2002年1月21日
Proximal O,O′-capped calix[4]arenes with a disiloxane bridge as highly efficient synthetic intermediates for 1,2-dialkylation at the lower rim
Tetrahedron Letters
- ,
- ,
- ,
- ,
- ,
- 巻
- 43
- 号
- 4
- 開始ページ
- 621
- 終了ページ
- 625
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/S0040-4039(01)02202-X
Treatment of calix[4]arenes with 1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane using imidazole as a base yielded O,O′-bridged calixarenes in excellent yields, which were subsequently treated with an alkyl halide/base to give O″,O‴-dialkylated products in high yields. These were, in turn, amenable to fluoride-promoted quantitative desilylation, thus providing an efficient method for the net proximal dialkylation of calix[4]arenes at the lower rim. © 2002 Elsevier Science Ltd. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/S0040-4039(01)02202-X
- ISSN : 0040-4039
- CiNii Articles ID : 80012897906
- SCOPUS ID : 0037147921