杉本八郎 (Hachiro Sugimoto) - マイポータル

基本情報

所属: 同志社大学脳科学研究科チェアプロフェッサー教授

J-GLOBAL ID: 200901069015546466
researchmap会員ID: 5000061331

MISC

Functional and molecular interactions between Rac1 and FE65

Pi-Lin Wang, Tetsuhiro Niidome, Toshiaki Kume, Akinori Akaike, Takeshi Kihara, Hachiro Sugimoto

NEUROREPORT 22(14) 716-720 2011年10月
アルツハイマー型認知症治療薬の開発～遥かなる創薬、ドネペジル塩酸塩の創製

杉本八郎

日本病院薬剤師会雑誌 47(8) 1012-1014. 2011年
Design, synthesis and evaluation of carbamate-modified (-)-N-1-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors

Jun Takahashi, Ichiro Hijikuro, Takeshi Kihara, Modachur G. Murugesh, Shinichiro Fuse, Yoshinori Tsumura, Akinori Akaike, Tetsuhiro Niidome, Takashi Takahashi, Hachiro Sugimoto

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(5) 1721-1723 2010年3月
Design, synthesis, evaluation and QSAR analysis of N-1-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors

Jun Takahashi, Ichiro Hijikuro, Takeshi Kihara, Modachur G. Murugesh, Shinichiro Fuse, Ryo Kunimoto, Yoshinori Tsumura, Akinori Akaike, Tetsuhiro Niidome, Yasushi Okuno …

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(5) 1718-1720 2010年3月
創薬研究から大学発ベンチャー起業

杉本八郎

バイオサイエンスとインダストリー 68(5) 357-360 2010年
AMPA reduces surface expression of NR1 through regulation of GSK3 beta

Takaaki Nishimoto, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

NEUROREPORT 20(2) 161-165 2009年1月
Epigallocatechin-3-gallate and curcumin suppress Aβ-induced BACE-1 up-regulation. 4.

杉本八郎

NeuroReport 19(13) 1329-1333 2008年8月
Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

NEUROREPORT 19(13) 1329-1333 2008年8月
Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

JOURNAL OF NEUROSCIENCE RESEARCH 86(8) 1836-1845 2008年6月
Multifunction of myricetin on Aβ: Neuroprotection via a conformational change of Aβ and reduction of Aβ via the interference of secretases.

杉本八郎

J. Neurosci. Res. 86(2) 368-377 2008年2月
Multifunction of myricetin on A beta: Neuroprotection via a conformational change of A beta and reduction of A beta via the interference of secretases

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

JOURNAL OF NEUROSCIENCE RESEARCH 86(2) 368-377 2008年2月
Flavonols and flavone as BACE-1 inhibitors: Structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features.

杉本八郎

Biochimica Biophysica Acta. 1780 819-825 2008年
Flavonols and flavone as BACE-1 inhibitors: Structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features.

Biochimica Biophysica Acta. 1780 819-825 2008年
Synthesis and pharmacological profile of serofendic acids A and B

Taro Terauchi, Naoki Asai, Takashi Doko, Ryota Taguchi, Osamu Takenaka, Hideki Sakurai, Masahiro Yonaga, Teiji Kimura, Akiharu Kajiwara, Tetsuhiro Niidome …

BIOORGANIC & MEDICINAL CHEMISTRY 15(22) 7098-7107 2007年11月

書籍等出版物

杉本八郎創薬への途

京都廣川書店 2010年
新しい薬をどう創るか

講談社ブルーバックス 2007年