Nobue Kitanaka

Profile Information

Affiliation: Associate Professor, Department of Pharmacology, School of Medicine, Hyogo Medical University

Degree: 医学博士(兵庫医科大学)
薬学修士(大阪大学)

Researcher number: 30340954
ORCID ID: https://orcid.org/0000-0001-8951-7871
J-GLOBAL ID: 201901008569006526
researchmap Member ID: B000365413

External link: http://www.hyo-med.ac.jp

Research Interests

Research Areas

Research History

Apr, 2004 - Present

Hyogo College of Medicine
Jul, 2001 - Mar, 2004

Hyogo College of Medicine
Jul, 1999 - Jun, 2001

Hyogo College of Medicine
May, 2000 - Jun, 2000

Hyogo College of Medicine
Jul, 1997 - Jun, 1999

Guest Researcher, アメリカ合衆国国立薬物乱用研究所 (NIH/NIDA, Baltimore, MD)
Apr, 1996 - Jun, 1997

研究員, 医薬開発研究所, 日本イーライリリー株式会社

Education

Apr, 1994 - Mar, 1996

応用薬学専攻, 薬学研究科, 大阪大学大学院
Apr, 1990 - Mar, 1994

School of Pharmaceutical Sciences, Osaka University

Committee Memberships

2010 - Present

代議員, 公益社団法人日本薬理学会
2004 - Present

学術評議員, 公益社団法人日本薬理学会

Papers

Opioid receptor antagonists reduce motivated wheel running behavior in mice

35(2/3) 114-121, Mar, 2024 Peer-reviewedLead author
Role of Glycogen Synthase Kinase-3beta in Dependence and Abuse Liability of Alcohol

Masahiro Oka, Rui Yoshino, Nobue Kitanaka, F. Scott Hall, George R. Uhl, Junichi Kitanaka

Alcohol and Alcoholism, 59(2) agad086. doi: 10.1093/alcalc/agad086, Mar, 2024 Peer-reviewed
Therapeutic potential for KCC2-targeted neurological diseases

59 431-438, Nov, 2023 Peer-reviewedInvited
Kamishoyosan and Kamikihito protect against decreased KCC2 expression via neuroinflammation induced by the P. gingivalis lipopolysaccharide treatment in PC-12 cells and improve behavioral abnormalities in male mice

Kazuo Tomita, Yukiko Oohara, Kento Igarashi, Junichi Kitanaka, Nobue Kitanaka, Koh-ichi Tanaka, Mehryar, Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Mitsutaka Sugimura …

Heliyon, 9(12) e22784, Nov, 2023 Peer-reviewed
Glycogen synthase kinase-3 inhibitors block morphine-induced locomotor activation, Straub tail, and depression of rearing in mice via a possible central action

48(7) 2230-2240, Mar, 2023 Peer-reviewed
Are histamine H3 antagonists the definitive treatment for acute methamphetamine intoxication?

Kitanaka N, Hall F.S, Tanaka K, Tomita K, Igarashi K, Nishiyama N, Sato T, Uhl G.R, Kitanaka J

Current Drug Research Reviews, 14(3) 162-170, Oct, 2022 Peer-reviewedLead author
Neuroprotective effect of oxytocin on cognitive dysfunction, DNA damage, and intracellular chloride disturbance in young mice after cranial irradiation.

Igarashi K, Iwai H, Tanaka KI, Kuwahara Y, Kitanaka J, Kitanaka N, Kurimasa A, Tomita K, Sato T

Biochemical and biophysical research communications, 612 1-7, Apr, 2022 Peer-reviewed
Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice.

Nobue Kitanaka, F Scott Hall, Shotaro Kobori, Sota Kushihara, Hiroyuki Oyama, Yasuki Sasaoka, Megumi Takechi, Koh-Ichi Tanaka, Kazuo Tomita, Kento Igarashi …

Pharmacology, biochemistry, and behavior, 209C 173257-173257, Aug, 2021 Peer-reviewedLead author
In vivo evaluation of effects of histamine H3 receptor antagonists on methamphetamine-induced hyperlocomotion in mice.

Junichi Kitanaka, Nobue Kitanaka, F Scott Hall, Yukie Amatsu, Kotaku Hashimoto, Erina Hisatomi, Eri Kitao, Mari Mimura, Miyu Nakamura, Rena Ozawa …

Brain research, 1740 146873-146873, Aug 1, 2020 Peer-reviewed
Lithium Pharmacology and a Potential Role of Lithium on Methamphetamine Abuse and Dependence.

Kitanaka N, Hall FS, Uhl GR, Kitanaka J

Current drug research reviews, 11(2) 85-91, Jan, 2019 Peer-reviewed
CRR細胞における過酸化水素耐性機構の解析

富田和男, 桑原義和, 高裕子, 五十嵐健人, 長澤大成, 山西沙祐里, 大内裕也, 並河英紀, 田中康一, 北中純一 …

応用薬理, 94(5-6) 123-123, Jul, 2018
Tetrabenazine, a vesicular monoamine transporter-2 inhibitor, attenuates morphine-induced hyperlocomotion in mice through alteration of dopamine and 5-hydroxytryptamine turnover in the cerebral cortex.

Kitanaka N, Kitanaka J, Hall FS, Kandori T, Murakami A, Muratani K, Nakano T, Uhl GR, Takemura M

Pharmacology, biochemistry, and behavior, 172 9-16, Jul, 2018 Peer-reviewed
Psychotomimetic-like behavioral effects of memantine in the mouse

Nobue Kitanaka, Junichi Kitanaka, F. Scott Hall, Yoshiro Kubota, Yumi Mimura, Sayaka Ogura, Yukiya Okada, George R. Uhl, Motohiko Takemura

Biomedicine and Pharmacotherapy, 100 116-123, Apr 1, 2018 Peer-reviewed
17α-エストラジオールは繰り返しストレス下に置かれたOVXマウスの海馬においてGPR30を介したSPAK-KCC2活動を調節する(17α-estradiol regulates SPAK-KCC2 activity via GPR30 in the hippocampus of repeated stressed OVX mice)

Tsukahara Takao, Furukawa Minami, Tomita Kazuo, Tanaka Koh-ichi, Kitanaka Nobue, Kitanaka Junichi, Takemura Motohiko, Nishiyama Nobuyoshi, Miyawaki Shouichi, Sato Tomoaki

Journal of Pharmacological Sciences, 133(3Suppl.) S93-S93, Mar, 2017
新生児母子分離はKCC2ダウンレギュレーションを介して興奮から抑制へのGABAスイッチ時期を遅延させる(Neonatal maternal separation delays the timing of excitatory-to-inhibitory GABA switch via down-regulation of KCC2)

Furukawa Minami, Tsukahara Takao, Tomita Kazuo, Tanaka Koh-ichi, Kitanaka Nobue, Kitanaka Junichi, Takemura Motohiko, Nishiyama Nobuyoshi, Miyawaki Shouichi, Sato Tomoaki

Journal of Pharmacological Sciences, 133(3Suppl.) S223-S223, Mar, 2017
How the histamine N-methyltransferase inhibitor metoprine alleviates methamphetamine reward.

Kitanaka N, Kitanaka J, Hall FS, Okumura S, Sakamoto T, Uhl GR, Takemura M

J. Addict. Med. Ther. Sci., 3(2) 16-23, 2017 Peer-reviewed
The absence of the SOD1 gene causes abnormal monoaminergic neurotransmission and motivational impairment-like behavior in mice

Daisaku Yoshihara, Noriko Fujiwara, Nobue Kitanaka, Junichi Kitanaka, Haruhiko Sakiyama, Hironobu Eguchi, Motohiko Takemura, Keiichiro Suzuki

FREE RADICAL RESEARCH, 50(11) 1245-1256, Nov, 2016 Peer-reviewed
Brain histamine N-methyltransferase as a possible target of treatment for methamphetamine overdose

Junichi Kitanaka, Nobue Kitanaka, F. Scott Hall, George R. Uhl, Motohiko Takemura

Drug Target Insights, 10 1-7, Mar 2, 2016 Peer-reviewed
Memory impairment and reduced exploratory behavior in mice after administration of systemic morphine

Junichi Kitanaka, Nobue Kitanaka, F. Scott Hall, Mei Fujii, Akiko Goto, Yusuke Kanda, Akira Koizumi, Hirotoshi Kuroiwa, Satoko Mibayashi, Yumi Muranishi …

Journal of Experimental Neuroscience, 9(1) 27-35, 2015 Peer-reviewed
Pretreatment or posttreatment with aripiprazole attenuates methamphetamine-induced stereotyped behavior in mice

Nobue Kitanaka, Junichi Kitanaka, F.Scott Hall, Masaru Kayama, Hironobu Sugimori, George R. Uhl, Motohiko Takemura

Journal of Experimental Neuroscience, 2015(Suppl 1) 11-10, 2015 Peer-reviewed

Misc.

SOD1欠損マウスにおける脳内モノアミン代謝の変化と行動異常

吉原大作, 藤原範子, 北中順惠, 北中純一, 江口裕伸, 崎山晴彦, 竹村基彦, 鈴木敬一郎

日本酸化ストレス学会学術集会プログラム・抄録集, 75th (CD-ROM), 2022
Analysis of oxidative stress response in clinically relevant radioresistant cells.

Tomita K, Kuwahara Y, Takashi Y, Yamanishi S, Nabika H, Tanaka K, Kitanaka J, Kitanaka N, Takemura M, Nishiyama N …

18th World Congress of Basic and Clinical Pharmacology, Jul, 2018 Peer-reviewed
覚せい剤がもたらす脳の変化とヒスタミン神経系

北中純一, 北中順惠, 竹村基彦

脳２１, 18(2) 83-88, 2015 Invited
Assesment of cell death induced by oxidative stress in cultured astrocytes

Koh-ichi Tanaka, Nobue Kitanaka, Junichi Kitanaka, Junya Hanatani, Shyohko Asano, Erika Toumoto, Tomoaki Sato, Takashige Nishikawa, Motohiko Takemura, Akemichi Baba …

JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 147P-147P, 2014
Exogenous agmatine inhibits methamphetamine-induced stereotypy and hyperlocomotion in mice

Junichi Kitanaka, Nobue Kitanaka, F. Scott Hal, George. R. Uhl, Koh-ichi Tanaka, Nobuyoshi Nishiyama, Tomohiro Tatsuta, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 218P-218P, 2014
A single administration of morphine impairs Morris water maze task in mice

Nobue Kitanaka, Junichi Kitanaka, Akira Koizumi, Minako Sumikawa, Soichiro Otaki, Hirotoshi Kuroiwa, Mei Fujii, Koh-ichi Tanaka, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 124 218P-218P, 2014
Acute morphine exposure impairs spatial memory in mice

Nobue Kitanaka, Junichi Kitanaka, Akiko Goto, Satoko Mibayashi, Yusuke Kanda, Yumi Muranishi, Koh-ichi Tanaka, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 121 144P-144P, 2013
Expression of CNT in astrocytes and mechanism of thymidine incorporation into acid insoluble fraction on oxidative stress DNA injury

Koh-ichi Tanaka, Nobue Kitanaka, Junichi Kitanaka, Shyohn Yokoyama, Junya Hanatani, Minse Pak, Teruhisa Miyake, Haruna Oh-i, Yuriko Kishi, Tomoaki Sato …

JOURNAL OF PHARMACOLOGICAL SCIENCES, 121 138P-138P, 2013
Opioid receptor antagonists attenuate methamphetamine-induced stereotypical behavior in mice

Nobue Kitanaka, Junichi Kitanaka, Tatsuo Sawai, Yuko Fukushima, Koh-ichi Tanaka, Tomohiro Tatsuta, Yoshio Morita, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 121 183P-183P, 2013
Mechanism of thymidine incorporation into astrocytic acid insoluble fraction via SLC28 and SLC29 on oxidative stress DNA injury

K. -I. Tanaka, N. Kitanaka, J. Kitanaka, S. Yokoyama, T. Miyake, M. Park, J. Hanatani, H. Ohi, Y. Kishi, T. Sato …

JOURNAL OF NEUROCHEMISTRY, 123 65-65, Oct, 2012
Hypothalamic histamine levels are negatively correlated with expression frequency of methamphetamine-induced stereotypical biting in mice

J. Kitanaka, N. Kitanaka, F. C. Hall, G. R. Uhl, K. -I. Tanaka, N. Nishiyama, M. Takemura

JOURNAL OF NEUROCHEMISTRY, 123 79-79, Oct, 2012
Extinction of methamphetamine reward is facilitated by experience of running wheel in mice

Nobue Kitanaka, Junichi Kitanaka, Kaname Watabe, Hitoshi Kubo, Hitoshi Takahashi, Koh-ichi Tanaka, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 237P-237P, 2012
Mechanism of thymidine incorporation into acid insoluble fraction on oxidative stress DNA injury

Koh-ichi Tanaka, Nobue Kitanaka, Junichi Kitanaka, Shyohn Yokoyama, Yuriko Kishi, Tomoaki Sato, Takashige Nishikawa, Motohiko Takemura, Akemichi Baba, Nobuyoshi Nishiyama

JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 227P-227P, 2012
Isoliquiritigenin, a licorice flavonoid, blocks methamphetamine-induced locomotor hyperactivity in mice

Junichi Kitanaka, Nobue Kitanaka, Hiroki Minami, Masayuki Okamoto, Koh-ichi Tanaka, Tomohiro Tatsuta, Yoshio Morita, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 118 237P-237P, 2012
Effect of isoliquiritigenin, a licorice flavonoid, on methamphetamine-induced rewarding property, hyperactivity and stereotypy in mice

Junichi Kitanaka, Nobue Kitanaka, Masayuki Okamoto, Hiroki Minami, Koh-ichi Tanaka, Tomohiro Tatsuta, Yoshio Morita, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 146P-146P, 2011
Alterations in hypothalamic histamine levels are associated with expression frequency of methamphetamine-induced stereotypical biting in mice

Junichi Kitanaka, Nobue Kitanaka, F. Scott Hall, George. R. Uhl, Koh-ichi Tanaka, Tomohiro Tatsuta, Yoshio Morita, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 250P-250P, 2011
Thymidine incorporation via nucleoside transporters on oxidative stress DNA injury

Koh-ichi Tanaka, Nobue Kitanaka, Junichi Kitanaka, Tomoaki Sato, Takashige Nishikawa, Motohiko Takemura, Akemichi Baba, Nobuyoshi Nishiyama

JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 134P-134P, 2011
Effect of experience of running wheel on methamphetamine-induced conditioned place preference in mice

Nobue Kitanaka, Junichi Kitanaka, Kaname Watabe, Koh-ichi Tanaka, Tomohiro Tatsuta, Yoshio Morita, Nobuyoshi Nishiyama, Motohiko Takemura

JOURNAL OF PHARMACOLOGICAL SCIENCES, 115 146P-146P, 2011
The aim of thymidine incorporation via nucleoside transporters on oxidative stress

Koh-ichi Tanaka, Nobue Kitanaka, Junichi Kitanaka, Yuriko Kishi, Shyohn Yokoyama, Tomoaki Sato, Takashige Nishikawa, Motohiko Takemura, Akemichi Baba, Nobuyoshi Nishiyama

NEUROSCIENCE RESEARCH, 71 E222-E222, 2011
Acute administration of methamphetamine decreases running wheel activity in mice

Nobue Kitanaka, Junichi Kitanaka, Kaname Watabe, F. Scott Hall, George R. Uhl, Koh-ichi Tanaka, Nobuyoshi Nishiyama, Motohiko Takemura

NEUROSCIENCE RESEARCH, 71 E396-E396, 2011

Books and Other Publications

Chapter 7. Glycogen synthase kinase-3β and methamphetamine abuse liability (In: Advances in Health and Disease. Volume 55, Lowell T. Duncan (Editor))

Junichi Kitanaka, Nobue Kitanaka, F. Scott Hall, Logan E. Kountz, Takuma Hashimoto, Kai Hirabayashi, Utau Horie, Kenta Iwasaki, Yumi Kawasaki, Minami Kimura, Takashi Sakamoto, Junya Yashiro, Kazuo Tomita, Kento Igarashi, Koh-ichi Tanaka, George R. Uhl, Tomoaki Sato, Nobuyoshi Nishiyama (Role: Joint author)

Nova Science Publishers, Inc., New York, Aug, 2022 (ISBN: 9781685079987)
Anhedonia: A comprehensive handbook Volumes I & II

J. Kitanaka, N. Kitanaka, F.S. Hall, G.R. Uhl, M. Takemura (Role: Contributor)

2014
Methamphetamines: Abuse, Health Effects and Treatment Options (Ornoy, J., He, X., eds.)

Kitanaka N, Kitanaka J, Minami H, Okamoto H, Tatsuta T, Morita Y, Tanaka K, Nishiyama N, Takemura M (Role: Joint author, Chapter 5; Isoliquiritigenin, a licorice flavonoid, inhibits methamphetamine-induced hyperlocomotion but not stereotypy or conditioned place preference in mice.)

Nova Science Publishers, Inc., New York, pp. 131-151, 2012
Handbook of Neuropsychiatry Research (Davies, RS. ed.)

J. Kitanaka, N. Kitanaka, M. Takemura (Role: Joint author, Chapter 4; Sequential expression of impaired psychomotor and sensorimotor activities in rodents during amphetamine withdrawal.)

Nova Science Publishers, Inc., New York, pp. 97-112, 2010
Advances in Psychology Research Volume 60

J. Kitanaka, N. Kitanaka, T. Tatsuta, Y. Morita, H. Kinoshita, M. Takemura (Role: Joint author, Chapter 7: Regulating the expression patterns of bizarre behavior: a therapeutic option for amphetamine-type drug-induced stereotypy?)

Nova Science Publishers, Inc., New York; pp. 143-154, 2009

Presentations

241

幻覚剤DOIによるマウス行動異常・精神変調・モノアミン代謝回転について

北中純一, 湯瀬祥, 濱名貴大, 服巻里佳, 松田健太郎, 仲井聖典, 上田紫暉, 山本ひとみ, 北中順惠

令和5年度厚生労働科学研究費補助金（医薬品・医療機器等レギュラトリーサイエンス政策研究事業）＜班会議＞, Feb 16, 2024, 湘南医療大学薬学部・厚生労働省
ホスファチジルイノシトール3-キナーゼ阻害薬Wortmanninは、覚せい剤誘導繰り返し嗅ぎ行動および噛み行動を抑制し、その結果常同行動の発現全体を緩和する

濱名貴大, 北中順惠, 仲井聖典, 松田健太郎, 湯瀬祥, 富田和男, 五十嵐健人, 佐藤友昭, 北中純一

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 16, 2023, 日本薬理学会
幻覚剤2,5-dimethoxy-4-iodoamphetamineによって引き起こされる行動異常の特徴について

湯瀬祥, 北中順惠, 濱名貴大, 松田健太郎, 仲井聖典, 富田和男, 五十嵐健人, 佐藤友昭, 西山信好, 北中純一

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 16, 2023, 日本薬理学会
GSK-3阻害薬LY2090314前処置による覚せい剤誘導過運動・常同行動への効果

松田健太郎, 北中順惠, 濱名貴大, 仲井聖典, 湯瀬祥, 富田和男, 五十嵐健人, 佐藤友昭, 北中純一

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 16, 2023, 日本薬理学会
GSK-３阻害薬CHIR-99021前処置はモルヒネによるStraubの挙尾反応と退薬症状を抑制する

仲井聖典, 北中順惠, 濱名貴大, 松田健太郎, 湯瀬祥, 藤井舞, 津嶋祐一郎, 富田和男, 五十嵐健人, 佐藤友昭, 西山信好, 北中純一

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 16, 2023, 日本薬理学会
オピオイド受容体拮抗薬ナロキソン単回投与のマウス動機付け行動および脳モノアミン代謝回転への影響

北中順惠, 新井香奈代, 竹原薫生子, 富田和男, 五十嵐健人, 濱名貴大, 松田健太郎, 仲井聖典, 湯瀬祥, 佐藤友昭, 北中純一

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 16, 2023, 日本薬理学会
幻覚剤2,5-dimethoxy-4-idoamphetamineは短期空間記憶や気分の障害を引き起こす

北中純一, 北中順惠, 湯瀬祥, 濱名貴大, 松田健太郎, 仲井聖典, 富田和男, 五十嵐健人, 佐藤友昭, 西山信好

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 16, 2023, 日本薬理学会
放射線抵抗性がん細胞が抵抗性を失うと低下したFe2+量が親株レベルに戻る

富田和男, 桑原義和, Mehryar Habibi Roudkenar, 五十嵐健人, 田中康一, 北中純一, 北中順惠, 栗政明弘, 西山信好, 佐藤友昭

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 15, 2023, 日本薬理学会
隔離飼育されたddYマウスの攻撃的な咬合行動に対するジアゼパムの影響は雄と雌で異なる

五十嵐健人, 口岩聡, 口岩俊子, 富田和男, 田中康一, 北中純一, 北中順惠, 西山信好, 佐藤友昭

第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会, Dec 14, 2023, 日本薬理学会
Effect of opioid receptor antagonists on motivated behavior and monoamine turnover in mice

Nov 28, 2023
歯周病菌由来LPSによる神経機能障害に対する加味逍遙散と加味帰脾湯の効果

富田和男, 五十嵐健人, 北中純一, 北中順惠, 田中康一, 佐藤友昭

第40回和漢医薬学会学術大会, Aug 27, 2023, 和漢医薬学会
Effects of opioid receptor antagonists on motivative behavior and brain monoamine turnover in mice

Jul 6, 2023
μオピオイド受容体選択的拮抗薬単独与薬によるマウス動機付け行動への影響

北中純一, 北中順惠, 富田和男, 五十嵐健人, 新井香奈代, 竹原薫生子, 仲井聖典, 濱名貴大, 松田健太郎, 湯瀬祥, 佐藤友昭

第16回日本緩和医療薬学会, May 27, 2023, 日本緩和医療薬学会
DOI等試験薬物による特異的行動発現パターンのRating評価～用量・投与経路による比較

北中純一, 北中順惠, 仲井聖典, 濱名貴大, 松田健太郎, 湯瀬祥, 西山信好

令和4年度厚生労働科学研究費補助金（医薬品・医療機器等レギュラトリーサイエンス政策研究事業）＜班会議＞研究課題名：指定薬物の指定に係る試験法の評価検証に資する研究（22KC1005）, Feb 17, 2023, 湘南医療大学薬学部・厚生労働省
Expression and function of equilibrative nucleoside transporters in cultured astrocytes

Dec 3, 2022
Oxytocin administration to head gamma-irradiated mice results in increased KCC2 mRNA expression through decreased phosphorylated CREB

Dec 3, 2022
RAGE, which is the receptor for advanced glycation end-products, is involved in the regulation of KCC2 expression by the Porphyromonas gingivalis LPS treatment in PC-12 cells

Dec 1, 2022
Pretreatment with CHIR-99021, a GSK-3beta inhibitor, partially attenuates methamphetamine-induced stereotyped behavior in mice

Nov 30, 2022
Effect of -opioid receptor antagonist on spontaneous behavior in mice

Nov 30, 2022
ヒト歯根膜由来繊維芽細胞(HPLF)は歯周病菌由来LPS処理により鉄動態が変化しミトコンドリア機能が障害を受けフェロトーシスが誘導される

古川紗圭, 富田和男, 五十嵐健人, 田中康一, 北中純一, 北中順惠, 西山信好, 髙裕子, 西谷佳浩, 野口和行, 佐藤友昭

第75回日本薬理学会西南部会, Oct 1, 2022, 日本薬理学会

Teaching Experience

Aug, 2022 - Present

臨床薬理学 (兵庫医科大学臨床教育統括センター看護師特定行為研修（科目責任者）)
Apr, 2022 - Present

化学と生命 (兵庫医科大学看護学部・リハビリテーション学部)
2008 - Present

基礎系講座配属
基礎医学統合TBL (兵庫医科大学)
研究技術講習会 (兵庫医科大学大学院, 実施責任者)
薬理学 (兵庫医科大学医学部)
臨床薬理学 (兵庫医科大学医療人育成センター認定看護師教育課程（手術看護分野）, 科目責任者)
薬理学 (兵庫医科大学看護学部, 科目責任者)
薬理学実習 (兵庫医科大学、実施責任者)

Professional Memberships

Research Projects

ヒスタミン神経活性調節と薬物依存治療

日本学術振興会科学研究費, 基盤研究（C), 日本学術振興会, Apr, 2021 - Mar, 2024

北中純一, 北中順惠, 木村信也, 田中康一, 西山信好
依存性薬物の嗜好性発現と確立に寄与する細胞内情報伝達系の解明

科学技術人材育成費補助事業（令和３年度）ダイバーシティ研究環境実現イニシアティブ研究助成費助成キャリア支援研究助成（公的研究費）, Apr, 2021 - Mar, 2022

北中順惠
Morphineによる中枢興奮作用に関与する細胞内情報伝達経路の解明

科学技術人材育成費補助事業（令和２年度）ダイバーシティ研究環境実現イニシアティブ研究助成費助成キャリア支援研究助成（公的研究費）, Dec, 2020 - Mar, 2021

北中順惠
薬物依存脆弱性の個体差と覚せい剤治療効果との相関に関する研究

教員研究費助成金, 兵庫医科大学, Apr, 2019 - Mar, 2021

北中順惠
脳ヒスタミン不活性化経路と薬物依存治療

科学研究費補助金, 日本学術振興会, Apr, 2015 - Mar, 2018

北中純一
中枢神経系活性調節がもたらす覚せい剤誘発精神運動症状の変化に関する研究

教員研究費助成金, 兵庫医科大学, Apr, 2015 - Mar, 2017

北中順惠
覚せい剤メタンフェタミン依存形成に対する生体内物質アグマチンの作用

教員研究費助成金, 兵庫医科大学, Apr, 2013 - Mar, 2015

北中順惠
覚せい剤メタンフェタミンによる依存状態に対する豊かな環境の影響

教員研究費助成金, 兵庫医科大学, Apr, 2011 - Mar, 2013

北中順惠
Effect of running wheel on methamphetamine abuse in mice : a possible pharmacotherapy for drug abuse by environmental enrichment

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2009 - Mar, 2011

KITANAKA Nobue
メタンフェタミンの行動逆耐性誘発効果および報酬効果に対する抑制薬の探索

教員研究費助成金, 兵庫医科大学, Apr, 2005 - Mar, 2007

北中順惠
覚せい剤メタンフェタミンの依存形成にいたる過程の分子機構

教員研究費助成金, 兵庫医科大学, Apr, 2003 - Mar, 2005

北中順惠

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