MISC

2007年

The development and evaluation of a prototype system for the inference of genetic networks based on genetic programming

WMSCI 2007: 11TH WORLD MULTI-CONFERENCE ON SYSTEMICS, CYBERNETICS AND INFORMATICS, VOL IV, PROCEEDINGS
  • Kouji Tanaka
  • ,
  • Hayato Yamana

4
開始ページ
13
終了ページ
18
記述言語
英語
掲載種別
出版者・発行元
INT INST INFORMATICS & SYSTEMICS

Estimating mutual interactions of genetic networks is mainly to infer the mutual control relationships from multiple genes from the gene expression data. Such correlations are typically expressible in the form of nonlinear simultaneous differential equations. However, most work to date has employed S-systems as an expression of such differential equations, allowing only rough approximations of mass actions, and as such it was difficult to determine the actual correlations between the genes. Instead, we formulate the mutual interactions as actual simultaneous partial differential equations, and automatically determine its structure and coefficients using genetic programming (GP) from a given data series. Parallel implementation of the scheme in a Grid environment using our Jojo Grid programming system for Java has resulted in precise determination of the equations in many cases within some reasonable time.

リンク情報
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000254644200003&DestApp=WOS_CPL
ID情報
  • Web of Science ID : WOS:000254644200003

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