杉本八郎 (Hachiro Sugimoto) - マイポータル

基本情報

所属: 同志社大学脳科学研究科チェアプロフェッサー教授

J-GLOBAL ID: 200901069015546466
researchmap会員ID: 5000061331

MISC

Functional and molecular interactions between Rac1 and FE65

Pi-Lin Wang, Tetsuhiro Niidome, Toshiaki Kume, Akinori Akaike, Takeshi Kihara, Hachiro Sugimoto

NEUROREPORT 22(14) 716-720 2011年10月
Functional and molecular interactions between Rac1 and FE65

Pi-Lin Wang, Tetsuhiro Niidome, Toshiaki Kume, Akinori Akaike, Takeshi Kihara, Hachiro Sugimoto

NEUROREPORT 22(14) 716-720 2011年10月
アルツハイマー型認知症治療薬の開発～遥かなる創薬、ドネペジル塩酸塩の創製

杉本八郎

日本病院薬剤師会雑誌 47(8) 1012-1014. 2011年
Design, synthesis and evaluation of carbamate-modified (-)-N-1-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors

Jun Takahashi, Ichiro Hijikuro, Takeshi Kihara, Modachur G. Murugesh, Shinichiro Fuse, Yoshinori Tsumura, Akinori Akaike, Tetsuhiro Niidome, Takashi Takahashi, Hachiro Sugimoto

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(5) 1721-1723 2010年3月
Design, synthesis, evaluation and QSAR analysis of N-1-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors

Jun Takahashi, Ichiro Hijikuro, Takeshi Kihara, Modachur G. Murugesh, Shinichiro Fuse, Ryo Kunimoto, Yoshinori Tsumura, Akinori Akaike, Tetsuhiro Niidome, Yasushi Okuno, Takashi Takahashi, Hachiro Sugimoto

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(5) 1718-1720 2010年3月
Design, synthesis and evaluation of carbamate-modified (-)-N-1-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors

Jun Takahashi, Ichiro Hijikuro, Takeshi Kihara, Modachur G. Murugesh, Shinichiro Fuse, Yoshinori Tsumura, Akinori Akaike, Tetsuhiro Niidome, Takashi Takahashi, Hachiro Sugimoto

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(5) 1721-1723 2010年3月
Design, synthesis, evaluation and QSAR analysis of N-1-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors

Jun Takahashi, Ichiro Hijikuro, Takeshi Kihara, Modachur G. Murugesh, Shinichiro Fuse, Ryo Kunimoto, Yoshinori Tsumura, Akinori Akaike, Tetsuhiro Niidome, Yasushi Okuno, Takashi Takahashi, Hachiro Sugimoto

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(5) 1718-1720 2010年3月
創薬研究から大学発ベンチャー起業

杉本八郎

バイオサイエンスとインダストリー 68(5) 357-360 2010年
AMPA reduces surface expression of NR1 through regulation of GSK3 beta

Takaaki Nishimoto, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

NEUROREPORT 20(2) 161-165 2009年1月
AMPA reduces surface expression of NR1 through regulation of GSK3 beta

Takaaki Nishimoto, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

NEUROREPORT 20(2) 161-165 2009年1月
Epigallocatechin-3-gallate and curcumin suppress Aβ-induced BACE-1 up-regulation. 4.

杉本八郎

NeuroReport 19(13) 1329-1333 2008年8月
Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

NEUROREPORT 19(13) 1329-1333 2008年8月
Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

JOURNAL OF NEUROSCIENCE RESEARCH 86(8) 1836-1845 2008年6月
Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

JOURNAL OF NEUROSCIENCE RESEARCH 86(8) 1836-1845 2008年6月
Multifunction of myricetin on Aβ: Neuroprotection via a conformational change of Aβ and reduction of Aβ via the interference of secretases.

杉本八郎

J. Neurosci. Res. 86(2) 368-377 2008年2月
Multifunction of myricetin on A beta: Neuroprotection via a conformational change of A beta and reduction of A beta via the interference of secretases

Yoshiari Shimmyo, Takeshi Kihara, Akinori Akaike, Tetsuhiro Niidome, Hachiro Sugimoto

JOURNAL OF NEUROSCIENCE RESEARCH 86(2) 368-377 2008年2月
Flavonols and flavone as BACE-1 inhibitors: Structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features.

杉本八郎

Biochimica Biophysica Acta. 1780 819-825 2008年
Flavonols and flavone as BACE-1 inhibitors: Structure-activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features.

Biochimica Biophysica Acta. 1780 819-825 2008年
Synthesis and pharmacological profile of serofendic acids A and B

Taro Terauchi, Naoki Asai, Takashi Doko, Ryota Taguchi, Osamu Takenaka, Hideki Sakurai, Masahiro Yonaga, Teiji Kimura, Akiharu Kajiwara, Tetsuhiro Niidome, Toshiaki Kume, Akinori Akaike, Hachiro Sugimoto

BIOORGANIC & MEDICINAL CHEMISTRY 15(22) 7098-7107 2007年11月
Synthesis and pharmacological profile of serofendic acids A and B

Taro Terauchi, Naoki Asai, Takashi Doko, Ryota Taguchi, Osamu Takenaka, Hideki Sakurai, Masahiro Yonaga, Teiji Kimura, Akiharu Kajiwara, Tetsuhiro Niidome, Toshiaki Kume, Akinori Akaike, Hachiro Sugimoto

BIOORGANIC & MEDICINAL CHEMISTRY 15(22) 7098-7107 2007年11月

書籍等出版物

杉本八郎創薬への途

京都廣川書店 2010年
新しい薬をどう創るか

講談社ブルーバックス 2007年