MISC

2017年7月1日

Cutaneous Angiolymphoid Hyperplasia in a Dog

Journal of Comparative Pathology
  • M. Michishita
  • ,
  • Y. Katori
  • ,
  • H. Sasaki
  • ,
  • R. D. Obara
  • ,
  • R. Furumoto
  • ,
  • M. Kato
  • ,
  • R. Nakahira
  • ,
  • H. Yoshimura
  • ,
  • S. Soeta
  • ,
  • T. Ishiwata
  • ,
  • K. Takahashi

157
開始ページ
57
終了ページ
60
DOI
10.1016/j.jcpa.2017.05.004

© 2017 Elsevier Ltd A 5-year-old male miniature dachshund was presented with a dermal nodule on the left forelimb that increased to 5 mm in diameter over a 2-month period. Grossly, the nodule was firm, and both the external and cut surfaces were homogeneously pale pink in colour. Microscopically, the nodule was comprised of mainly plump endothelial cells and inflammatory cells; among the latter, lymphocytes were predominant, with few scattered plasma cells, mast cells and macrophages. Lymphoid follicles with germinal centres were often observed. Mitotic figures were not observed amongst the endothelial cells. Immunohistochemically, the endothelial cells were positive for vimentin, factor VIII-related antigen and CD31, and the surrounding cells were positive for smooth muscle actin. Lymphocytes expressed CD3 or BLA36. These findings led to a diagnosis of cutaneous angiolymphoid hyperplasia. To the best of our knowledge, this is the first report of a cutaneous proliferative disorder comprising an admixture of proliferating vascular endothelial cells and lymphocytic infiltration with follicle formation in a dog.

リンク情報
DOI
https://doi.org/10.1016/j.jcpa.2017.05.004
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28735672
URL
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85021724825&origin=inward
ID情報
  • DOI : 10.1016/j.jcpa.2017.05.004
  • ISSN : 0021-9975
  • PubMed ID : 28735672
  • SCOPUS ID : 85021724825

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