論文

査読有り
2020年

Accelerated Effect of MatriStem on Dentin Regeneration in Rats

Journal of Oral Tissue Engineering
  • ONJI Keiko
  • ,
  • SAITO Takashi
  • ,
  • KOIKE Toshiyuki
  • ,
  • POLAN Mohammad Ali Akbor
  • ,
  • HASAN Md Riasat
  • ,
  • ALTERHISHIG Bayarchimeg
  • ,
  • RAO Yaxin
  • ,
  • QIU Youjin
  • ,
  • MATSUDA Yasuhiro
  • ,
  • BESSHO Kazuhisa

18
1
開始ページ
23
終了ページ
28
記述言語
英語
掲載種別
DOI
10.11223/jarde.18.23
出版者・発行元
日本再生歯科医学会

<p>The purpose of the present study was to investigate the effect of MatriStem derived from porcine bladder on reparative dentin formation and pulp inflammation in vivo compared with mineral trioxide aggregate and calcium hydroxide that have been used for vital pulp therapy. Exposed pulp tissue in the maxilla first molar of 8-week-old Wistar rats was covered with those materials. The rats were sacrificed 4 weeks after the operation. We performed histological examination of hematoxylin and eosin-stained sections of teeth that underwent direct pulp capping, followed by morphometric analysis of formed reparative dentin and evaluation of pulp inflammation. At 4 weeks, MatriStem formed highly compact, intensively reparative dentin with dentinal tubules. MatriStem induced less pulp inflammation than calcium hydroxide. This study suggests that MatriStem is a biocompatible, biodegradable, and bioactive material with growth factors such as bone morphogenetic proteins for dentin regeneration.</p>

リンク情報
DOI
https://doi.org/10.11223/jarde.18.23
CiNii Articles
http://ci.nii.ac.jp/naid/130007927027

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