2020年11月7日
Design of spontaneously blinking fluorophores for live-cell super-resolution imaging based on quantum-chemical calculations.
Chemical communications (Cambridge, England)
- 巻
- 56
- 号
- 86
- 開始ページ
- 13173
- 終了ページ
- 13176
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/d0cc05126h
Spontaneously blinking fluorophores are powerful tools for live-cell super-resolution imaging under physiological conditions. Here we show that quantum-chemical calculations can predict key parameters for fluorophore design. We applied this methodology to develop a spontaneously blinking fluorophore with yellow fluorescence for super-resolution imaging of microtubules in living cells.
- ID情報
-
- DOI : 10.1039/d0cc05126h
- PubMed ID : 33020769