大河内仁志 (Hitoshi Okochi) - マイポータル

基本情報

J-GLOBAL ID: 200901068617745390
researchmap会員ID: 5000101011

研究キーワード

研究分野

ライフサイエンス / 皮膚科学 / 糖尿病

論文

Encapsulated human islets in alginate fiber maintain long-term functionality.

Nishida J., Tsuno T., Yabe SG, Kin T., Fukuda S., Takeda F., Shirakawa J., Okochi H.

Endocr J 71(3) 253-264 2024年査読有り最終著者
Establishment of human induced pluripotent stem cell-derived hepatobiliary organoid with bile duct for pharmaceutical research use.

Wang L., Koui Y., Kanegae K., Kido T., Tamura-Nakano M., Yabe SG, Tai K., Nakajima Y., Kusuhara H., Sakai Y. …

Biomaterials 310 2024年査読有り
Autologous Angiogenic Therapy with Cultured Mesenchymal Stromal Cells in Platelet-Rich Plasma for Critical Limb Ischemia.

Fukuda S., Hagiwara S., Okochi H., Ishiura N., Nishibe T., Yakabe R., Suzuki H.

Reg Ther 24 472-478 2023年査読有り
The Functional Maturity of Grafted Human Pluripotent Stem Cell Derived-Islets (hSC-Islets) Evaluated by the Glycemic Set Point during Blood Glucose Normalizing Process in Diabetic Mice.

Yabe SG, Fukuda S., Nishida J., Takeda F., Okochi H.

Heliyon 2023年査読有り最終著者
Generation of Angiotensin-Converting Enzyme 2/Transmembrane Protease Serine 2-Double-Positive Human Induced Pluripotent Stem Cell-Derived Spheroids for Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Drug Evaluation

Higashi-Kuwata N., Yabe SG, Fukuda S., Nishida J., Tamura-Nakano M., Hattori SI, Okochi H., Mitsuya H.

Microbiol Spectr. 2022年10月
Lymphatic dysfunction exacerbates cutaneous tumorigenesis and psoriasis-like skin inflammation through accumulation of inflammatory cytokines.

Boki H., Kimura T., Miyagaki T., Suga H., Blauvelt A., Okochi H., Sato S., Sugaya M.

J Invest Dermatol 142(6) 1692-1702 2022年査読有り
TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo.

Ikeda M., Yabe SG, Kiso M., Ishiguro N., Tsunemi Y., Okochi H.

J Dermatol Sci 106 78-85 2022年査読有り最終著者
Efficient induction of pancreatic alpha cells from human induced pluripotent stem cells by controlling the timing for BMP antagonism and activation of retinoic acid signaling.

Yabe SG, Fukuda S., Nishida J., Takeda F., Nashiro K., Okochi H.

PLOS One 16(1) 2021年1月査読有り最終著者
Lotus-root-shaped cell-encapsulated construct as a retrieval graft for long-term transplantation of human iPSC-derived β-cells.

Ozawa F., Nagata S., Oda H., Yabe SG, Okochi H., Takeuchi S.

iScience 24 2020年査読有り
The intraperitoneal space is more favorable than the subcutaneous one for transplanting alginate fiber containing iPS-derived islet-like cells.

Satsuki Fukuda, Shigeharu G Yabe, Junko Nishida, Fujie Takeda, Kiyoko Nashiro, Hitoshi Okochi

Regenerative therapy 11 65-72 2019年12月査読有り最終著者
Induction of functional islet-like cells from human iPS cells by suspension culture.

Shigeharu G Yabe, Satsuki Fukuda, Junko Nishida, Fujie Takeda, Kiyoko Nashiro, Hitoshi Okochi

Regenerative therapy 10 69-76 2019年6月査読有り最終著者
Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells.

Shigeharu G Yabe, Junko Nishida, Satsuki Fukuda, Fujie Takeda, Kiyoko Nasiro, Kazuki Yasuda, Naoko Iwasaki, Hitoshi Okochi

PloS one 14(5) e0217110 2019年査読有り最終著者
Characterization of Peribiliary Gland-Constituting Cells Based on Differential Expression of Trophoblast Cell Surface Protein 2 in Biliary Tract.

Satoshi Matsui, Kenichi Harada, Naoko Miyata, Hitoshi Okochi, Atsushi Miyajima, Minoru Tanaka

The American journal of pathology 188(9) 2059-2073 2018年9月査読有り
Differential expression of Lutheran/BCAM regulates biliary tissue remodeling in ductular reaction during liver regeneration.

Yasushi Miura, Satoshi Matsui, Naoko Miyata, Kenichi Harada, Yamato Kikkawa, Masaki Ohmuraya, Kimi Araki, Shinya Tsurusaki, Hitoshi Okochi, Nobuhito Goda …

eLife 7 2018年7月30日
Introduction of the TERT and BMI1 genes into murine dermal papilla cells ameliorates hair inductive activity.

Masahiro Kiso, Shigeharu Yabe, Munenari Itoh, Hidemi Nakagawa, Hitoshi Okochi

Journal of dermatological science 90(2) 218-221 2018年5月査読有り最終著者
Oncostatin M causes liver fibrosis by regulating cooperation between hepatic stellate cells and macrophages in mice.

Matsuda M., Tsurusaki S., Miyata N., Saijou E., Okochi H., Miyajima A., Tanaka M.

Hepatology 67 296-312 2018年査読有り
Human iPS-derived spheroids in suspension culture express developmental stage specific genes toward definitive endoderm differentiation earlier than adherent cells.

Yabe SG, Nishida J., Fukuda S., Takeda F., Nashiro K., Ibuki M., Okochi H.

Int J Dev Biol 63 271-280 2018年査読有り最終著者
Efficient generation of functional pancreatic β-cells from human induced pluripotent stem cells.

Shigeharu G Yabe, Satsuki Fukuda, Fujie Takeda, Kiyoko Nashiro, Masayuki Shimoda, Hitoshi Okochi

Journal of diabetes 9(2) 168-179 2017年2月査読有り最終著者
膵臓と膵島

大河内仁志, 矢部茂治, 霜田雅之

移植 52(4) 325-331 2017年査読有り筆頭著者
再生医療と移植医療の新展開 iPS細胞を用いた次世代型膵島移植療法の開発

霜田雅之, 矢部茂治, 篠原孝也, 元文姫, 福田沙月, 渡邊亜美, 渡邊貴一, 篠原満利恵, 井上貴史, 伊吹将人 …

糖尿病 59(Suppl.1) S-106 2016年4月査読有り

もっとみる

MISC

Endodermal differentiation of human induced pluripotent stem cells using simple dialysis culture system in suspension culture.

Marie Shinohara, Hyunjin Choi, Masato Ibuki, Shigeharu G Yabe, Hitoshi Okochi, Atsushi Miyajima, Yasuyuki Sakai

Regenerative therapy 12 14-19 2019年12月15日
Suppressive Effects of Mesenchymal Stem Cells in Adipose Tissue on Allergic Contact Dermatitis.

Sota Kikuchi, Koichi Yanaba, Yoshimasa Nobeyama, Shigeharu Yabe, Masahiro Kiso, Hidehisa Saeki, Yayoi Tada, Hidemi Nakagawa, Hitoshi Okochi

Annals of dermatology 29(4) 391-399 2017年8月
Efficiently differentiating vascular endothelial cells from adipose tissue-derived mesenchymal stem cells in serum-free culture.

Masamitsu Konno, Tatsuo S Hamazaki, Satsuki Fukuda, Makoto Tokuhara, Hideho Uchiyama, Hitoshi Okazawa, Hitoshi Okochi, Makoto Asashima

Biochemical and biophysical research communications 400(4) 461-5 2010年10月1日
Pdx1-transfected adipose tissue-derived stem cells differentiate into insulin-producing cells in vivo and reduce hyperglycemia in diabetic mice.

Hiromitsu Kajiyama, Tatsuo S Hamazaki, Makoto Tokuhara, Shinji Masui, Koji Okabayashi, Kiyoshi Ohnuma, Shigeharu Yabe, Kazuki Yasuda, Shoichi Ishiura, Hitoshi Okochi …

The International journal of developmental biology 54(4) 699-705 2010年

共同研究・競争的資金等の研究課題

皮膚の幹細胞研究と再生医療への応用

大河内仁志

基本情報

研究キーワード

研究分野

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

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