TOMOHIKO SAKUDA - My portal

Profile Information

Affiliation: 助教, 整形外科, 広島大学

Degree: 博士（医学）(Mar, 2020, 広島大学)

Researcher number: 60878289
J-GLOBAL ID: 202001003069750279
researchmap Member ID: R000010758

I specialize in clinical and basic bone and soft tissue tumors at Hiroshima University Orthopedic Surgery. In clinical practice, I am familiar with chemotherapy as well as surgery. Basically, we are conducting research on the treatment of malignant tumors using oncolytic viruses.

Research Interests

Research History

Apr, 2020

Assistant Professor, Department of Orthpaedic Surgery, Hiroshima University
Apr, 2016 - Mar, 2020

clinical staff, Department of Orthopaedic Surgery, Hiroshima University
Apr, 2014 - Mar, 2016

Orthopedic doctor, Saiseikai Kure Hospital
Apr, 2012 - Mar, 2014

Orthopedic doctor, Hiroshima City Hiroshima Citizens Hospital
Apr, 2010 - Mar, 2012

medical intern, Matsuyama Red Cross Hospital

Education

Apr, 2016 - Mar, 2020

Graduate School of Biomedical & Health Sciences, Graduate School of Biomedical & Health Sciences, Hiroshima University
Apr, 2004 - Mar, 2010

Ehime University

Awards

2019

1st winner of poster presentation, Novel near-infrared fluorescence-guided surgery with vesicular stomatitis virus for complete surgical resection of osteosarcomas in mice., 19th Grand Round Musculoskeletal Oncology (Indonesia)

Papers

Synergistic VSV Virotherapy and Carbon Nanotube Photothermal Therapy for Osteosarcoma in Murine Models

Tomohiko Sakuda, Akihiro Oda, Taisuke Furuta, Muhammad Phetrus Johan, Takemasa Sakaguchi, Nobuo Adachi

Anticancer Research, 44(1) 99-105, 2024 Peer-reviewed
Myopericytoma of the patella with local recurrence and patellectomy: A case report

Tomohiko Sakuda, Taisuke Furuta, Nobuo Adachi

International Journal of Surgery Case Reports, 2024 Peer-reviewed
Metastatic patellar bone tumor due to gastric cancer resembling a primary or secondary aneurysmal bone cyst: A case report

Furuta, T., Sakuda, T., Yoshioka, K., Arihiro, K., Adachi, N.

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 108, Jul, 2023 Peer-reviewed
Functional outcome of campanacci grade 3 giant cell tumours of distal radius after resection and reconstruction with ulnar translocation technique: a case series

Johan, Muhammad Phetrus, Sukendar, Anthony Evans, Yurianto, Henry, Singjie, Leonard Christianto, Abidin, Mohammad Asri, Arifin, Jainal, Usman, Muhammad Andry, Sakuda, Tomohiko, Saleh, M. Ruksal

ANNALS OF MEDICINE AND SURGERY, 85(6) 3179-3186, Jun, 2023 Peer-reviewed
Oncolytic Effect of a Recombinant Vesicular Stomatitis Virus Encoding a Tumor-suppressor MicroRNA in an Osteosarcoma Mouse Model

Sakuda, Tomohiko, Kubo, Tadahiko, Johan, Muhammad Phetrus, Furuta, Taisuke, Sakaguchi, Takemasa, Adachi, Nobuo

ANTICANCER RESEARCH, 43(3) 1185-1191, Mar, 2023 Peer-reviewed
Utility of intraoperative magnetic resonance imaging for giant cell tumor of bone after denosumab treatment: a pilot study

Furuta, Taisuke, Kubo, Tadahiko, Sakuda, Tomohiko, Saito, Taiichi, Kurisu, Kaoru, Muragaki, Yoshihiro, Adachi, Nobuo

ACTA RADIOLOGICA, 63(2) 176-181, Feb, 2022 Peer-reviewed
Incomplete Atypical Femoral Fracture Treated by Prophylactic Intramedullary Nail Fixation: A Case Series

Tomohiko Sakuda, Osamu Omoto, Takahiko Hamasaki, Nobukazu Okimoto, Nobuo Adachi

Cureus, 2022 Peer-reviewed
Tuberculosis of the knee masquerading as pigmented villonodular synovitis: Report of two cases

Johan, Muhammad Phetrus, Purnama, Imeldy Prihatni, Nurdin, Iswahyudi, Asy'arie, Ahmad Perdana, Wawolumaja, Arian Fardin Ignatius, Sakuda, Tomohiko

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 88, Nov, 2021 Peer-reviewed
Giant cell tumor of the cervical spine treated by carbon ion radiotherapy A case report

Sakuda, Tomohiko, Furuta, Taisuke, Okimoto, Tomoaki, Adachi, Nobuo

MEDICINE, 100(41), Oct 15, 2021 Peer-reviewed
Extraskeletal Ewing sarcoma attached to the ulnar nerve: A case report

Sakuda, Tomohiko, Furuta, Taisuke, Johan, Muhammad Phetrus, Arihiro, Koji, Adachi, Nobuo

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 80, 2021 Peer-reviewed
Development of an Oncolytic Recombinant Vesicular Stomatitis Virus Encoding a Tumor-suppressor MicroRNA

Tomohiko Sakuda, Tadahiko Kubo, Muhammad Petrus Johan, Taisuke Furuta, Takemasa Sakaguchi, Nobuo Adachi

Anticancer Research, 40(11) 6319-6325, Nov, 2020 Peer-reviewed
Rapidly growing Fibro-osseous pseudotumor of the digit A case report

Tomohiko Sakuda, Tadahiko Kubo, Rikuo Shinomiya, Taisuke Furuta, Nobuo Adachi

Medicine (Baltimore), 99(28), Jul 10, 2020 Peer-reviewed
Granulocyte Colony-Stimulating Factor-Induced Aortitis with Lung Injury, Splenomegaly, and a Rash During Treatment for Recurrent Extraosseous Mucinous Chondrosarcoma

Takahiro Kametani, Yuichiro Otani, Toshikazu Ohigashi, Tadahiko Kubo, Tomohiko Sakuda, Taisuke Furuta, Yayoiko Ito, Yuya Shigenobu, Masaki Kakimoto, Akihiro Kawahara, Yuka Kikuchi, Tomoki Kobayashi, Daisuke Miyamori, Nobusuke Kishikawa, Keishi Kanno, Masanori Ito

Internal Medicine, 60(8) 1311-1315, 2020 Peer-reviewed
Novel Near-Infrared Fluorescence-Guided Surgery With Vesicular Stomatitis Virus for Complete Surgical Resection of Osteosarcomas in Mice.

Tomohiko Sakuda, Tadahiko Kubo, Muhammad Phetrus Jphan, Taisuke Furuta, Takemasa Sakaguchi, Mahito Nakanishi, Mitsuo Ochi, Nobuo Adachi

Journal of Orthopaedic Research, 37(5) 1192-1201, 2019 Peer-reviewed
Coexistence of giant cell tumor of tendon sheath and enchondroma in the middle phalanx of the little finger mimicking a malignant tumor: A case report.

Johan MP, Kubo T, Furuta T, Sakuda T, Adachi N

Oncology Letters, 17(2) 1969-1973, 2019 Peer-reviewed
Conventional 99mTc-(hydroxy) methylene dishosphate remains useful to predict osteosarcoma response to neoadjuvant chemotherapy: Individual patient data and aggregate data meta-analyses.

Kubo T, Furuta T, Sakuda T, Ochi M, Adachi N

Medicine (Baltimore), 97(51), 2018 Peer-reviewed
A meta-analysis supports core needle biopsy by radiologists for better histological diagnosis in soft tissue and bone sarcomas.

Kubo T, Furuta T, Johan MP, Sakuda T, Ochi M, Adachi N

Medicine (Baltimore), 97(29), 2018 Peer-reviewed
Effect of Continuous Compression Stimulation on Pressure-Pain Threshold and Muscle Spasms in Older Adults With Knee Osteoarthritis: A Randomised Trial.

Tanaka R, Umehara T, Kawabata Y, Sakuda T

J Manipulative Physiol Ther, 41(4) 315-322, 2018 Peer-reviewed
Metastatic Tumor Cells Detection and Anti-Metastatic Potential with Vesicular Stomatitis Virus in Immunocompetent Murine Model of Osteosarcoma.

Johan MP, Kubo T, Furuta T, Sakuda T, Sakaguchi T, Nakanishi M, Ochi M, Adachi N

36(9) 2562-2569, 2018 Peer-reviewed

Books and Other Publications

Journal of Joint Surgery

(Role: Joint author)

Oct, 2020
別冊整形外科【整形外科診療における最先端技術】

古田太輔、久保忠彦、作田智彦、斎藤太一、安達伸生 (Role: Joint author)

2019

Presentations

Novel near-infrared fluorescence-guided surgery with vesicular stomatitis virus for complete surgical resection of osteosarcomas in mice

Tomohiko Sakuda, Tadahiko Kubo, Muhammad Petrus Johan, Taisuke Furuta, Mitsuo Ochi, Nobuo Adachi

19th Grand Round Musculoskeletal Oncology (Indonesia), Mar 8, 2019 Invited

Professional Memberships

Research Projects

低酸素下でのみ薬剤を遊離作用可能にしたプロドラッグを用いた骨肉腫治療の開発

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2022 - Mar, 2025

古田太輔, 池田豊, 味八木茂, 作田智彦
Malignant tumor treatment strategy using a combination of oncolytic virus and carbon nanotubes

Grants-in-Aid for Scientific Research, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
Tumor-suppressor microRNA導入組換え腫瘍溶解性ウイルスの抗腫瘍効果

一般財団法人緑風会教育研究奨励賞(若手研究者助成金), 緑風会, Apr, 2019 - Mar, 2020

作田智彦
水疱性口内炎ウイルス(vesicular stomatitis virus; VSV)とカーボンナノチューブを組み合わせた骨肉腫に対する新たな低侵襲治療の開発

令和3(2021)年度科学研究費助成事業(若手研究), 日本学術振興会

作田智彦