MISC

1999年4月5日

Three-dimensional structure-function relationship of vitamin D: Side chain location and various activities

Bioorganic and Medicinal Chemistry Letters
  • Keiko Yamamoto
  • ,
  • Hiroshi Ooizumi
  • ,
  • Kazuhiko Umesono
  • ,
  • Annemieke Verstuyf
  • ,
  • Roger Bouillon
  • ,
  • Hector F. DeLuca
  • ,
  • Toshimasa Shinki
  • ,
  • Tatsuo Suda
  • ,
  • Sachiko Yamada

9
7
開始ページ
1041
終了ページ
1046
記述言語
英語
掲載種別
DOI
10.1016/S0960-894X(99)00129-8

The various biological activities of side-chain mobility restricted analogs, four diastereomers at C(20) and C(22) of 22-methyl-1α, 25- dihydroxyvitamin D3, were evaluated. The relationship between structure and the various activities of the analogs was discussed in terms of the active space region concept that we previously suggested.

リンク情報
DOI
https://doi.org/10.1016/S0960-894X(99)00129-8
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/10230636
ID情報
  • DOI : 10.1016/S0960-894X(99)00129-8
  • ISSN : 0960-894X
  • PubMed ID : 10230636
  • SCOPUS ID : 0033526059

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