2016年2月1日
Calibration between the estimated probability of the risk assessment chart of Japan atherosclerosis society and actual mortality using external population
Journal of Atherosclerosis and Thrombosis
- 巻
- 23
- 号
- 2
- 開始ページ
- 176
- 終了ページ
- 195
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.5551/jat.31286
- 出版者・発行元
- 一般社団法人 日本動脈硬化学会
<p>Aim: In Japan Atherosclerosis Society guidelines for the prevention of atherosclerotic cardiovascular diseases 2012 (JAS2012), NIPPON DATA80 risk assessment chart (ND80RAC) was adopted to estimate the 10-year probability of coronary artery disease (CAD) mortality. However, there was no comparison between the estimated mortality calculated by ND80RAC and actual mortality in external populations. Accordingly, we used the large pooled database of cohorts in Japan, EPOCH-JAPAN, as an external population.Methods:The participants of EPOCH-JAPAN without a history of cardiovascular disease (15,091 men and 18,589 women aged 40–74 years) were analyzed based on sex. The probability of a 10-year risk of CAD/stroke mortality was estimated by ND80RAC. The participants were divided into both decile of their estimated mortality and three categories according to JAS2012. The calibration between the mean estimated mortality and the actual mortality was performed by the Hosmer and Lemeshow (H-L) test.Results: In both sexes, the estimated CAD mortality was higher than the actual mortality, particularly in higher deciles of estimated mortality, and the estimated stroke mortality was almost concord
- リンク情報
- ID情報
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- DOI : 10.5551/jat.31286
- ISSN : 1340-3478
- CiNii Articles ID : 130005122027