Satoshi Fujimoto

Profile Information

Affiliation: Faculty of Medical Sciences, Kyushu University

Degree: Ph.D.(Kyoto University)

ORCID ID: https://orcid.org/0000-0002-7618-5502
J-GLOBAL ID: 201101040494720874
researchmap Member ID: B000002577

External link: https://scholar.google.co.jp/citations?user=8KNz1N0AAAAJ

脳神経系はどのように作られるのかという疑問をきっかけに、生物とは何か？自分とは何か？ということ理解すべく、日々研究しています。

Research Interests

Research Areas

Life sciences / Neuroscience - general /

Research History

Apr, 2017 - Present

Assistant professor, Faculty of Medical Sceinces, Kyushu University
Apr, 2017 - Mar, 2018

Visiting researcher, Laboratory for Sensory Circuit Formation, RIKEN CDB
Aug, 2011 - Mar, 2017

Reseach Scientist, Laboratory for Sensory Circuit Formation, RIKEN CDB
Apr, 2010 - Jul, 2011

助教, 千葉大学大学院医学研究院

Education

Apr, 2006 - Mar, 2010

Graduate School of Biostudies, Kyoto University
Apr, 2004 - Mar, 2006

Graduate School of Biostudies, Kyoto University
Apr, 2000 - Mar, 2004

Faculty of Pharmaceutical Sciences, Kyoto University
- Mar, 1999

福岡県立福岡高等学校

Papers

Microglia are dispensable for developmental dendrite pruning of mitral cells in mice.

Tetsushi Niiyama, Satoshi Fujimoto, Takeshi Imai

eNeuro, Oct 27, 2023 Peer-reviewed
Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice.

Satoshi Fujimoto, Marcus N Leiwe, Shuhei Aihara, Richi Sakaguchi, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

Developmental cell, May 30, 2023 Peer-reviewed
Effective Hand Rearing of Neonatal Mice for Developmental Studies

Leiwe Marcus, Satoshi Fujimoto, Takeshi Imai

Bio-protocol, 13(11), 2023 Peer-reviewed
BMPR-2 gates activity-dependent stabilization of primary dendrites during mitral cell remodeling.

Shuhei Aihara, Satoshi Fujimoto, Richi Sakaguchi, Takeshi Imai

Cell reports, 35(12) 109276-109276, Jun 22, 2021 Peer-reviewed
Post hoc Correction of Chromatic Aberrations in Large-Scale Volumetric Images in Confocal Microscopy.

Marcus N Leiwe, Satoshi Fujimoto, Takeshi Imai

Frontiers in neuroanatomy, 15 760063-760063, 2021 Peer-reviewed
Distorted coarse axon targeting and reduced dendrite connectivity underlie Dysosmia after olfactory axon injury

Aya Murai, Ryo Iwata, Satoshi Fujimoto, Shuhei Aihara, Akio Tsuboi, Yuko Muroyama, Tetsuichiro Saito, Kazunori Nishizaki, Takeshi Imai

eNeuro, 3(5), Sep 1, 2016 Peer-reviewed
Super-Resolution Mapping of Neuronal Circuitry With an Index-Optimized Clearing Agent

Meng-Tsen Ke, Yasuhiro Nakai, Satoshi Fujimoto, Rie Takayama, Shuhei Yoshida, Tomoya S. Kitajima, Makoto Sato, Takeshi Imai

CELL REPORTS, 14(11) 2718-2732, Mar, 2016 Peer-reviewed
Optical Clearing Using SeeDB.

Meng-Tsen Ke, Satoshi Fujimoto, Takeshi Imai

Bio-protocol, 4(3) e1042, Feb, 2014 Peer-reviewedInvited
SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

Meng-Tsen Ke, Satoshi Fujimoto, Takeshi Imai

NATURE NEUROSCIENCE, 16(8) 1154-U246, Aug, 2013 Peer-reviewed
Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

Nao Hiramoto-Yamaki, Shingo Takeuchi, Shuhei Ueda, Kohei Harada, Satoshi Fujimoto, Manabu Negishi, Hironori Katoh

JOURNAL OF CELL BIOLOGY, 190(3) 461-477, Aug, 2010 Peer-reviewed
RhoG Promotes Neural Progenitor Cell Proliferation in Mouse Cerebral Cortex

Satoshi Fujimoto, Manabu Negishi, Hironori Katoh

MOLECULAR BIOLOGY OF THE CELL, 20(23) 4941-4950, Dec, 2009 Peer-reviewed
Plexin-B1 is a GTPase activating protein for M-Ras, remodelling dendrite morphology

Yasuhiro Saito, Izumi Oinuma, Satoshi Fujimoto, Manabu Negishi

EMBO REPORTS, 10(6) 614-621, Jun, 2009 Peer-reviewed
Dock4 Regulates Dendritic Development in Hippocampal Neurons

Shuhei Ueda, Satoshi Fujimoto, Kiyo Hiramoto, Manabu Negishi, Hironori Katoh

JOURNAL OF NEUROSCIENCE RESEARCH, 86(14) 3052-3061, Nov, 2008 Peer-reviewed
Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain

H Katoh, S Fujimoto, C Ishida, Y Ishikawa, M Negishi

BRAIN RESEARCH, 1073 103-108, Feb, 2006 Peer-reviewed

Misc.

僧帽細胞が樹状突起刈り込みによって単一の主樹状突起を確立するためのシナプス競合の仕組み

Satoshi Fujimoto

Feb, 2024
嗅球における1僧帽細胞-1糸球体接続ルールを保証するシナプス競合の仕組み

藤本聡志, 今井猛

日本味と匂学会誌, 30(2) 101-109, Nov, 2023
発達期の樹状突起刈り込みを制御するシナプス競合のメカニズム

藤本聡志, 今井猛

医学のあゆみ, 286巻(5号) 365-371, Jul 29, 2023
Automated neuronal reconstruction with super-multicolour fluorescence imaging

Marcus N. Leiwe, Satoshi Fujimoto, Toshikazu Baba, Daichi Moriyasu, Biswanath Saha, Richi Sakaguchi, Shigenori Inagaki, Takeshi Imai

Oct 20, 2022
BMPR-2 gates activity-dependent stabilization of dendrites during mitral cell remodeling

Shuhei Aihara, Satoshi Fujimoto, Richi Sakaguchi, Takeshi Imai

bioRxiv, Oct 30, 2020
Spontaneous activity generated within the olfactory bulb establishes the discrete wiring of mitral cell dendrites

Satoshi Fujimoto, Marcus N Leiwe, Richi Sakaguchi, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

bioRxiv, 625616, May, 2019
SeeDB2: A tissue clearing method for high-resolution fluorescence imaging

Satoshi Fujimoto, Meng-Tsen Ke, Richi Sakaguchi, Takeshi Imai

Jikken Igaku, 37(6) 963-969, Apr, 2019 Invited
Spontaneous activity governs the dendrite pruning of mitral cells to establish discrete connectivity

Satoshi Fujimoto, Marcus N. Leiwe, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

CHEMICAL SENSES, 41(9) E146-E146, Nov, 2016
樹状突起の形態形成におけるDockファミリーの役割

加藤裕教, 上田修平, 倉本和也, 藤本聡志, 根岸学

第32回日本神経科学大会, Sep, 2009
The role of Dock family Rho-GEFs in dendrite morphogenesis

Hironori Katoh, Shuhei Ueda, Kazuya Kuramoto, Satoshi Fujimoto, Manabu Negishi

NEUROSCIENCE RESEARCH, 65 S13-S13, 2009
RhoG regulates neural progenitor cell proliferation through PI3K

S. FUJIMOTO, M. NEGISHI, H. KATOH

the 38th annual meeting of the Society for Neuroscience, Nov 17, 2008 Peer-reviewed
The Rac activator Dock4 regulates dendritic development in hippocampal neurons

Shuhei Ueda, Satoshi Fujimoto, Kiyo Hiramoto, Manabu Negishi, Hironori Katoh

NEUROSCIENCE RESEARCH, 61 S37-S37, 2008
RhoG regulates neural progenitor cell proliferation in mouse cerebral cortex

Satoshi Fujimoto, Manabu Negishi, Hironori Katoh

NEUROSCIENCE RESEARCH, 58 S200-S200, 2007

Presentations

Mechanisms of synaptic competition for establishing the “one mitral cell – one glomerulus” connection rule

Satoshi Fujimoto, Marcus Leiwe, Shuhei Aihara, Richi Sakaguchi, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

ISMNTOP2023, Nov 26, 2023 Invited
発達期の樹状突起刈り込みを制御するシナプス競合の分子機構

藤本聡志, Marcus N. Leiwe, 藍原周平, 坂口理智, 室山優子, 小早川令子, 小早川高, 斎藤哲一郎, 今井猛

第96回日本生化学会大会, Oct 31, 2023
Activity-dependent local protection and lateral inhibition control developmental dendrite pruning in mitral cells

Satoshi Fujimoto, Marcus Leiwe, Shuhei Aihara, Richi Sakaguchi, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

Axon 2023 - Development, Plasticity & Regeneration of Neural Circuits, Sep 27, 2023
Activity-dependent lateral inhibition signals establish a discrete receptive field of a neuron

Satoshi Fujimoto, Marcus N Leiwe, Shuhei Aihara, Richi Sakaguchi, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

The 46th Annual Meeting of the Japan Neuroscience Society, Aug 2, 2023
シナプス競合による樹状突起刈り込みのメカニズム

藤本聡志

第5回これからの神経回路研究の会, Mar 25, 2023
Activity-dependent lateral inhibition signals for synaptic competition

Satoshi Fujimoto

EMBO Workshop - Mechanisms of neuronal remodelling, Mar 12, 2023
Synaptic competition in nerual circuit development

Satoshi Fujimoto

Mar 23, 2022
Activity-dependent competition within a neuron ensures the discrete wiring of mitral cell dendrites

Satoshi Fujimoto, Marcus N. Leiwe, Shuhei Aihara, Richi Sakaguchi, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

Jul, 2021
Activity-dependent competition within a neuron ensures the discrete wiring of mitral cell dendrites

Satoshi Fujimoto, Takeshi Imai

NIG meeting, Dec 11, 2020
Activity-dependent competition within a neuron ensures the discrete wiring of mitral cell dendrites

Satoshi Fujimoto, Marcus N. Leiwe, Shuhei Aihara, Richi Sakaguchi, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

CSHL Meeting Molecular Mechanisms of Neuronal Connectivity, Sep 8, 2020
生後発達期の嗅球における自発神経活動依存的な回路形成

藤本聡志

第42回日本分子生物学会 Invited
Spontaneous Activity-Dependent Discrete Circuit Formation in the Developing Olfactory Bulb

Satoshi Fujimoto, Marcus N. Leiwe, Yuko Muroyama, Tetsuichiro Saito, Takeshi Imai

ISMNTOP/YRUF/AISCRIB2018, Dec, 2018
発達期の嗅球における自発神経活動依存的な神経回路形成

藤本聡志, Marcus N. Leiwe, 室山優子, 斎藤哲一郎, 今井猛

第69回西日本生理学会, Oct, 2018
Developmental change of spontaneous network activity regulates dendrite pruning of mitral cells to establish discrete connectivity

Satoshi Fujimoto, Marcus N. Leiwe, Yuko Muroyama, Tetsuichiro Saito, Takeshi Imai

ISMNTOP/YRUF/AISCRIB2017, Nov, 2017
発達期の嗅球における自発神経活動パターンの変化と回路形成

藤本聡志

発生生物学会秋季シンポジウム, Oct 19, 2016 Invited
Developmentally-regulated spontaneous network activity governs dendrite pruning of mitral cells to establish discrete connectivity.

Satoshi Fujimoto, Marcus N. Leiwe, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

CSHL meeting : Axon Guidance, Synapse Formation & Regeneration, Sep, 2016
Spontaneous activity governs the dendrite pruning of mitral cells to establish discrete connectivity.

Satoshi Fujimoto, Marcus N. Leiwe, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

JNSS Neuroscience2016, Jul, 2016
Spontaneous activity governs the dendrite pruning of mitral cells to establish discrete connectivity.

Satoshi Fujimoto, Marcus N. Leiwe, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai

ISOT2016, Jun, 2016
Spontaneous neuronal activity is required for dendrite pruning of olfactory mitral cells in early postnatal development.

Satoshi Fujimoto, Yuko Muroyama, Tetsuichiro Saito, Takeshi Imai

NIG meeting, Dec, 2015
Spontaneous neuronal activity is required for dendrite pruning of olfactory mitral cells in early postnatal development.

Satoshi Fujimoto, Yuko Muroyama, Tetsuichiro Saito, Takeshi Imai

The 45th annual meeting of the Society for Neuroscience, Oct, 2015

Research Projects

樹状突起の刈り込みを制御するシナプス競合の分⼦機構

Nov, 2023 - Nov, 2024
Elucidating the molecular basis for synaptic competition during development

Nov, 2023 - Nov, 2024

Satoshi Fujimoto
Mechanisms of spontaneous activity-dependent synaptic competition in dendrite remodeling

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2023
自発神経活動の脱同期による樹状突起の接続特異性決定機構

科学研究費補助金(若手研究B), 文部科学省, Apr, 2017 - Mar, 2019

藤本聡志
Formation of discrete connectivity by the timing of spontaneous activity

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2015 - 2016

Fujimoto Satoshi
新奇トランスシナプス遺伝子改変技術の開発

科学研究費補助金(挑戦的萌芽研究), 挑戦的萌芽研究, 文部科学省, Apr, 2012 - Mar, 2013

藤本聡志

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