原田伊知郎 (Harada Ichiro) - マイポータル

基本情報

所属: 社会医療法人社団蛍水会名戸ヶ谷病院附属名戸ヶ谷研究所メカノメディスン部門主任研究員

学位: 理学博士(東京工業大学)

J-GLOBAL ID: 200901073442468376
researchmap会員ID: 5000064958

研究キーワード

研究分野

ライフサイエンス / 生物物理学 /

経歴

東京工業大学大学院生命理工学研究科生体分子機能工学専攻大学院生命理工学研究科生体分子機能工学専攻助教

学歴

論文

Local cyclical compression modulates macrophage function in situ and alleviates immobilization-induced muscle atrophy.

Kumiko Saitou, Masakuni Tokunaga, Daisuke Yoshino, Naoyoshi Sakitani, Takahiro Maekawa, Youngjae Ryu, Motoshi Nagao, Hideki Nakamoto, Taku Saito, Noriaki Kawanishi, Katsuhiko Suzuki, Toru Ogata, Michiru Makuuchi, Atsushi Takashima, Keisuke Sawada, Shunsuke Kawamura, Koichi Nakazato, Karina Kouzaki, Ichiro Harada, Yoshinori Ichihara, Yasuhiro Sawada

Clinical science (London, England : 1979) 132(19) 2147-2161 2018年10月15日査読有り
Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression

Takahiro Ebata, Yasumasa Mitsui, Wataru Sugimoto, Miho Maeda, Keigo Araki, Hiroaki Machiyama, Ichiro Harada, Yasuhiro Sawada, Hideaki Fujita, Hiroaki Hirata, Keiko Kawauchi

BIOMED RESEARCH INTERNATIONAL 2017 5158961 2017年査読有り
MEKK1-dependent phosphorylation of calponin-3 tunes cell contractility

Hiroaki Hirata, Wei-Chi Ku, Ai Kia Yip, Chaitanya Prashant Ursekar, Keiko Kawauchi, Amrita Roy, Alvin Kunyao Guo, Sri Ram Krishna Vedula, Ichiro Harada, Keng-Hwee Chiam, Yasushi Ishihama, Chwee Teck Lim, Yasuhiro Sawada, Masahiro Sokabe

JOURNAL OF CELL SCIENCE 129(19) 3574-3582 2016年10月査読有り
Activation of Yes-Associated Protein in Low-Grade Meningiomas Is Regulated by Merlin, Cell Density, and Extracellular Matrix Stiffness

Kuniaki Tanahashi, Atsushi Natsume, Fumiharu Ohka, Kazuya Motomura, Adiljan Alim, Ichidai Tanaka, Takeshi Senga, Ichiro Harada, Ryuichi Fukuyama, Naoyuki Sumiyoshi, Yoshitaka Sekido, Toshihiko Wakabayashi

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 74(7) 704-709 2015年7月査読有り
The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix.

Yamashita H, Ichikawa T, Matsuyama D, Kimura Y, Ueda K, Craig SW, Harada I, Kioka N

Journal of cell science 127(9) 1875-1886 2014年5月査読有り
Coating extracellular matrix proteins on a (3-aminopropyl)triethoxysilane-treated glass substrate for improved cell culture

Hiro-taka Masuda, Seiichiro Ishihara, Ichiro Harada, Takeomi Mizutani, Masayori Ishikawa, Kazushige Kawabata, Hisashi Haga

BIOTECHNIQUES 56(4) 172-179 2014年4月査読有り
Dynamic chemotactic response of fibroblasts to local stimulation using EGF-immobilized microbeads

Fumihiro Aratsu, Ichiro Harada, Soichiro Yoshimura, Chong-Su Cho, Toshihiro Akaike, Yoh-ichi Tagawa

BIOMATERIALS 35(8) 2471-2476 2014年3月査読有り
Design and Construction of an Equibiaxial Cell Stretching System That Is Improved for Biochemical Analysis

Chaitanya Prashant Ursekar, Soo-Kng Teo, Hiroaki Hirata, Ichiro Harada, Keng-Hwee Chiam, Yasuhiro Sawada

PLOS ONE 9(3) e90665 2014年3月査読有り
p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion

Shota Yamauchi, Yan Yan Hou, Alvin Kunyao Guo, Hiroaki Hirata, Wataru Nakajima, Ai Kia Yip, Cheng-han Yu, Ichiro Harada, Keng-Hwee Chiam, Yasuhiro Sawada, Nobuyuki Tanaka, Keiko Kawauchi

JOURNAL OF CELL BIOLOGY 204(7) 1191-1207 2014年3月査読有り
Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions.

Ishihara S, Yasuda M, Harada I, Mizutani T, Kawabata K, Haga H

Experimental cell research 319(19) 2916-2927 2013年11月査読有り
Cellular Response to Substrate Rigidity Is Governed by Either Stress or Strain

Ai Kia Yip, Katsuhiko Iwasaki, Chaitanya Ursekar, Hiroaki Machiyama, Mayur Saxena, Huiling Chen, Ichiro Harada, Keng-Hwee Chiam, Yasuhiro Sawada

BIOPHYSICAL JOURNAL 104(1) 19-29 2013年1月査読有り
[Space flight/bedrest immobilization and bone. Mechanical stress : a double-edged sword to osteoarthritis].

Hiroyuki Matsui, Ichiro Harada, Muneaki Ishijima, Yasuhiro Sawada

Clinical calcium 22(12) 1855-62 2012年12月査読有り
Dual Inhibition of Src and GSK3 Maintains Mouse Embryonic Stem Cells, Whose Differentiation is Mechanically Regulated by Src Signaling

Takeshi Shimizu, Jun Ueda, Jolene Caifeng Ho, Katsuhiko Iwasaki, Lorenz Poellinger, Ichiro Harada, Yasuhiro Sawada

STEM CELLS 30(7) 1394-1404 2012年7月査読有り
Src, p130Cas, and Mechanotransduction in Cancer Cells.

Hiroyuki Matsui, Ichiro Harada, Yasuhiro Sawada

Genes & cancer 3(5-6) 394-401 2012年5月査読有り
Local Mechanical Stimulation of Mardin-Darby Canine Kidney Cell Sheets on Temperature-Responsive Hydrogel

Ichiro Harada, Shunpei Yanagisawa, Katsuhiko Iwasaki, Chong-Su Cho, Toshihiro Akaike

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 13(1) 1095-1108 2012年1月査読有り
Direct Detection of Cellular Adaptation to Local Cyclic Stretching at the Single Cell Level by Atomic Force Microscopy

Takahiro Watanabe-Nakayama, Shin-ichi Machida, Ichiro Harada, Hiroshi Sekiguchi, Rehana Afrin, Atsushi Ikai

BIOPHYSICAL JOURNAL 100(3) 564-572 2011年2月査読有り
Direct manipulation of intracellular stress fibres using a hook-shaped AFM probe

Shinichi Machida, Takahiro Watanabe-Nakayama, Ichiro Harada, Rehana Afrin, Tomonobu Nakayama, Atsushi Ikai

NANOTECHNOLOGY 21(38) 385102 2010年9月査読有り
Regulation of cellular morphology using temperature-responsive hydrogel for integrin-mediated mechanical force stimulation

Kazumasa Yamaki, Ichiro Harada, Mitsuaki Goto, Chong-Su Cho, Toshihiro Akaike

BIOMATERIALS 30(7) 1421-1427 2009年3月査読有り
Embryonic undifferentiated cells show scattering activity on a surface coated with immobilized E-cadherin

Masato Nagaoka, Hirohiko Ise, Ichiro Harada, Uichi Koshimizu, Atsushi Maruyama, Toshihiro Akaike

JOURNAL OF CELLULAR BIOCHEMISTRY 103(1) 296-310 2008年1月査読有り
Dramatic effect of Mg2+ on transfecting mammalian cells by DNA/calcium phosphate precipitates

EH Chowdhury, K Megumi, Harada, I, AK Kundu, T Akaike

ANALYTICAL BIOCHEMISTRY 328(1) 96-97 2004年5月査読有り

MISC

A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system

Ichiro Harada, Sung-Gon Kim, Chong Su Cho, Hisashi Kurosawa, Toshihiro Akaike

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 80A(1) 123-130 2007年1月
A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system

Ichiro Harada, Sung-Gon Kim, Chong Su Cho, Hisashi Kurosawa, Toshihiro Akaike

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 80A(1) 123-130 2007年1月
Galactose-carrying polymers as extracellular matrices for liver tissue engineering

CS Cho, SJ Seo, IK Park, SH Kim, TH Kim, T Hoshiba, Harada, I, T Akaike

BIOMATERIALS 27(4) 576-585 2006年2月
Galactose-carrying polymers as extracellular matrices for liver tissue engineering

CS Cho, SJ Seo, IK Park, SH Kim, TH Kim, T Hoshiba, Harada, I, T Akaike

BIOMATERIALS 27(4) 576-585 2006年2月
Fabrication of Elastic Substrates for Tissue Engineering by Two-Photon Initiated Polymerization

Kimura T, Watanabe, T, Totani, K, Oguni A, Harada I, Akaike T

Nonlinear Optics, Quantum Optics. 34 203 2006年
蛍光共鳴エネルギー移動（FRET）法による生体分子相互作用の可視化技術

原田伊知郎

生物工学 85(8) 331 2006年
Fabrication of Elastic Substrates for Tissue Engineering by Two-Photon Initiated Polymerization

Kimura T, Watanabe, T, Totani, K, Oguni A, Harada I, Akaike T

Nonlinear Optics, Quantum Optics. 34 203 2006年
Extracellular matrices as elastic scaffold and mechanical interaction

Harada I Akaike T

Biol Sci Space. 18(3) 120 2004年
Extracellular matrices as elastic scaffold and mechanical interaction

Harada I Akaike T

Biol Sci Space. 18(3) 120 2004年
Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment

IK Park, J Yang, HJ Jeong, HS Bom, Harada, I, T Akaike, S Kim, CS Cho

BIOMATERIALS 24(13) 2331-2337 2003年6月
Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment

IK Park, J Yang, HJ Jeong, HS Bom, Harada, I, T Akaike, S Kim, CS Cho

BIOMATERIALS 24(13) 2331-2337 2003年6月
Kinetics of volume phase transition in poly(N-isopropylacrylamide) gels

T Okajima, Harada, I, K Nishio, S Hirotsu

JOURNAL OF CHEMICAL PHYSICS 116(20) 9068-9077 2002年5月
Kinetics of volume phase transition in poly(N-isopropylacrylamide) gels

T Okajima, Harada, I, K Nishio, S Hirotsu

JOURNAL OF CHEMICAL PHYSICS 116(20) 9068-9077 2002年5月
Control of Spatially Periodic Patterns of Cell Aggregation on Soft ECM Substrata: Experiment Verification of Mechanochemical Model

Ichiro Harada

European Cell and Materials 2 54 2001年
Control of Spatially Periodic Patterns of Cell Aggregation on Soft ECM Substrata: Experiment Verification of Mechanochemical Model

Ichiro Harada

European Cell and Materials 2 54 2001年
Discontinuous Crossover between Fast and Slow Kinetics at the Volume Phase Transition in Poly-N-isopropylacrylamide

Ichiro Harada

Japananese Journal of Applied Physics 39(8B) L875-L877 2000年
Discontinuous Crossover between Fast and Slow Kinetics at the Volume Phase Transition in Poly-N-isopropylacrylamide

Ichiro Harada

Japananese Journal of Applied Physics 39(8B) L875-L877 2000年

書籍等出版物

「“ファイバー”スーパーバイオミメティックス～近未来の新技術創成～」

エヌ・ティー・エス出版 2006年
インテリジェントバイオマテリアル -細胞運動制御をめざす高分子ゲルの設計-

シーエムシー出版 2003年

原田伊知郎

基本情報

研究キーワード

研究分野

経歴

学歴

論文

MISC

書籍等出版物

所属学協会

メニュー