UENO TAKAHIRO

Profile Information

Degree: 医学博士(日本大学)

Researcher number: 40386008
J-GLOBAL ID: 200901077524872588
researchmap Member ID: 5000081006

Research Areas

Research History

Nov, 2008

Associate Professor, Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Nihon University School of Medicine
May, 2007 - Oct, 2008

Assistant Professor, Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Nihon University School of Medicine
Jun, 2008

Itabashi Hospital (School of Medicine), Nihon University
Dec, 2004 - May, 2008

日本大学附属板橋病院腎臓内分泌内科病棟医長
May, 2004 - Apr, 2008

日本大学医学部内科学講座腎臓内分泌内科助手
Mar, 2002 - Apr, 2004

日本大学医学部第二内科助手
May, 1998 - Feb, 2002

Postdoctoral fellow of the Labo of Molecular Medicine, CHUM-Hotel-Dieu, Montreal University, Canada
Apr, 1991 - Apr, 1998

日本大学医学部第二内科助手
Associate Professor, Nihon University School of Medicine, Department of Medicine

Education

- 1991

Nihon University Gradutae School of Medicine

Committee Memberships

Awards

May, 2012

日本大学医師会学術奨励賞, メタボリックシンドロームモデルにおける内臓脂肪高発現遺伝子の解析
Dec, 2007

地域医学研究基金奨励賞
Oct, 2005

第42回日本臨床生理学会最優秀演題賞
Jun, 2003

地域医学研究基金奨励賞
Apr, 2003

日本大学医学部同窓会60周年記念医学奨励賞

Papers

E-selectin gene and essential hypertension

Takahiro Ueno

HYPERTENSION RESEARCH, 35(4) 380-380, Apr, 2012 Peer-reviewed
Role of Complement 3a in the Synthetic Phenotype and Angiotensin II-Production in Vascular Smooth Muscle Cells From Spontaneously Hypertensive Rats

Ying Han, Noboru Fukuda, Takahiro Ueno, Morito Endo, Kazuya Ikeda, Zhou Xueli, Taro Matsumoto, Masayoshi Soma, Koichi Matsumoto

AMERICAN JOURNAL OF HYPERTENSION, 25(3) 284-289, Mar, 2012 Peer-reviewed
Quantitation of Pyrrole-Imidazole Polyamide in Rat Plasma by High-Performance Liquid Chromatography Coupled with UV Detection

Tomonori Kamei, Takahiko Aoyama, Chihiro Tanaka, Takafumi Nagashima, Yukio Aoyama, Hiroyuki Hayashi, Hiroki Nagase, Takahiro Ueno, Noboru Fukuda, Yoshiaki Matsumoto

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 715928, 2012 Peer-reviewed
Obesity alters the expression profile of clock genes in peripheral blood mononuclear cells.

Tahira K, Ueno T, Fukuda N, Aoyama T, Tsunemi A, Matsumoto S, Nagura C, Matsumoto T, Soma M, Shimba S …

Archives of Medical Science, 6 933-940, Dec 1, 2011 Peer-reviewed
Anderson's disease/chylomicron retention disease in a Japanese patient with uniparental disomy 7 and a normal SAR1B gene protein coding sequence

Tomoo Okada, Michio Miyashita, Junji Fukuhara, Masahiko Sugitani, Takahiro Ueno, Marie-Elisabeth Samson-Bouma, Lawrence P. Aggerbeck

ORPHANET JOURNAL OF RARE DISEASES, 6(78) 1-9, Nov, 2011 Peer-reviewed
Development of a novel gene silencer pyrrole-imidazole polyamide targeting human connective tissue growth factor

Jian-Xin Wan, Noboru Fukuda, Takahiro Ueno, Takayoshi Watanabe, Hiroyuki Matsuda, Kosuke Saito, Hiroki Nagase, Yoshiaki Matsumoto, Koichi Matsumoto

Biological and Pharmaceutical Bulletin, 34(10) 1572-1577, Oct, 2011 Peer-reviewed
Protective effects of statin on cardiac fibrosis and apoptosis in adrenomedullin-knockout mice treated with angiotensin II and high salt loading

Chii Yamamoto, Noboru Fukuda, Medet Jumabay, Kosuke Saito, Taro Matsumoto, Takahiro Ueno, Masayoshi Soma, Koichi Matsumoto, Tatsuo Shimosawa

HYPERTENSION RESEARCH, 34(3) 348-353, Mar, 2011 Peer-reviewed
Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-beta 1 promoter

Hiroyuki Matsuda, Noboru Fukuda, Takahiro Ueno, Mayumi Katakawa, Xiaofei Wang, Takayoshi Watanabe, Sei-Ichi Matsui, Takahiko Aoyama, Kosuke Saito, Toshikazu Bando …

KIDNEY INTERNATIONAL, 79(1) 46-56, Jan, 2011 Peer-reviewed
Treatment with valsartan stimulates endothelial progenitor cells and renal label-retaining cells in hypertensive rats

Yoshinori Yoshida, Noboru Fukuda, Akito Maeshima, Chii Yamamoto, Taro Matsumoto, Takahiro Ueno, Yoshihisa Nojima, Koichi Matsumoto, Masayoshi Soma

JOURNAL OF HYPERTENSION, 29(1) 91-101, Jan, 2011 Peer-reviewed
Zinc-finger transcriptional factor Sall1 induces angiogenesis by activation of the gene for VEGF-A

Chii Yamamoto, Noboru Fukuda, Taro Matsumoto, Terumi Higuchi, Takahiro Ueno, Koichi Matsumoto

HYPERTENSION RESEARCH, 33(2) 143-148, Feb, 2010 Peer-reviewed
Appropriate doses of Granulocyte-Colony Stimulating Factor reduced atherosclerotic plaque formation and increased plaque stability in cholesterol-fed rabbits.

Matsumoto T, Watanabe H, Ueno T, Tsunemi A, Hatano B, Kusumi Y, Mitsumata M, Fukuda N, Matsumoto K, Saito S …

Journal of Atherosclerosis and thrombosis, 17(1) 84-96, Jan 1, 2010 Peer-reviewed
Pharmacokinetic/pharmacodynamic modeling and simulation of rosuvastatin using an extension of the indirect response model by incorporating a circadian Rhythm

Takahiko Aoyama, Takayuki Omori, Satoshi Watabe, Akemi Shioya, Takahiro Ueno, Noboru Fukuda, Yoshiaki Matsumoto

Biological and Pharmaceutical Bulletin, 33(6) 1082-1087, 2010 Peer-reviewed
Acute anterior myocardial infarction superimposing double left anterior descending artery: Depiction at whole-heart coronary magnetic resonance angiography whole-heart coronary magnetic resonance angiography.

Matsumoto N, SatoY, Kunimasa T, Tani S, Kasama S, Suzuki Y, Chiku M, Ueno T, SaitoS, Hirayama A …

International Journal of Cardiology, 143(3) e39-41, Jan 1, 2010 Peer-reviewed
トータル血管マネージメント、血管構造から見たリスク因子の違いとその管理.

日本医事新報, 4442 52-55, Jan 1, 2010
Ubiquitin-positive foam cells are identified in the aortic and mitral valves with atherosclerotic involvement.

Yamada T, Satoh S, Sueyoshi S, Mitsumata M, Matsumoto T, Ueno T, Uehara K, Mizutani T

Journal of Atherosclerosis and thrombosis, 16(4) 472-479, Aug, 2009 Peer-reviewed
Effects of atrovastatin on angiogenesis in hindlimb ischemia and endothelial progenitor cell formation in rats.

Matsumura M, Fukuda N, Kobayashi N, Takasaka A, Matsumoto T, Yao EH, Ueno T, Negishi N

ournal of Atherosclerosis and thrombosis, 16(4) 316-326, Aug, 2009 Peer-reviewed
Influence of genetic polymorphisms of oxidative stress related genes and smoking on plasma MDA-LDL, soluble CD40 ligand, E-selectin and soluble ICAM1 levels in patients with coronary artery disease.

Medical Science Monitor, 15(7) CR341-348, Jul, 2009
Pharmakokinetic modeling and prediction of plasma pyrrole-imidazole polyamide concentration in rats using simultaneous urinary and biliary excretion data.

Biological & Pharmaceutical Bulletin, 32(5) 921-927, May, 2009
Determination of pyrrole-imidazole polyamide in rat plasma by liquid chromatography-tandem mass spectrometry

Takashi Nagashima, Takahiko Aoyama, Akiko Fukasawa, Satoshi Watabe, Noboru Fukuda, Takahiro Ueno, Hiroshi Sugiyama, Hiroki Nagase, Yoshiaki Matsumoto

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 877(11-12) 1070-1076, Apr, 2009
Pharmacokinetics of Pyrrole-imidazole Polyamides after Intravenous Administration in Rat

Akiko Fukasawa, Takahiko Aoyama, Takashi Nagashima, Noboru Fukuda, Takahiro Ueno, Hiroshi Sugiyama, Hiroki Nagase, Yoshiaki Matsumoto

BIOPHARMACEUTICS & DRUG DISPOSITION, 30(2) 81-89, Mar, 2009 Peer-reviewed

Presentations

367

Effect of Ezetimibe on endothelial function and inflammation markers.

Kazunobu Tahira, Takahiro Ueno, Chinami Nagura, Maki Kitai, Yoshinari Hatanaka, Akiko Tsunemi, Taro Matsumoto, Noboru Fukuda, Masayoshi Soma

第44回日本動脈硬化学会, Jul, 2012
Modification of insulin signaling to glucose transport in differentiated 3T3-L1 cells by the pharmacological inhibition of heat shock protein 70.

Takahiro Ueno, Akiko Tsunemi, Kazunobu Tahira, Taro Matsumoto, Noboru Fukuda, Masayoshi Soma

第44回日本動脈硬化学会, Jul, 2012
Pharmacological inhibition of heat shock protein 70 induced actin fiber conformational change through cofilin phosphorylation in 3T3-L1 cells during adipogenesis.

Takahiro Ueno, Akiko Tsunemi, Kazunobu Tahira, Taro Matsumoto, Noboru Fukuda, Masayoshi Soma

第44回日本動脈硬化学会, Jul, 2012
補体C3は腎尿細管上皮を間葉化しレニンを産生する.

Xueli Zhou, 福田昇, 上野高浩, 遠藤守人, 松本紘一, 相馬正義

第85回日本内分泌学会, Jun, 2012
補体C3は腎尿細管で上皮間葉化（EMT）を起こし腎内レニン・アンギオテンシン(RA)系を亢進する.

Xueli Zhou, 福田昇, 上野高浩, 遠藤守人, 松本紘一, 相馬正義

第55回日本腎臓学会, Jun, 2012
脱分化脂肪細胞（DFAT）移植による単クローン抗体1-22-3誘発腎炎の改善.

丸山高史, 福田昇, 渡辺めぐみ, 上野高浩, 松本太郎, 山元智衣, 遠藤守人, 松本紘一, 相馬正義, 河内裕

第55回日本腎臓学会, Jun, 2012
補体C3は腎尿細管上皮を間葉化し腎内レニン・アンギオテンシン系を亢進する.

Xueli Zhou, 福田昇, 上野高浩, 遠藤守人, 松本紘一, 相馬正義

第41回日本心脈管作動物質学会, Feb, 2012
腎尿細管での上皮間葉化（EMT）現象による補体C3を介したレニン分泌の検討.

Xueli Zhou, 福田昇, 上野高浩, 遠藤守人, 松本紘一, 相馬正義

第34回日本高血圧学会, Oct, 2011
LOX-1のMMPを介した大動脈瘤形成とLOX-1遺伝子制御薬PIポリアミドの効果.

高坂彩子, 福田昇, 上野高浩, 常見明子, 楠見嘉晃, 塩野元美, 澤村達也

第34回日本高血圧学会, Oct, 2011
Heat Shock Protein 70の脂肪細胞脂質蓄積過程における小胞体ストレスに対する影響.

上野高浩, 福田昇, 常見明子, 田平和宣, 松本太郎, 相馬正義

第34回日本高血圧学会, Oct, 2011
血管内皮前駆細胞（EPC）を活性化する抗酸化食生活習慣の調査臨床試験.

片川まゆみ, 福田昇, 常見明子, 上野高浩, 森真理, 家森幸男, 松本太郎, 相馬正義

第34回日本高血圧学会, Oct, 2011
血管内皮前駆細胞（EPC）を活性化する抗酸化食生活習慣の調査臨床試験.

片川まゆみ, 福田昇, 常見明子, 上野高浩, 森真理, 家森幸男, 松本太郎, 相馬正義

第33回日本臨床栄養学会総会, Oct, 2011
Ultrasonic textural changes of carotid intima-media complex in patients after Kawasaki disease: Comparison among patients with familial hypercholesterolemia, control subjects and model rats.

Noto N, Abe Y, Miyashita M, Okada T, Ueno T, Yamada T

第43回日本動脈硬化学会, Jul, 2011
Effect of eicosapentaenoic acid (EPA) on Per1 gene expression in H35 hepatoma cells.

Nagura C, Ueno T, Tahira K, Fukuda N, Tsunemi A, Matsumoto T, Soma M

第43回日本動脈硬化学会, Jul, 2011
Pharmacological inhibition of heat shock protein 70 reduced lipid accumulation in 3T3-L1 cells during adipogenesis.

Ueno T, Fukuda N, Tsunemi A, Matsumoto T, Tahira K, Nagura C, Soma M

第43回日本動脈硬化学会, Jul, 2011
Contribution of LOX-1 in the aortic aneurysm and effects of PI polyamide targeting LOX-1.

Takasaka A, Fukuda N, Ueno T, Tsunemi A, Kusumi Y, Orime Y, Shiono M, Sawamura T

第43回日本動脈硬化学会, Jul, 2011
Investigation and clinical study of anti-oxidative dietary custom to activate endotherial progenitor cell function in humans.

Katakawa M, Fukuda N, Tsunemi A, Ueno T, Mori M, Yamori Y, Matsumoto T, Soma M

第43回日本動脈硬化学会, Jul, 2011
自己再生細胞を活性化する抗老化食生活習慣の検討.

片川まゆみ, 福田昇, 上野高浩, 松本太郎, 相馬正義, 家森幸男

第40回日本心脈管作動物質学会, Feb, 2011
自己免疫性腎炎に対する新規遺伝子制御薬Fc受容体γ鎖PIポリアミドの開発.

梶原麻実子, 福田昇, 松田裕之, 上野高浩, 北井真貴, 松本宜明, 羅智靖, 相馬正義, 松本紘一

第１回腎不全研究会, Dec, 2010
高血圧症性血管および腎リモデリングにおける補体C3の役割.

池田和也, 上野高浩, 福田昇, 相馬正義, 遠藤守人, 山元智衣, 松本紘一

第33回日本高血圧学会, Oct, 2010

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