TAKEDA Shu

J-GLOBAL         Last updated: Aug 13, 2015 at 11:03
 
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Name
TAKEDA Shu
Affiliation
Tokyo Medical and Dental University
Section
Graduate School of Medical and Dental Sciences

Research Interests

 
 

Research Areas

 
 

Awards & Honors

 
1997
President Book Award
 

Published Papers

 
Bauer O, Sharir A, Kimura A, Hantisteanu S, Takeda S, Groner Y
Molecular and cellular biology   35(7) 1097-1109   Apr 2015   [Refereed]
Ma C, Fukuda T, Ochi H, Sunamura S, Xu C, Xu R, Okawa A, Takeda S
Molecular metabolism   4(3) 175-185   Mar 2015   [Refereed]
Suzuki W, Yamada A, Aizawa R, Suzuki D, Kassai H, Harada T, Nakayama M, Nagahama R, Maki K, Takeda S, Yamamoto M, Aiba A, Baba K, Kamijo R
Endocrinology   156(1) 314-322   Jan 2015   [Refereed]
Ochi H, Takeda S
Gerontology   61(4) 319-326   2015   [Refereed]
Muraoka N, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Isomi M, Nakashima H, Akiyama M, Wada R, Inagawa K, Nishiyama T, Kaneda R, Fukuda T, Takeda S, Tohyama S, Hashimoto H, Kawamura Y, Goshima N, Aeba R, Yamagishi H, Fukuda K, Ieda M
The EMBO journal   33(14) 1565-1581   Jul 2014   [Refereed]
Enoki Y, Sato T, Tanaka S, Iwata T, Usui M, Takeda S, Kokabu S, Matsumoto M, Okubo M, Nakashima K, Yamato M, Okano T, Fukuda T, Chida D, Imai Y, Yasuda H, Nishihara T, Akita M, Oda H, Okazaki Y, Suda T, Yoda T
FEBS letters   588(14) 2262-2269   Jun 2014   [Refereed]
Nakamoto A, Sato T, Hirosawa N, Nakamoto N, Enoki Y, Chida D, Usui M, Takeda S, Nagai T, Sasaki A, Sakamoto Y, Yoda T
International journal of oral and maxillofacial surgery   43(1) 113-119   Jan 2014   [Refereed]
Implication of vitamin E in bone metabolism
TAKEDA Shu
Osteoporosis International   25 568-568   2014   [Refereed]
Takarada T, Hinoi E, Nakazato R, Ochi H, Xu C, Tsuchikane A, Takeda S, Karsenty G, Abe T, Kiyonari H, Yoneda Y
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research   28(10) 2064-2069   Oct 2013   [Refereed]
Piao J, Tsuji K, Ochi H, Iwata M, Koga D, Okawa A, Morita S, Takeda S, Asou Y
Scientific reports   3 3022   Oct 2013   [Refereed]
Fukuda T, Takeda S, Xu R, Ochi H, Sunamura S, Sato T, Shibata S, Yoshida Y, Gu Z, Kimura A, Ma C, Xu C, Bando W, Fujita K, Shinomiya K, Hirai T, Asou Y, Enomoto M, Okano H, Okawa A, Itoh H
Nature   497(7450) 490-493   May 2013   [Refereed]
Itoh S, Sekino Y, Shinomiya K, Takeda S
Journal of bone and mineral metabolism   31(2) 206-211   Mar 2013   [Refereed]
Kohata K, Itoh S, Takeda S, Kanai M, Yoshioka T, Suzuki H, Yamashita K
Bio-medical materials and engineering   23(6) 485-493   2013   [Refereed]
Kinouchi K, Ichihara A, Sano M, Sun-Wada GH, Wada Y, Ochi H, Fukuda T, Bokuda K, Kurosawa H, Yoshida N, Takeda S, Fukuda K, Itoh H
PloS one   8(11) e78603   2013   [Refereed]
Hanyu R, Wehbi VL, Hayata T, Moriya S, Feinstein TN, Ezura Y, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Takeda S, Kaneko K, Kurosawa H, Karsenty G, Kronenberg HM, Vilardaga JP, Noda M
Proceedings of the National Academy of Sciences of the United States of America   109(19) 7433-7438   May 2012   [Refereed]
Hinoi E, Ochi H, Takarada T, Nakatani E, Iezaki T, Nakajima H, Fujita H, Takahata Y, Hidano S, Kobayashi T, Takeda S, Yoneda Y
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research   27(4) 938-949   Apr 2012   [Refereed]
Fujita K, Iwasaki M, Ochi H, Fukuda T, Ma C, Miyamoto T, Takitani K, Negishi-Koga T, Sunamura S, Kodama T, Takayanagi H, Tamai H, Kato S, Arai H, Shinomiya K, Itoh H, Okawa A, Takeda S
Nature medicine   18(4) 589-594   Mar 2012   [Refereed]
Iwasaki M, Piao J, Kimura A, Sato S, Inose H, Ochi H, Asou Y, Shinomiya K, Okawa A, Takeda S
PloS one   7(8) e43372   2012   [Refereed]
Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, Wang K, Rittling S, Nakamoto T, Kaneko K, Kurosawa H, Karsenty G, Denhardt DT, Vilardaga JP, Noda M
Proceedings of the National Academy of Sciences of the United States of America   108(43) 17767-17772   Oct 2011   [Refereed]
Ogata N, Shinoda Y, Wettschureck N, Offermanns S, Takeda S, Nakamura K, Segre GV, Chung UI, Kawaguchi H
The Journal of biological chemistry   286(15) 13733-13740   Apr 2011   [Refereed]
Meguro S, Tomita M, Katsuki T, Kato K, Oh H, Ainai A, Ito R, Takeda S, Kawai T, Atsumi Y, Itoh H, Hasegawa H
International journal of endocrinology   2011 362981   2011   [Refereed]
Sato T, Chida D, Iwata T, Usui M, Hatori K, Abe T, Takeda S, Yoda T
Biomolecular concepts   1(5-6) 357-366   Dec 2010   [Refereed]
Nishikawa K, Nakashima T, Takeda S, Isogai M, Hamada M, Kimura A, Kodama T, Yamaguchi A, Owen MJ, Takahashi S, Takayanagi H
The Journal of clinical investigation   120(10) 3455-3465   Oct 2010   [Refereed]
Itoh T, Takeda S, Akao Y
The Journal of biological chemistry   285(36) 27745-27752   Sep 2010   [Refereed]
Kimura A, Inose H, Yano F, Fujita K, Ikeda T, Sato S, Iwasaki M, Jinno T, Ae K, Fukumoto S, Takeuchi Y, Itoh H, Imamura T, Kawaguchi H, Chung UI, Martin JF, Iseki S, Shinomiya K, Takeda S
Development (Cambridge, England)   137(7) 1159-1167   Apr 2010   [Refereed]
Skeletal Regulation of Energy Metabolism
TAKEDA Shu
Bone and Development in Topic in Bone Biology   267-278   2010   [Refereed]
Tanaka M, Suganami T, Sugita S, Shimoda Y, Kasahara M, Aoe S, Takeya M, Takeda S, Kamei Y, Ogawa Y
Endocrine journal   57(1) 61-72   2010   [Refereed]
Inose H, Ochi H, Kimura A, Fujita K, Xu R, Sato S, Iwasaki M, Sunamura S, Takeuchi Y, Fukumoto S, Saito K, Nakamura T, Siomi H, Ito H, Arai Y, Shinomiya K, Takeda S
Proceedings of the National Academy of Sciences of the United States of America   106(49) 20794-20799   Dec 2009   [Refereed]
Suzuki D, Yamada A, Amano T, Yasuhara R, Kimura A, Sakahara M, Tsumaki N, Takeda S, Tamura M, Nakamura M, Wada N, Nohno T, Shiroishi T, Aiba A, Kamijo R
Developmental biology   335(2) 396-406   Nov 2009   [Refereed]
Takeda S
The international journal of biochemistry & cell biology   41(3) 455-459   Mar 2009   [Refereed]
Tominaga H, Maeda S, Hayashi M, Takeda S, Akira S, Komiya S, Nakamura T, Akiyama H, Imamura T
Molecular biology of the cell   19(12) 5373-5386   Dec 2008   [Refereed]
Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S
Arthritis and rheumatism   58(9) 2764-2775   Sep 2008   [Refereed]
Takeda S
Journal of neuroendocrinology   20(6) 802-807   Jun 2008   [Refereed]
Takeda S, Karsenty G
Bone   42(5) 837-840   May 2008   [Refereed]
Nojiri Y, Takeda S, Enomoto M, Nishitsuji H, Masuda T, Sotome S, Shinomiya K
Journal of medical and dental sciences   55(1) 121-128   Mar 2008   [Refereed]
TAKEDA Shu, Ducy, P
Principle of Bone Biology   1059-1068   2008   [Refereed]
Sato S, Hanada R, Kimura A, Abe T, Matsumoto T, Iwasaki M, Inose H, Ida T, Mieda M, Takeuchi Y, Fukumoto S, Fujita T, Kato S, Kangawa K, Kojima M, Shinomiya K, Takeda S
Nature medicine   13(10) 1234-1240   Oct 2007   [Refereed]
Nakamura T, Imai Y, Matsumoto T, Sato S, Takeuchi K, Igarashi K, Harada Y, Azuma Y, Krust A, Yamamoto Y, Nishina H, Takeda S, Takayanagi H, Metzger D, Kanno J, Takaoka K, Martin TJ, Chambon P, Kato S
Cell   130(5) 811-823   Sep 2007   [Refereed]
Okuda N, Takeda S, Shinomiya K, Muneta T, Itoh S, Noda M, Asou Y
Bone   40(2) 281-292   Feb 2007   [Refereed]
Leptin and bone, in Leptin,
TAKEDA Shu
Springer   1059-1068   2007   [Refereed]
Ito N, Fukumoto S, Takeuchi Y, Takeda S, Suzuki H, Yamashita T, Fujita T
Journal of bone and mineral metabolism   25(6) 419-422   2007   [Refereed]
Kamekura S, Kawasaki Y, Hoshi K, Shimoaka T, Chikuda H, Maruyama Z, Komori T, Sato S, Takeda S, Karsenty G, Nakamura K, Chung UI, Kawaguchi H
Arthritis and rheumatism   54(8) 2462-2470   Aug 2006   [Refereed]
Kondo H, Nifuji A, Takeda S, Ezura Y, Rittling SR, Denhardt DT, Nakashima K, Karsenty G, Noda M
The Journal of biological chemistry   280(34) 30192-30200   Aug 2005   [Refereed]
Fukushima N, Hanada R, Teranishi H, Fukue Y, Tachibana T, Ishikawa H, Takeda S, Takeuchi Y, Fukumoto S, Kangawa K, Nagata K, Kojima M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research   20(5) 790-798   May 2005   [Refereed]
Takeda S
Biochemical and biophysical research communications   328(3) 697-699   Mar 2005   [Refereed]
Elefteriou F, Ahn JD, Takeda S, Starbuck M, Yang X, Liu X, Kondo H, Richards WG, Bannon TW, Noda M, Clement K, Vaisse C, Karsenty G
Nature   434(7032) 514-520   Mar 2005   [Refereed]
Elefteriou F, Takeda S, Ebihara K, Magre J, Patano N, Kim CA, Ogawa Y, Liu X, Ware SM, Craigen WJ, Robert JJ, Vinson C, Nakao K, Capeau J, Karsenty G
Proceedings of the National Academy of Sciences of the United States of America   101(9) 3258-3263   Mar 2004   [Refereed]
Elefteriou F, Takeda S, Liu X, Armstrong D, Karsenty G
Endocrinology   144(9) 3842-3847   Sep 2003   [Refereed]
Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R
The Journal of cell biology   162(1) 139-148   Jul 2003   [Refereed]
Takeda S, Elefteriou F, Karsenty G
Annual review of nutrition   23 403-411   2003   [Refereed]
Takeuchi Y, Watanabe S, Ishii G, Takeda S, Nakayama K, Fukumoto S, Kaneta Y, Inoue D, Matsumoto T, Harigaya K, Fujita T
The Journal of biological chemistry   277(50) 49011-49018   Dec 2002   [Refereed]
Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, Parker KL, Armstrong D, Ducy P, Karsenty G
Cell   111(3) 305-317   Nov 2002   [Refereed]
Shimada T, Mizutani S, Muto T, Yoneya T, Hino R, Takeda S, Takeuchi Y, Fujita T, Fukumoto S, Yamashita T
Proceedings of the National Academy of Sciences of the United States of America   98(11) 6500-6505   May 2001   [Refereed]
Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G
Genes & development   15(4) 467-481   Feb 2001   [Refereed]
Takeda S, Karsenty G
Journal of bone and mineral metabolism   19(3) 195-198   2001   [Refereed]
Amling M, Takeda S, Karsenty G
BioEssays : news and reviews in molecular, cellular and developmental biology   22(11) 970-975   Nov 2000   [Refereed]
Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G
Cell   100(2) 197-207   Jan 2000   [Refereed]
Chikatsu N, Fukumoto S, Suzawa M, Tanaka Y, Takeuchi Y, Takeda S, Tamura Y, Matsumoto T, Fujita T
Clinical endocrinology   50(4) 537-543   Apr 1999   [Refereed]
Takeda S, Yoshizawa T, Nagai Y, Yamato H, Fukumoto S, Sekine K, Kato S, Matsumoto T, Fujita T
Endocrinology   140(2) 1005-1008   Feb 1999   [Refereed]
Yoshizawa T, Handa Y, Uematsu Y, Takeda S, Sekine K, Yoshihara Y, Kawakami T, Arioka K, Sato H, Uchiyama Y, Masushige S, Fukamizu A, Matsumoto T, Kato S
Nature genetics   16(4) 391-396   Aug 1997   [Refereed]
Nakayama K, Fukumoto S, Takeda S, Takeuchi Y, Ishikawa T, Miura M, Hata K, Hane M, Tamura Y, Tanaka Y, Kitaoka M, Obara T, Ogata E, Matsumoto T
The Journal of clinical endocrinology and metabolism   81(2) 607-611   Feb 1996   [Refereed]

Misc

 
Bone and Calcium Research Update 2015. Metabolic crosstalk bone and other organs.
Hiroki Ochi, Shu Takeda
Clin Calcium   25(1) 11-20   Jan 2015
Bone homeostasis is maintained by bone formation and bone resorption. The identification that nervous system controls bone metabolism through leptin deficient mice studies opened a new field in bone biology. Notably, sympathetic and parasympatheti...
Frontiers in Live Bone Imaging Researches. Functional cross talk between bone and nervous system.
Toru Fukuda, Shu Takeda
Clin Calcium   25(6) 891-898   2015
Bone homeostasis is maintained by bone formation and bone resorption. The traditional view of bone metabolism as a primarily endocrine regulation has been expanded in recent years following the identification of nervous system controlling bone met...
Updates on Lifestyle-Related Diseases and Bone Metabolism. Bidirectional relationship between lifestyle-related diseases and bone metabolism.
Shingo Sato, Shu Takeda
Clin Calcium   24(11) 1591-1598   Nov 2014
Lifestyle-related diseases such as diabetes mellitus, chronic kidney disease, and hypertension were previously considered to be unrelated to osteoporosis. However, recent investigations have demonstrated that lifestyle-related diseases have a sign...
Regulation of bone metastasis by microRNAs.
Shingo Sato, Shu Takeda
Clin Calcium   24(8) 1209-1215   Aug 2014
Bone metastasis is a common complication in patients with advanced cancer. It can increase the risk of severe pain, pathological fracture, and spinal cord compression, which make physical activity remarkably worse. Identification of the molecular ...
Bone metabolism and cardiovascular function update. Nerve system and mutual interaction between bone and blood vessel.
Hiroki Ochi, Shu Takeda
Clin Calcium   24(7) 77-83   Jul 2014
The identification that nervous system controls bone metabolism through leptin deficient mice studies opened a new field in bone biology. Notably, sympathetic and parasympathetic nerve system regulate bone metabolism. In addition, sensory nerve sy...

Conference Activities & Talks

 
Establishment of medical and dental combined treatment system for cancer patients with bone metastasis
Sato S, Sawamura C, Matsumoto S, Takeda S, Okawa A
The 48th Annual Musculoskeletal Tumor Meeting of the Japanese Orthopaedic Association   10 Jul 2015   
Microarray and RNA sequencing analysis of pericyte-derived sarcomas in a novel sarcoma mouse model
Shingo Sato, Qingxia Wei, Makoto Hirata, Yuning Tang, Shu Takeda, Jay S. Wunder, Benjamin Alman
Connective Tissue Oncology Society Meeting 2014   17 Oct 2014   
The gene expression analysis of mouse sarcomas developed in our novel mouse model and identification of neoplastic changes in pericytes
Shingo Sato, Qingxia Wei, Makoto Hirata, Jackie Tang, Seiichi Matsumoto, Atsushi Okawa, Shu Takeda, Benjamin Alman
The 29th Annual Research Meeting of the Japanese Orthopaedic Association   10 Oct 2014