論文

国際誌
2021年11月10日

Associations between prenatal exposure to volatile organic compounds and neurodevelopment in 12-month-old children: The Japan Environment and Children's Study (JECS).

The Science of the total environment
  • Hiroko Nakaoka
  • Aya Hisada
  • Daisuke Matsuzawa
  • Midori Yamamoto
  • Chisato Mori
  • Michihiro Kamijima
  • Shin Yamazaki
  • Yukihiro Ohya
  • Reiko Kishi
  • Nobuo Yaegashi
  • Koichi Hashimoto
  • Chisato Mori
  • Shuichi Ito
  • Zentaro Yamagata
  • Hidekuni Inadera
  • Takeo Nakayama
  • Hiroyasu Iso
  • Masayuki Shima
  • Youichi Kurozawa
  • Narufumi Suganuma
  • Koichi Kusuhara
  • Takahiko Katoh
  • 全て表示

794
開始ページ
148643
終了ページ
148643
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.scitotenv.2021.148643

In recent years, there has been an increase in the number of problems associated with neurodevelopmental disorders in children, and there has been a growing interest in the relationship between environmental chemicals and children's health. The objective of this study was to examine whether an association exists between occupational or environmental prenatal maternal exposure to volatile organic compounds and the risk of neurodevelopmental disorders in children using Japanese translations of the Ages & Stages Questionnaires, Third Edition (J-ASQ-3). An increase in the risk of neurodevelopmental delay in 12-month-old children associated with maternal exposure to formalin or formaldehyde was identified in terms of problem-solving (odds ratio (OR): 1.76, 95% confidence interval (CI): 0.99-3.12) and personal-social skills (OR: 3.32, 95% CI: 1.46-7.55). It is not clear whether or not this tendency is reversible, and whether it is observed past 12 months of age. Further research and a preventive approach are needed.

リンク情報
DOI
https://doi.org/10.1016/j.scitotenv.2021.148643
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34198080
ID情報
  • DOI : 10.1016/j.scitotenv.2021.148643
  • PubMed ID : 34198080

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