Masatoshi Yamazaki

J-GLOBAL         Last updated: Apr 8, 2019 at 16:46
 
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Name
Masatoshi Yamazaki
E-mail
yamazakiriem.nagoya-u.ac.jp
URL
http://www.bmpe.t.u-tokyo.ac.jp/en/index.html
Affiliation
The University of Tokyo
Section
Medical Device Development and Regulation Research Center
Job title
Associate Professor
Degree
MD, PhD
Other affiliation
Brown University
Research funding number
30627328

Profile

Since about 100 years ago, many theoretical and experimental studies have suggested that rotor (a.k.a. 2-dimensional spiral wave reentry/3-d scroll wave) rotating around a functional obstacle, like hurricane and tornado, is the major mechanisms of cardiac fibirillation. Our objectives are first to explore spiral wave dynamics specifically in remodeled atria of chronic atrial fibrillation using high resolution optical mapping system and computer simulation; and second to examine how radio-frequency ablation of spiral wave effectively terminates and prevents cardiac fibrillation.

Research Areas

 
 

Academic & Professional Experience

 
Apr 2019
 - 
Today
Associate Professor, Medical Device Development and Regulation Research Center, The University of Tokyo
 
Apr 2017
 - 
Mar 2019
Chief Scientist, Assistant Professor, Medical Device Development and Regulation Research Center, The University of Tokyo
 
Feb 2017
 - 
Today
Visiting Assistant Professor, Cardiovascular Research Center, Rhode Island Hospital and Brown University
 
Apr 2016
 - 
Mar 2019
JSPS Scientist for International Research, Japan Society for the Promotion of Science
 
Apr 2013
 - 
Mar 2017
Assistant Professor, RIEM, Nagoya University
 
Aug 2011
 - 
Mar 2013
Research Fellow, RIEM, Nagoya University
 
Apr 2008
 - 
Jul 2011
Research Associate, Center for Arrhythmia Research, University of Michigan
 
Sep 2006
 - 
Mar 2008
Post-doc research associate, Dept. of Pharmacology, SUNY Uptstate Medical University
 
Apr 2006
 - 
Aug 2006
Medical Manager, Mitsubishi Nagoya Hospiral
 
Apr 1999
 - 
Mar 2003
Attending Staff, Shizuoka Saiseikai General Hospital
 
Apr 1997
 - 
Mar 1999
Resident, Shizuoka Saiseikai General Hospital
 

Education

 
Apr 2002
 - 
Mar 2006
Nagoya University Graduate School of Medicine
 
Apr 1991
 - 
Mar 1997
Kawasaki Medical School
 

Committee Memberships

 
2016
 - 
Today
The Japanese Heart Rhythm Society  Councilor
 

Awards & Honors

 
Sep 2011
Role of the Left Atrial Anatomy in the Maintenance of Three-Dimensional Scroll Waves in Acute, Stretch-Related and Cholinergic Atrial Fibrillation, Young Investigator Award (1st prize), Asia Pacific Heart Rhythm Society
 
May 2010
Mechanisms of stretch-induced atrial fibrillation in the presence and the absence of adrenocholinergic stimulation: interplay between rotors and focal discharges., Heart Rhythm Journal Award 2010, Heart Rhythm Society, USA
 
Oct 2007
Destabilization and Early Termination of Spiral-wave Reentry by a Class III Antiarrhythmic Agent, Nifekalant, in a Perfused 2-Dimensional Layer of Rabbit Ventricular Myocardium, Young Investigator Award (1st prize), The Japanese Society of Electrocardiology
 
Jul 2007
Mechanisms of stretch-induced atrial fibrillation in the presence and the absence of adrenocholinergic stimulation: interplay between rotors and focal discharges., Heart Rhythm Society Fellowship Award, Heart Rhythm Society, USA
 

Published Papers

 
Nielsen JB, Thorolfsdottir RB, Fritsche LG, Zhou W, Skov MW, Graham SE, Herron TJ, McCarthy S, Schmidt EM, Sveinbjornsson G, Surakka I, Mathis MR, Yamazaki M, Crawford RD, Gabrielsen ME, Skogholt AH, Holmen OL, Lin M, Wolford BN, Dey R, Dalen H, Sulem P, Chung JH, Backman JD, Arnar DO, Thorsteinsdottir U, Baras A, O'Dushlaine C, Holst AG, Wen X, Hornsby W, Dewey FE, Boehnke M, Kheterpal S, Mukherjee B, Lee S, Kang HM, Holm H, Kitzman J, Shavit JA, Jalife J, Brummett CM, Teslovich TM, Carey DJ, Gudbjartsson DF, Stefansson K, Abecasis GR, Hveem K, Willer CJ
Nature genetics      Jul 2018   [Refereed]
Tomii N, Yamazaki M, Arafune T, Kamiya K, Nakazawa K, Honjo H, Shibata N, Sakuma I
American journal of physiology. Heart and circulatory physiology      Mar 2018   [Refereed]
Avula UMR, Hernandez JJ, Yamazaki M, Valdivia CR, Chu A, Rojas-Pena A, Kaur K, Ramos-Mondragón R, Anumonwo JM, Nattel S, Valdivia HH, Kalifa J
Circulation. Arrhythmia and electrophysiology   11(3) e005659   Mar 2018   [Refereed]
Ogawa T, Honjo H, Yamazaki M, Kushiyama Y, Sakuma I, Kodama I, Kamiya K
Circulation journal : official journal of the Japanese Circulation Society      May 2017   [Refereed]
Seitz J, Bars C, Théodore G, Beurtheret S, Lellouche N, Bremondy M, Ferracci A, Faure J, Penaranda G, Yamazaki M, Avula UM, Curel L, Siame S, Berenfeld O, Pisapia A, Kalifa J
Journal of the American College of Cardiology   69(3) 303-321   Jan 2017   [Refereed]
Association of left atrial phasic volumes with systemic arterial stiffness and ankle-brachial index in hypertensive patients
Iida M, Yamamoto M, Ishiguro Y, Yamazaki M, Ueda N, Honjo H, Kamiya K
J Hum Hypertens   31 270-277   Apr 2017   [Refereed]
Takanari H, Bourgonje VJ, Fontes MS, Raaijmakers AJ, Driessen H, Jansen JA, van der Nagel R, Kok B, van Stuijvenberg L, Boulaksil M, Takemoto Y, Yamazaki M, Tsuji Y, Honjo H, Kamiya K, Kodama I, Anderson ME, van der Heyden MA, van Rijen HV, van Veen TA, Vos MA
Cardiovascular research   111(4) 410-421   Sep 2016   [Refereed]
Kushiyama Y, Honjo H, Niwa R, Takanari H, Yamazaki M, Takemoto Y, Sakuma I, Kodama I, Kamiya K
American journal of physiology. Heart and circulatory physiology   311(3) H750-8   Sep 2016   [Refereed]
Yamada C, Kuwahara K, Yamazaki M, Nakagawa Y, Nishikimi T, Kinoshita H, Kuwabara Y, Minami T, Yamada Y, Shibata J, Nakao K, Cho K, Arai Y, Honjo H, Kamiya K, Nakao K, Kimura T
Cardiovascular research      Nov 2015   [Refereed]
Tomii N, Yamazaki M, Arafune T, Honjo H, Shibata N, Sakuma I
IEEE transactions on bio-medical engineering      Nov 2015   [Refereed]
Yamazaki M, Avula UM, Berenfeld O, Kalifa J
Journal of the American College of Cardiology EP   1(4) 256-269   Aug 2015   [Refereed]
Optical Mapping with a Precise Image Registration to Observe Late Phase 3 EAD
Hernandez I, Arafune T, Shibata N, Yamazaki M, Honjo H, Sakuma I
Journal of Medical and Bioengineering   4    Feb 2015   [Refereed]
Iida M, Yamamoto M, Ishiguro YS, Yamazaki M, Ueda N, Honjo H, Kamiya K
Journal of diabetes and its complications      Aug 2014   [Refereed]
Berenfeld O, Yamazaki M, Filgueiras-Rama D, Kalifa J
Methods of information in medicine   53 314-319   2014   [Refereed]
Iida M, Yamamoto M, Ishiguro YS, Yamazaki M, Ueda N, Honjo H, Kamiya K
Clinica chimica acta; international journal of clinical chemistry   425 259-264   Oct 2013   [Refereed]
Yamazaki M, Avula UM, Bandaru K, Atreya A, Boppana VS, Honjo H, Kodama I, Kamiya K, Kalifa J
Heart rhythm : the official journal of the Heart Rhythm Society      Feb 2013   [Refereed]
Filgueiras-Rama D, Price NF, Martins RP, Yamazaki M, Avula UM, Kaur K, Kalifa J, Ennis SR, Hwang E, Devabhaktuni V, Jalife J, Berenfeld O
Circulation. Arrhythmia and electrophysiology      Oct 2012   [Refereed]
Yamazaki M, Filgueiras-Rama D, Berenfeld O, Kalifa J
Progress in biophysics and molecular biology   110(2-3) 269-277   Oct 2012   [Refereed]
Takemoto Y, Takanari H, Honjo H, Ueda N, Harada M, Kato S, Yamazaki M, Sakuma I, Opthof T, Kodama I, Kamiya K
American journal of physiology. Heart and circulatory physiology   303 H578-86   Sep 2012   [Refereed]
Yamazaki M and Jalife J
Journal of Arrhythmia   28(3) 129-139   Aug 2012   [Refereed][Invited]
Iida M, Yamamoto M, Ishiguro Y, Yamazaki M, Honjo H, Kamiya K
Journal of the American Society of Hypertension : JASH   6 261-269   Jul 2012   [Refereed]
Filgueiras-Rama D, Martins RP, Mironov S, Yamazaki M, Calvo CJ, Ennis SR, Bandaru K, Noujaim SF, Kalifa J, Berenfeld O, Jalife J
Circulation. Arrhythmia and electrophysiology   5 561-570   Jun 2012   [Refereed]
Yamazaki M, Mironov S, Taravant C, Brec J, Vaquero LM, Bandaru K, Avula UM, Honjo H, Kodama I, Berenfeld O, Kalifa J
Cardiovascular research   94(1) 48-57   Apr 2012   [Refereed]
Yamazaki M, Honjo H, Ashihara T, Harada M, Sakuma I, Nakazawa K, Trayanova N, Horie M, Kalifa J, Jalife J, Kamiya K, Kodama I
Heart rhythm : the official journal of the Heart Rhythm Society   9 107-114   Jan 2012   [Refereed]
Kalifa J, Yamazaki M
Journal of the American College of Cardiology   58 2116-2117   Nov 2011   [Refereed]
Berenfeld O, Ennis S, Hwang E, Hooven B, Grzeda K, Mironov S, Yamazaki M, Kalifa J, Jalife J
Heart rhythm : the official journal of the Heart Rhythm Society   8 1758-1765   Nov 2011   [Refereed]
Filgueiras-Rama D, Martins RP, Ennis SR, Mironov S, Jiang J, Yamazaki M, Kalifa J, Jalife J, Berenfeld O
Journal of visualized experiments : JoVE      Jul 2011   [Refereed]
Castaño A, Crawford T, Yamazaki M, Avula UM, Kalifa J
Heart rhythm : the official journal of the Heart Rhythm Society      Jul 2011   [Refereed]
Pandit SV, Zlochiver S, Filgueiras-Rama D, Mironov S, Yamazaki M, Ennis SR, Noujaim SF, Workman AJ, Berenfeld O, Kalifa J, Jalife J
Cardiovascular research   89(4) 843-851   Mar 2011   [Refereed]
Yamazaki M, Morgenstern S, Klos M, Campbell K, Buerkel D, Kalifa J
Heart rhythm : the official journal of the Heart Rhythm Society   7 1501-1508   Oct 2010   [Refereed]
Nakagawa H, Honjo H, Ishiguro YS, Yamazaki M, Okuno Y, Harada M, Takanari H, Sakuma I, Kamiya K, Kodama I
Heart and vessels   25(4) 338-347   Jul 2010   [Refereed]
Iida M, Maeda H, Yamamoto M, Yamazaki M, Honjo H, Kodama I, Kamiya K
American journal of hypertension   23 197-201   Feb 2010   [Refereed]
Yamazaki M, Vaquero LM, Hou L, Campbell K, Zlochiver S, Klos M, Mironov S, Berenfeld O, Honjo H, Kodama I, Jalife J, Kalifa J
Heart rhythm : the official journal of the Heart Rhythm Society   6 1009-1017   Jul 2009   [Refereed]
Ishiguro YS, Honjo H, Opthof T, Okuno Y, Nakagawa H, Yamazaki M, Harada M, Takanari H, Suzuki T, Morishima M, Sakuma I, Kamiya K, Kodama I
Heart rhythm : the official journal of the Heart Rhythm Society   6 684-692   May 2009   [Refereed]
Klos M, Calvo D, Yamazaki M, Zlochiver S, Mironov S, Cabrera JA, Sanchez-Quintana D, Jalife J, Berenfeld O, Kalifa J
Circulation. Arrhythmia and electrophysiology   1 175-183   Aug 2008   [Refereed]
Zlochiver S, Yamazaki M, Kalifa J, Berenfeld O
Heart rhythm : the official journal of the Heart Rhythm Society   5 846-854   Jun 2008   [Refereed]
Harada M, Honjo H, Yamazaki M, Nakagawa H, Ishiguro YS, Okuno Y, Ashihara T, Sakuma I, Kamiya K, Kodama I
American journal of physiology. Heart and circulatory physiology   294 H1896-905   Apr 2008   [Refereed]
Iida M, Nihei M, Yamazaki M, Sawaguchi M, Honjo H, Kodama I, Kamiya K
Journal of human hypertension   22 275-281   Apr 2008   [Refereed]
Sato T, Ohkusa T, Honjo H, Suzuki S, Yoshida MA, Ishiguro YS, Nakagawa H, Yamazaki M, Yano M, Kodama I, Matsuzaki M
American journal of physiology. Heart and circulatory physiology   294 H1164-73   Mar 2008   [Refereed]
Tanaka K, Zlochiver S, Vikstrom KL, Yamazaki M, Moreno J, Klos M, Zaitsev AV, Vaidyanathan R, Auerbach DS, Landas S, Guiraudon G, Jalife J, Berenfeld O, Kalifa J
Circulation research   101 839-847   Oct 2007   [Refereed]
Kalifa J, Klos M, Zlochiver S, Mironov S, Tanaka K, Ulahannan N, Yamazaki M, Jalife J, Berenfeld O
Heart rhythm : the official journal of the Heart Rhythm Society   4 916-924   Jul 2007   [Refereed]
Iida M, Yamazaki M, Honjo H, Kodama I, Kamiya K
Journal of human hypertension   21 551-557   Jul 2007   [Refereed]
Yamazaki M, Honjo H, Nakagawa H, Ishiguro YS, Okuno Y, Amino M, Sakuma I, Kamiya K, Kodama I
American journal of physiology. Heart and circulatory physiology   292 H539-48   Jan 2007   [Refereed]
Honjo H, Yamazaki M, Kamiya K, Kodama I
Circulation journal : official journal of the Japanese Circulation Society   71(SupplementA) A26-A31   2007   [Refereed]
Amino M, Yoshioka K, Tanabe T, Tanaka E, Mori H, Furusawa Y, Zareba W, Yamazaki M, Nakagawa H, Honjo H, Yasui K, Kamiya K, Kodama I
Cardiovascular research   72 412-421   Dec 2006   [Refereed]
Yamazaki M, Osaka T, Yokoyama E, Kodama I
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   17 35-40   Oct 2006   [Refereed]
Amino M, Yamazaki M, Nakagawa H, Honjo H, Okuno Y, Yoshioka K, Tanabe T, Yasui K, Lee JK, Horiba M, Kamiya K, Kodama I
Circulation journal : official journal of the Japanese Circulation Society   69(5) 576-584   May 2005   [Refereed]
Osaka T, Yamazaki M, Yokoyama E, Ito A, Kodama I
Journal of cardiovascular electrophysiology   15 877-884   Aug 2004   [Refereed]

Books etc

 
Arrhythmia 2017
Yamazaki M, Kodama I (Part:Contributor, Mechanisms of atrial fibrillation -optical mapping-)
2017   
In Cardiac Electrophysiology: From Cell to Bedside 6th Edition edited by Zipes DP and Jalife J
Kalifa J, Avula U and Yamazaki M (Part:Contributor, Acute atrial ischemia and fibrillation.)
ELSEVIER SAUNDERS   Sep 2014   
Is driver ablation for persistent atrial fibrillation effective or not?
Masatoshi Yamazaki (Part:Contributor)
Nikkei Business Publications, Inc.   Aug 2014   
Is FIRM (Rotor and Focal impulse) ablation for atrial fibrillation effective or not? (What's New in Electrocardiology by JSE)
Masatoshi Yamazaki (Part:Contributor)
Nikkei Business Publications, Inc.   Jun 2013   
Arrhythmia+PLUS No.5
Masatoshi Yamazaki and Itsuo Kodama (Part:Contributor, Mechanisms of atrial fibrillation maintenance by using optical mapping)
Life Science Publishing   Sep 2012   
Cardiac Mechano-Electric Coupling & Arrhythmias 2nd Edition.
Masatoshi Yamazaki and Jerome Kalifa (Part:Contributor, Stretch effects on fibrillation dynamics.)
OXFORD UNIVERSITY PRESS   Oct 2011   

Research Grants & Projects

 
Mechanical stretch and fibrillation dynamics in the left atrium
Heart Rhythm Society, USA: Fellowship Award of Heart Rhythm Society
Project Year: 2007 - 2008    Investigator(s): Masatoshi Yamazaki

Patents

 
US2008/0195161 A1 : Ventricular Fibrillation Preventing Apparatus and Defibrillating Apparatus
Ichiro Sakuma, Itsuo Kodama, Kaichiro Kamiya, Haruo Honjo, Masatoshi Yamazaki, Takashi Ashihara, Kazuo Nakazawa