佐久間長彦 (Nagahiko Sakuma) - マイポータル

基本情報

所属: 名古屋市立大学大学院医学研究科心臓・腎高血圧内科学分野

J-GLOBAL ID: 201801010532162690
researchmap会員ID: B000337151

研究キーワード

研究分野

ライフサイエンス / 循環器内科学 / 動脈硬化症、脂質異常症、内分泌代謝、ビタミンC

委員歴

受賞

2018年10月

瑞友会賞臨床部門, 遺伝子疾患シトステロール血症のリポ蛋白アフェレーシスによる治療, 名古屋市立大学医学部同門会（瑞友会）

佐久間長彦

MISC

Sitosterolemia, hypercholesterolemia, and coronary artery disease

Hayato Tada, Atsushi Nohara, Akihiro Inazu, Nagahiko Sakuma, Hiroshi Mabuchi, Masa Aki Kawashiri

Journal of Atherosclerosis and Thrombosis 25 783-789 2018年1月1日
Lipoprotein Apheresis for Sitosterolemia

Nagahiko Sakuma, Hayato Tada, Hiroshi Mabuchi, Takeshi Hibino, Hirotake Kasuga

ANNALS OF INTERNAL MEDICINE 167(12) 896-899 2017年12月
Compound Heterozygotes for a Novel Mutation, Apo E1 Nagoya (Arg142Ser) and Apo E2 (Arg158Cys), with Severe Type III Hyperlipoproteinemia and Familial Hypercholesterolemia

Nagahiko Sakuma, Takeshi Hibino, Tomoaki Saeki, Takahiro Nagata, Toru Sato, Noriaki Okuda, Akira Matsunaga, Jun Sasaki

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS 21(9) 983-988 2014年
Effects of pitavastatin on remnant-like lipoprotein particle cholesterol in patients with dyslipidemia: A randomized controlled trial

Takemasa Domori, Nagahiko Sakuma, Tomoaki Saeki, Naotsuka Okayama, Takeshi Hibino, Takahiro Nagata, Takashi Joh, Sadao Suzuki, Masae Yoshikawa, Toru Sato …

Japanese Journal of Clinical Pharmacology and Therapeutics 43(6) 375-380 2012年
HDL2 Can Inhibit Further Oxidative Modification of Partially Oxidized LDL

Nagahiko Sakuma, Tomoaki Saeki, Tatsuya Ito, Takeshi Hibino, Shogo Suzuki, Mitoshi Kunimatsu, Koji Yamamoto, Syuichi Kitada

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS 17(3) 229-234 2010年
Low incidence of cardiac events in statin-administered patients in CAG study

Tomoaki Saeki, Nagahiko Sakuma, Kiyoshi Hayakawa, Kenichi Itou, Kazuaki Wakami, Nozomu Tamai, Genjiro Kimura

Journal of Atherosclerosis and Thrombosis 16(3) 172-178 2009年
Cellular redox state protects acetaldehyde-induced alteration in cardiomyocyte function by modifying Ca2+ release from sarcoplasmic reticulum

Toshiharu Oba, Yoshitaka Maeno, Masataka Nagao, Nagahiko Sakuma, Takashi Murayama

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 294(1) H121-H133 2008年1月
Oxidized HDL<inf>2</inf> is superior to native HDL<inf>2</inf> in providing cholesterol to lymphocytes via apo B,E (LDL) receptors

Nagahiko Sakuma, Nagahiko Sakuma, Tomoaki Saeki, Tatsuya Ito, Takeshi Hibino, Toshiharu Oba, Mitoshi Kunimatsu, Genjiro Kimura

Therapeutic Research 28 1365-1370 2007年8月24日
Both HDL3 and HDL2 exert a powerful anti-oxidative and protective effect against acceleration of oxidative modification of LDL by ascorbic acid

Nagahiko Sakuma, Tomoaki Saeki, Kazuhiro Yajima, Takeshi Hibino, Takayuki Yoshida, Hiromi Mizuno, Seiji Mukai, Seiichiro Sakata, Mitoshi Kunimatsu, Genjiro Kimura

Journal of Nutritional Science and Vitaminology 51(2) 75-79 2005年
Severe type III hyperlipoproteinemic patient with a new variant of Apo E1 (Arg142→Ser) and heterozygous familial hypercholesterolemia: A patient who suffered from type II diabetes mellitus during therapy

Nagahiko Sakuma, Takeshi Hibino, Takayuki Yoshida, Hiromi Mizuno, Takafumi Kato, Jun Sasaki, Akira Matsunaga, Genjiro Kimura

Therapeutic Research 25 1446-1452 2004年9月1日
Increased serum triglyceride clearance and elevated high-density lipoprotein 2 and 3 cholesterol during treatment of primary hypertriglyceridemia with bezafibrate

N Sakuma, R Ikeuchi, T Hibino, T Yoshida, S Mukai, S Akita, K Yajima, H Miyabe, T Goto, N Takada …

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL 64(9) 697-706 2003年11月
Gastric motility in patients with recurrent gastric ulcers

Takeshi Kamiya, Yuka Kobayashi, Makoto Hirako, Naoko Misu, Toshihiro Nagao, Michiko Hara, Eriko Matsuhisa, Takashi Ando, Hiroshi Adachi, Nagahiko Sakuma …

Journal of Smooth Muscle Research 38(1-2) 1-9 2002年4月
Report of the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese adults.

Yoshiya Hata, Hiroshi Mabuchi, Yasushi Saito, Hiroshige Itakura, Genshi Egusa, Hideki Ito, Tamio Teramoto, Motoo Tsushima, Norio Tada, Shinichi Oikawa …

Journal of atherosclerosis and thrombosis 9(1) 1-27 2002年1月1日
Increased serum triglyceride clearance, and elevated cholesterol of HDL<inf>3</inf> and HDL<inf>2</inf> during treatment of hypertriglyceridemia with bezafibrate

Nagahiko Sakuma, Reiko Ikeuchi, Takeshi Hibino, Seiji Mukai, Sachie Akita, Kazuhiro Yajima, Hiromichi Miyabe, Norio Takada, Takeshi Kamiya, Nobuyuki Ohte …

Therapeutic Research 23 1586-1590 2002年1月1日
Kinetics of an intravenously injected fat emulsion reflect postheparin plasma lipoprotein lipase mass and activity

N Sakuma, R Ikeuchi, T Hibino, N Ohte, N Tamai, T Kamiya, G Kimura

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 31 37-43 2002年
HDL3 exerts a more powerful antiperoxidative and protective effect against peroxidative modification of LDL than HDL2 does

Nagahiko Sakuma, Masae Yoshikawa, Takeshi Hibino, Nobuyuki Ohte, Takeshi Kamiya, Mitoshi Kunimatsu, Genjiro Kimura, Makoto Inoue

Journal of Nutritional Science and Vitaminology 48(4) 278-282 2002年
Cholesteryl ester transfer protein deficiency causes slow egg embryonation of Schistosoma japonicum

K Okumura-Noji, K Sasai, RL Zhan, H Kawaguchi, H Maruyama, T Tada, H Takahashi, M Okazaki, T Miida, N Sakuma …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(2) 305-310 2001年8月
Fine mapping of a gene responsible for regulating dietary cholesterol absorption; founder effects underlie cases of phytosterolaemia in multiple communities

MH Lee, D Gordon, J Ott, KM Lu, L Ose, T Miettinen, H Gylling, AF Stalenhoef, A Pandya, H Hidaka …

EUROPEAN JOURNAL OF HUMAN GENETICS 9(5) 375-384 2001年5月
Ascorbic acid protects against peroxidative modification of low-density lipoprotein, maintaining its recognition by LDL receptors

N. Sakuma, M. Yoshikawa, T. Hibino, T. Sato, Y. Kamiya, N. Ohte, N. Tamai, M. Kunimatsu, G. Kimura, M. Inoue

Journal of Nutritional Science and Vitaminology 47(1) 28-31 2001年
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption

MH Lee, K Lu, S Hazard, HW Yu, S Shulenin, H Hidaka, H Kojima, R Allikmets, N Sakuma, R Pegoraro …

NATURE GENETICS 27(1) 79-83 2001年1月

もっとみる

書籍等出版物

ビタミン総合事典

佐久間長彦 (担当:分担執筆, 範囲:ビタミンC 生理機能；消化.吸収.代謝)

編集者：日本ビタミン学会：朝倉書店 2010年11月
生活習慣病講座

佐久間長彦 (担当:監修, 範囲:名古屋市立大学内科学第3講座編動脈硬化、脂質異常症)

南江堂 2000年4月

佐久間長彦

基本情報

研究キーワード

研究分野

委員歴

受賞

MISC

書籍等出版物

担当経験のある科目(授業)

所属学協会

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