Kanaho Yasunori

J-GLOBAL         Last updated: May 14, 2019 at 02:51
Kanaho Yasunori
University of Tsukuba
University of Tsukuba
Job title
Executive Director
Research funding number

Research Areas



Graduate School, Division of Pharmaceutical Sciences, Kyoto Pharmaceutical University

Published Papers

Kinoshita-Kawada, Mariko; Hasegawa, Hiroshi; Hongu, Tsunaki; Yanagi, Shigeru; Kanaho, Yasunori; Masai, Ichiro; Mishima, Takayasu; Chen, Xiaoping; Tsuboi, Yoshio; Rao, Yi; Yuasa-Kawada, Junichi; Wu, Jane Y
Development (Cambridge, England)   146(3)    Feb 2019   [Refereed]
A switch in the response of commissural axons to the repellent Slit is crucial for ensuring that they cross the ventral midline only once. However, the underlying mechanisms remain to be elucidated. We have found that both endocytosis and recyclin...
Lin, Yueh-Chien; Chen, Chien-Chin; Chen, Wei-Min; Lu, Kuan-Ying; Shen, Tang-Long; Jou, Yeong-Chin; Shen, Cheng-Huang; Ohbayashi, Norihiko; Kanaho, Yasunori; Huang, Yuan-Li; Lee, Hsinyu
Biochimica et biophysica acta   1863(10) 1305-1315   Jul 2018   [Refereed]
Lysophosphatidic acid (LPA) is a bioactive lipid growth factor which is present in high levels in serum and platelets. LPA binds to its specific G-protein-coupled receptors, including LPA to LPA, thereby regulating various physiological functions,...
Ngo Thai Bich, Van; Hongu, Tsunaki; Miura, Yuki; Katagiri, Naohiro; Ohbayashi, Norihiko; Yamashita-Kanemaru, Yumi; Shibuya, Akira; Funakoshi, Yuji; Kanaho, Yasunori
Scientific reports   8(1) 6283   Apr 2018   [Refereed]
Two major phospholipase D (PLD) isozymes in mammals, PLD1 and PLD2, hydrolyze the membrane phospholipid phosphatidylcholine to choline and the lipid messenger phosphatidic acid. Although their roles in cancer cells have been well studied, their fu...
Kandori, Shuya; Kojima, Takahiro; Matsuoka, Taeko; Yoshino, Takayuki; Sugiyama, Aiko; Nakamura, Eijiro; Shimazui, Toru; Funakoshi, Yuji; Kanaho, Yasunori; Nishiyama, Hiroyuki
Cancer science   109(6) 1865-1875   Apr 2018   [Refereed]
A hallmark of clear cell renal cell carcinoma (ccRCC) is the presence of intracellular lipid droplets (LD) and it is assumed that phosphatidic acid (PA) produced by phospholipase D (PLD) plays some roles in the LD formation. However, little is kno...
Ganesan, Ramya;Henkels, Karen M.;Wrenshall, Lucile E.;Kanaho, Yasunori;Paolo, Gilbert Di;Frohman, Michael A.;Gomez‐Cambronero, Julian
Journal of Leukocyte Biology   103(5) 867-883   Apr 2018   [Refereed]
The uptake of cholesterol carried by low-density lipoprotein (LDL) is tightly controlled in the body. Macrophages are not well suited to counteract the cellular consequences of excess cholesterol leading to their transformation into "foam cells," ...

Books etc

Common Diseaseの病態生理と薬物療法
鈴木, 英雄;奈良坂俊明;原晃;金保安則;寺田弘 (Part:Contributor, 小腸・大腸)
Mar 2019   
Canser Sci
kandori, S;Kojima, T;Matsuoka, T;Yoshino, T;Sugiyama, A;Nakamura, E;Simazui, T;Funakoshi, Y;Kanaho, Y;Nishiyama, H (Part:Contributor, Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin)
Apr 2018   
大林, 典彦;金保, 安則 (Part:Contributor, 小胞輸送)
医学書院   Oct 2015   
金保,安則;本宮,綱記 (Part:Supervisor, 低分子量Gタンパク質Arf6の個体における多彩な生理機能)
Feb 2016   
金保,安則;秋山,雅博 (Part:Supervisor, 生化学・分子生物学 低分子量G蛋白質Arf6の髄鞘形成における役割)
Jan 2016   

Conference Activities & Talks

小倉由希乃;船越祐司;大林典彦;金保, 安則
第41回日本分子生物学会年会   29 Nov 2018   
Function of TBC1D24 in clathrin-independent endocytic cargo trafficking.
Nguyen, Nguyen Thi Kim;大林典彦;船越祐司;Kanaho, Yasunori
第91回日本生化学会大会   25 Sep 2018   
Function of TBC1D24 in clathrin-independent endocytic cargo trafficking
Nguyen, Nguyen Thi Kim;Funakoshi, Yuji;Kanaho, Yasunori
2017 The 16th Joint Mini-Symposium 2017 of National Taiwan University, Kyoto University and University of Tsukuba   24 Sep 2017   
Phospholipase D2 is a key molecule to suppress tumorigenesis through proliferation of CD8+ T lymphocytes
Van, Ngo Thai Bich;Hongu, Tsunaki;Funakoshi, Yuji;Kanah, Yasunori
2017 The 16th Joint Mini-Symposium 2017 of National Taiwan University, Kyoto University and University of Tsukuba   24 Sep 2017   
Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP2-producing enzyme PIP5K1A [Invited]
Funakoshi, Yuji;Tsai, Meng-Tsz;Katagiri, Naohiro;Ohbayashi, Norihiko;Iwasaki, Kenichi;Ohkohchi, Nobuhiro;Ding, Shih-Torng;Kanaho, Yasunori
2017 The 16th Joint Mini-Symposium 2017 of National Taiwan University, Kyoto University and University of Tsukuba   24 Sep 2017   


特願2010−050431 : Arf6遺伝子機能喪失動物及びその利用方法
特願2010-050431 : Arf6遺伝子機能喪失動物及びその利用方法
特願2010-063109 : GTP結合型ARF6タンパク質の測定方法及びその用途
特願2004-292123 : アレルギーマウス
金保, 安則