Seiichi Ohta

Profile Information

Affiliation: 准教授, 大学院工学系研究科総合研究機構, 東京大学

Researcher number: 40723284
J-GLOBAL ID: 202001007643824710
researchmap Member ID: R000009103

Research Interests

Research History

Dec, 2020 - Present

JSTさきがけ研究員(兼任)
Apr, 2020 - Present

Associate Professor, The Graduate School of Engineering Institute of Engineering Innovation, The University of Tokyo
Apr, 2020 - Present

Associate Professor, The Graduate School of Engineering Department of Chemical System Engineering, The University of Tokyo
Apr, 2020 - Present

Associate Professor, The Graduate School of Engineering Department of Bioengineering, The University of Tokyo
Apr, 2016 - Mar, 2020

Assistant Professor, Graduate School of Medicine Center for Disease Biology and Integrative Medicine, The University of Tokyo
Apr, 2013 - Mar, 2016

JSPS post doctodar fellow (PD), Graduate School of Medicine Center for Disease Biology and Integrative Medicine, The University of Tokyo
Mar, 2014 - Aug, 2015

JSPS post doctodar fellow (PD), Institute of Biomaterials & Biomedical Engineering, Unoversity of Toronto

Education

Apr, 2010 - Mar, 2013

Department of Chemical System Engineering, The Graduate School of Engineering, The University of Tokyo
Apr, 2008 - Mar, 2010

Department of Chemical System Engineering, The Graduate School of Engineering, The University of Tokyo
Apr, 2004 - Mar, 2008

Department of Chemical System Engineering, The Faculty of Engineering, The University of Tokyo

Awards

Dec, 2020

令和２年度東京大学卓越研究員

太田誠一
Mar, 2019

研究奨励賞(玉置明善記念賞), 化学工学会
Mar, 2013

工学系研究科長賞, 東京大学大学院
Sep, 2010

Young Researcher Award, AsiaNano 2010
2010

若手研究者大会長賞, 第32回日本バイオマテリアル学会大会

Papers

Centrifugal Field-Flow Fractionation Enables Detection of Slight Aggregation of Nanoparticles That Impacts Their Biomedical Applications

Hiroki Tsuchiya, Noriko Nakamura, Seiichi Ohta

Analytical Chemistry, Apr, 2024 Peer-reviewedLast authorCorresponding author
Precise control methods of the physicochemical properties of nanoparticles for personalized medicine

Noriko Nakamura, Seiichi Ohta

Current Opinion in Biotechnology, Apr, 2024 Peer-reviewedInvitedLast authorCorresponding author
DNA‐Mediated, On‐Membrane Sequential Assembly of Conjugated Polymer Nanoparticles for Sensitive Detection of Cell Surface Markers

Yuki Maeda, Noriko Nakamura, Seiichi Ohta

Advanced Functional Materials, Jan 20, 2024 Last authorCorresponding author
Injectable, shear-thinning, photocrosslinkable, and tissue-adhesive hydrogels composed of diazirine-modified hyaluronan and dendritic polyethyleneimine.

Arvind K Singh Chandel, Athira Sreedevi Madhavikutty, Saki Okada, Zhang Qiming, Natsuko F Inagaki, Seiichi Ohta, Taichi Ito

Biomaterials science, Jan 15, 2024
Development of stealth nanoparticles coated with poly(2‐methoxyethyl vinyl ether) as an alternative to poly(ethylene glycol)

Kento Fujiura, Mitsuru Naito, Yukiko Tanaka, Masaru Tanaka, Yurie Nakanishi, Hirotaka Ejima, Lumi Negishi, Tomoya Kujirai, Hitoshi Kurumizaka, Seiichi Ohta …

Journal of Applied Polymer Science, 141(11), Dec 14, 2023
A Systems Evaluation Model for the Development of Companion Diagnostics and Associated Molecularly Targeted Therapies

Kozue Okamura, Hiroki Tsuchiya, Risa Hamada, Yusuke Hayashi, Sara Badr, Seiichi Ohta, Hirokazu Sugiyama

Journal of Pharmaceutical Innovation, 18(4) 2265-2276, Dec 11, 2023
Prevention of esophageal stenosis via in situ cross-linkable alginate/gelatin powder in a new submucosal exfoliation model in rats.

Qi Pan, Yosuke Tsuji, Athira Sreedevi Madhavikutty, Seiichi Ohta, Ayano Fujisawa, Natsuko F Inagaki, Mitsuhiro Fujishiro, Taichi Ito

Biomaterials science, 11(20) 6781-6789, Oct 10, 2023
Progress of Endogenous and Exogenous Nanoparticles for Cancer Therapy and Diagnostics

Hideaki Fujita, Seiichi Ohta, Noriko Nakamura, Masaharu Somiya, Masanobu Horie

Genes, 14(2) 259-259, Jan 19, 2023
Selecting optimum miRNA panel for miRNA signature-based companion diagnostic model to predict the response of R-CHOP treatment in diffuse large B-cell lymphoma

Noriko Nakamura, Risa Hamada, Hiromasa Kaneko, Seiichi Ohta

Journal of Bioscience and Bioengineering, Jan, 2023 Last authorCorresponding author
pH responsive cationic guar gum-borate self-healing hydrogels for muco-adhesion.

Athira Sreedevi Madhavikutty, Arvind K Singh Chandel, Ching-Cheng Tsai, Natsuko F Inagaki, Seiichi Ohta, Taichi Ito

Science and technology of advanced materials, 24(1) 2175586-2175586, 2023
Development of a Potassium-Ion-Responsive Star Copolymer with Controlled Aggregation/Dispersion Transition

Noriko Nakamura, Seiichi Ohta, Mariko Yamada, Yukimitsu Suzuki, Natsuko F. Inagaki, Takeo Yamaguchi, Taichi Ito

ACS Omega, Dec 23, 2022
Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence

Masashi Okawa, Aki Tanabe, Seiichi Ohta, Satoru Nagatoishi, Kouhei Tsumoto, Taichi Ito

Communications Materials, Oct 30, 2022 Peer-reviewed
Recent advances in animal cell technologies for industrial and medical applications.

Masanobu Horie, Noriko Yamano-Adachi, Yoshinori Kawabe, Hidenori Kaneoka, Hideaki Fujita, Eiji Nagamori, Ryosuke Iwai, Yasushi Sato, Kei Kanie, Seiichi Ohta …

Journal of bioscience and bioengineering, 133(6) 509-514, Jun, 2022
Balance of antiperitoneal adhesion, hemostasis, and operability of compressed bilayer ultrapure alginate sponges.

Arvind K Singh Chandel, Seiichi Ohta, Machiko Taniguchi, Hiromi Yoshida, Daichi Tanaka, Kiyohiko Omichi, Atsushi Shimizu, Mitsuko Isaji, Kiyoshi Hasegawa, Taichi Ito

Biomaterials advances, 137 212825-212825, Jun, 2022
Silver-loaded carboxymethyl cellulose nonwoven sheet with controlled counterions for infected wound healing

Seiichi Ohta, Kento Mitsuhashi, Arvind K. Singh Chandel, Pan Qi, Noriko Nakamura, Akiko Nakamichi, Hiromi Yoshida, Gento Yamaguchi, Yuichi Hara, Ryo Sasaki …

Carbohydrate Polymers, 286 119289-119289, Jun, 2022
Cisplatin-Chelated Iminodiacetic Acid-Conjugated Hyaluronic Acid Nanogels for the Treatment of Malignant Pleural Mesothelioma in Mice.

Yuki Amano, Kazuma L Sakura, Seiichi Ohta, Taichi Ito

Molecular pharmaceutics, 19(3) 853-861, Mar 7, 2022
Analysis of model drug permeation through highly crosslinked and biodegradable polyethylene glycol membranes

Kento Mitsuhashi, Seiichi Ohta, Taichi Ito

Journal of Membrane Science, 645, Mar 5, 2022
Injectable bottlebrush triblock copolymer hydrogel crosslinked with ferric ions

Yoshiyuki Nakagawa, Yuichiro Oki, Xiao Da, Arvind K. Singh Chandel, Seiichi Ohta, Taichi Ito

Polymer, 240, Feb 1, 2022
Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe

Noriko Nakamura, Nobuaki Tanaka, Seiichi Ohta

RSC Advances, 12(19) 11606-11611, 2022 Last authorCorresponding author
Intraperitoneal Administration of a Cisplatin-Loaded Nanogel through a Hybrid System Containing an Alginic Acid-Based Nanogel and an In Situ Cross-Linkable Hydrogel for Peritoneal Dissemination of Ovarian Cancer

Kohei Yamaguchi, Osamu Hiraike, Haruna Iwaki, Kazuki Matsumiya, Noriko Nakamura, Kenbun Sone, Seiichi Ohta, Yutaka Osuga, Taichi Ito

Molecular Pharmaceutics, Oct 18, 2021

Misc.

機能化リンクモジュールの設計とECM模倣ハイドロゲルの開発

大川将志, 田部亜希, 太田誠一, 長門石曉, 津本浩平, 津本浩平, 伊藤大知, 伊藤大知

日本再生医療学会総会(Web), 21st, 2022
Design of genetically engineered Link module and development of ECM mimetic hydrogel

大川将志, 田部亜季, 太田誠一, 長門石曉, 津本浩平, 津本浩平, 伊藤大知, 伊藤大知

日本生物工学会大会講演要旨集, 73rd, 2021
Three-pore modelを用いた腹膜播種への薬物送達モデルの構築

松田昂大, 太田誠一, 伊藤大知, 伊藤大知

膜シンポジウム(CD-ROM), (33), 2021
腹膜播種治療のための腹腔内薬物徐放システムの数理モデルを用いた設計

松田昂大, 太田誠一, 伊藤大知, 伊藤大知

化学工学会秋季大会研究発表講演要旨集(CD-ROM), 52nd, 2021
鎖長の異なるポリリン酸修飾ヒアルロン酸の免疫応答及び止血効果への影響

大川将志, 迫田龍, 太田誠一, 矢冨裕, 矢冨裕, 伊藤大知, 伊藤大知

日本血栓止血学会誌, 32(2), 2021
薬物透過制御のための生分解性高架橋密度PEG膜の開発

三橋健斗, 太田誠一, 伊藤大知, 伊藤大知

化学工学会年会研究発表講演要旨集(CD-ROM), 86th, 2021
卵巣癌腹膜播種治療に向けたシスプラチン担持アルギン酸ナノゲル封入ハイドロゲルの開発

山口広平, 平池修, 岩城晴奈, 曾根献文, 太田誠一, 大須賀穣, 伊藤大知

日本DDS学会学術集会プログラム予稿集, 37th, 2021
薬物透過量制御のための生分解性PEG膜の開発

三橋健斗, 太田誠一, 伊藤大知

日本DDS学会学術集会プログラム予稿集, 37th, 2021
Designing of drug sustained-release hydrogel for peritoneal dissemination by using mathematical model.

松田昂大, 太田誠一, 伊藤大知, 伊藤大知

日本膜学会年会講演要旨集(CD-ROM), 43rd, 2021
Development of genetically engineered Link module and fabrication of ECM analogue

大川将志, 田部亜季, 太田誠一, 長門石曉, 津本浩平, 津本浩平, 伊藤大知, 伊藤大知

日本膜学会年会講演要旨集(CD-ROM), 43rd, 2021
Development of hydrogel for sustained release of protease inhibitor to prevent pancreatic fistula.

三橋健斗, 太田誠一, 伊藤大知, 伊藤大知

日本膜学会年会講演要旨集, 42nd, 2020
アルギン酸カプセル中における膵β細胞からのインスリン分泌振動のカオス解析

大木悠一朗, 太田誠一, 伊藤大知, 伊藤大知

膜シンポジウム, (32 (CD-ROM)), 2020
物質拡散制御のための生分解性高架橋密度PEG膜の開発

三橋健斗, 戚蟠, 太田誠一, 伊藤大知, 伊藤大知

膜シンポジウム, (32 (CD-ROM)), 2020
内視鏡的粘膜下層剥離術後の食道狭窄防止するためのin situ架橋パウダー材料の開発

戚蟠, 太田誠一, 藤澤彩乃, 辻陽介, 藤城光弘, 伊藤大知

日本再生医療学会総会(Web), 19th, 2020
アルツハイマー病治療を目指したアミロイドβ標的金ナノ粒子の開発

太田誠一, 小野村知之, 伊藤大知, 伊藤大知

化学工学会年会研究発表講演要旨集(CD-ROM), 85th, 2020
Insulin oscillation secreted from pancreatic β cells encapsulated in alginate capsule.

大木悠一朗, 太田誠一, 伊藤大知, 伊藤大知

日本膜学会年会講演要旨集, 42nd, 2020
インクジェットプリンティングを用いたシスプラチン徐放シートの開発

岩城晴奈, CHANDEL Arvind Singh, 戚蟠, 太田誠一, 伊藤大知, 伊藤大知

膜シンポジウム, (32 (CD-ROM)), 2020
ハイドロゲルカプセル培養下での液性因子BMP-2模倣ペプチドのin situ導入による細胞分化スイッチング

大木悠一朗, 太田誠一, 大庭伸介, 伊藤大知, 伊藤大知

日本再生医療学会総会(Web), 19th, 2020
生体内分子送達技術とその応用-ドラッグデリバリーシステムとその周辺技術-細胞外マトリックス分子に着目したドラッグデリバリーシステム

太田誠一, 伊藤大知

化学工学, 83(7), 2019
鎖長の異なる低分子量ポリリン酸のin vitroおよびin vivoでの生体適合性評価

大川将志, 太田誠一, 伊藤大知

化学工学会年会研究発表講演要旨集(CD-ROM), 84th, 2019

Research Projects

Development of rapid manufacturing support system for anti-pandemic drugs

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2025
可逆的ナノ粒子集積を用いたタンパク質の超マルチカラー・高感度イメージング基盤

科学研究費助成事業基盤研究(B), 基盤研究(B), 日本学術振興会, Apr, 2021 - Mar, 2024

太田誠一
微量脳内分子の完全網羅解析を実現する極限検出システムの開発

科学研究費助成事業学術変革領域研究(B), 学術変革領域研究(B), 日本学術振興会, Aug, 2021 - Mar, 2024

川井隆之、太田誠一
塩基配列からナノ粒子配列への自在変換が拓く生命情報検出

戦略的創造研究推進事業（さきがけ）「原子・分子の自在配列と特性・機能」領域, 国立研究開発法人科学技術振興機構, Dec, 2020 - Mar, 2024

太田誠一
マルチスケール反応拡散モデル構築による薬物送達のための腹膜播種巣の統合的理解

科学研究費助成事業挑戦的研究(萌芽), 挑戦的研究(萌芽), 日本学術振興会, Jul, 2020 - Mar, 2022

伊藤大知, 北山丈二, 太田誠一
多発性骨髄腫の免疫抑制環境を排除しながら抗腫瘍免疫応答を誘導できる新規ナノ粒子の開発

革新的がん医療実用化研究事業, 国立研究開発法人日本医療研究開発機構, Oct, 2019 - Mar, 2022

籠谷勇紀、太田誠一
ナノ粒子への異物認識を巧みに利用/制御した新規アルツハイマー病治療システムの開発

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2019 - Mar, 2021

太田誠一
膵液応答架橋性を有する新規膵液瘻防止材料の開発

科学研究費助成事業基盤研究(B), 基盤研究(B), 日本学術振興会, Apr, 2017 - Mar, 2020

伊藤大知, 酒井康行, 長谷川潔, 浦野泰照, 太田誠一
再生内分泌組織の迅速応答を可能とする血流導入型ユニバーサル移植プラットフォーム

科学研究費助成事業基盤研究(A), 基盤研究(A), 日本学術振興会, Apr, 2016 - Mar, 2020

酒井康行, 國土典宏, 稲垣奈都子, 太田誠一, 宮島篤, 伊藤大知, 稲垣冬樹, 田中稔
Development of novel in situ crosslinked hydrogel using lectins

Grants-in-Aid for Scientific Research Challenging Research (Exploratory), Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jun, 2017 - Mar, 2019

Ito Taichi
Development of "large but small" caged carriers using nanoparticles as building blocks

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Ohta Seiichi
Development of new treatments of peritoneal disorders using multi-layered, in situ cross-likable hydrogels

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Ito Taichi, KITAYAMA Joji, KOKUDO Norihiro
Evaluation of tumor penetration ability of nanoparticles using 3D cell culture system toward particle design optimization

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016

Ohta Seiichi
Development of novel anti-adhesion materials using an animal posthepatectomy adhesion model

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2016

Shimizu Atsushi, NISHIYAMA Toru, ITO Taichi, Ohta Seiichi, KOKUDO Norihiro, HASEGAWA Kiyoshi
シリコン量子ドットと腹腔鏡を用いた腹膜播種の新規蛍光診断／治療法の一体化開発

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, Apr, 2013 - Mar, 2016

太田誠一
分子、粒子、細胞の配向構造形成メカニズム

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 2010 - 2012

太田誠一

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