MIZUMOTO Shuji

J-GLOBAL         Last updated: Apr 30, 2019 at 17:41
 
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Name
MIZUMOTO Shuji
E-mail
mizumotomeijo-u.ac.jp
Affiliation
Meijo University
Section
Faculty of Pharmacy
Job title
Associate Professor

Research Areas

 
 

Academic & Professional Experience

 
Apr 2019
 - 
Today
Associate Professor, Faculty of Pharmacy, Meijo University
 
Apr 2017
 - 
Mar 2018
Visiting Researcher, Department of Women’s and Children’s Health, Clinical Genetics Group (Stephen Robertson’s Lab), University of Otago, Dunedin School of Medicine,
 
 
   
 
HOKKAIDO UNIVERSITY
 
 
   
 
Faculty of Advanced Life Science
 
 
   
 
Laboratory of Proteoglycan Signaling and Therapeutics
 

Education

 
 
 - 
2006
Graduate School, Division of Pharmaceutical Sciences, Kobe Pharmaceutical University
 
 
 - 
2001
Faculty of Pharmaceutical Science, Kobe Pharmaceutical University
 

Committee Memberships

 
 
   
 
Trends in Glycoscience and Glycotechnology, Glycotopic Reporter
 

Awards & Honors

 
Sep 2016
Glycobiological approaches for bone and skin disorders caused by deficiency of glycosaminoglycans and its role for tumor metastasis, Research Award for Japanese Society of Carbohydrate Research, The Japanese Society of Carbohydrate Research
Winner: Shuji Mizumoto
 
Aug 2015
Travel Award, 9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
 

Published Papers

 
Compositional analysis of the glycosaminoglycan family in velvet antlers of Sika deer (Cervus nippon) at different growing stages
Naoko Takeda-Okuda, Shuji Mizumoto, Zui Zhang, Soo-Ki Kim, Chi-Ho Lee, Byong-Tae Jeon, Yoshinao Z. Hosaka, Kenji Kadomatsu, Shuhei Yamada, and Jun-ichi Tamura
Glycoconjugate Journal   36(2) 127-139   Apr 2019   [Refereed]
Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with mcEDS-CHST14
Takuya Hirose, Naoki Takahashi, Prasarn Tangkawattana, Jun Minaguchi, Shuji Mizumoto, Shuhei Yamada, Noriko Miyake, Shujiro Hayashi, Atsushi Hatamochi, Jun Nakayama, Tomomi Yamaguchi, Ayana Hashimoto, Yoshihiro Nomura, Kazushige Takehana, Tomoki Kosho, and Takafumi Watanabe
Biochimica et Biophysica Acta (BBA) - General Subjects   1863(3) 623-631   Mar 2019   [Refereed]
Identification of Novel LFNG Mutations in Spondylocostal Dysostosis
Nao Otomo, Shuji Mizumoto, Hsing-Fang Lu, Kazuki Takeda, Belinda Campos-Xavier, Lauréane Mittaz-Crettol, Long Guo, Kazuharu Takikawa, Masaya Nakamura, Shuhei Yamada, Morio Matsumoto, Kota Watanabe, Shiro Ikegawa
Journal of Human Genetics   in press    Dec 2018   [Refereed]
Screening of known disease genes in congenital scoliosis
Kazuki Takeda, Ikuyo Kou, Shuji Mizumoto, Shuhei Yamada, Noriaki Kawakami, Masahiro Nakajima, Nao Otomo, Yoji Ogura, Noriko Miyake, Naomichi Matsumoto, Toshiaki Kotani, Hideki Sudo, Ikuho Yonezawa, Koki Uno, Hiroshi Taneichi, Kei Watanabe, Hideki Shigematsu, Ryo Sugawara, Yuki Taniguchi, Shohei Minami, Masaya Nakamura, Morio Matsumoto, Japan Early Onset Scoliosis Research Group, Kota Watanabe, and Shiro Ikegawa
Molecular Genetics & Genomic Medicine   6(6) 966-974   Nov 2018   [Refereed]
Fumihiko Nagano, Tomohiro Mizuno, Shuji Mizumoto, Kengo Yoshioka, Kazuo Takahashi, Naotake Tsuboi, Shoichi Maruyama, Shuhei Yamada, and Tadashi Nagamatsu
European Journal of Pharmacology   826 48-55   May 2018   [Refereed]
Shuji Mizumoto
Trends in Glycoscience and Glycotechnology   30(174) E67-E89   May 2018   [Refereed][Invited]
Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica
Wing Lee Chan, Magdalena Steiner, Tomasz Witkos, Johannes Egerer, Björn Busse, Shuji Mizumoto, Jan M. Pestka, Haikuo Zhang, Ingrid Hausser, Layal Abo Khayal, Claus-Eric Ott, Mateusz Kolanczyk, Bettina Willie, Thorsten Schinke, Chiara Paganini, Antonio Rossi, Kazuyuki Sugahara, Michael Amling, Petra Knaus, Danny Chan, Martin Lowe, Stefan Mundlos, Uwe Kornak
PLoS Genetics   14(3) e1007242   Mar 2018   [Refereed]
Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency
Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, and Tomoki Kosho
Glycobiology   28(2) 80-89   Feb 2018   [Refereed]
The reduction of heparan sulphate in the glomerular basement membrane does not augment urinary albumin excretion
Satoshi Aoki, Akiko Saito-Hakoda, Takeo Yoshikawa, Kyoko Shimizu, Kiyomi Kisu, Susumu Suzuki, Kiyoshi Takagi, Shuji Mizumoto, Shuhei Yamada, Toin H. van Kuppevelt, Atsushi Yokoyama, Taiji Matsusaka, Hiroshi Sato, Sadayoshi Ito, Akira Sugawara
Nephrology Dialysis Transplantation   33(1) 26-33   Jan 2018   [Refereed]
Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus
Yusuke Mii, Takayoshi Yamamoto, Ritsuko Takada, Shuji Mizumoto, Makoto Matsuyama, Shuhei Yamada, Shinji Takada and Masanori Taira
Nature Communications   8(1) 1973   Dec 2017   [Refereed]
*Long Guo, *Nursel H Elcioglu, *Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa (equal contribution)
Journal of Human Genetics   62(8) 797-801   Aug 2017   [Refereed]
*Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Shuhei Yamada, and *Kazuyuki Sugahara (*corresponding author)
Clinical Biochemistry   50(12) 670-677   Aug 2017   [Refereed]
Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders
Shuji Mizumoto*, Tomoki Kosho, Shuhei Yamada, and Kazuyuki Sugahara* (*corresponding author)
Pharmaceuticals   10(2) e34   Mar 2017   [Refereed][Invited]
Julia Vodopiutz, Shuji Mizumoto, Ekkehard Lausch, Antonio Rossi, Sheila Unger, Nikolaus Janocha, Rainer Seidl, Susanne Greber-Platzer, Shuhei Yamada, Thomas Müller, Bernd Jilma, Rudolf Ganger, Andrea Superti-Furga, Shiro Ikegawa, Kazuyuki Sugahara, Andreas R. Janecke
Human Mutation   38(1) 34-38   Jan 2017   [Refereed]
*Florian Job, *Shuji Mizumoto, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saal4, Melanie Patterson5, Margaret I. Gibson5, Sarah Soden6, Neil Miller7, Isabelle Thiffault5, Carol Saunders5, Shuhei Yamada, Katrin Hoffmann, Kazuyuki Sugahara, Emily Farrow. (*equal contribution)
BMC Medical Genetics   17(1) 86   Nov 2016   [Refereed]
Kenji Suzuki, Somasundaram Arumugam, Junji Yokoyama, Yusuke Kawauchi, Yutaka Honda, Hiroki Sato, Yutaka Aoyagi, Shuji Terai, Kazuichi Okazaki, Yasuo Suzuki, Shuji Mizumoto, Kazuyuki Sugahara, Raja Atreya, Markus F. Neurath, Kenichi Watanabe, Taishi Hashiguchi, Hiroyuki Yoneyama, Hitoshi Asakura
PLoS ONE   11(7) e0158967   Jul 2016   [Refereed]
*Birgit S. Budde, *Shuji Mizumoto, Ryo Kogawa, Christian Becker, Janine Altmüller, Holger Thiele, Franz Rüschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hämmerle, Wolffang Höhne, Kazuyuki Sugahara, Peter Nürnberg, Ingo Kennerknecht. (*equal contribution)
Human Genetics   134(7) 691-704   Jul 2015   [Refereed]
Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
Current Opinion in Structural Biology   34 35-42   Jul 2015   [Refereed][Invited]
Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
BioMed Research International   2015 article ID 861752   Jul 2015   [Refereed][Invited]
Marina Koutsioumpa, Evangelia Poimenidi, Evangelia Pantazaka, Christina Theodoropoulou, Angeliki Skoura, Vasileios Megalooikonomou, Nelly Kieffer, Jose Courty, Shuji Mizumoto, Kazuyuki Sugahara, and Evangelia Papadimitriou
Molecular Cancer   14(1) 19   Feb 2015   [Refereed]
Daisuke Kawamura, Tadanao Funakoshi, Shuji Mizumoto, Kazuyuki Sugahara, and Norimasa Iwasaki
Journal of Orthopaedic Science   in 19(6) 1028-1035   Nov 2014   [Refereed]
Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
BioMed Research International   2014 article ID 495764   Jul 2014   [Refereed][Invited]
Peraphan Pothacharoen, Sumet Najarus, Jongkolnee Settakorn, Shuji Mizumoto, Kazuyuki Sugahara, and Prachya Kongtawelert
Glycoconjugate Journal   31(3) 221-230   Apr 2014   [Refereed]
Yu Zhao, Tasuku Nakajima, Jing Jing Yang, Takayuki Kurokawa, Jian Liu, Jishun Lu, Shuji Mizumoto, Kazuyuki Sugahara, Nobuto Kitamura, Kazunori Yasuda, A.U. Dan Daniels, Jian Ping Gong
Advanced Materials   26(3) 436-442   Jan 2014   [Refereed]
Hirofumi Kodera, Kazuyuki Nakamura, Hitoshi Osaka, Yoshihiro Maegaki, Kazuhiro Haginoya, Shuji Mizumoto, Mitsuhiro Kato, Nobuhiko Okamoto, Mizue Iai, Yukiko Kondo, Kiyomi Nishiyama, Yoshinori Tsurusaki, Mitsuko Nakashima, Noriko Miyake, Kazuyuki Sugahara, Isao Yuasa, Yoshinao Wada, Naomichi Matsumoto, and Hirotomo Saitsu
Human Mutation   34(12) 1708-1714   Dec 2013   [Refereed]
Aritoshi Iida*, Pelin Ozlem Simsek-Kiper*, Shuji Mizumoto*, Touma Hoshino, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hulya Kayserili, Gulen Eda Unite, Koray Boduroglu, Shigehiko Watanabe, Hirofumi Ohashi, Yasemin Alanay, Kazuyuki Sugahara, Gen Nishimura, and Shiro Ikegawa (*equal contribution)
Human Mutation   34(10) 1381-1386   Oct 2013   [Refereed]
*Thomas Müller, *Shuji Mizumoto, *Indrajit Suresh, Yoshie Komatsu, Julia Vodopiutz, Munis Dündar, Volker Straub, Arno Lingenhel, Andreas Melmer, Silvia Lechner, Johannes Zschocke, Kazuyuki Sugahara, Andreas R Janecke (*equal contribution)
Human Molecular Genetics   22(18) 3761-3772   Sep 2013   [Refereed]
Shuji MIZUMOTO, Duriya FONGMOON, and Kazuyuki SUGAHARA
Glycoconjugate Journal   30(6) 619-632   Aug 2013   [Refereed]
*Masahiro Nakajima, *Shuji Mizumoto, *Noriko Miyake, Ryo Kogawa, Aritoshi Iida, Hironori Ito, Hiroshi Kitoh, Aya Hirayama, Hiroshi Mitsubuchi, Osamu Miyazaki, Rika Kosaki, Reiko Horikawa, Angeline Lai, Roberto Mendoza-Londono, Lucie Dupuis, David Chitayat, Andrew Howard, Gabriela Ferraz-Leal, Denise Cavalcanti, Yoshinori Tsurusaki, Hirotomo Saitsu, Shigehiko Watanabe, Ekkehart Lausch, Sheila Unger, Luisa Bonafé, Hirofumi Ohashi, Andrea Superti-Furga, Naomichi Matsumoto, Kazuyuki Sugahara, Gen Nishimura, and Shiro Ikegawa (*equal contribution)
American Journal of Human Genetics   92(6) 927-934   Jun 2013   [Refereed]
Glycosaminoglycans are functional ligands for Receptor for Advanced Glycation End-products (RAGE) in tumors
Shuji Mizumoto and Kazuyuki Sugahara
FEBS Journal   280(10) 2462-2470   May 2013   [Refereed][Invited]
Shuji Mizumoto, Shiro Ikegawa, and Kazuyuki Sugahara
Journal of Biological Chemistry   288(16) 10953-10961   Apr 2013   [Refereed][Invited]
Shuji MIZUMOTO
Trends in Glycoscience and Glycotechnology   25(142) 87-89   Mar 2013   [Refereed][Invited]
*Shuji Mizumoto, *Saori Murakoshi, *Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, Kazuyuki Sugahara (*equal contribution)
Glycobiology   23(2) 155-168   Feb 2013   [Refereed]
Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis
*Shuji Mizumoto, *Moto Watanabe, Shuhei Yamada, and Kazuyuki Sugahara (*equal contribution)
BioMed Research International   2013 656319   Feb 2013   [Refereed][Invited]
Tomoyuki Kaneiwa, Anzu Miyazaki, Ryo Kogawa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
Journal of Biological Chemistry   287(50) 42119-42128   Dec 2012
Hyaluronidases have strong hydrolytic activity toward chondroitin 4-sulfate comparable with that toward hyaluronan
Tomoko Honda, Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, Shuhei Yamada
Biomolecules   2 549-563   Nov 2012   [Refereed][Invited]
*Shuji MIZUMOTO, *Jun TAKAHASHI, and Kazuyuki SUGAHARA (*equal contribution)
Journal of Biological Chemistry   287(23) 18985-18994   Jun 2012   [Refereed]

Misc

 
Tadahisa Mikami, Shuji Mizumoto, Naohide Kago, Hiroshi Kitagawa, and Kazuyuki Sugahara
Journal of Biological Chemistry   278(38) 36115-36127   2003
Chie Mitsunaga, Tadahisa Mikami, Shuji Mizumoto, Junko Fukuda, and Kazuyuki Sugahara
Journal of Biological Chemistry   281(28) 18942-18952   2006
Hiroki Nakagawa, Yoichiro Hama, Toshihisa Sumi, Su-Chen Li, Karol Maskos, Kittiwan Kalayanamitra, Shuji Mizumoto, Kazuyuki Sugahara, and Yu-The Li
Glycobiology   17(2) 157-164   2006
Anurag Purushothaman, Junko Fukuda, Shuji Mizumoto, Gerdy B. ten Dam, Toin H. van Kuppevelt, Hiroshi Kitagawa, Tadahisa Mikami, and Kazuyuki Sugahara
Journal of Biological Chemistry   282(27) 19442-19452   2007
Christina Malavaki, Shuji Mizumoto, Nikos Karamanos, Kazuyuki Sugahara
Connective Tissue Research   49(3/4) 133-139   2008
Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M Montaño, Shohei Mitani, and Kazuyuki Sugahara
Journal of Biological Chemistry   283(22) 14971-14979   2008
Mirjam H.H. van Roij, Shuji Mizumoto, Shuhei Yamada, Tim Morgan, M.B. Tan-Sindhunata, H. Meijers-Heijboer, J.I.L.M. Verbeke, David Markie, Kazuyuki Sugahara, Stephen P. Robertson
American Journal of Medical Genetics   146A(18) 2376-2384   2008
Fuchuan Li, Gerdy B. ten Dam, Sengottuvelan Murugan, Shuhei Yamada, Taishi Hashiguchi, Shuji Mizumoto, Kayoko Oguri, Minoru Okayama|, Toin H. van Kuppevelt, and Kazuyuki Sugahara
Journal of Biological Chemistry   283(49) 34294-34304   2008
Shuji Mizumoto, Tadahisa Mikami, Daiki Yasunaga, Naoki Kobayashi, Hajime Yamauchi, Ayumi Miyake, Nobuyuki Itoh, Hiroshi Kitagawa, and Kazuyuki Sugahara
Biochemical Journal   419(2) 387-399   2009
Beyhan Tuysuz, Shuji Mizumoto, Kazuyuki Sugahara, Ahmet Çelebi, Stefan Mundlos, Seval Turkmen
Clinical Genetics   75(4) 375-383   2009
Ajaya K Shetty, Takanari Kobayashi, Shuji Mizumoto, Masaki Narumi, Yoshiaki Kudo, Shuhei Yamada, Kazuyuki Sugahara
Carbohydrate Research   344(12) 1526-1532   2009
Shuhei Yamada, Shuji Mizumoto, Kazuyuki Sugahara
Trends in Glycoscience and Glycotechnology   21(119) 149-162   2009
Iwao Takahashi, Naoya Noguchi, Koji Nata, Shuhei Yamada, Tomoyuki Kaneiwa, Shuji Mizumoto, Takayuki Ikeda, Kazushi Sugihara, Masahide Asano, Takeo Yoshikawa, Akiyo Yamauchi, Nausheen Jamal Shervani, Akira Uruno, Ichiro Kato, Michiaki Unno, Kazuyuki Sugahara, Shin Takasawa, Hiroshi Okamoto, Akira Sugawara
Biochemical and Biophysical Research Communications   383(1) 113-118   2009
Taishi Hashiguchi, Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
Glycoconjugate Journal   27(1) 49-60   2010
Chizuru Akatsu, Duriya Fongmoon, Shuji Mizumoto, Jean-Claude Jacquinet, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
Glycoconjugate Journal   27(4) 387-399   2010
Noriko Miyake, Tomoki Kosho, Shuji Mizumoto, Tatsuya Furuichi, Atsushi Hatamochi, Yoji Nagashima, Eiichi Arai, Kazuo Takahashi, Rie Kawamura, Keiko  Wakui, Jun Takahashi, Hiroyuki Kato, Hiroshi Yasui, Tadao Ishida, Hirofumi Ohashi, Gen Nishimura, Masaaki Shiina, Hirotomo Saitsu, Yoshinori Tsurusaki, Hiroshi Doi, Yoshimitsu Fukushima, Shiro Ikegawa, Shuhei Yamada, Kazuyuki Sugahara, Naomichi Matsumoto
Human Mutation   in press    2010
Jun-ichi Tamura, Tomomi Nakamura-Yamamoto, Yuko Nishimura, Shuji Mizumoto, Jun Takahashi, Kazuyuki Sugahara
Carbohydrate Research   345(15) 2115-2123   2010
2
Shuji Mizumoto
Trends in Glycoscience and Glycotechnology   22(127) 256-258   2010
Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, and Kazuyuki Sugahara
Glycobiology   in press    2010
Biochimica et Biophysica Acta (BBA) - General Subjects
Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada, and Kazuyuki Sugahara
Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage   in press    2011
Sevjidmaa Baasanjav, Lihadh Al-Gazali, Taishi Hashiguchi, Shuji Mizumoto, Bjoern Fischer, Denise Horn, Dominik Seelow, Bassam R. Ali, Samir A.A. Aziz, Ruth Langer, Ahmed A.H. Saleh, Christian Becker, Gudrun Nürnberg, Vincent Cantagre, Joseph G. Gleeson, Delphine Gomez, Jean-Baptiste Michel, Sigmar Stricker, Tom H. Lindner, Peter Nürnberg, Kazuyuki Sugahara, Stefan Mundlos, Katrin Hoffmann
American Journal of Human Genetics   89(1) 15-27   2011
Anurag Purushothaman, Douglas R. Hurst, Claudio Pisano, Shuji Mizumoto, Kazuyuki Sugahara, and Ralph D. Sanderson
Journal of Biological Chemistry   in press 
2
Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada, and Kazuyuki Sugahara
Journal of Biological Chemistry   in press    2011

Books etc

 
Proteoglycan linkeropathies caused by defect in glycosaminoglycan-protein linker region
Shuji Mizumoto
Seikagaku   Apr 2017   
Degradation of glycosaminoglycans and proteoglycans
Shuhei Yamada, Shuji Mizumoto, Kazuyuki Sugahara (Part:Joint Work, Handbook of advanced Glycoscience and Glycoengineering)
NTS   Aug 2015   
Heparan Sulfate
Shuji Mizumoto, Kazuyuki Sugahara (Part:Joint Work)
NTS   Aug 2015   
Chondroitin Sulfate
Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada (Part:Joint Work)
Encyclopedia of Polymeric Nanomaterials (Springer-Verlag Berlin Heidelberg), pp. 389-397   Jun 2015   
Carbohydrate (N-acetylgalactosamine 4-O) sulfotransferase 14 (CHST14)
Tomoki Kosho, Shuji Mizumoto, and Kazuyuki Sugahara (Part:Joint Work)
May 2014   
ISCSM2011 Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis
May 2012   
Glycosaminoglycan chain analysis and characterization (Glycosylation/Epimerization)
In Methods in Molecular Biology, “Proteoglycans: Methods and Protocols” Humana Press, Springer,   2011   
Biosynthesis and roles in skin of glycosaminoglycans
In Fragrance Journal   2010   
Heparan sulfate synthases and related genes
In Experimental Glycoscience “Glycobiology” (Taniguchi N., Suzuki A., Ito Y., Narimatsu H., Kawasaki T., Hase S., eds), pp. 59-63, 2008, Springer, Tokyo, Japan   2008   
Heparan sulfate synthase-related genes
Shuji Mizumoto, Hiroshi Kitagawa, and Kazuyuki Sugahara (Part:Joint Work)
Dec 2005   
Biosynthetic pathways for differential expression of functional chondroitin sulfate and heparan sulfate
In Handbook of Carbohydrate Engineering (Kevin J. Yarema, ed.), CRC Press (Taylor & Francis Group), pp. 289-324, 2005, Boca Raton, FL.   2005   
Biosynthesis of Heparin and Heparan sulfate
In Chemistry and Biology of Heparin and Heparan sulfate (Hari G. Garg, Robert J. Linhardt and Charles A. Hales, eds.), pp. 203-243, 2005, Elsevier, Oxford, UK.   2005   

Conference Activities & Talks

 
Musculocontractural Ehlers-Danlos syndrome caused by a CHST14 deficiency results in defect in urinary dermatan sulfate
◯Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Kazuyuki Sugahara, Shuhei Yamada
The International Symposium on the Ehlers-Danlos Syndromes   27 Sep 2018   
A mouse model for gerodermia osteodysplastica, Gorab-null mice, shows a reduction in glycosaminoglycans
Wing Lee Chan, Magdalena Steiner Tomasz Witkos, Johannes Egerer, Björn Busse, ◯Shuji Mizumoto, Jan M. Pestka, Haikuo Zhang, Ingrid Hausser, Layal Abo Khayal, Claus-Eric Ott, Mateusz Kolanczyk, Bettina Willie, Thorsten Schinke, Chiara Paganini, Antonio Rossi, Kazuyuki Sugahara, Michael Amling, Petra Knaus, Danny Chan, Martin Lowe, Stefan Mundlos, Uwe Kornak
The 91st Annual Meeting of Japanese Biochemical Society   24 Sep 2018   
Spondyloepimetaphyseal dysplasia with immune deficiency caused by mutation in EXTL3
◯水本秀二, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak,松本直通, 三宅紀子, 西村玄, 山田修平, 池川志郎
The 37th Annual Meeting of Japanese Carbohydrate Research   30 Aug 2018   
Defects in Biosynthesis of Glycosaminoglycans Cause Hereditary Bone, Skin, Heart, Immune, and Neurological Disorders [Invited]
◯Shuji Mizumoto
National Glycoengineering Research Center (NGRC) Seminar   21 Jun 2018   
A novel type of spondylo-epi-metaphyseal dysplasia with immuno-deficiency caused by mutation in EXTL3 encoding a glycosyltransferase responsible for biosynthesis of heparan sulfate
◯Shuji Mizumoto, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shuhei Yamada, and Shiro Ikegawa
The 11th International Symposium on Glycosyltransferases (GlycoT2018)   19 Jun 2018   
Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins
◯Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok, and Kazuyuki Sugahara
平成28年度 新学術領域「神経糖鎖生物学」最終シンポジウム   3 Mar 2017   
Multiple fractures and severe osteoporosis caused by mutations in a glycosyltransferase responsible for biosynthesis of glycosaminoglycans
27 Sep 2016   
Quantification of dermatan sulfate from urine in Ehlers-Danlos syndrome caused by carbohydrate sulfotransferase 14 (CHST14)/dermatan 4-O-sulfotransferase-1 (D4ST1) deficiency
◯Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Shuhei Yamada, and Kazuyuki Sugahara
XXVIII International Carbohydrate (ICS2016), New Orleans, Loisiana, USA   19 Jul 2016   
Multiple fractures and severe osteoporosis caused by mutations in a glycosyltransferase responsible for biosynthesis of glycosaminoglycans
◯S Mizumoto, F Job, L Smith, N Couser, A Brazil, H Saul, M Patterson, MI Gibson, S Soden, N Miller, I Thiffault, C Saunders, S Yamada, K Hoffman, K Sugahara, E Farrow
The 10th International Symposium on Glycosyltransferases (GlycoT2016), Tronto, Canada   20 Jun 2016   
Detection of the degradation activities of chondroitin sulfate and hyaluronan in mouse brain as well as cultured cell lines
◯Shuji Mizumoto, Tomomasa Yamanaka, Sae Nagai, and Shuhei Yamada
The 3rd International Symposium on Glyco-Neuroscience, Awaji Yumebutai International Conference Center   14 Jan 2016   
Loss-of-function mutation of glucuronyltransferase-I causes skeletal dysplasia in a consanguineous clan from the island of Nias/Indonesia
◯Shuji Mizumoto, Birgit S. Budde, Ryo Kogawa, Christian Becker, Janine Altmüller, Holger Thiele, Franz Rüschendorf, Mohammad R. Toliat, Gerrit Kaleschke, Johannes M. Hämmerle, Wolffang Höhne, Kazuyuki Sugahara, Peter Nürnberg, Ingo Kennerknecht
9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium, Seoul, Korea, ECC, Ewha Womans University   24 Aug 2015   
Spondyloepimetaphyseal dysplasia and Ehlers-Danlos syndrome caused by mutations of glycosaminoglycan biosynthetic enzymes, GalT-II and DS-epimerase
◯Shuji Mizumoto, Masahiro Nakajima, Thomas Müller4 Noriko Miyake, Ryo Kogawa, Yoshie Komatsu, Naomichi Matsumoto, Andreas R Janecke, Shiro Ikegawa, Kazuyuki Sugahara
Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research, Honolulu, Hawaii   19 Nov 2014   
A numbers of genetic bone and skin disorders caused by defect in side chains of proteoglycans [Invited]
◯Shuji MIZUMOTO
16 Oct 2014   
A numbers of genetic bone and skin disorders caused by defect of glycosaminoglycans [Invited]
Shuji Mizmoto
7 Jun 2014   
Autosomal recessive form of brachyolmia caused by a mutation in PAPS synthase 2
◯Shuji Mizumoto, Aritoshi Iida, Pelin Özlem Simsek-Kiper, Touma Hoshino, Nursel Elcioglu, Eva Horemuzova, Stefan Geiberger, Gozde Yesil, Hülya Kayserili, Gülen Eda Utine, Koray Boduroglu, Shigehiko Watanabe, Hirofumi Ohashi, Yasemin Alanay, Gen Nishimura, Shiro Ikegawa, Kazuyuki Sugahara
30 Mar 2014   
Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage
◯Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, Kazuyuki Sugahara
The 85th Annual Meeting of the Japanese Biochemical Society   15 Dec 2012   
Receptor for Advanced Glycation End-products (RAGE) functions as a receptor for glycosaminoglycans involved in pulmonary metastasis
◯Shuji MIZUMOTO, Jun TAKAHASHI, Kazuyuki SUGAHARA
The 10th International Symposium for Future Drug Discovery and Medical Care, Sapporo   3 Oct 2012   
RAGE is a functional receptor for chondroitin sulfate involved in pulmonary metastasis of tumor cells
◯Shuji Mizumoto, Jun Takahashi, and Kazuyuki Sugahara
The 31st Japanese Carbohydrate Symposium   20 Sep 2012   
Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development
◯Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
26 Jul 2012   
Novel Larsen-like syndrome caused by a mutation in glucuronyltransferase-I
MIZUMOTO Shuji
29 Mar 2012   
Loss-of-function mutation of glucuronyltransferase-I causes Larsen-like syndrome
S. Baasanjav, L. Al-Gazali, T. Hashiguchi, ◯S. Mizumoto, K. Sugahara et al
7th International Conference on Proteoglycans, Sydney, Australia   18 Oct 2011   
Suppression of the metastasis of Lewis lung carcinoma cells by regulating the expression of chondroitin sulfate E structure
21 May 2011   

Research Grants & Projects

 
Crosstalk of chondroitin sulfate and filamin in hereditary bone dyaplasias
Project Year: Apr 2019 - Mar 2021    Investigator(s): Shuji Mizumoto
JSPS: Grant-in-Aid for Young Scientists(B)
Project Year: Apr 2011 - Mar 2013    Investigator(s): Shuji MIZUMOTO
Functinal analysis of chondroitin sulfate, dermatan sulfate, and heparan sulfate
Project Year: 2000