Evidence for the expression of neonatal skeletal myosin heavy chain in primary myocardium and cardiac conduction tissue in the developing chick heart(Tokyo Women's Medical University)
Tatsuguchi M, Hiratsuka E, Machida S, Nishikawa T, Imamura S, Shimizu S, Nishimura M, Komuro I, Furutani Y, Furutani M, Nagao H, Komatsu K, Kasanuki H, Matsuoka R
Journal of muscle research and cell motility 25 69-76 2004 [Refereed]
Amano A, Kondo Y, Noda Y, Ohta M, Kawanishi N, Machida S, Mitsuhashi K, Senmaru T, Fukui M, Takaoka O, Mori T, Kitawaki J, Ono M, Saibara T, Obayashi H, Ishigami A
Arch Biochem Biophys 622 47-58 May 2017 [Refereed]
Developmental Dynamics 217 37-49 Jan 2000 [Refereed]
We isolated a neonatal skeletal myosin heavy chain (MHC) cDNA clone, CV11E1, from a cDNA library of embryonic chick ventricle. At early cardiogenesis, diffuse expression of neonatal skeletal MHC mRNA was first detected in the heart tube at stage 1...
Japan is the most-advanced country with a declining birth rate and a growing proportion of elderly people. It is important to prepare social support to improve the health and environment of the elderly generation to maintain their health and abili...
Japan Science and Technology Agency: Center of Innovation (COI) Program
Project Year: 2013 - 2014
Japan is the most-advanced country with a declining birth rate and a growing proportion of elderly people. It is important to prepare social support to improve the health and environment of the elderly generation to maintain their health and abili...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research
Project Year: Apr 2012 - Mar 2013 Investigator(s): 町田 修一
Sarcopenia is characterized by a progressive decrease of skeletal muscle mass and function (strength or performance) with aging. Sarcopenia has become a highly significant public health problem, physical disability, metabolic syndrome and cardiova...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research
Project Year: 2009 - 2012 Investigator(s): 春日 規克
The recruitment of satellite cells, which are located between the basement membrane and the plasma membrane in myofibers, is controlled by muscle injury or overload, several growth factor. It is poorly understood how the satellite cell migration i...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research
Project Year: 2010 - 2011 Investigator(s): 黒坂 光寿
We examined the effect of exercise-and sarcopenia-induced interleukin-6(IL-6) on the proliferative potential of satellite cells in primary cell culture. We demonstrated that IL-6 has an effect on proliferative potential of satellite cells in a dos...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research
Project Year: 2009 - 2011 Investigator(s): 鈴木 政登
The present study was conducted to examine whether a decrease in energy expenditure caused by reduced physical activity during childhood or an increase in energy intake caused by overeating during childhood was responsible for resetting the set po...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research
Project Year: 2006 - 2009 Investigator(s): 芝山 秀太
We investigated the elucidation of molecular and cellular mechanisms of the improvement effect of mental health following a physical exercise using experimental animal models and humans ; and we applied all these fundamental research resources to ...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research
Project Year: 2006 - 2007 Investigator(s): 真田 樹義
Little information is available regarding the relationships among human obesity-related genes, cardiorespiratory fitness and metabolic syndrome (MS) or predisposition to MS (MP). The purpose of this study was to investigate the contribution of obe...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research
Project Year: 2005 - 2007 Investigator(s): 竹倉 宏明
The transverse (t) -tubule is responsible for the rapid inward spread of excitation from the sarcolemma to the inside of the muscle fiber, and the compartments of the t-tubule become highly and regularly organized during development. Although it i...
