Updated date: 2022/09/23

Construction and development of a comprehensive genome data infrastructure for pediatric cancer that contributes to the promotion of cancer genome medicine.

Created : 2022/09/23

共同研究・競争的資金等の研究課題の業績

がんゲノム医療の推進に資する小児がんの包括的ゲノムデータ基盤の構築と展開

日本医療研究開発機構

List of results of the research project

Narrowing down

Papers

Identification of RCC1-LCK as a novel fusion gene in pediatric erythroid sarcoma.

Satoru Oya, Shinya Osone, Masanori Yoshida, Sota Nishimoto, Yoshihiro Taura, Hideki Yoshida, Mitsuru Miyachi, Tohru Inaba, Eiichi Konishi, Motohiro Kato …

Pediatric blood & cancer, 69(9) e29848, Sep, 2022
Low NUDT15 expression levels due to biallelic NUDT15 variants and 6-mercaptopurine intolerance.

Masanori Yoshida, Scott A Brown, Takaya Moriyama, Rina Nishii, Shin-Ichi Tsujimoto, Yuji Yamada, Kaoru Yoshida, Ryota Shirai, Tomoo Osumi, Tomoyuki Utano …

British journal of haematology, 199(2) 270-276, Jul 29, 2022
A Case of Gorlin-Goltz Syndrome Without the Characteristic Physical Features That Was Diagnosed After the Development of a Fifth Cancer.

Daisuke Katayama, Akiko Inoue, Rishu Kayatani, Keisuke Urabe, Ryo Suzuki, Kimitaka Takitani, Masanori Yoshida, Motohiro Kato, Akira Ashida

Journal of pediatric hematology/oncology, 44(4) e869-e871, May 1, 2022
NUDT15 variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia

Masanori Yoshida, Kazuhiko Nakabayashi, Wentao Yang, Aiko Sato-Otsubo, Shin-ichi Tsujimoto, Hiroko Ogata-Kawata, Tomoko Kawai, Keisuke Ishiwata, Mika Sakamoto, Kohji Okamura …

Blood Advances, 5(23) 5420-5428, Dec 14, 2021
A case of primary CNS embryonal rhabdomyosarcoma with PAX3-NCOA2 fusion and systematic meta-review.

Ryuma Tanaka, Kyohei Inoue, Yuji Yamada, Masanori Yoshida, Haruko Shima, Jumpei Ito, Hajime Okita, Tomoru Miwa, Motohiro Kato, Hiroyuki Shimada

Journal of neuro-oncology, 154(2) 247-256, Sep, 2021
Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiopurine Intolerance During the Treatment of Acute Lymphoblastic Leukemia.

Ko Kudo, Tomohiko Sato, Yuka Takahashi, Kentaro Yuzawa, Akie Kobayashi, Takuya Kamio, Shinya Sasaki, Jun Shimada, Katsuki Otani, Shinichi Tusjimoto …

Journal of pediatric hematology/oncology, 43(8) e1173-e1176, Mar 31, 2021