論文

査読有り 国際誌
2020年1月

Isolation of an archaeon at the prokaryote-eukaryote interface.

Nature
  • Hiroyuki Imachi
  • ,
  • Masaru K Nobu
  • ,
  • Nozomi Nakahara
  • ,
  • Yuki Morono
  • ,
  • Miyuki Ogawara
  • ,
  • Yoshihiro Takaki
  • ,
  • Yoshinori Takano
  • ,
  • Katsuyuki Uematsu
  • ,
  • Tetsuro Ikuta
  • ,
  • Motoo Ito
  • ,
  • Yohei Matsui
  • ,
  • Masayuki Miyazaki
  • ,
  • Kazuyoshi Murata
  • ,
  • Yumi Saito
  • ,
  • Sanae Sakai
  • ,
  • Chihong Song
  • ,
  • Eiji Tasumi
  • ,
  • Yuko Yamanaka
  • ,
  • Takashi Yamaguchi
  • ,
  • Yoichi Kamagata
  • ,
  • Hideyuki Tamaki
  • ,
  • Ken Takai

577
7791
開始ページ
519
終了ページ
525
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41586-019-1916-6

The origin of eukaryotes remains unclear1-4. Current data suggest that eukaryotes may have emerged from an archaeal lineage known as 'Asgard' archaea5,6. Despite the eukaryote-like genomic features that are found in these archaea, the evolutionary transition from archaea to eukaryotes remains unclear, owing to the lack of cultured representatives and corresponding physiological insights. Here we report the decade-long isolation of an Asgard archaeon related to Lokiarchaeota from deep marine sediment. The archaeon-'Candidatus Prometheoarchaeum syntrophicum' strain MK-D1-is an anaerobic, extremely slow-growing, small coccus (around 550 nm in diameter) that degrades amino acids through syntrophy. Although eukaryote-like intracellular complexes have been proposed for Asgard archaea6, the isolate has no visible organelle-like structure. Instead, Ca. P. syntrophicum is morphologically complex and has unique protrusions that are long and often branching. On the basis of the available data obtained from cultivation and genomics, and reasoned interpretations of the existing literature, we propose a hypothetical model for eukaryogenesis, termed the entangle-engulf-endogenize (also known as E3) model.

リンク情報
DOI
https://doi.org/10.1038/s41586-019-1916-6
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31942073
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015854
ID情報
  • DOI : 10.1038/s41586-019-1916-6
  • PubMed ID : 31942073
  • PubMed Central 記事ID : PMC7015854

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