Gota Kawai

J-GLOBAL         Last updated: Nov 5, 2019 at 02:40
 
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Name
Gota Kawai
E-mail
gota.kawaip.chibakoudai.jp
URL
http://www.lifescience.it-chiba.ac.jp/kawai/index.html
Affiliation
Chiba Institute of Technology
Section
Faculty of Advanced Engineering, Department of Life Science
Research funding number
70211860

Research Interests

 
 

Research Areas

 
 

Committee Memberships

 
Jan 2010
   
 
The Japanese Society of Polyamine Research  Councilor
 

Published Papers

 
Impact of 5'-end nucleotide modifications of HIV-1 genomic RNA on reverse transcription
Huang, Y.-L., Kawai, G., Hasegawa, A., Kannagi, M. and Masuda, T.,
Biophysical Research Communications   516(4) 1145-1151   Sep 2019   [Refereed]
Crystal structure of the flavin-dependent thymidylate synthase Thy1 from Thermus thermophilus with an extra C-terminal domain
Ogawa, A., Sampei, G. and Kawai, G.
Acta Crystallographica Section F   75 450-454   Jun 2019   [Refereed]
Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136–BzDANP–Dicer
Otabe, T., Nagano, K., Kawai, G., Murata, A., Nakatani,
Bioorganic & Medicinal Chemistry   27 2140-2148   May 2019   [Refereed]
Distinct RNA recognition mechanisms in closely related LINEs from zebrafish
Otsu, M. and Kawai, G.
Nucleosides, Nucleotides, and Nucleic Acids   38(4) 294-304   Apr 2019   [Refereed]
Synthesis of a protected ribonucleoside phosphoramidite-linked spin label via an alkynyl chain at the 5' position of uridine
Hatano, A., Terado, N., Kanno, Y., Nakamura, T. and Kawai, G.
Synthetic Communications   49(1) 136-145   2019   [Refereed]
New, spin-labeled nucleosides, and an efficient synthetic route for a modified uridine amidite, were developed. The electron paramagnetic resonance (EPR) data revealed a nitroxyl radical in the structure of synthetic nucleoside compounds; however...

Books etc

 
Essential Structural Biology
Gota Kawai, Taiichi Sakamoto, Naoki Nemoto (Part:Joint Work, Chapters 1, 4.3, 5)
Kodansha   Feb 2018   
In the first half, the structures of protein and nucleic acids and those relation to the function are described and, in the second half, methods to analyze the molecular structures are introduced.
Experimental Approaches of NMR spectroscopy
Taiichi Sakamoto, Maina Otsu and Gota Kawai (Part:Joint Work, Chapter 16 NMR Studies on RNA pp439-459)
Springer   Jan 2018   
Basic methods for NMR analysis of RNA are presented for researchers who recently joined or want to join this field.

Conference Activities & Talks

 
A Monomeric Form of the Isolated dimerization Initiation Site of HIV-1 Genome
Takasu, A., Takahashi, K., Baba, S., Chattopadhyay, P., Kimitsuna, W., Koyanagi, Y., Yamamoto, N., Takaku, H. and Kawai, G.
18th International conference on magnetic resoance in biological systems.   Aug 1998   
Conformational Analysis of an RNA Pseudoknot in tmRNA Required for Trans Translation
Nameki, N., Kawai, G., Mimeno, H., and Muto, A.
18th International conference on magnetic resoance in biological systems.   Aug 1998   
Interactions of U6 snRNA with Influenza virus NS1 protein
Hosono, K., Someya, T., Kawai, G., Takai, K., Nakada, S., Takaku, H.
18th International conference on magnetic resoance in biological systems.   Aug 1998   
Site Specific Cleavage of RNA by Non-Ionic Detergent and Monovalent Cation
Shirakura, H., Itoh, M., Hosono, K., Takai, K., Kawai, G., Takaku, H.
18th International conference on magnetic resoance in biological systems.   Aug 1998   
Structure of TandemG:A Pairs in an RNA 28MER Which Contains a Sequence of the Enzyme Compornent of a Hammerhead Ribozyme System
Sakamoto, T., Kawai, G., Katahira, M., Kim, M. H., Tanaka, Y., Kurihara, Y., Kohno, T., Watanabe, S., Yokoyama, S., Watanabe, K., and Uesugi, S.
18th International conference on magnetic resoance in biological systems.   Aug 1998   

Research Grants & Projects

 
Structural biology of RNA
Project Year: Jun 1997 - Mar 2002
Discovery and application of functional non-coding RNAs
Project Year: Jun 2002 - Mar 2005
Functional analysis of proteins from thermophiles
Project Year: Jul 2002 - Mar 2006

Patents

 
US2006051804 : Oligonucleotides labeled with Stable Isotopes and Method for detecting the same
7,038,036 : Oligonucleotides labeled with Stable Isotopes and Method for detecting the same