論文

査読有り 国際誌
2020年1月14日

Association of sarcopenia with phase angle and body mass index in kidney transplant recipients.

Scientific reports
  • Akihiro Kosoku
  • Junji Uchida
  • Shunji Nishide
  • Kazuya Kabei
  • Hisao Shimada
  • Tomoaki Iwai
  • Keiko Maeda
  • Yoshiko Hanayama
  • Takuma Ishihara
  • Toshihide Naganuma
  • Yoshiaki Takemoto
  • Tatsuya Nakatani
  • 全て表示

10
1
開始ページ
266
終了ページ
266
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41598-019-57195-z

Malnutrition is an important risk factor for the development of sarcopenia. Recently, phase angle (PhA) obtained from the bioelectrical impedance analysis is increasingly becoming known as a nutritional status marker and may be considered a good indicator to identify elderly patients at risk of sarcopenia. In this study, we investigated the prevalence of sarcopenia and the relationship between sarcopenia and PhA or body mass index (BMI) as nutritional factors, and evaluated the discrimination performance of these nutritional factors for sarcopenia in 210 kidney transplant recipients. The median age was 55 years and 11.1% had sarcopenia. This prevalence of sarcopenia was lower than previous reports in kidney transplant recipients, maybe because of the differences in sarcopenia definitions and population demographics such as age, sex, race, and comorbidities. Both PhA and BMI were negatively correlated with sarcopenia after adjusting for age, sex, dialysis vintage, time after transplant, presence of diabetes mellitus, hemoglobin, estimated glomerular filtration rate, and the other nutritional factor. The discrimination performance for PhA and BMI had enough power to detect sarcopenia. These results suggest that PhA and BMI can be used in clinical practice to predict sarcopenia in kidney transplant patients.

リンク情報
DOI
https://doi.org/10.1038/s41598-019-57195-z
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31937826
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959331
ID情報
  • DOI : 10.1038/s41598-019-57195-z
  • PubMed ID : 31937826
  • PubMed Central 記事ID : PMC6959331

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