Ryo Okamoto

J-GLOBAL         Last updated: Nov 11, 2019 at 16:31
 
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Name
Ryo Okamoto
Affiliation
Osaka University
Section
Graduate School of ScienceDepartment of Chemistry

Research Areas

 
 

Academic & Professional Experience

 
Jul 2017
 - 
Today
Associate Professor, Department of Chemistry, Graduate School of Science, Osaka University
 
Sep 2009
 - 
Jun 2017
Assistant Professor, Department of Chemistry, Graduate of School, Osaka University
 
Aug 2009
 - 
Aug 2010
Postdoctoral Fellow for Research Abroad, JSPS, The University of Chicago
 
Apr 2009
 - 
Jul 2009
Specially Appointed Researcher, Department of Chemistry, Graduate School of Science, Osaka Universiity
 

Education

 
Apr 2006
 - 
Mar 2009
Yokoham City University
 
Apr 2004
 - 
Mar 2006
Yokohama City University
 
Apr 2000
 - 
Mar 2004
School of Science, Yokohama City University
 

Committee Memberships

 
2018
 - 
Today
International Journal of Peptide Research and Therapeutics  Editorial board
 

Awards & Honors

 
2015
Incentive Award of Japanese Society of Carbohydrate Research, Japanese Society of Carbohydrate Research
 
2012
Chemical Society of Japan Presentation Award 2012, Chemical Society of Japan
 

Published Papers

 
Okamoto R, Haraguchi T, Nomura K, Maki Y, Izumi M, Kajihara Y
Biochemistry   58(12) 1672-1678   Mar 2019   [Refereed]
Chandrashekar C, Okamoto R, Izumi M, Kajihara Y
Chemistry (Weinheim an der Bergstrasse, Germany)   25(43) 10197-10203   Aug 2019   [Refereed]
Okamoto R, Ono E, Izumi M, Kajihara Y
Frontiers in chemistry   7 173   Mar 2019   [Refereed]
Ryo Okamoto, Kota Nomura, Yuta Maki, Yasuhiro Kajihara
Chemistry Letters   48 1391-1393   Jan 2019
© 2019 The Chemical Society of Japan | 1391 Enzymes and ribosomes accurately form peptide bonds without protecting groups in vivo. Inspired by biological chemistries, we have been exploring a chemoselective reaction for peptide bond formation. In ...
Kiuchi T, Izumi M, Mukogawa Y, Shimada A, Okamoto R, Seko A, Sakono M, Takeda Y, Ito Y, Kajihara Y
Journal of the American Chemical Society   140(50) 17499-17507   Dec 2018   [Refereed]
Maki Y, Mima T, Okamoto R, Izumi M, Kajihara Y
The Journal of organic chemistry   83(1) 443-451   Jan 2018   [Refereed]
Izumi M, Kuruma R, Okamoto R, Seko A, Ito Y, Kajihara Y
Journal of the American Chemical Society   139(33) 11421-11426   Aug 2017   [Refereed]
Orii R, Sakamoto N, Fukami D, Tsuda S, Izumi M, Kajihara Y, Okamoto R
Chemistry (Weinheim an der Bergstrasse, Germany)   23(39) 9253-9257   Jul 2017   [Refereed]
Minh Hien N, Izumi M, Sato H, Okamoto R, Kajihara Y
Chemistry (Weinheim an der Bergstrasse, Germany)   23(27) 6579-6585   May 2017   [Refereed]
Izumi M, Komaki S, Okamoto R, Seko A, Takeda Y, Ito Y, Kajihara Y
Organic & biomolecular chemistry   14(25) 6088-6094   Jul 2016   [Refereed]
Izumi M, Oka Y, Okamoto R, Seko A, Takeda Y, Ito Y, Kajihara Y
Angewandte Chemie (International ed. in English)   55(12) 3968-3971   Mar 2016   [Refereed]
Okamoto R, Isoe M, Izumi M, Kajihara Y
Journal of peptide science : an official publication of the European Peptide Society   22(5) 343-351   May 2016   [Refereed]
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY   29(165) E1-E10   Jan 2017   [Refereed]
Maki Y, Okamoto R, Izumi M, Murase T, Kajihara Y
Journal of the American Chemical Society   138(10) 3461-3468   Mar 2016   [Refereed]
Murakami M, Kiuchi T, Nishihara M, Tezuka K, Okamoto R, Izumi M, Kajihara Y
Science advances   2(1) e1500678   Jan 2016   [Refereed]
Kajihara Y, Kanemitsu Y, Nishihara M, Okamoto R, Izumi M
Journal of peptide science : an official publication of the European Peptide Society   20(12) 958-963   Dec 2014   [Refereed]
Okamoto R, Mandal K, Ling M, Luster AD, Kajihara Y, Kent SB
Angewandte Chemie (International ed. in English)   53(20) 5188-5193   May 2014   [Refereed]
Okamoto R, Mandal K, Sawaya MR, Kajihara Y, Yeates TO, Kent SB
Angewandte Chemie (International ed. in English)   53(20) 5194-5198   May 2014   [Refereed]
Okamoto R, Kimura M, Ishimizu T, Izumi M, Kajihara Y
Chemistry (Weinheim an der Bergstrasse, Germany)   20(33) 10425-10430   Aug 2014   [Refereed]
Izumi M, Otsuki A, Nishihara M, Okamoto R, Kajihara Y
Chembiochem : a European journal of chemical biology   15(17) 2503-2507   Nov 2014   [Refereed]
Izumi M, Murakami M, Okamoto R, Kajihara Y
Journal of peptide science : an official publication of the European Peptide Society   20(2) 98-101   Feb 2014   [Refereed]
Okamoto R, Izumi M, Kajihara Y
Current opinion in chemical biology   22 92-99   Oct 2014   [Refereed]
Kajihara Y, Tanabe Y, Sasaoka S, Okamoto R
Chemistry (Weinheim an der Bergstrasse, Germany)   18(19) 5944-5953   May 2012   [Refereed]
Morishita Yasuhito, Kaino Tomoka, Okamoto Ryo, Izumi Masayuki, Kajihara Yasuhiro
TETRAHEDRON LETTERS   56(47) 6565-6568   Nov 2015   [Refereed]
Kajihara Y, Nishigaki S, Hanzawa D, Nakanishi G, Okamoto R, Yamamoto N
Chemistry (Weinheim an der Bergstrasse, Germany)   17(27) 7645-7655   Jun 2011   [Refereed]
Okamoto R, Morooka K, Kajihara Y
Angewandte Chemie (International ed. in English)   51(1) 191-196   Jan 2012   [Refereed]
Murakami M, Okamoto R, Izumi M, Kajihara Y
Angewandte Chemie (International ed. in English)   51(15) 3567-3572   Apr 2012   [Refereed]
Orii Ryo, Izumi Masayuki, Kajihara Yasuhiro, Okamoto Ryo
JOURNAL OF CARBOHYDRATE CHEMISTRY   34(9) 560-566   Nov 2015   [Refereed]
Kajihara Y, Yamamoto N, Okamoto R, Hirano K, Murase T
Chemical record (New York, N.Y.)   10(2) 80-100   Apr 2010   [Refereed]
Okamoto Ryo, Izumi Masayuki, Kajihara Yasuhiro
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS   16(3) 191-198   Sep 2010   [Refereed]
Kajihara Yasuhiro, Izumi Masayuki, Hirano Kiriko, Murase Takefumi, Macmillan Derek, Okamoto Ryo
ISRAEL JOURNAL OF CHEMISTRY   51(8-9) 917-929   Nov 2011   [Refereed]
Nagahara N, Matsumura T, Okamoto R, Kajihara Y
Current medicinal chemistry   16(34) 4490-4501   2009   [Refereed]
Okamoto Ryo, Kajihara Yasuhiro
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY   20(114) 203-217   Sep 2008   [Refereed]
Okamoto R, Souma S, Kajihara Y
The Journal of organic chemistry   73(9) 3460-3466   May 2008   [Refereed]
Okamoto Ryo, Kajihara Yasuhiro
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN   66(9) 893-905   Sep 2008   [Refereed]
Yamamoto N, Tanabe Y, Okamoto R, Dawson PE, Kajihara Y
Journal of the American Chemical Society   130(2) 501-510   Jan 2008   [Refereed]
Okamoto R, Kajihara Y
Angewandte Chemie (International ed. in English)   47(29) 5402-5406   2008   [Refereed]
Kajihara Y, Kamitani T, Sato R, Kamei N, Miyazaki T, Okamoto R, Sakakibara T, Tsuji T, Yamamoto T
Carbohydrate research   342(12-13) 1680-1688   Sep 2007   [Refereed]

Misc

 
Amazaki Y, Nguyen HM, Okamoto R, Maki Y, Kajihara Y
Advances in experimental medicine and biology   1104 1-19   Jan 2018   [Refereed]
© Springer Nature Singapore Pte Ltd. 2018. This chapter describes the folding of synthetic homogeneous glycosylpolypeptides into glycoproteins depending on the position and number of glycosylation sites and oligosaccharide structures. To evaluate ...
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY   31(181) SE87-SE88   Jul 2019   [Refereed]
© 2019 FCCA (Forum: Carbohydrates Coming of Age). Recent advances in total chemical synthesis of proteins enable us to prepare complex glycoproteins. Herein, the total chemical synthesis of antifreeze glycoprotein, which is a mucin type O-glycopro...
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY   27(156) E13-J14   Jul 2015   [Refereed]
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY   27(153) 31-32   Jan 2015   [Refereed]
Kajihara Y, Okamoto R, Yamamoto N, Izumi M
Methods in enzymology   478 503-519   Jan 2010   [Refereed]
Oligosaccharides in protein play important roles in several biological events. In order to investigate the functions of oligosaccharides of protein, glycoproteins having homogeneous oligosaccharides should be prepared. For this purpose, preparatio...

Conference Activities & Talks

 
Chemical synthesis of homogeneous antifreeze glycoprotein having uniform GalNAc modification and its antifreeze activity
Okamoto Ryo, Orii Ryo, Izumi Masayuki, Fukami Daichi, Tsuda Sakae, Kajihara Yasuhiro
PROTEIN SCIENCE   Oct 2016   
Chemical synthesis of misfolded glycoproteins as substrates of folding sensor enzyme UGGT
Izumi Masayuki, Kuruma Rie, Okamoto Ryo, Seko Akira, Ito Yukishige, Kajihara Yasuhiro
GLYCOBIOLOGY   Nov 2014   
Biological activities of the homogeneous glycosylated chemokines CCL1 and Ser-CCL1 prepared by total chemical synthesis
Okamoto Ryo, Mandal Kalyanswer, Ling Morris, Luster Andrew, Sawaya Michael, Yeates Todd, Kajihara Yasuhiro, Kent Stephen
GLYCOBIOLOGY   Nov 2014   
Synthetic Study of Erythropoietin Having High Mannose-type Oligosaccharide by Chemical Methodology
Kiuchi Tatsuto, Okamoto Ryo, Izumi Masayuki, Seko Akira, Ito Yukishige, Kajihara Yasuhiro
GLYCOBIOLOGY   Nov 2014   
Total Chemical Synthesis of a Glycosyl Chemokine: Ser-CCL1 and Structural Analysis by Quasi-Racemate X-ray Crystallography
Okamoto Ryo, Mandal Kalyaneswar, Sawaya Michael, Kajihara Yasuhiro, Yeates Todd O., Kent Stephen B. H.
BIOPOLYMERS   2011   

Research Grants & Projects

 
Development of the new convergent one-pot peptide ligations for the synthesis of glycoproteins and crystallography
JSPS: Grants-in-Aid for Scientific Research
Project Year: Apr 2016 - Mar 2019    Investigator(s): Ryo Okamoto
Development of a high-speed peptide synthesis in aqueous solution by using guanidides and thioesters
JSPS: Grants-in-Aid for Scientific Research
Project Year: Apr 2014 - Mar 2016    Investigator(s): Ryo Okamoto
X-ray crystallography of glycoproteins prepared by total chemical synthesis
JSPS: Grants-in-Aid for Scientific Research
Project Year: Apr 2012 - Mar 2014    Investigator(s): Ryo Okamoto