論文

査読有り
2009年4月

Alkalization of blood pH is responsible for survival of cancer patients by mild hyperthermia

BIOMEDICAL RESEARCH-TOKYO
  • Takahiko Ohishi
  • ,
  • Chiyoko Nukuzuma
  • ,
  • Akira Seki
  • ,
  • Mayumi Watanabe
  • ,
  • Chikako Tomiyama-Miyaji
  • ,
  • Eisuke Kainuma
  • ,
  • Masashi Inoue
  • ,
  • Yuh Kuwano
  • ,
  • Toru Abo

30
2
開始ページ
95
終了ページ
100
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2220/biomedres.30.95
出版者・発行元
BIOMEDICAL RESEARCH PRESS LTD

The effect of mild hyperthermia on venous blood pH was examined in 6 cancer patients. Mild hyperthermia was induced by continuation of a rectal temperature of 39.5 degrees C for 30 min. All 6 patients were diagnosed as suffering from advanced cancer with or without surgery and chemotherapy pretreatrnents. In Cases I to 5, but not Case 6, venous blood pH was alkalized up to pH 7.7 by this mild hyperthermia and the effect was reproduced depending on the application of hyperthermia. At this time, alkalized pH was accompanied by increased PO, and decreased PCO(2) in the blood. These patients showed good physical conditions and improved clinical data. On the other hand, hyperthermia could not be continued in Case 6 due to his worsened physical condition. The present data suggest that mild hyperthermia is a useful method to improve circulation failure, physical condition and clinical data.

リンク情報
DOI
https://doi.org/10.2220/biomedres.30.95
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000265572900004&DestApp=WOS_CPL
ID情報
  • DOI : 10.2220/biomedres.30.95
  • ISSN : 0388-6107
  • Web of Science ID : WOS:000265572900004

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