2020年5月27日
Activatable fluorescent probes for hydrolase enzymes based on coumarin-hemicyanine hybrid fluorophores with large Stokes shifts.
Chemical communications (Cambridge, England)
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- 巻
- 56
- 号
- 42
- 開始ページ
- 5617
- 終了ページ
- 5620
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/d0cc00559b
- 出版者・発行元
- Royal Society of Chemistry ({RSC})
We show that the equilibrium of intramolecular spirocyclization of coumarin-hemicyanine hybrid fluorophores can be finely tuned by means of chemical modifications. We used this scaffold to develop activatable fluorescent probes with large Stokes shifts for γ-glutamyltranspeptidase and esterase.
- ID情報
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- DOI : 10.1039/d0cc00559b
- ORCIDのPut Code : 72197019
- PubMed ID : 32297612