八幡俊男 (Toshio Yawata) - マイポータル

基本情報

所属: 高知大学教育研究部医療学系臨床医学部門助教

学位: 医学博士(鳥取大学)

研究者番号: 40380323
J-GLOBAL ID: 200901071018431664
researchmap会員ID: 5000083549

研究キーワード

研究分野

経歴

2000年 - 2004年

米国がん研究所研究員 (NCI/NIH), Laboratory of Biosystems and Cancer
2000年 - 2004年

Visiting Fellow, National Cancer Institute,
2004年

- 高知大学医学部助手, 脳神経外科
2004年

- Assistant Professor, faculty of medicine,
1999年 - 2000年

米国環境健康科学研究所研究員 (NIEHS/NIH), Laboratory of Molecular Carcinogenesis
1999年 - 2000年

Visiting Fellow, National Institute of
1998年 - 1999年

鳥取大学中核的研究機関研究員
1998年 - 1999年

Research Fellow in the Core Research
Kochi Unversity
NIH
Environmental Health Science, NIH
Medicine, Tottori University, JAPAN
Genetics, School of Life Science, Faculty of
Institute, Department of Molecular and Cell

学歴

論文

The role of diurnal fluctuations in excitatory amino acid carrier 1 levels in post-ischemic hippocampal Zn2+ accumulation.

Takaaki Aratake, Youichirou Higashi, Tomoya Hamada, Yusuke Ueba, Takahiro Shimizu, Shogo Shimizu, Toshio Yawata, Tetsuya Ueba, Motoaki Saito

Experimental neurology 336 113538-113538 2021年2月
Targeting CD146 using folic acid-conjugated nanoparticles and suppression of tumor growth in a mouse glioma model

Fukui N, Yawata T, Nakajo T, Kawanishi Y, Higashi Y, Yamashita T, Aratake T, Honke K, Ueba T

Journal of Neurosurgery 1-11 2020年7月査読有り責任著者
Zinc-aggravated M1 microglia regulate astrocytic engulfment via P2×7 receptors.

Tomoya Hamada, Takaaki Aratake, Youichirou Higashi, Yusuke Ueba, Takahiro Shimizu, Shogo Shimizu, Toshio Yawata, Tetsuya Ueba, Rina Nakamura, Toshifumi Akizawa …

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 61 126518-126518 2020年4月11日査読有り
CD146 is highly expressed in glioma stem cells and acts as a cell cycle regulator.

Yawata T, Higashi Y, Kawanishi Y, Nakajo T, Fukui N, Fukuda H, Ueba T

Journal of Neuro-oncology 144(1) 21-32 2019年5月査読有り筆頭著者責任著者
Efficient delivery of small interfering RNAs targeting particular mRNAs into pancreatic cancer cells inhibits invasiveness and metastasis of pancreatic tumors.

Taniuchi K, Yawata T, Tsuboi M, Ueba T, Saibara T

Oncotarget 10 2869-2886 2019年4月査読有り
Attenuation of zinc-enhanced inflammatory M1 phenotype of microglia by peridinin protects against short-term spatial-memory impairment following cerebral ischemia in mice.

Yusuke Ueba, Takaaki Aratake, Ken-Ichi Onodera, Youichirou Higashi, Tomoya Hamada, Takahiro Shimizu, Shogo Shimizu, Toshio Yawata, Rina Nakamura, Toshifumi Akizawa …

Biochemical and biophysical research communications 507(1-4) 476-483 2018年12月9日査読有り
The inhibitory role of intracellular free zinc in the regulation of Arg-1 expression in interleukin-4-induced activation of M2 microglia.

Aratake T, Higashi Y, Ueba Y, Hamada T, Shimizu T, Shimizu S, Yawata T, Ueba T, Saito M

Metallomics 10 1501-1509 2018年9月査読有り
Stimulation of brain nicotinic acetylcholine receptors activates adrenomedullary outflow via brain inducible NO synthase‐mediated S‐nitrosylation

Youichirou Higashi, Takahiro Shimizu, Masaki Yamamoto, Kenjiro Tanaka, Toshio Yawata, Shogo Shimizu, Suo Zou, Tetsuya Ueba, Kazunari Yuri, Motoaki Saito

British Journal of Pharmacology 175(19) 3758-3772 2018年8月12日
Stimulation of brain nicotinic acetylcholine receptors activates adrenomedullary outflow via brain inducible NO synthase-mediated S-nitrosylation.

Higashi Y, Shimizu T, Yamamoto M, Tanaka K, Yawata T, Shimizu S, Zou S, Ueba T, Yuri K, Saito M

Br J Pharmacol 175(19) 3758-3772 2018年7月査読有り
Influence of extracellular zinc on M1 microglial activation.

Youichirou Higashi, Takaaki Aratake, Shogo Shimizu, Takahiro Shimizu, Kumiko Nakamura, Masayuki Tsuda, Toshio Yawata, Tetuya Ueba, Motoaki Saito

Scientific reports 7 43778-43778 2017年2月27日査読有り
[Melanoma cell adhesion molecule (MCAM)/CD146 is a novel marker for malignant glioma].

Toshio Yawata, Tetsuya Ueba

Nihon rinsho. Japanese journal of clinical medicine 74 Suppl 7 268-73 2016年9月査読有り
Adult CNS/supratentorial primitive neuroectodermal tumor(PNET)の一例

近藤雄一郎, 川西裕, 八幡俊男, 濱田史泰, 上羽佑亮, 中居永一, 福井直樹, 上羽哲也, 弘井誠

Brain Tumor Pathology 33(Suppl.) 148-148 2016年5月
Brain opioid and nociceptin receptors are involved in regulation of bombesin-induced activation of central sympatho-adrenomedullary outflow in the rat.

Toshio Yawata, Youichirou Higashi, Takahiro Shimizu, Shogo Shimizu, Kumiko Nakamura, Keisuke Taniuchi, Tetsuya Ueba, Motoaki Saito

Molecular and cellular biochemistry 411(1-2) 201-11 2016年1月査読有り
Possible inhibitory role of endogenous 2-arachidonoylglycerol as an endocannabinoid in (±)-epibatidine-induced activation of central adrenomedullary outflow in the rat.

Takahiro Shimizu, Kenjiro Tanaka, Shogo Shimizu, Youichirou Higashi, Toshio Yawata, Kumiko Nakamura, Keisuke Taniuchi, Tetsuya Ueba, Kazunari Yuri, Motoaki Saito

Neuropharmacology 95 278-89 2015年8月査読有り
Prevalence of human cytomegalovirus, polyomaviruses, and oncogenic viruses in glioblastoma among Japanese subjects.

Yumiko Hashida, Ayuko Taniguchi, Toshio Yawata, Sena Hosokawa, Masanao Murakami, Makoto Hiroi, Tetsuya Ueba, Masanori Daibata

Infectious agents and cancer 10 3-3 2015年査読有り
Elevated cell invasion in a tumor sphere culture of RSV-M mouse glioma cells.

Motonobu Nonaka, Toshio Yawata, Mitsuhiro Takemura, Youichirou Higashi, Eiichi Nakai, Keiji Shimizu, Tetsuya Ueba

Neurologia medico-chirurgica 55(1) 60-70 2015年査読有り責任著者
Angiotensin II acting on brain AT1 receptors induces adrenaline secretion and pressor responses in the rat.

Kumiko Nakamura, Takahiro Shimizu, Toshihiko Yanagita, Takayuki Nemoto, Keisuke Taniuchi, Shogo Shimizu, Fotios Dimitriadis, Toshio Yawata, Youichirou Higashi, Tetsuya Ueba …

Scientific reports 4 7248-7248 2014年11月28日査読有り
Suppression of oxidative stress and 5-lipoxygenase activation by edaravone improves depressive-like behavior after concussion.

Youichirou Higashi, Michihiro Hoshijima, Toshio Yawata, Atsuya Nobumoto, Masayuki Tsuda, Takahiro Shimizu, Motoaki Saito, Tetuya Ueba

Journal of neurotrauma 31(20) 1689-99 2014年10月15日査読有り
Possible involvement of brain prostaglandin E2 and prostanoid EP3 receptors in prostaglandin E2 glycerol ester-induced activation of central sympathetic outflow in the rat.

Takahiro Shimizu, Kenjiro Tanaka, Kumiko Nakamura, Keisuke Taniuchi, Toshio Yawata, Youichirou Higashi, Tetsuya Ueba, Fotios Dimitriadis, Shogo Shimizu, Kunihiko Yokotani …

Neuropharmacology 82 19-27 2014年7月査読有り
Efficient siRNA delivery and tumor accumulation mediated by ionically cross-linked folic acid-poly(ethylene glycol)-chitosan oligosaccharide lactate nanoparticles: for the potential targeted ovarian cancer gene therapy.

Tony Shing Chau Li, Toshio Yawata, Koichi Honke

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 52 48-61 2014年2月14日査読有り