Ryo Okamoto Last updated: Nov 11, 2019 at 16:31
Name
Ryo Okamoto Affiliation
Osaka University Section
Graduate School of ScienceDepartment of Chemistry
Academic & Professional Experience
Jul 2017
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Today
Associate Professor, Department of Chemistry, Graduate School of Science, Osaka University
Sep 2009
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Jun 2017
Assistant Professor, Department of Chemistry, Graduate of School, Osaka University
Aug 2009
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Aug 2010
Postdoctoral Fellow for Research Abroad, JSPS, The University of Chicago
Apr 2009
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Jul 2009
Specially Appointed Researcher, Department of Chemistry, Graduate School of Science, Osaka Universiity
Education
Apr 2006
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Mar 2009
Yokoham City University
Apr 2004
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Mar 2006
Yokohama City University
Apr 2000
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Mar 2004
School of Science, Yokohama City University
Committee Memberships
2018
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Today
International Journal of Peptide Research and Therapeutics Editorial board
Awards & Honors
2015
Incentive Award of Japanese Society of Carbohydrate Research, Japanese Society of Carbohydrate Research
2012
Chemical Society of Japan Presentation Award 2012, Chemical Society of Japan
Published Papers
Okamoto R, Haraguchi T, Nomura K, Maki Y, Izumi M, Kajihara Y
Biochemistry 58(12) 1672-1678 Mar 2019 [Refereed]
Chandrashekar C, Okamoto R, Izumi M, Kajihara Y
Chemistry (Weinheim an der Bergstrasse, Germany) 25(43) 10197-10203 Aug 2019 [Refereed]
Okamoto R, Ono E, Izumi M, Kajihara Y
Frontiers in chemistry 7 173 Mar 2019 [Refereed]
Ryo Okamoto, Kota Nomura, Yuta Maki, Yasuhiro Kajihara
Chemistry Letters 48 1391-1393 Jan 2019
© 2019 The Chemical Society of Japan | 1391 Enzymes and ribosomes accurately form peptide bonds without protecting groups in vivo. Inspired by biological chemistries, we have been exploring a chemoselective reaction for peptide bond formation. In ...
Kiuchi T, Izumi M, Mukogawa Y, Shimada A, Okamoto R, Seko A, Sakono M, Takeda Y, Ito Y, Kajihara Y
Journal of the American Chemical Society 140(50) 17499-17507 Dec 2018 [Refereed]
Maki Y, Mima T, Okamoto R, Izumi M, Kajihara Y
The Journal of organic chemistry 83(1) 443-451 Jan 2018 [Refereed]
Izumi M, Kuruma R, Okamoto R, Seko A, Ito Y, Kajihara Y
Journal of the American Chemical Society 139(33) 11421-11426 Aug 2017 [Refereed]
Orii R, Sakamoto N, Fukami D, Tsuda S, Izumi M, Kajihara Y, Okamoto R
Chemistry (Weinheim an der Bergstrasse, Germany) 23(39) 9253-9257 Jul 2017 [Refereed]
Minh Hien N, Izumi M, Sato H, Okamoto R, Kajihara Y
Chemistry (Weinheim an der Bergstrasse, Germany) 23(27) 6579-6585 May 2017 [Refereed]
Izumi M, Komaki S, Okamoto R, Seko A, Takeda Y, Ito Y, Kajihara Y
Organic & biomolecular chemistry 14(25) 6088-6094 Jul 2016 [Refereed]
Izumi M, Oka Y, Okamoto R, Seko A, Takeda Y, Ito Y, Kajihara Y
Angewandte Chemie (International ed. in English) 55(12) 3968-3971 Mar 2016 [Refereed]
Okamoto R, Isoe M, Izumi M, Kajihara Y
Journal of peptide science : an official publication of the European Peptide Society 22(5) 343-351 May 2016 [Refereed]
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 29(165) E1-E10 Jan 2017 [Refereed]
Maki Y, Okamoto R, Izumi M, Murase T, Kajihara Y
Journal of the American Chemical Society 138(10) 3461-3468 Mar 2016 [Refereed]
Murakami M, Kiuchi T, Nishihara M, Tezuka K, Okamoto R, Izumi M, Kajihara Y
Science advances 2(1) e1500678 Jan 2016 [Refereed]
Kajihara Y, Kanemitsu Y, Nishihara M, Okamoto R, Izumi M
Journal of peptide science : an official publication of the European Peptide Society 20(12) 958-963 Dec 2014 [Refereed]
Okamoto R, Mandal K, Ling M, Luster AD, Kajihara Y, Kent SB
Angewandte Chemie (International ed. in English) 53(20) 5188-5193 May 2014 [Refereed]
Okamoto R, Mandal K, Sawaya MR, Kajihara Y, Yeates TO, Kent SB
Angewandte Chemie (International ed. in English) 53(20) 5194-5198 May 2014 [Refereed]
Okamoto R, Kimura M, Ishimizu T, Izumi M, Kajihara Y
Chemistry (Weinheim an der Bergstrasse, Germany) 20(33) 10425-10430 Aug 2014 [Refereed]
Izumi M, Otsuki A, Nishihara M, Okamoto R, Kajihara Y
Chembiochem : a European journal of chemical biology 15(17) 2503-2507 Nov 2014 [Refereed]
Izumi M, Murakami M, Okamoto R, Kajihara Y
Journal of peptide science : an official publication of the European Peptide Society 20(2) 98-101 Feb 2014 [Refereed]
Okamoto R, Izumi M, Kajihara Y
Current opinion in chemical biology 22 92-99 Oct 2014 [Refereed]
Kajihara Y, Tanabe Y, Sasaoka S, Okamoto R
Chemistry (Weinheim an der Bergstrasse, Germany) 18(19) 5944-5953 May 2012 [Refereed]
Morishita Yasuhito, Kaino Tomoka, Okamoto Ryo, Izumi Masayuki, Kajihara Yasuhiro
TETRAHEDRON LETTERS 56(47) 6565-6568 Nov 2015 [Refereed]
Kajihara Y, Nishigaki S, Hanzawa D, Nakanishi G, Okamoto R, Yamamoto N
Chemistry (Weinheim an der Bergstrasse, Germany) 17(27) 7645-7655 Jun 2011 [Refereed]
Okamoto R, Morooka K, Kajihara Y
Angewandte Chemie (International ed. in English) 51(1) 191-196 Jan 2012 [Refereed]
Murakami M, Okamoto R, Izumi M, Kajihara Y
Angewandte Chemie (International ed. in English) 51(15) 3567-3572 Apr 2012 [Refereed]
Orii Ryo, Izumi Masayuki, Kajihara Yasuhiro, Okamoto Ryo
JOURNAL OF CARBOHYDRATE CHEMISTRY 34(9) 560-566 Nov 2015 [Refereed]
Kajihara Y, Yamamoto N, Okamoto R, Hirano K, Murase T
Chemical record (New York, N.Y.) 10(2) 80-100 Apr 2010 [Refereed]
Okamoto R, Souma S, Kajihara Y
The Journal of organic chemistry 74(6) 2494-2501 Mar 2009 [Refereed]
Okamoto Ryo, Izumi Masayuki, Kajihara Yasuhiro
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 16(3) 191-198 Sep 2010 [Refereed]
Kajihara Yasuhiro, Izumi Masayuki, Hirano Kiriko, Murase Takefumi, Macmillan Derek, Okamoto Ryo
ISRAEL JOURNAL OF CHEMISTRY 51(8-9) 917-929 Nov 2011 [Refereed]
Nagahara N, Matsumura T, Okamoto R, Kajihara Y
Current medicinal chemistry 16(34) 4490-4501 2009 [Refereed]
Okamoto Ryo, Kajihara Yasuhiro
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 20(114) 203-217 Sep 2008 [Refereed]
Okamoto R, Souma S, Kajihara Y
The Journal of organic chemistry 73(9) 3460-3466 May 2008 [Refereed]
Okamoto Ryo, Kajihara Yasuhiro
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 66(9) 893-905 Sep 2008 [Refereed]
Yamamoto N, Tanabe Y, Okamoto R, Dawson PE, Kajihara Y
Journal of the American Chemical Society 130(2) 501-510 Jan 2008 [Refereed]
Okamoto R, Kajihara Y
Angewandte Chemie (International ed. in English) 47(29) 5402-5406 2008 [Refereed]
Kajihara Y, Kamitani T, Sato R, Kamei N, Miyazaki T, Okamoto R, Sakakibara T, Tsuji T, Yamamoto T
Carbohydrate research 342(12-13) 1680-1688 Sep 2007 [Refereed]
Misc
Amazaki Y, Nguyen HM, Okamoto R, Maki Y, Kajihara Y
Advances in experimental medicine and biology 1104 1-19 Jan 2018 [Refereed]
© Springer Nature Singapore Pte Ltd. 2018. This chapter describes the folding of synthetic homogeneous glycosylpolypeptides into glycoproteins depending on the position and number of glycosylation sites and oligosaccharide structures. To evaluate ...
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 31(181) SE87-SE88 Jul 2019 [Refereed]
© 2019 FCCA (Forum: Carbohydrates Coming of Age). Recent advances in total chemical synthesis of proteins enable us to prepare complex glycoproteins. Herein, the total chemical synthesis of antifreeze glycoprotein, which is a mucin type O-glycopro...
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 27(156) E13-J14 Jul 2015 [Refereed]
Okamoto Ryo
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 27(153) 31-32 Jan 2015 [Refereed]
Kajihara Y, Okamoto R, Yamamoto N, Izumi M
Methods in enzymology 478 503-519 Jan 2010 [Refereed]
Oligosaccharides in protein play important roles in several biological events. In order to investigate the functions of oligosaccharides of protein, glycoproteins having homogeneous oligosaccharides should be prepared. For this purpose, preparatio...
Conference Activities & Talks
Chemical synthesis of homogeneous antifreeze glycoprotein having uniform GalNAc modification and its antifreeze activity
Okamoto Ryo, Orii Ryo, Izumi Masayuki, Fukami Daichi, Tsuda Sakae, Kajihara Yasuhiro
PROTEIN SCIENCE Oct 2016
Chemical synthesis of misfolded glycoproteins as substrates of folding sensor enzyme UGGT
Izumi Masayuki, Kuruma Rie, Okamoto Ryo, Seko Akira, Ito Yukishige, Kajihara Yasuhiro
GLYCOBIOLOGY Nov 2014
Biological activities of the homogeneous glycosylated chemokines CCL1 and Ser-CCL1 prepared by total chemical synthesis
Okamoto Ryo, Mandal Kalyanswer, Ling Morris, Luster Andrew, Sawaya Michael, Yeates Todd, Kajihara Yasuhiro, Kent Stephen
GLYCOBIOLOGY Nov 2014
Synthetic Study of Erythropoietin Having High Mannose-type Oligosaccharide by Chemical Methodology
Kiuchi Tatsuto, Okamoto Ryo, Izumi Masayuki, Seko Akira, Ito Yukishige, Kajihara Yasuhiro
GLYCOBIOLOGY Nov 2014
Total Chemical Synthesis of a Glycosyl Chemokine: Ser-CCL1 and Structural Analysis by Quasi-Racemate X-ray Crystallography
Okamoto Ryo, Mandal Kalyaneswar, Sawaya Michael, Kajihara Yasuhiro, Yeates Todd O., Kent Stephen B. H.
BIOPOLYMERS 2011
Research Grants & Projects
Development of the new convergent one-pot peptide ligations for the synthesis of glycoproteins and crystallography
JSPS: Grants-in-Aid for Scientific Research
Project Year: Apr 2016 - Mar 2019 Investigator(s): Ryo Okamoto
Development of a high-speed peptide synthesis in aqueous solution by using guanidides and thioesters
JSPS: Grants-in-Aid for Scientific Research
Project Year: Apr 2014 - Mar 2016 Investigator(s): Ryo Okamoto
X-ray crystallography of glycoproteins prepared by total chemical synthesis
JSPS: Grants-in-Aid for Scientific Research
Project Year: Apr 2012 - Mar 2014 Investigator(s): Ryo Okamoto