基本情報

所属
厚生労働省 国立感染症研究所 細菌第一部 口腔細菌感染症室 主任研究官
ウメオ大学 医学部 分子生物学 Guest Researcher
学位
博士 (歯学)(東京医科歯科大学大学院)
D.D.S.(Hokkaido University)

J-GLOBAL ID
200901094097758088

外部リンク

Born in Tokyo (Japan), Ryoma Nakao is a Senior Research Scientist at Laboratory of Oral Bacterial Infection, Department of Bacteriology I, National Institute of Infectious Diseases (NIID). NIID is a research institute attached to Ministry of Health, Labour and Welfare, Japan. He has been working in NIID since 2003, and leading his research group since 2010.

Nakao's main research area is immunopathology and ethiology of periodontal diseases caused by periodontopathic bacteria including Porphyomonas gingivalis, but is now expanding to development of effective treatment and prevention against not only oral pathogens, but also intestinal and respiratory tract pahogens such as Escherichia coli, Streptococcus pneumoniae, etc. His research group is now pursuing establishment of intranasal vaccine system using Bacterial Membrane Vesicles (BMVs) and development of antimicrobial or anti-biofilm agents.

Our current research topics and recent achievements:

1. Molecular Mechanisims of BMV Biogenesis in Various Life Stages of Bacteria
(Microb Biotechnol. 2020. Hirayama et al.) (Front Microbiol. 2018. Nakao et al.) (Infect Immun. 2017. Obana et al.) (PLoS One. 2012. Nakao et al.)

2. Intranasal Vaccine System Using BMVs of Porphyromonas gingivalis for Prospect Applications to Periodontitis
(Vaccine. 2016. Nakao et al.) (Pathog Dis. 2015. Bai et al.) (PLoS One. 2014. Nakao et al.) (Microb Infect. 2014. Nakao et al.) (PLoS One. 2011. Nakao et al.)

3. Seeking Anti-microbial/Anti-biofilm Compounds from a Wide Range of Natural Products
(Odontol. 2020. Nakao et al.) (J Dent Res. 2018. Yoshimasu et al.) (J Periodont Res. 2017. Kariu et al.)

4. A Series of Clinical Trials: Microbiological Effect of Topical Application of Natural Products to Oral Cavity
(Recent 3 randomized, controlled clinical trials led by Dr. Nakao as a pricipal investigator are published as nos. UMIN000013850, UMIN000023016, UMIN000025174 in a clinical trial registry in Japan, UMIN-CTR.

 

Nakao was scheduled to organize the EMBO Workshop in Autumn, 2020. However, due to the spread of the novel coronavirus (SARS-CoV-2), this Workshops has been postponed in Autumn, 2021. See below.
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EMBO Workshop: Bacterial membrane vesicles | Biogenesis, functions and medical applications
Dates: 24 November – 26 November, 2021 (New Dates!)
Place: Tsukuba International Congress Center, Japan
Websites:   http://events.embo.org/coming-soon/index.php?EventID=w20-52

Organizing committee
   Contact: Ryoma Nakao
   Email: embows@procom-i.jp
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論文

  32

MISC

  9

書籍等出版物

  4

講演・口頭発表等

  84

共同研究・競争的資金等の研究課題

  32