Ritsuko Arai

Profile Information

Affiliation: Associate Professor/ Lecturer, Graduate School of Medicine, Nagoya University

Degree: 博士（学術）(東京大学)

J-GLOBAL ID: 201301022256873170
researchmap Member ID: B000233225

External link

Research Interests

Research Areas

Research History

2023 - Present

講師, 名古屋大学大学院医学系研究科総合保健学専攻
2015 - 2023

Fukushima Medical University
2021 - 2022

非常勤講師, 柔整科, 福島医療専門学校
2018 - 2020

非常勤講師, 福島県立総合衛生学院歯科衛生学科
2015 - 2016

Faculty of Science, Department of Life Science, Gakushuin University
2009 - 2015

National Institute of Genetics, National Institute of Genetics
2008 - 2010

School of Agriculture, Department of Life Sciences, Meiji University
2002 - 2009

基礎科学特別研究員、協力研究員, 吉田化学遺伝学研究室, 理化学研究所
2001 - 2002

研究員、基礎科学特別研究員, 脳科学総合研究センター, 理化学研究所

Papers

Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex

Reo Kurusu, Yuki Fujimoto, Hideaki Morishita, Daisuke Noshiro, Shuhei Takada, Koji Yamano, Hideaki Tanaka, Ritsuko Arai, Shun Kageyama, Tomoko Funakoshi …

Developmental Cell, 58(13) 1189-1205, Jul 10, 2023 Peer-reviewed
Phosphorylation of phase‐separated p62 bodies by ULK1 activates a redox‐independent stress response

Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu‐Hirota, Ritsuko Arai, Elena Ryzhii …

The EMBO Journal, 42(14) e113349, Jun 12, 2023 Peer-reviewed
Formulation of Chromatin Mobility as a Function of Nuclear Size during C. elegans Embryogenesis Using Polymer Physics Theories

Aiya K Yesbolatova, Ritsuko Arai, Takahiro Sakaue, Akatsuki Kimura

Physical Review Letters, 128(17) 178101-178101, Apr 29, 2022 Peer-reviewed
ERdj8 governs the size of autophagosomes during the formation process

Yo-hei Yamamoto, Ayano Kasai, Hiroko Omori, Tomoe Takino, Munechika Sugihara, Tetsuo Umemoto, Maho Hamasaki, Tomohisa Hatta, Tohru Natsume, Richard I. Morimoto …

Journal of Cell Biology, 219(8), Aug 3, 2020 Peer-reviewed
A unique kinesin-like protein, Klp8, is involved in mitosis and cell morphology through microtubule stabilization.

Jun Kashiwazaki, Yumi Yoneda, Tadashi Mutoh, Ritsuko Arai, Minoru Yoshida, Issei Mabuchi

Cytoskeleton (Hoboken, N.J.), 76(5) 355-367, May, 2019 Peer-reviewed
Improved Electron Microscopy Fixation Methods for Tracking Autophagy-Associated Membranes in Cultured Mammalian Cells

Arai R, Waguri S

Methods in Molecular Biology, 1880 211-221, Jan, 2019 Invited
Reduction in chromosome mobility accompanies nuclear organization during early embryogenesis in Caenorhabditis elegans

Ritsuko Arai, Takeshi Sugawara, Yuko Sato, Yohei Minakuchi, Atsushi Toyoda, Kentaro Nabeshima, Hiroshi Kimura, Akatsuki Kimura

Scientific Reports, 7(3631) 1-10, Jun, 2017 Peer-reviewed
A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation

Yuko Sato, Tomoya Kujirai, Ritsuko Arai, Haruhiko Asakawa, Chizuru Ohtsuki, Naoki Horikoshi, Kazuo Yamagata, Jun Ueda, Takahiro Nagase, Tokuko Haraguchi …

Journal of Molecular Biology, 428(20) 3885-3902, Oct, 2016 Peer-reviewed
Cell-Cycle Independent Chromosome Condensation in Schizosaccharomyces pombe Induced by High Hydrostatic Pressure Treatment

Seisuke Arai, Taketo Kawarai, Ritsuko Arai, Minoru Yoshida, Soichi Furukawa, Hirokazu Ogihara, Makari Yamasaki

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 73(9) 1956-1961, Sep, 2009 Peer-reviewed
Genome-wide approach for screening of functional genes causing overexpression-mediated growth inhibition in fission yeast Schizosaccharomyces pombe

Masaki I, Nishimura S, Yashiroda Y, Arai R, Yoshida M, Hamamoto M

Bulletin of the Faculty of Agriculture, Meiji University, 58(3) 85-90, Feb 27, 2009 Peer-reviewed
Global analysis of gel mobility of proteins and its use in target identification

Atsuko Shirai, Akihisa Matsuyama, Yoko Yashiroda, Atsushi Hashimoto, Yumi Kawamura, Ritsuko Arai, Yasuhiko Komatsu, Sueharu Horinouchi, Minoru Yoshida

JOURNAL OF BIOLOGICAL CHEMISTRY, 283(16) 10745-10752, Apr, 2008 Peer-reviewed
Cessation of cytokinesis in Schizosaccharomyces pombe during growth after release from high hydrostatic pressure treatment

Seisuke Arai, Taketo Kawarai, Ritsuko Arai, Minoru Yoshida, Soichi Furukawa, Hirokazu Ogihara, Makari Yamasaki

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 72(1) 88-93, Jan, 2008 Peer-reviewed
ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe

Akihisa Matsuyama*, Ritsuko Arai*, Yoko Yashiroda*, Atsuko Shirai, Ayako Kamata, Shigeko Sekido, Yumiko Kobayashi, Atsushi Hashimoto, Makiko Hamamoto, Yasushi Hiraoka …

NATURE BIOTECHNOLOGY, 24(7) 841-847, Jul, 2006 Peer-reviewedLead author
Small GTPase Rho5 is a functional homologue of Rho1, which controls cell shape and septation in fission yeast

K Nakano, R Arai, Mabuchi, I

FEBS LETTERS, 579(23) 5181-5186, Sep, 2005 Peer-reviewed
Directionality of F-actin cables changes during the fission yeast cell cycle

T Kamasaki, R Arai, M Osumi, Mabuchi, I

NATURE CELL BIOLOGY, 7(9) 916-917, Sep, 2005 Peer-reviewed
The small GTPase Rho4 is involved in controlling cell morphology and septation in fission yeast

Kentaro Nakano, Tadashi Mutoh, Ritsuko Arai, Issei Mabuchi

Genes to Cells, 8(4) 357-370, Apr 1, 2003 Peer-reviewed
The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast

K Nakano, J Imai, R Arai, A Toh-e, Y Matsui, Mabuchi, I

JOURNAL OF CELL SCIENCE, 115(23) 4629-4639, Dec, 2002 Peer-reviewed
F-actin ring formation and the role of F-actin cables in the fission yeast Schizosaccharomyces pombe

R Arai, Mabuchi, I

JOURNAL OF CELL SCIENCE, 115(5) 887-898, Mar, 2002 Peer-reviewed
Comparative genomic hybridization study of genetic changes associated with vindesine resistance in esophageal carcinoma

K Obara, M Ghazizadeh, H Shimizu, R Arai, T Tenjin, S Suzuki, Y Moriyama, O Kawanami

INTERNATIONAL JOURNAL OF ONCOLOGY, 20(2) 255-260, Feb, 2002 Peer-reviewed
Contractile ring formation in Xenopus egg and fission yeast

T Noguchi, R Arai, F Motegi, K Nakano, Mabuchi, I

CELL STRUCTURE AND FUNCTION, 26(6) 545-554, Dec, 2001

Misc.

ER-related structure mediates isolation membrane organization

Arai R, Waguri S

272(9) 20453-20458, Feb 29, 2020 Invited
本格的リバースプロテオミクス時代の到来：分裂酵母全タンパク質解析系の確立とその応用

荒井律子, 吉田稔

化学と生物, 45(5) 303-305, May, 2007 Invited
Global analysis of proteins in fission yeast : from ORFeome to localizome and beyond

ARAI Ritsuko, MATSUYAMA Akihisa, YASHIRODA Yoko, YOSHIDA Minoru

Bioscience & industry, 64(12) 687-691, Dec, 2006 Invited
Rapid and reliable preparation of total cell lysates from fission yeast.

Shirai, A, matsuyama, A, Yashiroda, Y, Arai, R, Yoshida, M

Nat. Protocols, Jul 21, 2006

Presentations

ピースミールマイトファジーの微細形態解析－小胞体に繋がる隔離膜はミトコンドリア表面に密着する

和栗聡, 荒井律子, 山下俊一, Benjamin Padman, Gediminas Gervinskas, Michael Lazarou, 神吉智丈

第129回日本解剖学会総会・全国学術集会, Mar 23, 2024
Ultrastructural analysis on the process of isolation membrane formation during piecemeal mitophagy

Arai R, Yamashita SI, Sugisaki T, Huajui W, Kanki T, Waguri S

The 78th Annual Meeting of The Japanese Society of Microscopy, May 12, 2022 Invited
ピースミールマイトファジー隔離膜形成プロセスの微細形態学的解析

荒井律子, 山下俊一, 杉崎達也, Wu Huajui, 神吉智丈, 和栗聡

第44回日本分子生物学会年会, Dec 1, 2021 Invited
ピースミールマイトファジー隔離膜構築プロセスの電子顕微鏡解析

荒井律子, 山下俊一, 杉崎達也, Wu Huajui, 神吉智丈, 和栗聡

日本解剖学会第67回東北・北海道連合支部学術集会, Sep 4, 2021
Ultrastructural analysis on the process of isolation membrane formation during piecemeal mitophagy

Mar 29, 2021 Invited
Ultrastructural analysis on isolation membrane formation during partial mitophagy

Ritsuko Arai, Shun-ichi Yamashita, Tomotake Kanki, Satoshi Waguri

The 9th International Symposium on Autophagy, Nov 5, 2019
ミトコンドリア構造の一部を隔離するマイトファジーの微細形態学的プロセス

荒井律子, 山下俊一, 神吉智丈, 和栗聡

第12 回オートファジー研究会・第1 回新学術領域研究「マルチモードオートファジー」班会議プログラム, Oct 26, 2019
マイトファジー隔離膜の微細構造解析

和栗聡, 荒井律子

第124回日本解剖学会総会全国学術集会, Mar 29, 2019
ミトコンドリア構造の一部分を自食するマイトファジープロセスの微細形態学的解析

荒井律子, 山下俊一, 神吉智丈, 和栗聡

第124回日本解剖学会総会全国学術集会, Mar 27, 2019
鉄欠乏性マイトファジーにおける隔離膜形成過程の微細形態解析

荒井律子, 山下俊一, 神吉智丈, 和栗聡

第11回オートファジー研究会, Nov 19, 2018
Mitophagic isolation membrane visualized by CLEM analysis

Arai R, Yamashita SI, Kanki T, Waguri S

XXVI International Symposium on Morphological Sciences, Jul 5, 2018
鉄キレート剤 deferiprone 誘導マイトファジーにおける隔離膜形成過程の微細形態解析

荒井律子, 和栗聡

第123回日本解剖学会総会・全国学術集会, Mar 28, 2018
Correlative light and electron microscopy (CLEM) analysis on isolation membrane formation during deferiprone-induced mitophagy

Ritsuko Arai, Shun-ichi Yamashita, Tomotake Kanki, Satoshi Waguri

A3 Conference on Autophagy, Feb 28, 2018
哺乳類細胞オートファゴソーム形成過程における膜構造変化の解析

荒井律子, 和栗聡

日本解剖学会題63回東北・北海道連合支部学術集会, Sep 9, 2017
線虫配偶子形成過程と受精後の細胞核におけるヒストン修飾変化のライブイメージング解析

荒井律子, 佐藤優子, 木村宏, 木村暁

第37回日本分子生物学会年会, Nov 25, 2014
核-細胞質間輸送を介した分裂酵母微小管ネットワーク形成の制御

荒井律子, 鎌田綾子, 佐藤政充, 木村暁, 登田隆, 吉田稔

第47回酵母遺伝学フォーラム, Sep 1, 2014
受精から多細胞化の進行に伴う核内環境の変化とその影響下におけるクロマチンのふるまい

荒井律子, 菅原武志, 佐藤優子, 鍋島建太郎, 木村宏, 木村暁

第66回日本細胞生物学会大会, Jun 11, 2014 Invited
線虫初期発生ステージにおける核内構成化の可視的解析

荒井律子, 佐藤優子, 菅原武志, 鍋島建太郎, 木村宏, 木村暁

第36回日本分子生物学会年会, Dec 3, 2013
線虫初期胚核内構成過程におけるクロマチン動態変化の4次元定量解析

荒井律子, 菅原武志, 鍋島建太郎, 木村宏, 木村暁

第65回日本細胞生物学会大会, Jun 19, 2013
クロマチン動態変化を指標とした核内構成化メカニズムの解析

荒井律子, 菅原武志, 鍋島建太郎, 木村宏, 木村暁

第30回染色体ワークショップ・第11回核ダイナミクス研究会, Dec 19, 2012

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