TAZAKI Hiroyuki

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Name
TAZAKI Hiroyuki
Affiliation
Nippon Veterinary and Life Science University
Section
Faculty of Veterinary Science, School of Veterinary Medicine
Job title
Professor

Published Papers

 
Serum bromine concentrations in horses in Japan
TAZAKI Hiroyuki
Journal of Veterinary Medical Science   80(8) 1228-1232   Aug 2018   [Refereed]
R. Akabane, T. Sato, A. Sakatani, Y. Miyagawa, H. Tazaki, N. Takemura
Journal of Veterinary Pharmacology and Therapeutics   41 457-462   Jun 2018
© 2018 John Wiley & Sons Ltd Basic information related to the pharmacokinetics of sildenafil in dogs is scarce. This study aimed to describe the pharmacokinetic properties of oral sildenafil and determine the effect of feeding and dose proportio...
Mariko Mochizuki, Noriyuki Hayakawa, Fumiko Minowa, Akihiro Saito, Katsumi Ishioka, Fukiko Ueda, Kimihiro Okubo, Hiroyuki Tazaki
Environmental Monitoring and Assessment   188(4) 6   Apr 2016
© 2016, Springer International Publishing Switzerland.In this study, iodine and thyroxin (T4) concentrations in the serum of 69 horses were investigated. Higher iodine concentrations were obtained from the horses housed in Chiba Prefecture. In con...
Satoshi Nozawa, Touko Sato, Kinya Katayama, Katsumi Ishioka, Toshinori Sako, Toshiro Arai, Hiroyuki Tazaki
Veterinary Journal   207 184-187   Jan 2016
© 2015 Elsevier Ltd.In dogs, hyperadrenocorticism (HAC) is associated with insulin resistance and diabetes does progress with HAC. There are significant differences in the transcriptomic and proteomic patterns of activated T cells, which parallel ...
Megumi Fujiwara, Nobuko Mori, Touko Sato, Hiroyuki Tazaki, Shingo Ishikawa, Ichiro Yamamoto, Toshiro Arai
BMC Veterinary Research   11(1)    Aug 2015
© 2015 Fujiwara et al.Background: Obesity and overweight have been frequently observed in dogs and cats in recent years as in humans. The compositions of fatty acids (FAs) in the accumulated lipids in tissues of obese animals may have important ro...
Fumihito Takahashi, Mariko Mochizuki, Takuya Yogo, Katsumi Ishioka, Norio Yumoto, Toshinori Sako, Fukiko Ueda, Masahiro Tagawa, Hiroyuki Tazaki
Journal of Veterinary Medical Science   76(4) 569-572   Jan 2014
To understand the effects of silicon (Si) in the urine with respect to the formation of urinary stones, the distribution of Si in urine was observed. Urine samples from cats with urolithiasis (n=10) and healthy cats (n=15) were used. The concentra...
Satoshi Nozawa, Satoshi Nozawa, Hitomi Oda, Ran Akiyama, Kaori Ueda, Kaori Saeki, Saori Shono, Natsuki Maruyama, Atsuki Murata, Hiroyuki Tazaki, Akihiro Mori, Yutaka Momota, Daigo Azakami, Toshinori Sako, Katsumi Ishioka
Journal of Veterinary Medical Science   76(8) 1177-1182   Jan 2014
© 2014 The Japanese Society of Veterinary Science.Hyperadrenocorticism (HAC) is a common endocrine disorder in dogs, in which excess glucocorticoid causes insulin resistance. Disturbance of insulin action may be caused by multiple factors, includi...
Megumi Fujiwara, Toko Sato, Hiroyuki Tazaki, Ichiro Yamamoto, Koh Kawasumi, Toshiro Arai
Asian Journal of Animal and Veterinary Advances   8(4) 639-646   Jul 2013
Hyperlipidemia refers to increase of triglyceride (TG) and/or total cholesterol (T-cho) in blood. Fatty Acids (FAs) have important roles in the lipid metabolism. The aim of this study was to determine the FA composition of plasma lipid fractions i...
Fumihito Takahashi, Mariko Mochizuki, Touko Sato, Kinya Katayama, Paul R. Kenyon, Stephen T. Morris, Peter D. Kemp, Takeyuki Ozawa, Fukiko Ueda, Hiroyuki Tazaki
Animal Science Journal   84(6) 496-501   Jun 2013
The establishment of a classification system for domestic animals on consumed feed stuff is thought to be important from both a hygiene and market point of view. We collected plasma samples of Romney lambs (Ovis aries) which were fed one of the fo...
K. Katayama, T. Sato, T. Arai, H. Amao, Y. Ohta, T. Ozawa, P. R. Kenyon, R. E. Hickson, H. Tazaki
Journal of Animal Physiology and Animal Nutrition   97(1) 119-125   Feb 2013
Simple liquid chromatography-mass spectrometry (LC-MS) was applied to non-targeted metabolic analyses to discover new metabolic markers in animal plasma. Principle component analysis (PCA) and partial least squares-discriminate analysis (PLS-DA) w...
Kinya Katayama, Masako Miyoshi, Kensuke Nabeta, Hiroyuki Tazaki
Phytochemistry Letters   5(4) 761-765   Dec 2012
The in vitro cultured liverwort Jungermannia subulata produces the unique molecule subulatin. In this study, we examined the incorporation of [1- 13C] and [1,2-13C2] glucose, [2-13C] arabinose, [2-13C] caffeic acid, and [1-13C] phenylalanine into ...
Yohei Miki, Akihiro Mori, Noriyuki Hayakawa, Tomoe Niki, Hitomi Oda, Kaori Saeki, Toko Sato, Hiroyuki Tazaki, Katsumi Ishioka, Toshiro Arai, Toshinori Sako
Journal of Veterinary Medical Science   73(9) 1117-1126   Sep 2011
1,5-anhydro-D-glucitol (1,5AG) is a pyranoid polyol compound found in human circulating blood. Myo-inositol (MI) is a stereoisomer of inositol and serves as a precursor of inositol phospholipids. 1,5AG and MI are filtered by the glomerulus and alm...
T. Sato, A. Toyoshima, T. Hiraki, Y. Ohta, K. Katayama, T. Arai, H. Tazaki
British Poultry Science   52(2) 273-277   Apr 2011
1. The objective of this study was to determine the effects of the gluconeogenesis inhibitor metformin on 21-d old chickens. The following parameters were measured in the liver and kidney: plasma glucose, plasma mannose, enzyme activities and mRNA...
J. S. Jeong, J. H. Lee, Y. Simizu, H. Tazaki, H. Itabashi, N. Kimura
Animal Feed Science and Technology   162(3-4) 144-148   Dec 2010
The objective of this study was to determine the effect of deoxynivalenol (DON) on in vitro rumen fermentation by assessing pH, ammonia-N, total gas, volatile fatty acid (VFA) production, and DON degradation under the context of two different carb...
A. Mori, T. Sato, T. Sato, P. Lee, M. Furuuchi, H. Tazaki, K. Katayama, H. Mizutani, T. Sako, T. Arai
Veterinary Research Communications   33(5) 439-451   Jan 2009
Circulating levels of monosaccharides can act as a reflection of systemic glucose/energy metabolism. Characteristic changes observed in these levels can be seen in patients with diabetes and other metabolic disorders. There have been a few reports...
T. Sako, A. Mori, P. Lee, T. Sato, H. Mizutani, T. Takahashi, Y. Kiyosawa, H. Tazaki, T. Arai
Veterinary Research Communications   33(5) 473-479   Jan 2009
Measurements of serum fructosamine, glycated hemoglobin, and glycated albumin (GA) complement serum glucose concentration for better management of diabetes mellitus (DM). Especially, the serum fructosamine test has long been used for diagnosing an...
T. Sato, T. Sato, S. Soeda, Y. Ohta, K. Katayama, T. Arai, H. Tazaki
British Poultry Science   49(6) 731-735   2009
The oral administration of glucose or dietary glucose reduces fasting plasma mannose concentrations in mammals. On the other hand, there have been no reports on plasma mannose levels in birds. We have analysed chicken plasma mannose and glucose by...
Y. Tanaka, A. Mori, H. Tazaki, S. Imai, J. Shiina, A. Kusaba, T. Ozawa, T. Yoshida, N. Kimura, T. Hayashi, P. R. Kenyon, H. Blair, T. Arai
Research in Veterinary Science   85(1) 17-21   Aug 2008
Plasma metabolite concentrations and activities of enzymes related to energy metabolism in plasma, peripheral leukocytes and liver of pregnant Romney ewes with restricted feeding were measured to assess those metabolites and enzymes as indicators ...
T. Sato, K. Katayama, T. Arai, T. Sako, H. Tazaki
Research in Veterinary Science   84(1) 26-29   Feb 2008
Serum mannose and glucose concentrations in dogs before and after eating a meal were determined simultaneously with a recently established HPLC method combined with a UV and fluorescence detection system of p-aminobenzoic acid ethyl ester (ABEE)-d...
A. Mori, P. R. Kenyon, N. Mori, I. Yamamoto, Y. Tanaka, N. Suzuki, H. Tazaki, T. Ozawa, T. Hayashi, R. E. Hickson, S. T. Morris, H. Blair, T. Arai
Veterinary Research Communications   32(2) 159-166   Feb 2008
Metabolite and immunoreactive insulin (IRI) concentrations, energy metabolism related enzymes activities and peripheral blood mononuclear cell (PBMC) populations were measured in blood of pregnant Angus heifers with differing liveweight change pro...
Kinya Katayama, Kazuko Shimazaki, Hiroyuki Tazaki, Yasuhiro Hasa, Masako Miyoshi, Hiroyuki Koshino, Tatsuo Furuki, Kensuke Nabeta
Bioscience, Biotechnology and Biochemistry   71(11) 2751-2758   Nov 2007
New clerodane-type diterpenes, designated as parvitexins A (1)-E (5), were isolated from the in vitro-cultured liverwort, Scapania parvitexta. These compounds were determined to be monoacetylated clerodane-type diterpenes based on spectroscopic ev...
Satoru Watanabe, Ken Hashimoto, Hiroyuki Tazaki, Yuzuri Iwamoto, Naoko Shinohara, Kazue Satoh, Hiroshi Sakagami
Food Science and Technology Research   13(4) 366-371   Nov 2007
Four phenolic compounds were isolated from Japanese butterbur (Petasites japonicus) by preparative RP-HPLC technique, and were identified as chlorogenic acid (CGA), fukinolic acid (FA), 3,5-dicaffeoyl quinic acid, and 3,4,5-tricaffeoyl quinic acid...
A. Mori, A. Mori, S. Urabe, S. Urabe, M. Asada, M. Asada, Y. Tanaka, Y. Tanaka, H. Tazaki, H. Tazaki, I. Yamamoto, I. Yamamoto, N. Kimura, N. Kimura, T. Ozawa, T. Ozawa, S. T. Morris, S. T. Morris, R. Hickson, R. Hickson, P. R. Kenyon, P. R. Kenyon, H. Blair, H. Blair, C. B. Choi, C. B. Choi, T. Arai, T. Arai
Journal of Veterinary Medicine Series A: Physiology Pathology Clinical Medicine   54(7) 342-345   Sep 2007
Concentrations of metabolites and immunoreactive insulin (IRI) and activities of enzymes related to energy metabolism were measured in plasma of Korean and Japanese beef cattle, which were raised by the indoor feeding system programmed to feed lar...
T. Sako, S. Urabe, A. Kusaba, N. Kimura, I. Yoshimura, H. Tazaki, S. Imai, K. Ono, T. Arai
Veterinary Research Communications   31(4) 413-417   May 2007
Yasuhiro Hasa, Hiroyuki Tazaki, Masao Ohnishi, Yuji Oda, Yuji Oda
Food Biotechnology   20(3) 263-274   Dec 2006
Potato pulp containing starch, cellulose, hemicellulose, and pectin is an agricultural by-product in the starch industry. Potato pulp was hydrolyzed by semiaerobic growth of the fungus Amylomyces rouxii, mixed with water, and filtrated to separate...
T. Arai, Y. Tanaka, S. Urabe, A. Kusaba, H. Tazaki, T. Ozawa, N. Kimura, K. K. Jung, K. Waragaya, T. Yuyama, Y. Haseba, S. Imai
Research in Veterinary Science   81(1) 19-23   Aug 2006
Plasma metabolite and immunoreactive insulin concentrations and activities of enzymes related to energy metabolism in peripheral leukocytes were measured in growing Holstein calves. A ratio of girth of abdomen divided by girth of thorax (A/T ratio...
Keita Yunoki, Keita Yunoki, Renaguli Musa, Renaguli Musa, Mikio Kinoshita, Hiroyuki Tazaki, Hiroyuki Tazaki, Yuji Oda, Masao Ohnishi, Masao Ohnishi
Bioscience, Biotechnology and Biochemistry   68(12) 2619-2622   Dec 2004
Higher alcohols with a carbon length ranging from 16 to 30 found in the lipophilic fraction from potato pulp were shown to be present as ferulate and in a free form, but not as wax. Thin-layer chromatography of the neutral lipids in potato pulp in...
Shoji Hattori, Chiami Kawaharada, Hiroyuki Tazaki, Hiroyuki Tazaki, Takane Fujimori, Koji Kimura, Masao Ohnishi, Kensuke Nabeta
Bioscience, Biotechnology and Biochemistry   68(12) 2656-2659   Dec 2004
Thermally decomposed products of (±)-linalyl β-D-glucoside were analyzed by GC and GC/MS. 2,6-Dimethyl-2,6-octadienes produced by mild pyrolysis of linalyl β-D-glucopyranoside under a vacuum were detected and characterized by MS and NMR spectrosco...
Yasuhiro Hasa, Hiroyuki Tazaki, Hiroyuki Tazaki, Hiroyuki Tazaki
Bioscience, Biotechnology and Biochemistry   68(10) 2212-2214   Oct 2004
The biosynthesis of fukinolic acid, which had been isolated from the Japanese fuki vegetable, Petasites japonicus, was investigated by feeding selected 13C-labeled compounds to axenic cultures of P. japonicus. [1,2-13C2] sodium acetate and [1-13C]...
Hiroyuki Tazaki, Jun Kawabata, Takashi Fujita
Bioscience, Biotechnology and Biochemistry   67(5) 1185-1187   May 2003
The novel Diels-Alder adduct, dicaffeoyl quinone as its hydrate, was formed from the oxidation of 3,4-dihydroxycinnamic acid (caffeic acid) with NaIO 4. The structure of this hydrate was determined by spectroscopic methods.
Hiroyuki Tazaki, Mayumi Ito, Masako Miyoshi, Jun Kawabata, Eri Fukushi, Takashi Fujita, Mutsumi Motouri, Tatsuo Furuki, Kensuke Nabeta
Bioscience, Biotechnology and Biochemistry   66(2) 255-261   Feb 2002
The new caffeic acid derivative, subulatin (1), was isolated from in vitro cultured liverworts, Jungermannia subulata, Lophocolea heterophylla, and Scapania parvitexta. The structure of 1 involved two caffeic acids, D-glucose, and 2-carboxy-6-(1,2...
Hiroyuki Tazaki, Daisuke Taguchi, Takaomi Hayashida, Kensuke Nabeta
Bioscience, Biotechnology and Biochemistry   65(12) 2613-2621   Dec 2001
The formation of ortho-quinone from ortho-diphenol is a key step in its dimerization. An NMR analysis of the oxidation of 3,4-dihydroxycinnamic acid (caffeic acid) by NaIO4 revealed the formation of 3-(3′ ,4′-dioxo-1′ ,5′-cyclohexadienyl) propenoi...
Hiroyuki Tazaki
Nippon Nogeikagaku Kaishi   74(2) 137-143   Dec 2000
Hiroyuki Tazaki, Takaomi Hayashida, Tatsuwo Furuki, Kensuke Nabeta
Phytochemistry   52(8) 1551-1553   Dec 1999
A clerodane-type diterpenoid was isolated from Scapania bolandeli, and its structure was determined by extensive NMR spectroscopic techniques.
Hiroyuki Tazaki, Takeshi Iwasaki, Izumi Nakasuga, Kimiko Kobayashi, Hiroyuki Koshino, Masayasu Tanaka, Kensuke Nabeta
Phytochemistry   52(8) 1427-1430   Dec 1999
An ent-Kaurane-type diterpenoid, ent-kaurane-3,15-dione has been isolated from cell cultures of the liverwort Jungermannia subulata. Its structure was established by spectroscopic methods.
Hiroyuki Tazaki, Takeshi Iwasaki, Yukihiro Kawakami, Kensuke Nabeta
Bioscience, Biotechnology and Biochemistry   63(9) 1667-1668   Sep 1999
A 2H-NMR analysis of 6α-hydroxy-3-oxo-pinguis-5(10)-ene-11,6-olide produced by axenic culture of liverwort Aneura pinguis in the presence of [4-2H2]-labeled mevalonate clarified the presence of a 1,2-hydride shift and retention of deuterium at the...
Hiroyuki Tazaki, Hans Becker, Kensuke Nabeta
Phytochemistry   51(6) 743-750   Jul 1999
Three new seco-clerodane diterpenoids, jamesoniellides H, I and J have been isolated from axenic cultures of the liverwort Jamesoniella autumnalis. Their structures were determined by spectroscopic methods.
Hiroyuki Tazaki, Takaomi Hayashida, Mayumi Ito, Sayaka Minoshima, Tatsuwo Furuki, Kensuke Nabeta
Bioscience, Biotechnology and Biochemistry   63(7) 1238-1241   Jul 1999
The new lignan derivative, erimopyrone, was isolated from the liverwort, Moerckia erimona. Its structure was established as [1R, 2S]-1(6-carboxy-2-oxo-2H-4-pyranyl)-6,7-dihydroxy-1,2-dihydro-2,3- naphthalenedicarboxylic acid by spectroscopic methods.
Hiroyuki Tazaki, Takaomi Hayashida, Fumiko Ishikawa, Daisuke Taguchi, Toshihide Takasawa, Kensuke Nabeta
Tetrahedron Letters   40(1) 101-104   Jan 1999
The formation of the lignans in liverworts. Jamesonieila autumnalis and Lophocolea heterophylla was investigated. Feeding experiment of [8-2H] caffeic acid (4) on axenic cultures of J. autumnalis has shown that jamesopyrone (2) and scapaniapyrone ...
Hiroyuki Tazaki, Fumiko Ishikawa, Hiroshi Soutome, Kensuke Nabeta
Phytochemistry   48(5) 851-856   Jul 1998
Three new pinguisane-type sesquiterpenes, named grandilobalide A, B, and 6α-hydroxy-4,8-dimethoxycarbonyl-pinguis-11,6-olide, and a new rearranged pinguisane-type, named grandilobalide C, together with six known sesqui- and diterpenes, have been i...
Hiroyuki Tazaki, Kensuke Nabeta, Hans Becker
Phytochemistry   48(4) 681-685   Jun 1998
Six new clerodane-type diterpenoids have been isolated from axenic cultures of the liverwort Jamesoniella autumnalis. Their structures were elucidated on the basis of spectroscopic evidence.
Hiroyuki Tazaki, Tomoko Okihara, Hiroyuki Koshino, Kimiko Kobayashi, Kensuke Nabeta
Phytochemistry   48(1) 147-149   May 1998
A new aromadendrane-type sesquiterpenoid, 1,2-dehydro-3-oxo-β- gurjunene, together with known 1,4-dimethyl-azulene, has been isolated from the liverwort Calypogeia azurea grown in the field. The structure of 1,2- dehydro-3-oxo-β-gurjunene was esta...
Kensuke Nabeta, Kaori Komuro, Tomoaki Utoh, Hiroyuki Tazaki, Hiroyuki Koshino
Chemical Communications   (2) 169-170   Jan 1998
The 2H and 13C enrichment, 13C-13C coupling patterns and β-2H isotope shifts observed in β-barbatanol prepared from (-)-β-barbatene incorporating variously 2H- and 13C-labelled mevalonates, acetates and glycerol verifies a 1,4-hydrogen shift and a...
Hiroyuki Tazaki, Hiroshi Soutome, Takeshi Iwasaki, Kensuke Nabeta, Duilio Arigoni
Chemical Communications   (12) 1101-1102   Dec 1997
2H and 13C NMR analyses of 6α-hydroxy-3-oxopinguis-5(10)-ene-11,6-olide produced by axcenic cultures of the liverwort Aneura pinguis in the presence of 2H- and 13C-labelled mevalonates clarify the biosynthesis of pinguisane-type sesquiterpenes fro...
Hiroyuki Tazaki, Hiroshi Soutome, Kensuke Nabeta, Hiroshi Okuyama, Hans Becker
Phytochemistry   42(2) 465-468   Dec 1996
Three new pinguisane-type sesquiterpenes, 6α-hydroxy-3-oxo-pinguis-5(10)-ene-11,6-olide, 6α-methoxy-3-oxo-pinguis-5(10)-ene-11,6-olide and 3-oxo-pinguis-5(10),6-diene-11,6-olide, together with pinguisone, have been isolated from axenic culture of ...
Hiroyuki Tazaki, Klaus Peter Adam, Hans Becker
Phytochemistry   40(6) 1671-1675   Jan 1995
Five new lignan derivatives, 2,3,6′-tricarboxy-6,7-dihydroxy-1(3′)-2′-pyranonyl-1,2-dihydronaphthalene, its two monomethyl esters, 2,6′-dicarboxy-6,7-dihydroxy-1(3′)-2′-pyranonyl-1,2-dihydronaphthalene and 2,3-dicarboxy-6,7-dihydroxy-1-(3′,4′-dihy...
Hiroyuki Tazaki, Josef Zapp, Hans Becker
Phytochemistry   39(4) 859-868   Jan 1995
Nine new furanoditerpenoids, jamesoniellide D-J, and two new labdane-type diterpenoids together with 19-acetoxy-ent-labda-8 (17),12E,14-trien-3α-ol have been isolated from in vitro cultures of the liverwort Jamesoniella autumnalis. The structures ...
Hiroyuki Tazaki, Martin Blechschmidt, Volker Huch, Michael Veith, Hans Becker
Phytochemistry   37(2) 491-494   Jan 1994
A new furanoditerpenoid, jamesoniellide C, has been isolated from the liverwort Jamesoniella autumnalis. The structure of jamesoniellide C was established by spectroscopic methods, including X-ray analysis which also established its relative stere...
Kensuke Nabeta, Yuki Mototani, Hiroyuki Tazaki, Hiroshi Okuyama
Phytochemistry   35(4) 915-920   Jan 1994
A set of differently deuterated mevalonates ([6,6,6-2H3]-,[5,5-2H2]-, [4,4-2H2] and [2,2-2H2]-) was shown to be incorporated effectively into cadinanes including (1S)-7-methoxy-1,2-dihydrocadalene and (1S,4R)-7-hydroxycalamenene in suspension cult...
Hiroyuki Tazaki, Natsuko Ohta, Kensuke Nabeta, Hiroshi Okuyama, Masatosi Okumura, Masatosi Okumura
Phytochemistry   34(4) 1067-1070   Jan 1993
Two new glucosides of sesquiterpenoids and six known glucosides were isolated from potato (Solanum tuberosum, cv NOURIN ICHIGO) leaves and their structures deduced by spectral data. The distribution of glucosides of ionone-related compounds in lea...