論文

査読有り
2017年8月

Adjustment of the Arabidopsis circadian oscillator by sugar signalling dictates the regulation of starch metabolism

SCIENTIFIC REPORTS
  • Motohide Seki
  • ,
  • Takayuki Ohara
  • ,
  • Timothy J. Hearn
  • ,
  • Alexander Frank
  • ,
  • Viviane C. H. da Silva
  • ,
  • Camila Caldana
  • ,
  • Alex A. R. Webb
  • ,
  • Akiko Satake

7
8305
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41598-017-08325-y
出版者・発行元
NATURE PUBLISHING GROUP

Arabidopsis plants store part of the carbon fixed by photosynthesis as starch to sustain growth at night. Two competing hypotheses have been proposed to explain this diel starch turnover based on either the measurement of starch abundance with respect to circadian time, or the sensing of sugars to feedback to the circadian oscillator to dynamically adjust the timing of starch turnover. We report a phase oscillator model that permitted derivation of the ideal responses of the circadian regulation of starch breakdown to maintain sucrose homeostasis. Testing the model predictions using a sugar-unresponsive mutant of Arabidopsis demonstrated that the dynamics of starch turnover arise from the circadian clock measuring and responding to the rate of change of cellular sucrose. Our theory and experiments suggest that starch turnover is controlled by the circadian clock acting as a dynamic homeostat responding to sucrose signals to maintain carbon homeostasis.

Web of Science ® 被引用回数 : 15

リンク情報
DOI
https://doi.org/10.1038/s41598-017-08325-y
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28814797
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000407675300001&DestApp=WOS_CPL

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