KOJIMA HIROSHI

J-GLOBAL         Last updated: Mar 9, 2017 at 22:34
 
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Name
KOJIMA HIROSHI
URL
http://www.tamagawa.ac.jp/teachers/noomiso.fueru/index.html
Affiliation
Tamagawa University
Section
College of Engineering, Department of Intelligent Mechanical Systems
Job title
Professor

Profile

My research speciality is as follows: Elucidation of synaptic function of the central nervous system by neurophysiological and molecular biological approaches. The tequeniques used for purpose are electrophysiology (single channel recording), imaging (laser microscope etc.) analysis, and pharmacological treatment. Especially, introducing molecular biological approaches into these fields are one of the important present topics.I had been worked in several research organizations for more than 1Biochemistry I(protein and enzyme), "Biochemistry II(metabolism)", "Biochemistry III (molecular genetics)", "Neurophysiology", "Physiology of Behaviour", "Biological information system", "Biological functional system", "Outline of Robotics", "Biomelecula engineering" etc. are my lecture subjects. Experimental lecture are "Neuroinformation seminar", "Foundamental experiments of engineering".

Academic & Professional Experience

 
Apr 2005
 - 
Today
Dept. of Intelligent Information Systems, Tamagawa Academy
 
May 2003
 - 
Mar 2005
Brain Science Research Center, Tamagawa Academy
 
Oct 2001
 - 
Apr 2003
Dept. of Molecular Biology, Princeton University (USA)
 
Dec 1999
 - 
Sep 2001
Centre National de la Recherche Scientifique (France)
 
Apr 1994
 - 
Nov 1999
Laboratory for Synaptic Function, Institute of Physical and Chemical Research
 
Apr 1990
 - 
Mar 1994
Dept. of Pharmacology, University College London (UK)
 
Jan 1986
 - 
Mar 1990
Dept. of Physiology and Pharmacology, University of North Carolina, Northwestern University
 
Apr 1985
 - 
Dec 1986
Japan Society of Promotion for Science
 

Education

 
Apr 1980
 - 
Mar 1985
Physiology, Graduate School of Medicine, Kyoto University
 
Apr 1977
 - 
Mar 1980
Nuclear Engineering, Graduate School of Engineering, Kyoto University
 
Apr 1975
 - 
Mar 1977
Nuclear Engineering, Graduate School of Engineering, Kyoto University
 
Apr 1971
 - 
Mar 1975
Nuclear Engineering, Faculty of Engineering, Kyushu University
 

Published Papers

 
A study on the synaptic transmission of cerebellar Purkinje cells and its history
Hiroshi KOJIMA
Bulletin de la Soci?t? Franco-Japonaise de Biologie   55 1-3   Jun 2016   [Refereed]
Quantum Mechanical Approach to Brain Function
Hiroshi KOJIMA
Memoirs of The College of Engineering, Tamagawa University   (51) 1-20   Apr 2016   [Refereed]
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6 15-37   Jan 2013   [Refereed]
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48 51-74   Jan 2013
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1(1) 1-15   Mar 2012

Misc

 
Quantum Mechanical Approach to Brain Function
Hiroshi KOJIMA
Memoirs of The College of Engineering, Tamagawa University   (51) 1-20   2016
A study on the synaptic transmission of cerebellar Purkinje cells and its history
Hiroshi KOJIMA
Bulletin de la Soci?t? Franco-Japonaise de Biologie   55 1-3   2016
An Analysis of AMPA receptor kinetics during synaptic efficacy change in cerebellar Purkinje cell. Invited Seminar, Saga University Medical School
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-      2010
Analysis of the Spatial-Temporal Characteristics of Synaptic EPSP Summation on the Dendritic Trees of Hippocampal CA1 Pyramidal Neurons as Revealved by Laser Uncaging Stimulation
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Journal of the Japan Neural Network Society   17(1) 2-11   2010
A study of synaptic plasticity by glutamate receptor channel kinetics models--future application of 2-photon laser photolysis
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The Journal of Physiological Sicences suppl.   60 463   2009
Analysis of synaptic transmission mediated by AMPAR channel with TARP(gamma7)
International Congress of Physiological Sciences
The Journal of Physiological Sciences suppl.   60 135   2009
An analysis of synaptic transmission mediated by AMPA receptor channels and possible role of TARP (γ7)
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Neuroscience Research Suppl.   65 S80   2009
A study of synaptic transmission of cerebellar Purkinje cells by laser photolysis and glutamate receptor channel kinetics model Society for Neuroscience
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Society for Neuroscience   12090   2009
An analysis of synaptic transmission mediated with AMPA receptor channels by laser photolysis (II)
H. Kojima, C. Toyoshima, A. Kawaguchi, S. Toujou, S. Nakamura
Neuroscience Research Suppl.   65 S80   2009
A physiological and molecular biological study of rat cerebellar long-term depression
Biophysical Society of the USA
Proceeding of the Biophysical Society   1375-Pos/B219   2009
A system for rapid patterned photolysis by ultraviolet (UV) laser beam
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-   43 13-22   2008
An analysis of synaptic transmission by AMPAR channel kinetics model
Neuroacience Society of Japan
Neuroscience Research suppl.   61(Suppl. 1) S216   2008
An analysis of synaptic transmission by laser and kinetics model
Society for Neuroscience of USA
Society for Neuroscience   S-10771   2008
An analysis of synaptic transmission and its plasticity by glutamate receptor channel kinetics models and 2-photon laser photolysis
KEDRI
Proceedings of ICONIP   1    2008
Properties of synaptic transmission by UV and IR laser photolysis and its application
Society for Neuroscience
Society for Neurosciecne USA      2007
Analysis of synaptic transmission by UV and IR laser photolysis. Neuroscience Research
Tadaharu Tsumoto
Neuroscience Research Suppl.   58(S1) S43   2007
Imaging analysis of associative LTP in rat hippocampus CA1 region
Yasunobu Okada
The Journal of Physiological Sciences, Suppl.   56 S84   2006
A system for rapid uncaging in defined patterns and its application
Tadaharu Tsumoto
Neuroscience Research Suppl.   55(S1) S67   2006
Multi-point synaptic activation by UV-laser uncaging system.
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Society for Neuroscience USA      2006
Development of a system for patterned rapid photolysis and 2-photon confocal microscopy
Ilko Ilev
IEEE Circuit and Device (Laser and Electro-optical Society) Magazine.   22(6) 66-74   2006
A graphical analysis of synaptic transmission in Aplysia
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Japanese Journal of Physiology   S152    2005
A graphical analysis of synaptic transmission in Aplysia.
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Japanese Journal of Physiology Suppl.   S152   2005
The requirement of back-propagating action potentials to the induction of associative LTP in hippocampal CA1 pyramidal neurons
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Neuroscience Research Suppl.      2005
Application of modified non-stationary analysis for the inhibitory synaptic transmission in Aplysia
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Tamagawa University Research Review   10 1-18   2004
High sensitivity of Mouse neuronal cells to Tetanus Toxin requires a GPI-anchored protein
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Japanese Journal of Physiology, Suppl.   54(306) S142   2004
Experimental investigation of dynamical model of learning and memory.
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Proceedings of the Sentan-nou   p159   2004
Enhancement of optical signals recorded from CA1 of CaMKII-transgenic mouse during long-term potentiation.
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Neuroscience Research Suppl.   50(S1) OG3-10   2004
Important role of rafts and GPI-anchored proteins in neurone sensitivity to TeNT
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Soc. for Neuroscience USA   114   2004
Rac GTPase Plays an Essential Role in Exocytosis by Controlling the Fusion Competence of Release Sites.
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The Journal of Neuroscience   22(18) 7968-7981   2002
Interaction of tetanus toxin with a GPI-anchored protein at the surface of mouse neural cells
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Proceedings of the ETOX Meeting.      2001
Determination de l’etape du processus d’exocytose bloquee par les BoNT/A et B et la TeNT par l’analyse des fluctuation d $B!G (Bamplitude de responses synaptique. (in French)
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Proceedings of the 4th reunion du Club Exocytose      2001
La toxine l’atale de C. Sordellii reduite le nombre de sites de liberation. (in French)
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Proceedings of the 4th reunion du Clob Exocytose      2001
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Biochemical and Biophysical Research Communication   289 623-629   2001
Properties of AMPA receptor channels during long-term depression in rat cerebellar Purkinje cell.
Eds by K. Kuba, H. Higashida, DA. Brown, T. Yoshioka
Slow Synaptic Response and Modulation   307-314   2000
Novel targets for alcohol action: Gprotein-activated inwardly rectifying potassium channels
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Neurosceince Res. Suppl.   S126 24   2000
Lethal toxin from C. sordellii inhibits a late step in neuroexocytosis. (in French)
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Proceedings of the XIIIth World Congress of the Internationel Society of Toxinology   L30    2000
Votre neurotoxin peferee bloque la transmission synaptique ? (in French),
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Societe Francaise d’Etude des Toxin      2000
Les neurotoxines de Clostridium: des toxines agissant sur la transmission synaptique (in French)
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Bull. Soc. Francaise de Microbiologie   15(2) 81-89   2000
Bacterial toxin: Tool to ditect the transmission between multiple synapstic vesicles stores during neurotransmitter release ans synaptic plasticity
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Biology of the Cell   92(6) 468-469   2000
Change in agonist sensitivity of neurons in Lateral Amygdala of NMDAR2 deficient mouse and its relationship with formation of fear conditioning
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Neuroscience Ressearch Suppl.   S60 054   1999
A functional localization of phospholipase Cb isozymes and selective coupling with metabotropic glutamate receptors in mouse cerebellum
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Neuroscience Reaserch Suppl.   S114 217   1999
Development of Infrared DIC Video Microscopy and its Application to Unstained Cells in Living Preparations.
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Bioimages   6(1) 9-19   1998
Observation of retina of SD rat with infrared differential interference contrast video microscopy
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Journal Kyorin Medical Soc   29 p169   1998
A study of the Glutamate receptor channels of rat cerebellar Purkinje cell.
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Soc. for Neuroscienc. USA   24(2) 1272   1998
A study of the Glutamate receptor channels of rat cerebellar Purkinje cell.
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Neuroscience Research Suppl.   S84 074   1998
A study of the Glutamate receptor channels of rat cerebellar Purkinje cell.
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Soc. for Neuroscience USA   S84 074   1998
Calcium Response in the Brain Nuclei Related to Auditory Fear Conditioned Learning
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Neuroscience Research Suppl.   S229 482   1998
Application of Variance Analysis to Synaptic Current during Long-term Depression Recorded from Cerebellar Purkinje Cell of Rat
N. Elsner and H. Wassle, Georg Thieme verlag Stuttgart New York
From Membrane to Mind ed.   141   1997
Characteristics of AMPA receptor channels during long-term depression of Purkinje cell of rat
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Neuroscience Research, suppl   21 S62   1997
Non-stationary Noise Analysis and its Application to Synaptic Plasticity
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Proceedings of the 1997 International Symposium on Nonlinear Theory and its Applications (NOLTA’97),   685-688   1997
Study of the basic mechanisms of Long-term depression of rat cerebellum.
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Proceedings of the 1997 IEICE Transaction, ME and Biocybanetics   MBE 1-8   1997
Visualizing Unstained Cells in Living Preparations by Improved Infrared DIC-Video Microscopy
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Roken Review   (12) 59-60   1996
Comparison of Neuronal Nicotinic Receptors in Rat Sympathetic Neurones with Subunit Pairs Expressed in Xenopus Oocytes.
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Japanese Journal of Physiology suppl.   45(2) S3-16   1995
Kinetics of AMPA Receptor during Long-term Depression in Cerebellar Purkinje Cells
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Proceedings of the 4th IBRO World Congr. of Neuroscience   B3 71   1995
Expression of Cloned Acetylcholine Receptor Subunit in Xenopus Oocyte Produces Heterogeneous Receptors
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Proceedings of the 2nd Int. Confer. On New Directions in Affective Disorders, Jerusalem P100   p100   1995
Kinetics of AMPA receptor channels in cerebellar Purkinje cells in rat compared with those in cultured Purkinje cell
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European Neuroscience Assoc.   50.20   1995
Relative agonist potencies at neuronal nicotinic receptors: a comparison between ganglionic and recombinant receptors
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British Journal of Pharmacology, suppl   112(362) p362   1994
The synaptic currents recorded from the Purkinje cells of the rat cerebellum by the whole cell patch-clamp technique
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Neuroscience Research, suppl.   19 S28   1994
Comparison of neuronal nicotinic receptors in rat sympathetic neurons with subunit pairs expressed in Xenopus oocytes
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Journal of Physiology.(London)   481(1) 27-34   1994
Change of nicotinic AChR channels in B-cells of bullfrog sympathetic ganglion during development
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Neuroscience Research, suppl   18 S112   1993
Neuronal nicotinic ACh receptors expression in Xenopus oocytes by cDNA injection into nucleus
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-   161(12) 955-957   1992
Change in properties of nicotinic ACh receptor channels in bullfrog sympathetic ganglion cells during development
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Proceedings of the British Pharmacological Society   128    1992
Expression of cloned receptor subunits produces multiple receptors.
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Proc. R. Soc. London B   242 109-112   1990
Effect of stimulation to the ventral root on cat hindlimb motoneurones.
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J. Physiol. Soc. Japan   47 P27   1988
Two types of single channel calcium channel currents in NG 108-15 cell
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Soc. for Neuroscience UAS   56(6)    1988
Synaptic channel kinetics of sympathetic neurons developing in vivo.
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Soc. for Neuroscience   147(6)    1986
Existence of low threshold sodium potentials in the cockroach giant axon.
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J. Physiol. Soc. Japan   47 P25   1985
Properties of miniature inhibitory postsynaptic potentials in rat spinal motoneurones
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J. Physiol. Soc. Japan   47 p418   1985
Synaptic actions of the ventral root afferents on cat hindlimb motoneurons
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Neuroscience Letters   58 201-205   1985
Characterization of miniature inhibitory postsynaptic potentials in rat spinal motoneurones
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Journal of Physiology (London)   368 625-640   1985
Low threshold, slow-inactivating Na potentials in the cockroach giant axon.
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Journal of Neurophysiology   54(5) 1087-1100   1985
Identification of inhibitory interneurons projecting to the cortical pyramidal tract cell by cross correlation method
Elsevier
Neuroscience Letters, Supplement   9 S48   1982
Output characteristics of pyramidal tract cells in the parietalcortex of the cat
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J. Physiol. Soc. Japan   44(8,9) 385   1982
Functional differentiation of pyramidal tract cells in the motor, somatosensory and parietal cortices of the cat
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Neuroscience Letters, Supplement   10    1982
Analysis of synaptic potentials by mathematical cable neuron model.
National Institute of Physisiological sciences
Mathematical Method in Physiology   1 85-86   1981
Properties of thalamic neurons receiving inputs from RF and projecting to the motor cortex.
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Electroencephalography and Clinical Neurophysiology   52(3)    1981
Britishi Physical Society
Journal of Physics   B12 3579-3589   1979
Physical Society of Japan
Journal of Physical Society of Japan   47 234-239   1979
Physical Society of Japan
Journal of Physical Society of Japan   46 198-204   1979
Auger electrons emitted from zinc and cadmium vapors by proton and alpha particle bombardments.
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Kyoto University      1977

Books etc

 
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Nov 2016   
Physiology of neurons and synapses
Sep 2016   
French Scientific Philosophy and Historical Origin of Neurophysiology
Sep 2016   
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Feb 2014   ISBN:4621086464
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Nov 2013   ISBN:3642305733
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Feb 2013   ISBN:4254102593
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Mar 2009   ISBN:978-4-87698-773-3
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Apr 2000   ISBN:4-431-70249-0
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Dec 1999   ISBN:4-925089-05-6
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Oct 1999   

Conference Activities & Talks

 
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-   22 Jul 2016   
An Electrophysiological Study of Synaptic Transmission and its Historical Background
182nd Meeting of the Society of Franco-Japonais Biology   1 Jun 2015   
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-   30 Sep 2014   
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第77回 日本心理学会大会   1 Oct 2013   
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-   30 Sep 2012   

Research Grants & Projects

 
Synthesis of a new caged compound for neural network analysis
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Project Year: Apr 2011 - Mar 2012
Development of fast multi point uncaging system and its application for neural network analysis
Project Year: Apr 2011 - Mar 2012
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Project Year: Apr 2011 - Mar 2012
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Project Year: Apr 2011 - Mar 2012