2008年1月1日
Kinesin-Based Transportation and Electrofusion of Lipid Vesicles
The 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2008)
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- 記述言語
- 英語
- 会議種別
- 口頭発表(一般)
A hybrid bio-electrical system for direct transportation and electrofusion of lipid vesicles is proposed; this system is the reconstruction of an intracellular transportation mechanism responsible for endocytosis. The transportation was achieved along immobilized microtubules without any liquid manipulation by using kinesin motility, a biomolecular motor. The fusion of lipid vesicles was accomplished by applying electric pulses on micro-fabricated electrodes inside a flow cell. Together with encapsulation of particles/reactants within lipid vesicles, these results give us hope to build a nano-scale reactor inspired by the cellular mechanism. © 2008 CBMS.