuko Yokota, Eisaku Nakamura, Masachika Kuwabara, Jun Tsunezumi, Ryuichi Yamamoto

Biol. Pharm. Bull., 43(12) 1979-1982, Dec, 2020 Peer-reviewedCorresponding author
Differences in the response to periarterial nerve stimulation or exogenous noradrenaline infusion in the mesenteric vascular bed with the intestinal tract harvested from commonly used rat models of hypertension

Shuji Gamoh, Tatsuo Shiba, Donald J. DiPette, Ryuichi Yamamoto

Clinical and Experimental Pharmacology and Physiology, 46(5) 427-434, May, 2019 Peer-reviewed
Diabetes Mellitus Induces Hyperreactivity of 5-Hydroxytryptamine (5-HT)-Induced Constriction in Human Internal Thoracic Artery and Is Associated with Increase in the Membrane Protein Level of 5-HT_2A Receptor.

Shiba T, Yokota A, Gamoh S, Tanaka-Totoribe N, Kuwabara M, Nakamura E, Hayase T, Nakamura K, Yamamoto R

Biological & pharmaceutical bulletin, 41(5) 820-823, May, 2018 Peer-reviewed
Angiotensin II, as well as 5-hydroxytriptamine, is a potent vasospasm inducer of saphenous vein graft for coronary artery bypass grafting in patients with diabetes mellitus

Yokota, A, Gamoh, S, Tanaka-Totoribe, N, Nakamura, K, Yamamoto, R

Biochemistry and Biophysics Reports, 6 82-87, Jun, 2016 Peer-reviewed
Water-soluble jack-knife prawn extract inhibits 5-hydroxytryptamine-induced vasoconstriction and platelet aggregation in humans.

Shuji Gamoh, Tasuku Kanai, Naoko Tanaka-Totoribe, Masamichi Ohkura, Masachika Kuwabara, Eisaku Nakamura, Atsuko Yokota, Tetsuo Yamasaki, Akiko Watanabe, Masahiro Hayashi …

Food & function, 6(2) 444-9, Feb, 2015 Peer-reviewed
Antiviral activity of diarylheptanoid stereoisomers against respiratory syncytial virus in vitro and in vivo

Katsuhiko Konno, Motofumi Miura, Masaharu Toriyama, Shigeyasu Motohashi, Rie Sawamura, Wataru Watanabe, Hiroki Yoshida, Masahiko Kato, Ryuichi Yamamoto, Ken Yasukawa …

Journal of Natural Medicines, 67(4) 773-781, Oct, 2013 Peer-reviewed
5-hydroxytryptamine receptors as targets for drug therapies of vascular-related diseases

Shuji Gamoh, Hiroaki Hisa, Ryuichi Yamamoto

Biological and Pharmaceutical Bulletin, 36(9) 1410-1415, Sep, 2013 Peer-reviewed
A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis

Nao Setoguchi, Norito Takamura, Ken-ichi Fujita, Kenji Ogata, Jin Tokunaga, Toyotaka Nishio, Etsuo Chosa, Kazuhiko Arimori, Keiichi Kawai, Ryuichi Yamamoto

Biopharmaceutics & Drug Disposition, 34(2) 125-136, Mar, 2013 Peer-reviewed
Mechanisms of 5-HT-induced enhanced vasoconstriction in coronary artery bypass graft harvested from patient with diabetes mellitus

TANAKA TOTORIBE Naoko, KANAI Tasuku, YAMAMOTO Ryuichi

Folia Pharmacologica Japonica, 141(2) 117-117, Feb 1, 2013
Insulin induces internalization of the plasma membrane 5- hydroxytryptamine 2A (5-HT 2A) receptor in the isolated human endothelium-denuded saphenous vein via the phosphatidylinositol 3-kinase pathway

Tasuku Kanai, Masachika Kuwabara, Naoko Tanaka-Totoribe, Eisaku Nakamura, Yasuko Matsuo, Shuji Gamoh, Akito Suzuki, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto

Journal of Pharmacological Sciences, 118(2) 178-185, 2012 Peer-reviewed
The defective protein level of myosin light chain phosphatase (MLCP) in the isolated saphenous vein, as a vascular conduit in coronary artery bypass grafting (CABG), harvested from patients with diabetes mellitus (DM)

Yasuko Matsuo, Masachika Kuwabara, Naoko Tanaka-Totoribe, Tasuku Kanai, Eisaku Nakamura, Shuji Gamoh, Akito Suzuki, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 412(2) 323-327, Aug, 2011 Peer-reviewed
Antiviral activities of diarylheptanoids isolated from Alpinia officinarum against respiratory syncytial virus, poliovirus, measles virus, and herpes simplex virus type 1 in vitro

Katsuhiko Konno, Rie Sawamura, Yi Sun, Ken Yasukawa, Tomomi Shimizu, Wataru Watanabe, Masahiko Kato, Ryuichi Yamamoto, Masahiko Kurokawa

Natural Product Communications, 6(12) 1881-1884, 2011 Peer-reviewed
Medical emergency education using emergency care simulators in the school of pharmaceutical sciences

Jin Tokunaga, Norito Takamura, Kenji Ogata, Hiroki Yoshida, Kazuhiro Totoribe, Masashi Nagata, Muneaki Hidaka, Toshikazu Matsuoka, Seiji Ono, Ryuichi Yamamoto …

Yakugaku Zasshi, 128(7) 1045-1055, Jul, 2008 Peer-reviewed
Development of a new treatment method in which restoration of tropicamide-induced mydriatic action is achieved in a short duration-Effect of washing with Krebs' or carbachol solution on the carbachol-induced contraction after treatment with tropicamide-:Effect of washing with Krebs' or carbachol solution on the carbachol-induced contraction after treatment with tropicamide

Okano Mayumi, Uchikawa Yoshikazu, Yamamoto Ryuichi

JOURNAL OF JAPANESE ASSOCIATION OF CERTIFIED ORTHOPTIST, 34 89-94, 2005 Peer-reviewed
Dysfunction of purinergic regulation of sympathetic neurotransmission in shr/ndmcr-cp (shr-cp) rat

Naoko Tanaka, Namie Nejime, Satomi Kagota, Yoko Kubota, Kazuki Nakamura, Masaru Kunitomo, Michio Hashimoto, Ryuichi Yamamoto, Kazumasa Shinozuka

Clinical and Experimental Pharmacology and Physiology, 31(2) S60-S61, Dec, 2004 Peer-reviewed
Mitogen-activated protein kinase, protein kinase C and cyclic AMP-dependent protein kinase differentially regulate the density of cell surface sodium channels.

T Yanagita, H Kobayashi, R Yamamoto, T Yuhi, H Yokoo, S Shiraishi, S Minami, Y Uezono, A Wada

CONTROL AND DISEASES OF SODIUM DEPENDENT TRANSPORT PROTEINS AND ION CHANNELS, 1208 185-186, 2000 Peer-reviewed
VASCULAR CONTRACTION IN PERFUSED CAROTID ARTERIES OF CHOLESTEROL-FED RABBITS

Y ASADA, R YAMAMOTO, K TAKASAKI, A SUMIYOSHI

ATHEROSCLEROSIS, 94(2-3) 233-239, Jun, 1992 Peer-reviewed
A new method for simultaneous measurement of endogenous noradrenaline release and vascular responsiveness in perfused rabbit carotid arteries in vitro

R. YAMAMOTO, Y. ASADA, A. SUMIYOSHI, K. TAKASAKI

Journal of Autonomic Pharmacology, 10(6) 313-322, 1990 Peer-reviewed
INVOLVEMENT OF PRESYNAPTIC α2‐ADRENORECEPTORS IN THE DEPRESSOR RESPONSE PRODUCED BY REPEATED ADMINISTRATION OF DEXTROMETHAMPHETAMINE

R. YAMAMOTO, K. TAKASAKI

Journal of Autonomic Pharmacology, 3(2) 79-88, 1983 Peer-reviewed

Misc.

103

Exendin-4, a glucagon-like peptide-1 analogue, inhibits 5-hydroxytryptamine-induced vasocontraction in the isolated human endothelium-denuded saphenous vein

Tasuku Kanai, Shuji Gamoh, Naoko Totoribe, Masachika Kuwabara, Eisaku Nakamura, Hiroaki Hisa, Ryuichi Yamamoto

JOURNAL OF PHARMACOLOGICAL SCIENCES, 121 204P-204P, 2013
Internalization of the plasma membrane 5-hydroxytryptamine2A (5-HT2A) receptor Induced by insulin in the isolated human endothelium-denuded saphenous vein

Tasuku Kanai, Masachika Kuwabara, Naoko Totoribe, Yasuko Matsuo, Eisaku Nakamura, Shuji Gamoh, Akito Suzuki, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto

JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 83P-83P, 2012
The decrease in the protein level of myosin light chain phosphatase in isolated saphenous vein harvested from patients with diabetes mellitus

Yasuko Matsuo, Masachika Kuwabara, Naoko Totoribe, Tasuku Kanai, Eisaku Nakamura, Shuji Gamoh, Akito Suzuki, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto

JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 202P-202P, 2012
Insulin-induced NO-independent vasodilation in the human endothelium-denuded saphenous vein

Tasuku Kanai, Yasuko Matuo, Naoko Tanaka, Masachika Kuwabara, Eisaku Nakamura, Hiroaki Hisa, Ryuichi Yamamoto

JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 107P-107P, 2011
共同研究につき担当部分抽出不可能８６）Relative Contributions of 5-Hydroxytryptamine (5-HT) Receptor Subtypes in 5-HT-induced Vasoconstriction of the Distended Human Saphenous Vein as a Coronary Artery Bypass Graft

Nakamura E, Tanaka N, Kuwabara M, Yamashita A, Matsuo Y, Kanai T, Onitsuka T, Asada Y, Hisa H, Yamamoto R

Biol. Pharm. Bull. Regular Article Pharmacology, 34(1) 82-86, Jan, 2011 Peer-reviewed
Relative contributions of Rho-kinase to the constrictions of human isolated internal thoracic artery and saphenous vein

Naoko Tanaka, Tasuku Kanai, Yasuko Matsuo, Masachika Kuwabara, Eisaku Nakamura, Kunihide Nakamura, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto

JOURNAL OF PHARMACOLOGICAL SCIENCES, 112 85P-85P, 2010
Inhibitory Effect of Lomerizine, a Prophylactic Drug for Migraines, on Serotonin-Induced Contraction of the Basilar Artery

Masakazu Ishii, Shunsuke Kobayashi, Masamichi Ohkura, Ryuichi Yamamoto, Shunichi Shimizu, Yuji Kiuchi

JOURNAL OF PHARMACOLOGICAL SCIENCES, 111(2) 221-225, Oct, 2009
Awareness of Hospital Pharmacists with Regard to Expanding the Professional Role of Pharmacists and Analysis of Factors Influencing This

TOKUNAGA Jin, KOINUMA Masayoshi, TAKAMURA Norito, OGATA Kenji, YOSHIDA Hiroki, YAMAMOTO Ryuichi, NAKAMURA Hitoshi

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 35(6) 417-422, Jun 10, 2009
薬学部における患者シミュレータを用いた体験型救命救急教育法の構築

徳永仁, 高村徳人, 緒方賢次, 吉田裕樹, 廣兼民徳, 牧原真治, 山岡章浩, 小野誠治, 山本隆一

日本薬学会年会要旨集, 129年会(4) 330-330, Mar, 2009
Survey on Attitudes of Hospital Pharmacists and Pharmacy Students Regarding Their Involvement in Taking Vital Signs and Medical Emergency Procedures

TOKUNAGA Jin, TAKAMURA Norito, OGATA Kenji, YOSHIDA Hiroki, YAMAMOTO Ryuichi

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 35(1) 50-56, Jan 10, 2009
Vascular responsiveness to 5-hydroxytryptamine in isolated human saphenous vein in diabetes mellitus

Naoko Tanaka, Eisaku Nakamura, Masachika Kuwabara, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto

JOURNAL OF PHARMACOLOGICAL SCIENCES, 109 74P-74P, 2009
Involvement of ARF1 in 5-hydroxytryptamine (5-HT)-induced internalization of the 5-HT2A receptor expressed in HEK293 cells

Ohkura M, Norota I, Tanaka N, Yamamoto R, Ishii K

J Pharmacol Sci Mtg Abst, 109 136P, 2009
Rho-Kinase, but not Protein Kinase C, is Involved in Generation of the Spontaneous Tone in the Resting Phase of the Isolated Pig Iris Sphincter Muscle

Mayumi Okano, Yoshikazu Uchikawa, Naoko Tanaka, Junpei Mutoh, Masamichi Ohkura, Hiroaki Hisa, Ryuichi Yamamoto

CURRENT EYE RESEARCH, 34(3) 177-183, 2009
Inclusion of Vital Sign Confirmation in Clinical Pharmacy Training at School of Pharmaceutical Sciences

TOKUNAGA Jin, TAKAMURA Norito, OGATA Kenji, YOSHIDA Hiroki, FURUYA Yumiko, TOTORIBE Kazuhiro, NAGATA Masashi, HIDAKA Muneaki, MATSUOKA Toshikazu, ONO Seiji …

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 34(9) 847-852, Sep 10, 2008
Both 5-hydroxytryptamine 5-HT(2A) and 5-HT(1B) receptors are involved in the vasoconstrictor response to 5-HT in the human isolated internal thoracic artery

Naoko Tanaka, Eisaku Nakamura, Masamichi Ohkura, Masachika Kuwabara, Atsushi Yamashita, Toshio Onitsuka, Yujiro Asada, Hiroaki Hisa, Ryuichi Yamamoto

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 35(7) 836-840, Jul, 2008
Serotonin induces vasoconstriction of smooth muscle cell-rich neointima through 5-hydroxytryptamine(2A) receptor in rabbit femoral arteries

K. Nishihira, A. Yamashita, N. Tanaka, S. Moriguchi-Goto, T. Imamura, T. Ishida, S. Kawashima, R. Yamamoto, K. Kitamura, Y. Asada

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 6(7) 1207-1214, Jul, 2008
Group Hospital Internship Conducted by Faculties of Pharmacy Schools

NAGATA Masashi, HIDAKA Muneaki, OHNO Rie, IWAKIRI Tomomi, OKUMURA Manabu, ARIMORI Kazuhiko, SUZUKI Akito, KAWACHI Akio, TOKUNAGA Jin, HIRAI Masami …

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences), 34(3) 256-262, Mar 10, 2008
ブタ瞳孔括約筋の静止張力発生機序

岡野真弓, 内川義和, 田中直子, 武藤純平, 大倉正道, 比佐博彰, 山本隆一

日本薬学会九州支部大会講演要旨集, 25th, 2008
摘出ブタ瞳孔括約筋の張力発生におよぼすRho-kinaseの役割

岡野真弓, 内川義和, 田中直子, 武藤純平, 大倉正道, 比佐博彰, 山本隆一

日本薬理学雑誌, 131(3), 2008
摘出ブタ瞳孔括約筋におけるRho-kinaseおよびProtein kinase Cの緊張調節への関与

田中直子, 岡野真弓, 内川義和, 武藤純平, 大倉正道, 比佐博彰, 山本隆一

日本薬学会年会要旨集, 128th(3), 2008

Books and Other Publications

Teaching Experience

Apr, 2004 - Present

機能形態学
Apr, 2003 - Present

Pharmacology

Professional Memberships

Jan, 1973 - Present

日本薬学会
Jan, 1973 - Present

日本薬理学会
Dec, 2004 - Mar, 2020

日本バイオイメージング学会
Apr, 2001 - Mar, 2020

日本眼薬理学会
Jan, 1987 - Mar, 2020

日本脈管作働物質学会
Apr, 2010 - Mar, 2012

日本脈管作動物質学会評議員

Research Projects

Effect of insulin on platelet aggregation in coronary artery bypass grafting

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2022

Yamamoto Ryuichi
Study of the inhibitory effect of GLP-1 preparation on coronary artery bypass graft vasospasm in patients with diabetes mellitus

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2020

GAMOH Shuji
Molecular mechanism for enhanced constriction of coronary artery bypass graft in patients with diabetes mellitus

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2017

Yamamoto Ryuichi
Is diabetes mellitus (DM) a high risk factor for coronary artery bypass grafting?

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2010 - 2012

YAMAMOTO Ryuichi, GAMOH Shuji, KANAI Tasuku, MATSUO Yasuko
A new mechanism for the fine adjustment of pupil size : Relation with endogenous peptide

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2001 - 2002

YAMAMOTO Ryuichi, SAWADA Atsushi, ASADA Yujiro, NAO-I Nobuhisa, OKANO Mayumi
Physiological function and gene expression of adremnomedullinfamily : adrenal medullary cells and isolated blood vessels

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Priority Areas, Japan Society for the Promotion of Science, 1998 - 2002

WADA Akihiko, YOKOO Hiroki, YANAGITA Toshihiko, KOBAYASHI Hideyuki, UEZONO Yasuhito, YAMAMOTO Ryuichi
Naチャネルの細胞膜発現調節:サブユニットmRNA変動と細胞内輸送・局在化機構

科学研究費助成事業, 奨励研究(A), 日本学術振興会, 1998 - 1999

柳田俊彦, 上園保仁, 小林英幸, 和田明彦, 山本隆一
Intracellular mechanisms regulating cell surface expression of Na channels : Na channel subunit mRNA levels and intracellular trafficking.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 1997 - 1998

WADA Akihiko, YANAGITA Toshihiko, YAMAMOTO Ryuichi, KOBAYASHI Hideyuki
Cカイネースによる細胞膜Naチャネルdown-regulationの細胞内機序

科学研究費助成事業, 基盤研究(C), 日本学術振興会, 1996 - 1996

和田明彦, 山本隆一, 小林英幸
虚血による脳GTP結合蛋白質とその遺伝子発現の変化

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1995 - 1995

小林英幸, 山本隆一
CカイネースによるNaチャネル発現の制御と細胞応答の修飾

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1995 - 1995

和田明彦, 山本隆一, 占部正信, 小林英幸
CカイネースおよびAカイネースによる転写調節蛋白の修飾とNaチャネル発現の制御

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1994 - 1994

和田明彦, 山本隆一, 占部正信
培養副腎髄質細胞における転写調節因子の変動とNaチャンネル発現の制御

科学研究費助成事業, 一般研究(C), 日本学術振興会, 1993 - 1993

和田明彦, 山本隆一, 占部正信
血管収縮反応における細胞内情報伝達の解明
動脈硬化における血管反応性変化の解明：ヒト摘出血管を用いた検討
Effect of adrenomedullin on eye function
Effect of nitric oxide on autonomic nervous system

Profile Information

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Research Areas

Research History

Education

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Papers

Misc.

Books and Other Publications

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