Takahiro Seno

Profile Information

Affiliation: Assistant Professor, Inflammation and Immunology, Kyoto Prefectural University of Medicine

Degree: Doctor of Philosophy (Medicine)(Feb, 2012, Kyoto Prefectural University of Medicine)

J-GLOBAL ID: 202101003019039679
researchmap Member ID: R000027036

Research Interests

Major Research Areas

Life sciences / Allergies and connective tissue disease /

Major Research History

Jul, 2017 - Mar, 2021

Research Fellow, Surgery, Boston Children's Hospital, Harvard Medical School

Committee Memberships

Councilor, Japanese Society of Rheumatology

Awards

Apr, 2022

Excellent Poster Award, An optimal choice of biologics switched from JAK inhibitors for patients with rheumatoid arthritis -single-center retrospective analysis-, Japanese Society of Rheumatology

Papers

Deciphering the association between biopsy-confirmed systemic small vessel vasculitis and Epstein-Barr virus-positive polymorphic B-cell lymphoproliferation.

Atsuhiko Sunaga, Takahiro Seno, Satoshi Omura, Takuya Inoue, Aya Miyagawa-Hayashino, Ikoi Omatsu, Makoto Wada, Masataka Kohno, Yutaka Kawahito

Modern rheumatology case reports, May 29, 2024
Optimal Dose of Intravenous Cyclophosphamide during remission induction therapy in ANCA-associated vasculitis: a retrospective cohort study of J-CANVAS.

Hideaki Sofue, Takashi Kida, Aiko Hirano, Satoshi Omura, Masatoshi Kadoya, Daiki Nakagomi, Yoshiyuki Abe, Naoho Takizawa, Atsushi Nomura, Yuji Kukida …

Modern rheumatology, Oct 6, 2023
Therapeutic activation of endothelial sphingosine-1-phosphate receptor 1 by chaperone-bound S1P suppresses proliferative retinal neovascularization.

Colin Niaudet, Bongnam Jung, Andrew Kuo, Steven Swendeman, Edward Bull, Takahiro Seno, Reed Crocker, Zhongjie Fu, Lois E H Smith, Timothy Hla

EMBO molecular medicine, e16645, Mar 13, 2023
胸膜炎が主症状として発症した乾癬性関節炎の症例

妹尾高宏, 佐川友哉, 井上拓也, 藤井渉, 川人豊

日本呼吸器学会誌, 12(増刊) 262-262, Mar, 2023
Association between early immunophenotypic changes and therapeutic response of belimumab in patients with systemic lupus erythematosus.

Aiko Hirano, Kazuki Fujioka, Takashi Kida, Satoshi Omura, Hideaki Sofue, Aki Sakashita, Tomoya Sagawa, Yu Isoda, Akiko Kasahara, Risa Sagawa …

Lupus, 9612033221137249-9612033221137249, Oct 31, 2022
Effectiveness and safety of allergen immunotherapy in patients with allergic rhinitis complicated by rheumatic autoimmune diseases: a case series study.

Kazuki Fujioka, Akiko Kasahara, Takashi Kida, Wataru Fujii, Takahiro Seno, Makoto Wada, Masataka Kohno, Yutaka Kawahito

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 18(1) 63-63, Jul 11, 2022
Risk factors for cytomegalovirus disease with cytomegalovirus re-activation in patients with rheumatic disease.

Shunya Kaneshita, Takashi Kida, Isao Yokota, Hidetake Nagahara, Takahiro Seno, Makoto Wada, Masataka Kohno, Yutaka Kawahito

Modern rheumatology, 30(1) 109-115, Jan, 2020
関節リウマチに対する漢方薬併用の有用性

谷口大吾, 妹尾高宏, 小田良, 遠山将吾, 川人豊, 徳永大作, 久保俊一

日本東洋医学雑誌, 70(3) 254-259, Jul, 2019
Efficacy of abatacept in patients with rheumatoid arthritis, as assessed by magnetic resonance imaging of bilateral hands.

Yuji Kukida, Akiko Kasahara, Takahiro Seno, Takuya Inoue, Risa Sagawa, Takashi Kida, Amane Nakabayashi, Hidetake Nagahara, Ken Murakami, Toshifumi Sugitani …

International journal of rheumatic diseases, 21(9) 1678-1685, Sep, 2018
Thrombopoietin receptor agonist, splenectomy and intravenous immunoglobulin for immune thrombocytopaenia with systemic lupus erythematosus.

Hideaki Sofue, Takashi Kida, Takahiro Seno, Masataka Kohno, Yutaka Kawahito

Rheumatology (Oxford, England), 57(8) 1495-1497, Aug 1, 2018
Roles of high-mobility group box 1 and thrombin in murine pulmonary fibrosis and the therapeutic potential of thrombomodulin.

Takashi Kida, Takahiro Seno, Hidetake Nagahara, Takuya Inoue, Amane Nakabayashi, Yuji Kukida, Kazuki Fujioka, Wataru Fujii, Makoto Wada, Masataka Kohno …

American journal of physiology. Lung cellular and molecular physiology, 314(3) L473-L483, Mar 1, 2018
Role of allograft inflammatory factor-1 in bleomycin-induced lung fibrosis.

Hidetake Nagahara, Takahiro Seno, Aihiro Yamamoto, Hiroshi Obayashi, Takuya Inoue, Takashi Kida, Amane Nakabayashi, Yuji Kukida, Kazuki Fujioka, Wataru Fujii …

Biochemical and biophysical research communications, 495(2) 1901-1907, Jan 8, 2018
Intravascular lymphoma in a rheumatoid arthritis patient following short-term methotrexate treatment.

Takashi Kida, Masataka Kohno, Yoshiaki Chinen, Aiko Tominaga, Takahiro Seno, Taku Tsukamoto, Junya Kuroda, Yutaka Kawahito

Rheumatology (Oxford, England), 56(2) 318-320, Feb, 2017
Spontaneous flexor tendon rupture in systemic lupus erythematosus: A case report.

Ryo Oda, Hiroyoshi Fujiwara, Daisaku Tokunaga, Aiko Kishida, Daigo Taniguchi, Takahiro Seno, Yutaka Kawahito, Toshikazu Kubo

Modern rheumatology, 26(5) 794-7, Sep, 2016
Prediction of radiographic progression in synovitis-positive joints on maximum intensity projection of magnetic resonance imaging in rheumatoid arthritis.

Takanori Akai, Daigo Taniguchi, Ryo Oda, Maki Asada, Shogo Toyama, Daisaku Tokunaga, Takahiro Seno, Yutaka Kawahito, Yosuke Fujii, Hirotoshi Ito …

Clinical rheumatology, 35(4) 873-8, Apr, 2016
Allograft inflammatory factor-1 in the pathogenesis of bleomycin-induced acute lung injury.

Hidetake Nagahara, Aihiro Yamamoto, Takahiro Seno, Hiroshi Obayashi, Takashi Kida, Amane Nakabayashi, Yuji Kukida, Kazuki Fujioka, Wataru Fujii, Ken Murakami …

Bioscience trends, 10(1) 47-53, Feb, 2016
Once-weekly teriparatide improves glucocorticoid-induced osteoporosis in patients with inadequate response to bisphosphonates.

Takahiro Seno, Aihiro Yamamoto, Yuji Kukida, Aiko Hirano, Takashi Kida, Amane Nakabayashi, Kazuki Fujioka, Hidetake Nagahara, Wataru Fujii, Ken Murakami …

SpringerPlus, 5(1) 1056-1056, 2016
Monocarboxylate transporter 4, associated with the acidification of synovial fluid, is a novel therapeutic target for inflammatory arthritis.

Wataru Fujii, Yutaka Kawahito, Hidetake Nagahara, Yuji Kukida, Takahiro Seno, Aihiro Yamamoto, Masataka Kohno, Ryo Oda, Daigo Taniguchi, Hiroyoshi Fujiwara …

Arthritis & rheumatology (Hoboken, N.J.), 67(11) 2888-96, Nov, 2015
アバタセプト皮下注射の長期安全性

妹尾高宏, 川人豊

リウマチ科, 54(1) 90-95, Jul, 2015
Inhibition of osteoclastogenesis by osteoblast-like cells genetically engineered to produce interleukin-10.

Kazuki Fujioka, Tsunao Kishida, Akika Ejima, Kenta Yamamoto, Wataru Fujii, Ken Murakami, Takahiro Seno, Aihiro Yamamoto, Masataka Kohno, Ryo Oda …

Biochemical and biophysical research communications, 456(3) 785-91, Jan 16, 2015

Misc.

139

下顎骨病変を伴うびまん性硬化性骨髄炎(Diffuse sclerosing osteomyelitis of the mandible:DSOM)で発症したSAPHO症候群の一例

中西優市郎, 妹尾高宏, 金下峻也, 藤岡数記, 和田誠, 河野正孝, 川人豊

日本リウマチ学会総会・学術集会プログラム・抄録集, 63回 749-749, Mar, 2019
Incidence, Predictors, and Outcome of Diffuse Alveolar Hemorrhage in Patients with MPO-ANCA Positive Microscopic Polyangiitis: A Multi-Center Retrospective Cohort Study

Takashi Kida, Shunya Kaneshita, Takuya Inoue, Amane Nakabayashi, Yuji Kukida, Kazuki Fujioka, Hidetake Nagahara, Makoto Wada, Takahiro Seno, Masataka Kohno …

ARTHRITIS & RHEUMATOLOGY, 69, Oct, 2017
The Difference in the Clinical Characteristics between Cytomegalovirus Disease and Asymptomatic Cytomegalovirus Reactivation in Rheumatic Diseases

Shunya Kaneshita, Takashi Kida, Hidetake Nagahara, Yuko Kitagawa, Hideaki Sofue, Akiko Kasahara, Risa Sagawa, Takuya Inoue, Amane Nakabayashi, Yuji Kukida …

ARTHRITIS & RHEUMATOLOGY, 69, Oct, 2017
関節リウマチ発症を契機にプロテインC欠損症に伴う肺梗塞を発症した1例

井上拓也, 藤井渉, 祖父江秀晃, 藤岡数記, 妹尾高宏, 河野正孝, 川人豊, 村上憲, 森下英理子

臨床リウマチ, 29(2) 98-106, Jun, 2017
関節リウマチの治療病理・病態・バイオマーカートシリズマブ使用における関節リウマチ新規疾患活動性バイオマーカー

妹尾高宏, 河野正孝, 佐川里紗, 笠原亜希子, 祖父江秀晃, 井上拓也, 木田節, 中林周, 茎田祐司, 藤岡数記 …

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 425-425, Mar, 2017
リウマチ性疾患の合併症ビスフォスフォネート効果不十分なステロイド性骨粗鬆症における週1回投与テリパラチドからデノスマブスイッチ後の治療成績

妹尾高宏, 木田節, 北川裕子, 祖父江秀晃, 井上拓也, 笠原亜希子, 佐川里紗, 金下峻也, 藤岡数記, 和田誠 …

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 434-434, Mar, 2017
リウマチ性疾患の新しい治療法膠原病における新規抗C型肝炎ウイルス療法の有用性についての検討

木田節, 北川裕子, 祖父江秀晃, 井上拓也, 笠原亜希子, 金下峻也, 佐川里紗, 中林周, 茎田祐司, 藤岡数記 …

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 437-437, Mar, 2017
関節リウマチの治療評価と予測関節リウマチ手指変形のクラスター解析を用いた包括的評価の試み

遠山将吾, 小田良, 谷口大吾, 池田亮介, 妹尾高宏, 川人豊, 生駒和也, 徳永大作, 藤原浩芳, 久保俊一

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 438-438, Mar, 2017
多発性筋炎・皮膚筋炎ステロイド抵抗性の嚥下障害に対しIVIG(免疫グロブリン大量静注)が著効した抗TIF-1γ(transcription intermediary factor 1γ)抗体陽性皮膚筋炎の1例

井上拓也, 北川裕子, 祖父江秀明, 佐川里紗, 笠原亜希子, 金下峻也, 藤岡数記, 村上憲, 藤井渉, 和田誠 …

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 549-549, Mar, 2017
その他関節リウマチの治療薬の使用に関する患者実態調査

北村治子, 妹尾高宏, 金下峻也, 井上拓也, 佐川里紗, 笠原亜希子, 藤岡数記, 遠山将吾, 谷口大吾, 和田誠 …

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 571-571, Mar, 2017
多臓器に病変を認めたIgG4関連疾患の1例

北川裕子, 祖父江秀晃, 金下峻也, 笠原亜希子, 佐川里紗, 藤岡数記, 和田誠, 妹尾高宏, 河野正孝, 川人豊

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 692-692, Mar, 2017
腸管ベーチェット病に脳梗塞、大動脈瘤を認めた1例

祖父江秀晃, 藤岡数記, 村上憲, 北川裕子, 井上拓也, 笠原亜希子, 金下峻也, 佐川里紗, 藤井渉, 妹尾高宏 …

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 694-694, Mar, 2017
脳病変を伴った抗MDA5抗体陽性clinically amyopathic dermatomyositis(CADM)の1例

藤岡数記, 北川裕子, 祖父江秀晃, 金下峻也, 和田誠, 妹尾高宏, 河野正孝, 川人豊

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 754-754, Mar, 2017
播種性ノカルジア症を発症した無筋炎性皮膚筋炎(CADM)の一例

和田誠, 北川裕子, 祖父江秀晃, 金下峻也, 藤岡数記, 村上憲, 藤井渉, 妹尾高宏, 河野正孝, 川人豊

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 769-769, Mar, 2017
マウスブレオマイシン誘導肺線維症におけるAIF-1の役割

永原秀剛, 妹尾高宏, 井上拓也, 木田節, 中林周, 茎田祐司, 藤岡数記, 和田誠, 河野正孝, 川人豊

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 782-782, Mar, 2017
関節リウマチに対する漢方治療併用の有用性

谷口大吾, 小田良, 遠山将吾, 妹尾高宏, 川人豊, 徳永大作, 久保俊一

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 806-806, Mar, 2017
梅毒による椎体・上腕骨の骨炎を認めた一例

金下峻也, 和田誠, 北川裕子, 祖父江秀晃, 笠原亜希子, 佐川里紗, 藤岡数記, 妹尾高宏, 遠山将吾, 小田良 …

日本リウマチ学会総会・学術集会プログラム・抄録集, 61回 850-850, Mar, 2017
MRI of Bilateral Hands Prevents Clinicians from Failing to Detect Joint Damage of Patients with Rheumatoid Arthritis Compared to Scanning Unilateral Hand

Yuji Kukida, Akiko Kasahara, Takahiro Seno, Takuya Inoue, Risa Sagawa, Takashi Kida, Amane Nakabayashi, Hidetake Nagahara, Ken Murakami, Satoshi Morita …

ARTHRITIS & RHEUMATOLOGY, 68, Oct, 2016
【関節リウマチ早期診断・治療のための必須知識】RAと鑑別すべき疾患全身性結合組織病

妹尾高宏, 川人豊

Orthopaedics, 29(7) 43-51, Jul, 2016
A NEW DISEASE ACTIVITY BIOMARKER ALTERNATIVE TO CRP UNDER TOCILIZUMAB THERAPY FOR RHEUMATOID ARTHRITIS VIA PEPTIDOMIC ANALYSIS

T. Seno, D. Nonaka, M. Kohno, H. Sofue, A. Kasahara, R. Sagawa, T. Kida, Y. Kukida, K. Fujioka, W. Fujii …

ANNALS OF THE RHEUMATIC DISEASES, 75 982-982, Jun, 2016

Books and Other Publications

Rheumatology

Takahiro Seno, Yutaka Kawahito (Role: Joint author, Management of RA with comorbidities.)

Kagakuhyoronsha, Dec, 2022

Presentations

Sphingosine-1-phosphate signaling regulates neutrophil functions

North American Vascular Biology Organization, Oct 14, 2018

Major Professional Memberships

Japanese College of Rheumatology

Research Projects

Novel therapeutic development of ANCA-associated vasculitis based on sphingosine-1-phosphate signaling.

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025

Media Coverage

禁煙外来、丹波でも再開補助薬不足を解消

京都新聞社, 京都新聞, Jan, 2011 Newspaper, magazine
禁煙外来効果のほどは

京都新聞社, 京都新聞, Nov, 2010 Newspaper, magazine

Profile Information

Research Interests

Major Research Areas

Major Research History

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Presentations

Major Professional Memberships

Research Projects

Media Coverage

Menu

Coauthors