Satoshi Nozaki

Profile Information

Affiliation: Genesis Healthcare Co.

J-GLOBAL ID: 201801013288554245
researchmap Member ID: B000305113

Research Areas

Life sciences / Genomics /

Papers

Comparison of [18F]FIMP, [11C]MET, and [18F]FDG PET for early-phase assessment of radiotherapy response.

Satoshi Nozaki, Yuka Nakatani, Aya Mawatari, Nina Shibata, William E Hume, Emi Hayashinaka, Yasuhiro Wada, Hisashi Doi, Yasuyoshi Watanabe

Scientific reports, 13(1) 1961-1961, Feb 3, 2023
First-in-human assessment of the novel LAT1 targeting PET probe 18F-FIMP.

Satoshi Nozaki, Yuka Nakatani, Aya Mawatari, William E Hume, Yasuhiro Wada, Akira Ishii, Masaaki Tanaka, Naohiro Tsuyuguchi, Hisashi Doi, Yasuyoshi Watanabe

Biochemical and biophysical research communications, 596 83-87, Mar 12, 2022
18F-FIMP: a LAT1-specific PET probe for discrimination between tumor tissue and inflammation

Satoshi Nozaki, Yuka Nakatani, Aya Mawatari, Nina Shibata, William E. Hume, Emi Hayashinaka, Yasuhiro Wada, Hisashi Doi, Yasuyoshi Watanabe

Scientific Reports, 9(1) 15718-15718, Dec, 2019
PET imaging of (11)C-labeled coenzyme Q10: Comparison of biodistribution between [(11)C]ubiquinol-10 and [(11)C]ubiquinone-10

Watanabe K, Nozaki S, Goto M, Kaneko KI, Hayashinaka E, Irie S, Nishiyama A, Kasai K, Fujii K, Wada Y, Mizuno K, Mizuseki K, Doi H, Watanabe Y

Biochemical and biophysical research communications, 512(3) 611-615, May, 2019 Peer-reviewed
Disulfiram enhanced delivery of orally administered copper into the central nervous system in Menkes disease mouse model.

Takao Hoshina, Satoshi Nozaki, Takashi Hamazaki, Satoshi Kudo, Yuka Nakatani, Hiroko Kodama, Haruo Shintaku, Yasuyoshi Watanabe

Journal of inherited metabolic disease, 41(6) 1285-1291, Nov, 2018 Peer-reviewed
A viable strategy for screening the effects of glycan heterogeneity on target organ adhesion and biodistribution in live mice.

Ogura A, Urano S, Tahara T, Nozaki S, Sibgatullina R, Vong K, Suzuki T, Dohmae N, Kurbangalieva A, Watanabe Y, Tanaka K

Chemical communications (Cambridge, England), 54(63) 8693-8696, Aug, 2018 Peer-reviewed
PET Imaging Analysis of Vitamin B1 Kinetics with [11C]Thiamine and its Derivative [11C]Thiamine Tetrahydrofurfuryl Disulfide in Rats

Satoshi Nozaki, Aya Mawatari, Yuka Nakatani, Emi Hayashinaka, Yasuhiro Wada, Yukihiro Nomura, Takahito Kitayoshi, Kouji Akimoto, Shinji Ninomiya, Hisashi Doi, Yasuyoshi Watanabe

Molecular Imaging and Biology, 20(6) 1-7, Mar 20, 2018 Peer-reviewed
Development of Diagnostic Techniques for Early Rheumatoid Arthritis Using Positron Emission Tomography with [C-11]PK11195 and [C-11]Ketoprofen Tracers

Satoshi Nozaki, Naoko Ozaki, Shinobu Suzuki, Miki Goto, Aya Mawatari, Yuka Nakatani, Emi Hayashinaka, Yasuhiro Wada, Hisashi Doi, Yasuyoshi Watanabe

MOLECULAR IMAGING AND BIOLOGY, 19(5) 746-753, Oct, 2017 Peer-reviewed
バイオイメージングの創薬、診断、治療への展開がんと炎症の差別化イメージング

野崎聡, 笹野有未, 山本憲一郎, 馬渡彩, 柴田仁奈, 中谷友香, 尾上嘉代, 和田康弘, 露口尚弘, 土居久志, 児玉和也, 渡辺恭良

日本癌学会総会記事, 76回 S15-4, Sep, 2017
メンケス病モデルマウスにおける銅キレート剤ジスルフィラムを用いた銅の経口投与についての検討

保科隆男, 野崎聡, 濱崎考史, 山下加奈子, 佐久間悟, 瀬戸俊之, 中谷友香, 児玉浩子, 渡辺恭良, 新宅治夫

脳と発達, 49(Suppl.) S453-S453, May, 2017 Peer-reviewed
In Vivo Gold Complex Catalysis within Live Mice

Kazuki Tsubokura, Kenward K. H. Vong, Ambara R. Pradipta, Akihiro Ogura, Sayaka Urano, Tsuyoshi Tahara, Satoshi Nozaki, Hirotaka Onoe, Yoichi Nakao, Regina Sibgatullina, Almira Kurbangalieva, Yasuyoshi Watanabe, Katsunori Tanaka

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(13) 3579-3584, Mar, 2017 Peer-reviewed
Sequential Double "Clicks" toward Structurally Well-Defined Heterogeneous N-Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo

Liliya Latypova, Regina Sibgatullina, Akihiro Ogura, Katsumasa Fujiki, Alsu Khabibrakhmanova, Tsuyoshi Tahara, Satoshi Nozaki, Sayaka Urano, Kazuki Tsubokura, Hirotaka Onoe, Yasuyoshi Watanabe, Almira Kurbangalieva, Katsunori Tanaka

ADVANCED SCIENCE, 4(2) 1600394, Feb, 2017 Peer-reviewed
Glycan multivalency effects toward albumin enable N-glycan-dependent tumor targeting

Akihiro Ogura, Tsuyoshi Tahara, Satoshi Nozaki, Hirotaka Onoe, Almira Kurbangalieva, Yasuyoshi Watanabe, Katsunori Tanaka

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 26(9) 2251-2254, May, 2016 Peer-reviewed
Visualizing Trimming Dependence of Biodistribution and Kinetics with Homo- and Heterogeneous N-Glycoclusters on Fluorescent Albumin

Akihiro Ogura, Tsuyoshi Tahara, Satoshi Nozaki, Koji Morimoto, Yasuhiko Kizuka, Shinobu Kitazume, Mitsuko Hara, Soichi Kojima, Hirotaka Onoe, Almira Kurbangalieva, Naoyuki Taniguchi, Yasuyoshi Watanabe, Katsunori Tanaka

SCIENTIFIC REPORTS, 6 21797, Feb, 2016 Peer-reviewed
In vivo imaging of advanced glycation end products (AGEs) of albumin: first observations of significantly reduced clearance and liver deposition properties in mice

Ayumi Tsutsui, Akihiro Ogura, Tsuyoshi Tahara, Satoshi Nozaki, Sayaka Urano, Mitsuko Hara, Soichi Kojima, Almira Kurbangalieva, Hirotaka Onoe, Yasuyoshi Watanabe, Naoyuki Taniguchi, Katsunori Tanaka

ORGANIC & BIOMOLECULAR CHEMISTRY, 14(24) 5755-5760, 2016 Peer-reviewed
Synthesis of C-11-Labeled Thiamine and Fursultiamine for in Vivo Molecular Imaging of Vitamin B-1 and Its Prodrug Using Positron Emission Tomography

Hisashi Doi, Aya Mawatari, Masakatsu Kanazawa, Satoshi Nozaki, Yukihiro Nomura, Takahito Kitayoshi, Kouji Aldmoto, Masaaki Suzuki, Shinji Ninomiya, Yasuyoshi Watanabe

JOURNAL OF ORGANIC CHEMISTRY, 80(12) 6250-6258, Jun, 2015 Peer-reviewed
PET Imaging Analysis with Cu-64 in Disulfiram Treatment for Aberrant Copper Biodistribution in Menkes Disease Mouse Model

Shiho Nomura, Satoshi Nozaki, Takashi Hamazaki, Taisuke Takeda, Eiichi Ninomiya, Satoshi Kudo, Emi Hayashinaka, Yasuhiro Wada, Tomoko Hiroki, Chie Fujisawa, Hiroko Kodama, Haruo Shintaku, Yasuyoshi Watanabe

JOURNAL OF NUCLEAR MEDICINE, 55(5) 845-851, May, 2014 Peer-reviewed
6.PETによるC-11標識フルスルチアミン・チアミンの体内動態(第435回研究協議会研究発表要旨,ビタミンB研究委員会)

渡辺恭良, 土居久志, 馬渡彩, 金澤奨勝, 野崎聡, 中谷友香, 野村之博, 秋元浩二, 二宮伸二

ビタミン, 88(5) 309-310, 2014
小動物用PETイメージングによるメンケス病モデルマウスを用いた新規治療法の開発と評価

野村志保, 野崎聡, 濱崎考史, 二宮英一, 林中恵美, 和田康弘, 渡辺恭良, 新宅治夫

日本周産期・新生児医学会雑誌, 49(2) 631-631, Jun, 2013 Peer-reviewed
A conformationally fixed analog of the peptide mimic Grb2-SH2 domain: Synthesis and evaluation against the A431 cancer cell

Takayuki Iwata, Katsunori Tanaka, Tsuyoshi Tahara, Satoshi Nozaki, Hirotaka Onoe, Yasuyoshi Watanabe, Koichi Fukase

Molecular BioSystems, 9(5) 1019-1025, May, 2013 Peer-reviewed

Misc.

チアミンおよびフルスルチアミンの¹¹C-標識PETプローブの合成

馬渡彩, 野崎聡, 二宮伸二, 渡辺恭良, 土居久志

ビタミン = Vitamins, 91(3) 190-192, Mar, 2017
[F-18]AA-7: A novel PET tracer for imaging L-type amino acid transporter 1 (LAT1)-positive tumors

Satoshi Nozaki, Yuka Nakatani, Yumi Sasano, Kenichiro Yamamoto, William Hume, Yasuhiro Wada, Susumu Shiomi, Naohiro Tsuyuguchi, Kazuya Kodama, Yasuyoshi Watanabe

JOURNAL OF NUCLEAR MEDICINE, 56(3), May, 2015
Realization of [C-11]CH3-incorporated thiamine and fursultiamin for PET molecular imaging of vitamin B-1

Hisashi Doi, Aya Mawatari, Masakatsu Kanazawa, Satoshi Nozaki, Yukihiro Nomura, Kouji Akimoto, Shinji Ninomiya, Masaaki Suzuki, Yasuyoshi Watanabe

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 56 S98-S98, May, 2013
バイオPET薬剤の安全性評価のための考察

豊田浩士, 矢野恒夫, 長谷川功紀, 野崎聡, 中村郁子, 片岡洋祐

JSMI Rep, 5(2) 83-83, May, 2012
単糖のデンドリマー型クラスターの合成とPETイメージング

LI Haosheng, SIWU Eric R. O, 岩田隆幸, 野崎聡, 長谷川功紀, 渡辺恭良, 田中克典, 深瀬浩一

日本化学会講演予稿集, 92nd(4) 1672, Mar 9, 2012
microPET imagingによるMenkes病モデルマウスをもちいたヒスチジン銅、ジスルフィラム併用療法の効果検討

二宮英一, 武田泰輔, 野村志保, 藤岡弘季, 齊藤三佳, 野崎聡, 和田康弘, 渡辺恭良, 新宅治夫

日本未熟児新生児学会雑誌, 23(3) 579-579, Oct, 2011
microPET imagingによるメンケス病モデルマウスをもちいたヒスチジン銅、ジスルフィラム併用療法の効果検討

武田泰輔, 藤岡弘季, 野村志保, 二宮英一, 野崎聡, 和田康弘, 渡辺恭良, 新宅治夫

日本先天代謝異常学会雑誌, 27(2) 233-233, Oct, 2011
Development of Early Diagnostic Techniques for Rheumatoid Arthritis Using Carbone Eleven Labeled PK11195 and Carbone Eleven Labeled Ketoprofen

Satoshi Nozaki, Sinobu Suzuki, Naoko Ozaki, Jeffrey Encinas, Hisashi Doi, Yasuhiro Wada, Masaaki Suzuki, Yasuyoshi Watanabe

ARTHRITIS AND RHEUMATISM, 63(10) S74-S75, Oct, 2011
microPET imagingによるヒスチジン銅、ジスルフィラム併用療法の効果検討

武田泰輔, 野村志保, 二宮英一, 藤岡弘季, 藤澤知恵, 児玉浩子, 野崎聡, 和田康弘, 渡辺恭良, 新宅治夫

日本小児科学会雑誌, 115(2) 327-327, Feb, 2011
microPET imagingによるヒスチジン銅、ジスルフィラム併用療法の効果検討

武田泰輔, 野村志保, 二宮英一, 藤岡弘季, 野崎聡, 和田康弘, 渡辺恭良, 新宅治夫

日本未熟児新生児学会雑誌, 22(3) 517-517, Oct, 2010
ポリリジンデンドリマー型糖鎖クラスターの効率的合成を基盤としたN‐結合型糖鎖の非侵襲的イメージング

田中克典, SIWU Eric R.O, 南香莉, 長谷川功紀, 野崎聡, 金山洋介, 小山幸一, 渡辺恭良, 深瀬浩一

日本化学会バイオテクノロジー部会シンポジウム講演要旨集, 13th 153, Sep 24, 2010
Azaelectrocyclization-Based Labeling of Proteins and Cell Surfaces: Application to Noninvasive Imaging of N-Glycans

Tanaka Katsunori, Minami Kaori, Siwu Eric R. O, Masuyama Tatsuro, Koyama Koichi, Yokoi Satomi, Hasegawa Koki, Tahara Tsuyoshi, Mizuma Hiroshi, Nozaki Satoshi, Kanayama Yousuke, Wada Yasuhiro, Onoe Hirotaka, Watanabe Yasuyoshi, Fukase Koichi

Symposium on the Chemistry of Natural Products, symposium papers, 52 25-30, 2010
蛍光およびPETによるN‐結合型糖鎖クラスターのインビボイメージング

SIWU Eric R. O, 南香莉, 長谷川功紀, 野崎聡, 金山洋介, 小山幸一, 渡辺恭良, 田中克典, 深瀬浩一

日本糖質学会年会要旨集, 29th 48, Aug 10, 2009
CENTRAL CHANGES IN EXPERIMENTAL GLAUCOMA

Kazuyuki Imamura, Hirotaka Onoe, Masamitsu Shimazawa, Satoshi Nozaki, Hiroshi Mizuma, Yasuhiro Wada, Kayo Onoe, Kiyoshi Ishii, Chihiro Mayama, Takazumi Taniguchi, Masaaki Sasaoka, Hajime Yamanaka, Hideaki Hara, Shigeru Tanaka, Makoto Araie, Yasuyoshi Watanabe

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 524-524, 2009
Preliminary study for multiple molecular imaging: PET probe imaging using semiconductor Compton camera

Yousuke Kanayama, Shinji Motomura, Tomonori Fukuchi, Hiromitsu Haba, Satoshi Nozaki, Yasuyoshi Watanabe, Shuichi Enomoto

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 128 66-66, 2008
Mental fatigue-induced decrease in levels of several plasma amino acids

K. Mizuno, M. Tanaka, S. Nozaki, K. Yamaguti, H. Mizuma, T. Sasabe, T. Sugino, T. Shirai, Y. Kataoka, Y. Kajimoto, H. Kuratsune, O. Kajimoto, Y. Watanabe

JOURNAL OF NEURAL TRANSMISSION, 114(5) 555-561, May, 2007
Intracerebroventricular administration of secretin alters monoaminergic tone

S Nozaki, R Nakata, H Mizuma, S Takashino, N Nishimura, R Kohashi, Y Watanabe

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 17 S151-S151, Aug, 2002
Improvement of 5,7-dihydroxytryptamine-induced behaviors in immature rat by repeated administration of 6R-tetrahydroblopterin

H Mizuma, R Nakata, S Nozaki, S Takashino, H Iizuka, H Tohyama, N Nishimura, Y Watanabe, R Kohashi

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 17 S162-S162, Aug, 2002

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