2013年
Successful Treatment of a Patient with Multicentric Castleman's Disease who Presented with Thrombocytopenia, Ascites, Renal Failure and Myelofibrosis Using Tocilizumab, an Anti-Interleukin-6 Receptor Antibody
INTERNAL MEDICINE
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- 巻
- 52
- 号
- 13
- 開始ページ
- 1503
- 終了ページ
- 1507
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2169/internalmedicine.52.9482
- 出版者・発行元
- JAPAN SOC INTERNAL MEDICINE
We herein describe an unusual case of multicentric Castleman's disease accompanied by thrombocytopenia, ascites, renal failure and myelofibrosis in a Japanese woman. The patient was initially diagnosed as having myelodysplastic syndrome with myelofibrosis. The general condition of the patient deteriorated rapidly; however, treatment with tocilizumab, an anti-interleukin-6 receptor antibody, together with corticosteroids dramatically improved her symptoms. The clinical features of this case were similar to those of three cases previously reported by Takai et al. (Rinsho Ketsueki, 2010, 51:320-5), which were determined to be thrombocytopenia, anasarca, fever, reticulin myelofibrosis and organomegaly (TAFRO) syndrome, a possibly distinct clinical entity.
- リンク情報
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- DOI
- https://doi.org/10.2169/internalmedicine.52.9482
- CiNii Articles
- http://ci.nii.ac.jp/naid/130003365696
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/23812199
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000321862100010&DestApp=WOS_CPL
- ID情報
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- DOI : 10.2169/internalmedicine.52.9482
- ISSN : 0918-2918
- CiNii Articles ID : 130003365696
- PubMed ID : 23812199
- Web of Science ID : WOS:000321862100010