肥後修一朗 (Shuichiro Higo) - 論文

Heart‐on‐a‐Miniscope: A Miniaturized Solution for Electrophysiological Drug Screening in Cardiac Organoids

Pouria Tirgar, Abigail Vikstrom, José Miguel, Romero Sepúlveda, Luv Kishore Srivastava, Ali Amini, Tomoka Tabata, Shuichiro Higo, Gil Bub, Allen Ehrlicher

Small 2024年12月29日査読有り

Four cardiomyopathy patients with a heterozygous DSG2 p.Arg119Ter variant

Takuya Sumida, Shou Ogawa, Shuichiro Higo, Yuki Kuramoto, Ryo Eto, Yoshihiko Ikeda, Congcong Sun, Junjun Li, Li Liu, Tomoka Tabata …

Human Genome Variation 11(1) 2024年12月20日査読有り責任著者

Protein C deficiency with recurrent systemic thrombosis associated with compound heterozygous PROC missense variants

Mikio Shiba, Shuichiro Higo, Yu Morishita, Yasuhiro Ichibori, Yoshihiro Kin, Yasushi Sakata, Yoshiharu Higuchi

American Heart Journal Plus: Cardiology Research and Practice 100496-100496 2024年12月査読有り責任著者

Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment

Junjun Li, Ying Hua, Yuting Liu, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Hayato Miyoshi, Mikio Shiba …

iScience 27(2) 108992-108992 2024年2月査読有り

Gene correction and overexpression of TNNI3 improve impaired relaxation in engineered heart tissue model of pediatric restrictive cardiomyopathy

Moyu Hasegawa, Kenji Miki, Takuji Kawamura, Ikue Takei Sasozaki, Yuki Higashiyama, Masaru Tsuchida, Kunio Kashino, Masaki Taira, Emiko Ito, Maki Takeda …

Development, Growth & Differentiation 2024年1月9日査読有り

SARS-CoV-2 spike receptor-binding domain is internalized and promotes protein ISGylation in human induced pluripotent stem cell-derived cardiomyocytes

Shota Okuno, Shuichiro Higo, Takumi Kondo, Mikio Shiba, Satoshi Kameda, Hiroyuki Inoue, Tomoka Tabata, Shou Ogawa, Yu Morishita, Congcong Sun …

Scientific Reports 13(1) 2023年12月4日査読有り責任著者

Tenascin-C as a Potential Marker for Immunohistopathology of Doxorubicin-Induced Cardiomyopathy

Tatsuya Nishikawa, Mikio Shiba, Yoshihiko Ikeda, Keiko Ohta-Ogo, Takumi Kondo, Tomoka Tabata, Toru Oka, Wataru Shioyama, Hironori Yamamoto, Taku Yasui …

European Heart Journal Open 2023年10月9日査読有り

Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation

Hideaki Fujita, Junichi Kaneshiro, Maki Takeda, Kensuke Sasaki, Rikako Yamamoto, Daiki Umetsu, Erina Kuranaga, Shuichiro Higo, Takumi Kondo, Yoshihiro Asano …

Life Sci Alliance 6(7) e202302070-e202302070 2023年5月26日査読有り

Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin

Tatsuro Hitsumoto, Osamu Tsukamoto, Ken Matsuoka, Junjun Li, Li Liu, Yuki Kuramoto, Shuichiro Higo, Shou Ogawa, Noboru Fujino, Shohei Yoshida …

Circulation 147(25) 1902-1918 2023年5月2日査読有り

Disease modeling of desmosome-related cardiomyopathy using induced pluripotent stem cell-derived cardiomyocytes

Shuichiro Higo

World Journal of Stem Cells 15(3) 71-82 2023年3月26日査読有り招待有り筆頭著者責任著者

Modeling Reduced Contractility and Stiffness Using iPSC-Derived Cardiomyocytes Generated From Female Becker Muscular Dystrophy Carrier

Satoshi Kameda, Shuichiro Higo, Mikio Shiba, Takumi Kondo, Junjun Li, Li Liu, Tomoka Tabata, Hiroyuki Inoue, Shota Okuno, Shou Ogawa …

JACC: Basic to Translational Science 2023年2月査読有り責任著者

End-stage Hypertrophic Cardiomyopathy with Advanced Heart Failure in Patients Carrying MYH7 R453 Variants: A Case Series

Susumu Naito, Shuichiro Higo, Satoshi Kameda, Shou Ogawa, Tomoka Tabata, Yasuhiro Akazawa, Daisuke Nakamura, Kei Nakamoto, Fusako Sera, Yuki Kuramoto …

Internal Medicine 2023年査読有り責任著者

Multiplexed measurement of cell type-specific calcium kinetics using high-content image analysis combined with targeted gene disruption

Tomoka Tabata, Yuki Masumura, Shuichiro Higo, Suzuka Kunimatsu, Satoshi Kameda, Hiroyuki Inoue, Shota Okuno, Shou Ogawa, Seiji Takashima, Mikio Watanabe …

Biochemical and Biophysical Research Communications 637 40-49 2022年11月査読有り責任著者

Human-Induced Pluripotent Stem Cell–Derived Cardiomyocyte Model for TNNT2 Δ160E-Induced Cardiomyopathy

Takumi Kondo, Shuichiro Higo, Mikio Shiba, Yasuaki Kohama, Satoshi Kameda, Tomoka Tabata, Hiroyuki Inoue, Shota Okuno, Shou Ogawa, Satoki Nakamura …

Circulation: Genomic and Precision Medicine 15(5) 101161CIRCGEN121003522 2022年7月12日査読有り責任著者

Modeling reduced contractility and impaired desmosome assembly due to plakophilin-2 deficiency using isogenic iPS cell-derived cardiomyocytes

Hiroyuki Inoue, Satoki Nakamura, Shuichiro Higo, Mikio Shiba, Yasuaki Kohama, Takumi Kondo, Satoshi Kameda, Tomoka Tabata, Shota Okuno, Yoshihiko Ikeda …

Stem Cell Reports 17(2) 337-351 2022年1月査読有り責任著者

Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series

Tomoka Tabata, Yuki Kuramoto, Tomohito Ohtani, Hiroshi Miyawaki, Yohei Miyashita, Fusako Sera, Hidetaka Kioka, Shuichiro Higo, Yoshihiro Asano, Shungo Hikoso …

Internal Medicine 61(13) 1987-1993 2022年査読有り

Polycythemia Vera Associated with Pulmonary Hypertension and Diffuse Large B-Cell Lymphoma: A Case Report

Satoshi Kameda, Fusako Sera, Kazuaki Sato, Masako Kurashige, Shuichiro Higo, Tomohito Ohtani, Akihiro Tsuboi, Shungo Hikoso, Eiichi Morii, Osamu Yamaguchi …

American Journal of Case Reports 22 e932956 2021年7月14日査読有り

Homogeneous 2D and 3D alignment of cardiomyocyte in dilated cardiomyopathy revealed by intravital heart imaging

Kiyoshi Masuyama, Tomoaki Higo, Jong-Kook Lee, Ryohei Matsuura, Ian Jones, Chris Bakal, Shuichiro Higo, Sachio Morimoto, Shigeru Miyagawa, Yoshiki Sawa …

Scientific Reports 11(1) 14698-14698 2021年7月査読有り

Phenotypic Recapitulation and Correction of Desmoglein-2-deficient Cardiomyopathy using Human Induced Pluripotent Stem Cell-derived Cardiomyocytes

Mikio Shiba, Shuichiro Higo, Takumi Kondo, Junjun Li, Li Liu, Yoshihiko Ikeda, Yasuaki Kohama, Satoshi Kameda, Tomoka Tabata, Hiroyuki Inoue …

Human Molecular Genetics 30(15) 1384-1397 2021年5月5日査読有り責任著者

Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes

Hideki Yasutake, Jong-Kook Lee, Akihito Hashimoto, Kiyoshi Masuyama, Jun Li, Yuki Kuramoto, Shuichiro Higo, Shungo Hikoso, Kyoko Hidaka, Atsuhiko T. Naito …

Scientific Reports 11(1) 2021年5月査読有り

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