松本博樹 (Hiroki Matsumoto) - マイポータル

基本情報

所属: 東京大学アイソトープ総合センター特任教授

研究者番号: 00592916
ORCID iD: https://orcid.org/0000-0003-4044-0281
J-GLOBAL ID: 202401008898092093
researchmap会員ID: R000079687

論文

Local therapy with hypoxia-targeting radiopharmaceutical [64Cu]Cu-ATSM in high-grade glioma patient-derived xenograft models

Yukie Yoshii, Fukiko Hihara, Hiroki Matsumoto, Chika Igarashi, Tomoko Tachibana, Mitsuhiro Shinada, Makoto Ohtake, Hisashi Suzuki, Ming-Rong Zhang, Akito Oshima …

Radiotherapy and Oncology 2026年1月
Efficacy of radioactive hypoxia-targeting therapeutic agent 64Cu-ATSM on recurrent malignant glioma: a study protocol for a phase-III, investigator-sponsored, randomized controlled trial

Yayoi Ando, Shunsuke Yanagisawa, Makoto Ohno, Hiroaki Kurihara, Kimiteru Ito, Masahiko Ichimura, Kenta Anjo, Masako Inaba, Yukari Nagasaka, Ryo Sadachi …

Japanese Journal of Clinical Oncology 2025年4月26日
放射性治療薬[⁶⁴Cu]Cu-ATSM投与後の治療病室における空気中の放射能濃度

公輝伊藤, 宏明栗原, 博樹松本, 知子立花, 幸恵吉井, 善孝成田, 眞細野

核医学 2025年
⁶⁴Cu²⁺Complexes of Tripodal Amine Ligands’ In Vivo Tumor and Liver Uptakes and Intracellular Cu Distribution in the Extrahepatic Bile Duct Carcinoma Cell Line TFK-1: A Basic Comparative Study

Mitsuhiro Shinada, Masashi Takahashi, Chika Igarashi, Hiroki Matsumoto, Fukiko Hihara, Tomoko Tachibana, Masakazu Oikawa, Hisashi Suzuki, Ming-Rong Zhang, Tatsuya Higashi …

Pharmaceuticals 2024年6月
Trace Metal Impurities Effects on the Formation of [⁶⁴Cu]Cu-diacetyl-bis(N⁴-methylthiosemicarbazone) ([⁶⁴Cu]Cu-ATSM)

Shinada, M., Suzuki, H., Hanyu, M., Igarashi, C., Matsumoto, H., Takahashi, M., Hihara, F., Tachibana, T., Sogawa, C., Zhang, M.-R. …

Pharmaceuticals 17(1) 2024年
Process to Remove the Size Variants Contained in the Antibody–Chelator Complex PCTA-NCAB001 for Radiolabeling with Copper-64

Yoshii, Y., Matsumoto, H., Igarashi, C., Tachibana, T., Hihara, F., Shinada, M., Waki, A., Yoshida, S., Naito, K., Ito, K. …

Pharmaceuticals 16(10) 2023年
An In Vivo Dual-Observation Method to Monitor Tumor Mass and Tumor-Surface Blood Vessels for Developing Anti-Angiogenesis Agents against Submillimeter Tumors

Tachibana, T., Oyama, T.G., Yoshii, Y., Hihara, F., Igarashi, C., Shinada, M., Matsumoto, H., Higashi, T., Kishimoto, T., Taguchi, M.

International Journal of Molecular Sciences 24(24) 2023年
Identification and quantitative structure–activity relationship assessment of trace chemical impurities contained in the therapeutic formulation of [⁶⁴Cu]Cu-ATSM

Igarashi, C., Matsumoto, H., Takahashi, M., Hihara, F., Tachibana, T., Zhang, M.-R., Kurihara, H., Higashi, T., Yoshii, Y.

Nuclear Medicine and Biology 108-109 2022年
Preclinical Safety Evaluation of Intraperitoneally Administered Cu-Conjugated Anti-EGFR Antibody NCAB001 for the Early Diagnosis of Pancreatic Cancer Using PET

Matsumoto, H., Igarashi, C., Tachibana, T., Hihara, F., Shinada, M., Waki, A., Yoshida, S., Naito, K., Kurihara, H., Ueno, M. …

Pharmaceutics 14(9) 2022年
Characterization and Stabilization of a New 64Cu-Labeled Anti-EGFR Antibody NCAB001 for the Early Detection of Pancreatic Cancer with Positron Emission Tomography

Matsumoto, H., Igarashi, C., Tachibana, T., Hihara, F., Waki, A., Zhang, M.-R., Yoshida, S., Naito, K., Kurihara, H., Ueno, M. …

Pharmaceutics 14(1) 2022年
In Vitro Tumor Cell-Binding Assay to Select High-Binding Antibody and Predict Therapy Response for Personalized⁶⁴Cu-Intraperitoneal Radioimmunotherapy against Peritoneal Dissemination of Pancreatic Cancer: A Feasibility Study

Hihara, F., Matsumoto, H., Yoshimoto, M., Masuko, T., Endo, Y., Igarashi, C., Tachibana, T., Shinada, M., Zhang, M.-R., Kurosawa, G. …

International Journal of Molecular Sciences 23(10) 2022年
Efficacy of vorinostat-sensitized intraperitoneal radioimmunotherapy with 64 Cu-labeled cetuximab against peritoneal dissemination of gastric cancer in a mouse model

Tachibana, T., Yoshii, Y., Matsumoto, H., Zhang, M.-R., Nagatsu, K., Hihara, F., Igarashi, C., Sugyo, A., Tsuji, A.B., Higashi, T.

Journal of Cancer Research and Therapeutics 18(4) 2022年
Evaluation of aminopolycarboxylate chelators for whole-body clearance of free²²⁵ac: A feasibility study to reduce unexpected radiation exposure during targeted alpha therapy

Yoshimoto, M., Yoshii, Y., Matsumoto, H., Shinada, M., Takahashi, M., Igarashi, C., Hihara, F., Tachibana, T., Doi, A., Higashi, T. …

Pharmaceutics 13(10) 2021年
Usefulness of PET-guided surgery with ⁶⁴Cu-labeled cetuximab for resection of intrapancreatic residual tumors in a xenograft mouse model of resectable pancreatic cancer

Igarashi, C., Yoshii, Y., Tashima, H., Iwao, Y., Sakurai, K., Hihara, F., Tachibana, T., Yoshida, E., Wakizaka, H., Akamatsu, G. …

Nuclear Medicine Communications 2021年
Evaluation of⁶⁴cu-labeled new anti-egfr antibody ncab001 with intraperitoneal injection for early pet diagnosis of pancreatic cancer in orthotopic tumor-xenografted mice and nonhuman primates

Matsumoto, H., Watabe, T., Igarashi, C., Tachibana, T., Hihara, F., Waki, A., Zhang, M.-R., Tashima, H., Yamaya, T., Ooe, K. …

Pharmaceuticals 14(10) 2021年
Immuno-OpenPET: a novel approach for early diagnosis and image-guided surgery for small resectable pancreatic cancer

Yukie Yoshii, Hideaki Tashima, Yuma Iwao, Eiji Yoshida, Hidekatsu Wakizaka, Go Akamatsu, Taiga Yamaya, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Chika Igarashi …

Scientific Reports 10(1) 2020年3月10日
Comparative evaluation of [ ¹⁸ F]DiFA and its analogs as novel hypoxia positron emission tomography and [ ¹⁸ F]FMISO as the standard

Nakata, N., Kiriu, M., Okumura, Y., Zhao, S., Nishijima, K.-I., Shiga, T., Tamaki, N., Kuge, Y., Matsumoto, H.

Nuclear Medicine and Biology 70 2019年
Process development of [⁶⁴Cu]Cu-ATSM: efficient stabilization and sterilization for therapeutic applications

Matsumoto, H., Igarashi, C., Kaneko, E., Hashimoto, H., Suzuki, H., Kawamura, K., Zhang, M.-R., Higashi, T., Yoshii, Y.

Journal of Radioanalytical and Nuclear Chemistry 322(2) 2019年
⁶⁴Cu-intraperitoneal radioimmunotherapy: A novel approach for adjuvant treatment in a clinically relevant preclinical model of pancreatic cancer

Yoshii, Y., Matsumoto, H., Yoshimoto, M., Oe, Y., Zhang, M.-R., Nagatsu, K., Sugyo, A., Tsuji, A.B., Higashi, T.

Journal of Nuclear Medicine 60(10) 2019年
A Novel PET Probe “[ ¹⁸ F]DiFA” Accumulates in Hypoxic Region via Glutathione Conjugation Following Reductive Metabolism

Shimizu, Y., Zhao, S., Yasui, H., Nishijima, K.-I., Matsumoto, H., Shiga, T., Tamaki, N., Ogawa, M., Kuge, Y.

Molecular Imaging and Biology 21(1) 2019年

もっとみる

MISC

In vivo evaluation of local theranostic approach to high-grade glioma with hypoxiatargeting radiopharmaceutical 64Cu-ATSM

Yukie Yoshii, Fukiko Hihara, Hiroki Matsumoto, Chika Igarashi, Tomoko Tachibana, Mitsuhiro Shinada, Makoto Ohtake, Hisashi Suzuki, Ming-rong Zhang, Akito Oshima …

JOURNAL OF NUCLEAR MEDICINE 66 2025年6月1日
Phase I clinical trial of ⁶⁴Cu-ATSM for malignant brain tumors

Hiroaki Kurihara, Yoshitaka Narita, Kimiteru Ito, Hidemitsu Sato, Yasuji Miyakita, Masamichi Takahashi, Shunsuke Yanagisawa, Natsuko Tsuda Okita, Ryo Sadachi, Kensuke Tateishi …

JOURNAL OF CLINICAL ONCOLOGY 42(16) 2024年6月1日
再発悪性神経膠腫に対する治療用放射性薬剤64Cu-ATSMを用いたランダム化試験

成田善孝, 柳澤俊介, 伊藤公輝, 佐藤秀光, 吉井幸恵, 松本博樹, 栗原宏明

日本脳腫瘍学会学術集会プログラム・抄録集 41st 2023年
SPECT/PET/CT二核種同時測定を用いた腫瘍内血管分布・低酸素領域イメージング法の開発

吉井幸恵, 足立直也, 吉本光喜, 松本博樹, 古川高子, 張明栄, 犬伏正幸, 藤林靖久, 佐賀恒夫

JSMI Report 11(1) 22-24 2017年12月
Sensitized Cu-64-ATSM internal radiotherapy targeting tumor malignant regions: approach based on its biological characteristics

Yukie Yoshii, Takako Furukawa, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Yasushi Kiyono, Ming-Rong Zhang, Yasuhisa Fujibayashi, Tsuneo Saga

JOURNAL OF NUCLEAR MEDICINE 56(3) 2015年5月
Efficacy of Cu-64-ATSM internal radiotherapy against CD133(+) cancer stem cells in colon carcinoma: Improvement of therapeutic effect with nucleic acid antagonists

Yukie Yoshii, Takako Furukawa, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Ming-Rong Zhang, Yasushi Kiyono, Hiroshi Yoshii, Yasuhisa Fujibayashi, Tsuneo Saga

JOURNAL OF NUCLEAR MEDICINE 55 2014年5月

共同研究・競争的資金等の研究課題

64Cu-ATSM局所治療：切除困難な膠芽腫への革新的術中RI治療への挑戦

日本学術振興会科学研究費助成事業基盤研究(C) 2022年4月 - 2024年3月

檜原扶紀子, 立石健祐, 松本博樹, 五十嵐千佳, 吉井幸恵, 立花知子
難治性胆管がんの代謝を利用した新規放射性治療薬開発

日本学術振興会科学研究費助成事業基盤研究(B) 2022年4月 - 2024年3月

吉井幸恵, 松本博樹, 五十嵐千佳, 檜原扶紀子, 立花知子, 張明栄, 脇厚生

松本博樹

基本情報

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

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