1996
Involvement of Vulnibactin and Exocellular Protease in Utilization of Transferrin- and Lactoferrin-Bound Iron by Vibrio vulnificus
Japanese Journal of Microbiology
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- Volume
- 40
- Number
- 8
- First page
- 595
- Last page
- 598
- Language
- English
- Publishing type
- Publisher
- Center For Academic Publications Japan
In vitro growth experiments were conducted to evaluate the ability of vulnibactin, a siderophore produced by Vibrio vulnificus, to sequester transferrin- or lactoferrin-bound iron for growth. Comparative studies with the strain producing vulnibactin and its exocellular protease-deficient mutant revealed the involvement of the protease in addition to vulnibactin in effective utilization of iron ion (Fe3+) bound to transferrin and lactoferrin. It appears that the protease causes cleavage of these proteins, thereby making bound iron more accessible to vulnibactin.
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- ID information
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- ISSN : 0385-5600
- CiNii Articles ID : 130003484407