2018年
pH stability and antioxidant power of CycloDOPA and its derivatives
Molecules
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- 巻
- 23
- 号
- 8
- 開始ページ
- 1943
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.3390/molecules23081943
© 2018 by the authors. CycloDOPA (leukodopachrome), a well known metabolite of tyrosine, is a precursor of melanine in mammalian organisms and of the pigment betalain in plants. However, the isolation of cycloDOPA from natural sources has not been widely reported. In the present work, the stabilities of cycloDOPA and cycloDOPA methyl ester at various pH levels were studied. Both compounds were stable under acidic conditions. By contrast, both compounds were unstable when the pH was shifted from neutral to basic to form indole derivatives as major products. Based on the pH stability, cycloDOPA and its derivatives were subjected to the DPPH radical scavenging assay for the first time.
- リンク情報
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- DOI
- https://doi.org/10.3390/molecules23081943
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/30081515
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000445295500108&DestApp=WOS_CPL
- Scopus
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85052402255&origin=inward 本文へのリンクあり
- Scopus Citedby
- https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85052402255&origin=inward
- ID情報
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- DOI : 10.3390/molecules23081943
- ISSN : 1420-3049
- eISSN : 1420-3049
- PubMed ID : 30081515
- SCOPUS ID : 85052402255
- Web of Science ID : WOS:000445295500108