論文

査読有り
2011年

Acute Effects of Shortly Pre- Versus Postprandial Aerobic Exercise on Postprandial Lipoprotein Metabolism in Healthy but Sedentary Young Women

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
  • Sayuki Hashimoto
  • ,
  • Kayo Ootani
  • ,
  • Sanae Hayashi
  • ,
  • Michitaka Naito

18
10
開始ページ
891
終了ページ
900
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.5551/jat.8482
出版者・発行元
JAPAN ATHEROSCLEROSIS SOC

Aim: To compare the acute effects of shortly pre- vs. postprandial exercise on postprandial lipid metabolism in healthy but sedentary young Japanese women.
Methods: Healthy young Japanese women with a sedentary lifestyle, normal weight (18.5 <= BMI< 25), normal ovarian cycle, and apolipoprotein E3/3 were selected as participants. A single bout of walking exercise was performed 20 min after (Exp. 1) or 50 min before (Exp. 2) the intake of oral fat tolerance test (OFTT) cream (1 g/kg body weight) at about 50% (V) over doto2max for 30 min on a motorized treadmill. A control trial without exercise was also performed in each experiment. Each subject performed 2 trials in a randomized, cross-over design. Venous blood samples were drawn before the preprandial exercise (-1 h, Exp. 1 only) and before (0 h) and 1, 2, 4 and 6 h after the fat intake for the determination of triglyceride (TG), apolipoprotein B-48 (apoB48), remnant-like particle-TG (RLP-TG), lactate, free fatty acid (FFA), insulin, and glucose.
Results: In both experiments, postprandial serum TG concentrations in the exercise group were lower, but not significantly, than those in the control. In Exp. 1, incremental areas under the curve (IAUC) for TG and RLP-TG were slightly, but not significantly, smaller in the postprandial exercise group than the control. The values of apoB48, a marker of the chylomicron particle number, at 2, 4, and 6 h after the fat intake and IAUC for apoB48 were significantly lower in the postprandial exercise group than the control. In Exp. 2, IAUC for TG, RLP-TG, and apoB48 were not significantly different between the two groups.
Conclusion: The present findings suggest that postprandial, but not preprandial, exercise may reduce the number of chylomicrons and chylomicron remnants and improve exogenous lipoprotein metabolism. Postprandial exercise is more effective for improving postprandial lipoprotein metabolism than preprandial exercise.

Web of Science ® 被引用回数 : 11

リンク情報
DOI
https://doi.org/10.5551/jat.8482
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/21685706
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000297673000007&DestApp=WOS_CPL